BR9711611A - M-todo para a redu-Æo de variabilidade de expressÆo de transgenes em c-lulas de planta - Google Patents

M-todo para a redu-Æo de variabilidade de expressÆo de transgenes em c-lulas de planta

Info

Publication number
BR9711611A
BR9711611A BR9711611A BR9711611A BR9711611A BR 9711611 A BR9711611 A BR 9711611A BR 9711611 A BR9711611 A BR 9711611A BR 9711611 A BR9711611 A BR 9711611A BR 9711611 A BR9711611 A BR 9711611A
Authority
BR
Brazil
Prior art keywords
transgenes
variability
expression
reducing
plant cells
Prior art date
Application number
BR9711611A
Other languages
English (en)
Inventor
William F Thompson
George C Allen
Scots L Mankin
Original Assignee
Univ North Carolina State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina State filed Critical Univ North Carolina State
Publication of BR9711611A publication Critical patent/BR9711611A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/822Reducing position variability, e.g. by the use of scaffold attachment region/matrix attachment region (SAR/MAR); Use of SAR/MAR to regulate gene expression

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
BR9711611A 1996-08-01 1997-07-31 M-todo para a redu-Æo de variabilidade de expressÆo de transgenes em c-lulas de planta BR9711611A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/692,847 US6037525A (en) 1996-08-01 1996-08-01 Method for reducing expression variability of transgenes in plant cells
PCT/US1997/013687 WO1998005757A1 (en) 1996-08-01 1997-07-31 Method for reducing expression variability of transgenes in plant cells

Publications (1)

Publication Number Publication Date
BR9711611A true BR9711611A (pt) 1999-08-24

Family

ID=24782276

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9711611A BR9711611A (pt) 1996-08-01 1997-07-31 M-todo para a redu-Æo de variabilidade de expressÆo de transgenes em c-lulas de planta

Country Status (8)

Country Link
US (2) US6037525A (pt)
EP (1) EP0915966A4 (pt)
JP (1) JP2000515748A (pt)
AU (1) AU719306B2 (pt)
BR (1) BR9711611A (pt)
CA (1) CA2262815A1 (pt)
NZ (1) NZ333998A (pt)
WO (1) WO1998005757A1 (pt)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3777416B2 (ja) * 1998-12-09 2006-05-24 国立大学法人 奈良先端科学技術大学院大学 植物において外来遺伝子を安定に発現させる導入方法
US7126041B1 (en) 1999-12-10 2006-10-24 North Carolina State Unversity High efficiency gene targeting in plants
DE10049587A1 (de) * 2000-10-06 2002-05-02 Icon Genetics Ag Vektorsystem für Pflanzen
AU2002211615A1 (en) * 2000-10-20 2002-05-06 University Of Kentucky Research Foundation Genetic insulator for preventing influence by another gene promoter
DE10061150A1 (de) 2000-12-08 2002-06-13 Icon Genetics Ag Verfahren und Vektoren zur Erzeugung von transgenen Pflanzen
EP2138583A1 (en) 2000-12-22 2009-12-30 Institut National De La Recherche Agronomique Position-independent and tissue specific expression of a transgene in milk of transgenic animals
DE10102389A1 (de) 2001-01-19 2002-08-01 Icon Genetics Ag Verfahren und Vektoren zur Plastidentransformation höherer Pflanzen
DE10114209A1 (de) * 2001-03-23 2002-12-05 Icon Genetics Ag Ortsgerichtete Transformation durch Verwendung von Amplifikationsvektoren
DE10115507A1 (de) * 2001-03-29 2002-10-10 Icon Genetics Ag Verfahren zur Kodierung von Information in Nukleinsäuren eines genetisch veränderten Organismus
DE10121283B4 (de) 2001-04-30 2011-08-11 Icon Genetics GmbH, 80333 Verfahren und Vektoren zur Amplifikation oder Expression von gewünschten Nucleinsäuresequenzen in Pflanzen
US6498587B1 (en) * 2001-06-13 2002-12-24 Ethertronics Inc. Compact patch antenna employing transmission lines with insertable components spacing
DE60236333D1 (de) * 2001-07-04 2010-06-17 Chromagenics Bv DNS-Sequenzen mit anti-repressor Aktivität
DE10132780A1 (de) * 2001-07-06 2003-01-16 Icon Genetics Ag Plastidäre Genexpression über autonom replizierende Vektoren
DE10143238A1 (de) * 2001-09-04 2003-03-20 Icon Genetics Ag Identifizierung eukaryotischer interner Ribosomen-Eingangsstellen (IRES)-Elemente
DE10143205A1 (de) * 2001-09-04 2003-03-20 Icon Genetics Ag Verfahren zur Proteinproduktion in Pflanzen
DE10143237A1 (de) * 2001-09-04 2003-03-20 Icon Genetics Ag Herstellung künstlicher interner ribosomaler Eingangsstellenelemente (Ires-Elemente)
US6661380B1 (en) 2002-04-05 2003-12-09 Centurion Wireless Technologies, Inc. Multi-band planar antenna
US20040016015A1 (en) * 2002-07-17 2004-01-22 Nguyen Thanh-Tuyen T. High efficiency germline transformation system
US20040016014A1 (en) * 2002-07-17 2004-01-22 Nguyen Thanh-Tuyen T. High efficiency germline transformation system
JP4300271B2 (ja) * 2002-10-16 2009-07-22 独立行政法人農業生物資源研究所 ウニ由来インスレーターを用いた遺伝子発現ベクター
US6939636B2 (en) * 2003-04-28 2005-09-06 Relion, Inc. Air cooled fuel cell module
OA13241A (en) * 2003-08-19 2007-01-31 22Nd Century Ltd Llc Reduced-exposure tobacco products.
RU2008102646A (ru) * 2005-06-24 2009-07-27 Риджентс Оф Дзе Юниверсити Оф Миннесота (Us) Применение цитозиндезаминаз для уменьшения переноса ретроэлементов от свиней человеку
US7655786B2 (en) * 2006-03-15 2010-02-02 E.I. Du Pont De Nemours And Company Gene expression modulating element
CA2651423A1 (en) * 2006-03-23 2007-10-04 The Regents Of The University Of Michigan Compositions and methods for generating transgenic animals
WO2010008564A2 (en) * 2008-07-16 2010-01-21 Recombinetics Plaice dna transposon system
WO2010008562A2 (en) * 2008-07-16 2010-01-21 Recombinetics Methods and materials for producing transgenic animals
BR112012020257A8 (pt) 2010-02-11 2018-02-14 Recombinetics Inc métodos e aparelhos para produzir artiodátilos transgênicos
US10920242B2 (en) 2011-02-25 2021-02-16 Recombinetics, Inc. Non-meiotic allele introgression
JP2014509195A (ja) 2011-02-25 2014-04-17 リコンビネティクス・インコーポレイテッド 遺伝子改変動物、およびそれを作製する方法
WO2013038294A1 (en) * 2011-09-15 2013-03-21 Basf Plant Science Company Gmbh Regulatory nucleic acid molecules for reliable gene expression in plants
EA201790757A1 (ru) 2011-09-22 2017-07-31 Эмджен Инк. Связывающие антиген cd27l белки
UY34813A (es) 2012-05-18 2013-11-29 Amgen Inc Proteínas de unión a antígeno dirigidas contra el receptor st2
US10058078B2 (en) 2012-07-31 2018-08-28 Recombinetics, Inc. Production of FMDV-resistant livestock by allele substitution
US20140141065A1 (en) 2012-11-19 2014-05-22 Discovery Genomics, Inc. Method to achieve extended expression of dna infused into liver
UY35148A (es) 2012-11-21 2014-05-30 Amgen Inc Immunoglobulinas heterodiméricas
US9580486B2 (en) 2013-03-14 2017-02-28 Amgen Inc. Interleukin-2 muteins for the expansion of T-regulatory cells
WO2014144817A2 (en) 2013-03-15 2014-09-18 Amgen Inc. Inhibitory polypeptides specific to wnt inhibitors
NZ713636A (en) 2013-05-30 2022-07-01 Kiniksa Pharmaceuticals Ltd Oncostatin m receptor antigen binding proteins
AU2014318017B2 (en) 2013-09-05 2020-02-06 Amgen Inc. Fc-containing molecules exhibiting predictable, consistent, and reproducible glycoform profiles
US20170142942A1 (en) 2014-07-14 2017-05-25 Washington State University Nanos knock-out that ablates germline cells
IL283764B2 (en) 2015-04-10 2024-01-01 Amgen Inc Interleukin for the expansion of myotonic control T-2 cells
AU2016252773B2 (en) 2015-04-24 2022-06-02 Genentech, Inc. Multispecific antigen-binding proteins
LT3331355T (lt) 2015-08-06 2024-07-25 The Curators Of The University Of Missouri Kiaulių reprodukcinio ir respiracinio sindromo virusui (prrsv) atsparios kiaulės ir ląstelės, turinčios modifikuotus cd163 genus
KR102645625B1 (ko) 2015-09-22 2024-03-07 제넨테크, 인크. Fc-함유 단백질의 발현
JP6932693B2 (ja) 2015-10-08 2021-09-08 ザイムワークス,インコーポレイテッド カッパ及びラムダ軽鎖を含む抗原結合ポリペプチド構築物及びその使用
MX2018004831A (es) 2015-11-02 2018-08-01 Genentech Inc Metodos para confeccionar formas fucosiladas y afucosiladas de una proteina.
CN115073581A (zh) 2016-05-04 2022-09-20 美国安进公司 用于扩增t调节性细胞的白细胞介素-2突变蛋白
WO2019000105A1 (en) 2017-06-30 2019-01-03 Zymeworks Inc. STABILIZED CHIMERIC FABES
CN114555634A (zh) 2019-08-13 2022-05-27 美国安进公司 用于扩增调节性t细胞的白介素-2突变蛋白
EP3782465B1 (en) 2019-08-23 2023-08-30 Universität Potsdam Transgenic zebrafish model for stroke
KR20220114595A (ko) 2019-12-17 2022-08-17 암젠 인크 치료에서의 사용을 위한 이중 인터류킨-2/tnf 수용체 효현제
CN117042600A (zh) 2020-11-16 2023-11-10 猪改良英国有限公司 具有经编辑的anp32基因的抗甲型流感动物
WO2023105244A1 (en) 2021-12-10 2023-06-15 Pig Improvement Company Uk Limited Editing tmprss2/4 for disease resistance in livestock

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE217319T1 (de) * 1992-10-05 2002-05-15 Univ North Carolina State Verfahren zur erhöhung der expression und zur verminderung der expressionsvariabilität von fremdgenen in pflanzenzellen
US5610053A (en) * 1993-04-07 1997-03-11 The United States Of America As Represented By The Department Of Health And Human Services DNA sequence which acts as a chromatin insulator element to protect expressed genes from cis-acting regulatory sequences in mammalian cells
WO1994023046A1 (en) * 1993-04-07 1994-10-13 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services Dna sequence which acts as a chromatin insulator element to protect expressed genes from cis-acting regulatory sequences in mammalian cells
AU6679094A (en) * 1993-04-19 1994-11-08 Sandoz Ltd. Genetic stabilizing elements

Also Published As

Publication number Publication date
JP2000515748A (ja) 2000-11-28
AU719306B2 (en) 2000-05-04
AU3907097A (en) 1998-02-25
EP0915966A1 (en) 1999-05-19
CA2262815A1 (en) 1998-02-12
WO1998005757A1 (en) 1998-02-12
NZ333998A (en) 2000-01-28
US6037525A (en) 2000-03-14
US6100448A (en) 2000-08-08
EP0915966A4 (en) 2002-07-24

Similar Documents

Publication Publication Date Title
BR9711611A (pt) M-todo para a redu-Æo de variabilidade de expressÆo de transgenes em c-lulas de planta
BR9607622A (pt) Método para preparar um heteromultímero heteromultímero composição célula hospedeira e método para preparar um heteromultímero
DK0955455T3 (da) Fremgangsmåde til energiproduktion og energiproduktionsanlæg
IL129464A (en) Leaf-specific gene expression in transgenic plants
ZA989517B (en) In planta method for the production of transgenic plants.
DE59809002D1 (de) Verfahren zum betreiben einer windenergieanlage sowie windenergieanlage
DE59810098D1 (de) Windenergieanlage
GB2313580B (en) An aircraft power plant
KR960012687A (ko) 발전설비 및 그 제어방법
AU2024797A (en) Improvement in the method and plant for manufacturing thermoplastic-resin parisons
FI962726A (fi) Mega-tuulivoimala
DE69631886D1 (de) Reformierungsanlage
AUPP041097A0 (en) Method for inducing stress tolerance in plant material
DE59906116D1 (de) System zur energie- und datenverteilung in energieverteilungsanlagen
DE69615653D1 (de) Blühende Pflanzenkultur
FI972336A0 (fi) Biotiinin lisääntynyt biosynteesi kasvisolukossa
EP1003849A4 (en) METHOD FOR REDUCING THE EXPRESSION VARIANCE OF TRANSGENES IN PLANT CELLS
NO964898D0 (no) Elektrokjemisk anlegg
HUP9702354A3 (en) Method to control plant fungal diseases
FI963021A0 (fi) Kasvien viljelymenetelmä
NO20002436D0 (no) Sammensetning og fremgangsmÕte for fjerning av fosfationinnholdet i vann
IT1292498B1 (it) Metodo ed impianto per la mitilicoltura
PL340754A1 (en) Method activating haemoblast-type stem cells
ZA975120B (en) Floating power plant
DE69619856D1 (de) Kraftwerk

Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1882 DE 30/01/2007.