BR9604907B1 - derivados de nucleosidios homocarbociclico de pirimidinodiona substituìda antiviral e composição contendo derivados de nucleosidios homocarbociclico de pirimidinodiona substituìda antiviral com princìpios ativos. - Google Patents
derivados de nucleosidios homocarbociclico de pirimidinodiona substituìda antiviral e composição contendo derivados de nucleosidios homocarbociclico de pirimidinodiona substituìda antiviral com princìpios ativos.Info
- Publication number
- BR9604907B1 BR9604907B1 BRPI9604907-3A BR9604907A BR9604907B1 BR 9604907 B1 BR9604907 B1 BR 9604907B1 BR 9604907 A BR9604907 A BR 9604907A BR 9604907 B1 BR9604907 B1 BR 9604907B1
- Authority
- BR
- Brazil
- Prior art keywords
- homocarbocyclic
- atom
- pct
- substituted
- nucleoside derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR19960004189 | 1996-02-22 | ||
| KR19960025441 | 1996-06-28 | ||
| KR1019960047459A KR100197792B1 (ko) | 1996-06-28 | 1996-10-22 | 신규 항바이러스성 2-비스 (하이드록시메틸) 사이클로프로판-1- 메틸 피리미딘디온 유도체 및 그의 제조방법 |
| KR1019960047458A KR100197791B1 (ko) | 1996-02-22 | 1996-10-22 | 신규 항바이러스성 6위치에 치환된 피리미딘디온호모 카보사이 클릭 뉴클레오시드 유도체 및 그의 제조방법 |
| PCT/KR1996/000265 WO1997030979A1 (en) | 1996-02-22 | 1996-12-30 | New antiviral substituted pyrimidinedione homocarbocyclic nucleoside derivatives and methods for the preparation thereof and compositions containing the same as active ingredients |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR9604907A BR9604907A (pt) | 1998-07-21 |
| BR9604907B1 true BR9604907B1 (pt) | 2011-10-18 |
| BRPI9604907B8 BRPI9604907B8 (pt) | 2016-11-08 |
Family
ID=27483113
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI9604907A BRPI9604907B8 (pt) | 1996-02-22 | 1996-12-30 | derivados de nucleosidios homocarbociclico de pirimidinodiona substituída antiviral e composição contendo derivados de nucleosidios homocarbociclico de pirimidinodiona substituída antiviral com princípios ativos. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5922727A (pt) |
| EP (1) | EP0827498B1 (pt) |
| JP (1) | JP3049095B2 (pt) |
| CN (1) | CN1092647C (pt) |
| AT (1) | ATE243202T1 (pt) |
| AU (1) | AU710490B2 (pt) |
| BR (1) | BRPI9604907B8 (pt) |
| CA (1) | CA2217026C (pt) |
| DE (1) | DE69628750T2 (pt) |
| ID (1) | ID15963A (pt) |
| MX (1) | MX9708110A (pt) |
| RU (1) | RU2138487C1 (pt) |
| TW (1) | TW494098B (pt) |
| WO (1) | WO1997030979A1 (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19826517B4 (de) * | 1998-06-15 | 2006-03-23 | Baxter Healthcare S.A. | Verfahren zur Herstellung von Filmtabletten mit Cyclophosphamid als Wirkstoff und daraus hergestellte Cyclophosphamid-Filmtablette |
| US6713486B1 (en) * | 1999-03-04 | 2004-03-30 | Korea Research Institute Of Chemical Technology | Antiviral 2,4-pyrimidinedione derivatives and process for the preparation thereof |
| KR100311949B1 (ko) | 1999-03-10 | 2001-11-02 | 최승주 | 1-[(사이클로펜트-3-엔-1-일)메틸]-5-에틸-6-(3,5-다이메틸벤조일)-2,4-피리미딘다이온의제조방법 |
| KR20000065885A (ko) * | 1999-04-10 | 2000-11-15 | 최승주 | 항바이러스성 피리미딘다이온 유도체 및 그 제조방법 |
| KR101237312B1 (ko) | 2006-02-10 | 2013-03-04 | 삼진제약주식회사 | 피리미딘다이온 유도체를 포함하는 ｃ형 간염의 예방 및치료용 약학 조성물 |
| MX2009000871A (es) * | 2006-07-24 | 2009-05-08 | Gilead Sciences Inc | Novedosos inhibidores de transcriptasa inversa de vih. |
| MX2009013804A (es) * | 2007-06-29 | 2010-02-03 | Korea Res Inst Chem Tech | Inhibidores novedosos de transcriptasa inversa de vih. |
| US8354421B2 (en) * | 2007-06-29 | 2013-01-15 | Korea Research Insitute Of Chemical Technology | HIV reverse transcriptase inhibitors |
| US8119800B2 (en) * | 2007-12-21 | 2012-02-21 | Korea Research Institute Of Chemical Technology | Processes for preparing HIV reverse transcriptase inhibitors |
| CN102603652A (zh) * | 2011-12-27 | 2012-07-25 | 河南师范大学 | 5-甲酰基嘧啶碳环核苷及制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4730001A (en) * | 1986-01-22 | 1988-03-08 | Southern Research Institute | Carbocyclic analogues of amino and azido thymidines |
| HU205917B (en) * | 1989-09-29 | 1992-07-28 | Mitsubishi Chem Ind | Process for producing 6-substituted pyrimidine derivatives and antiviral pharmaceutical compositions containing them as active components |
| DE69126469T2 (de) * | 1990-03-29 | 1998-01-29 | Mitsubishi Chem Corp | Pyrimidin-Nukleosid-Derivate und antivirale Mittel, die diese Derivate als aktiven Bestandteil enthalten |
| AU1994492A (en) * | 1991-07-22 | 1993-02-23 | Baker Cummins Pharmaceuticals, Inc. | Acyclic 6-phenylselenenyl pyrimidine nucleosides |
| KR950011530A (ko) * | 1993-10-21 | 1995-05-15 | 도바 다다스 | 사이클로프로판 유도체 및 이를 함유하는 항바이러스제 |
| KR0151811B1 (ko) * | 1993-12-21 | 1998-10-15 | 강박광 | 신규한 항바이러스성 2,4-피리미딘디온 유도체 및 그의 제조방법 |
-
1996
- 1996-12-30 RU RU97118134A patent/RU2138487C1/ru active
- 1996-12-30 AT AT96943370T patent/ATE243202T1/de not_active IP Right Cessation
- 1996-12-30 WO PCT/KR1996/000265 patent/WO1997030979A1/en active IP Right Grant
- 1996-12-30 AU AU12124/97A patent/AU710490B2/en not_active Expired
- 1996-12-30 EP EP96943370A patent/EP0827498B1/en not_active Expired - Lifetime
- 1996-12-30 CA CA002217026A patent/CA2217026C/en not_active Expired - Lifetime
- 1996-12-30 JP JP9530013A patent/JP3049095B2/ja not_active Expired - Lifetime
- 1996-12-30 BR BRPI9604907A patent/BRPI9604907B8/pt active IP Right Grant
- 1996-12-30 US US08/945,121 patent/US5922727A/en not_active Expired - Lifetime
- 1996-12-30 DE DE69628750T patent/DE69628750T2/de not_active Expired - Lifetime
- 1996-12-30 CN CN96193400A patent/CN1092647C/zh not_active Expired - Lifetime
-
1997
- 1997-02-19 ID IDP970469A patent/ID15963A/id unknown
- 1997-02-20 TW TW086102026A patent/TW494098B/zh not_active IP Right Cessation
- 1997-10-21 MX MX9708110A patent/MX9708110A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0827498A1 (en) | 1998-03-11 |
| ATE243202T1 (de) | 2003-07-15 |
| EP0827498B1 (en) | 2003-06-18 |
| ID15963A (id) | 1997-08-21 |
| JPH10507780A (ja) | 1998-07-28 |
| CN1092647C (zh) | 2002-10-16 |
| WO1997030979A1 (en) | 1997-08-28 |
| BR9604907A (pt) | 1998-07-21 |
| JP3049095B2 (ja) | 2000-06-05 |
| CA2217026A1 (en) | 1997-08-28 |
| RU2138487C1 (ru) | 1999-09-27 |
| CN1182420A (zh) | 1998-05-20 |
| BRPI9604907B8 (pt) | 2016-11-08 |
| DE69628750D1 (de) | 2003-07-24 |
| MX9708110A (es) | 1998-06-30 |
| AU1212497A (en) | 1997-09-10 |
| TW494098B (en) | 2002-07-11 |
| US5922727A (en) | 1999-07-13 |
| CA2217026C (en) | 2001-11-20 |
| DE69628750T2 (de) | 2004-04-29 |
| AU710490B2 (en) | 1999-09-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD5 | Application fees: dismissal - article 86 of industrial property law | ||
| B08G | Application fees: restoration [chapter 8.7 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, DE ACORDO COM ARTIGO 37, TENDO POR BASE OS ARTIGOS 24 E 25 DA LPI 9279 DE 14/05/96. |
|
| B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 18/10/2011, OBSERVADAS AS CONDICOES LEGAIS. |
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| B22O | Other matters related to patents and certificates of addition of invention: legal action concerning patent |
Free format text: INPI-52400.68486/2013 ORIGEM: JUIZO DA 25A VARA FEDERAL DE SAO PAULO PROCESSO NO 0017574-93.2013.4.03.6100 ACAO DE NULIDADE DE PATENTE AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL - INPI REU: BAYER SAS, CENTELION E CENTELION S.A., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, MERCK SERONO S.A. E SAMJIN PHARMACEUTICAL CO. LTD. |
|
| B25G | Requested change of headquarter approved | ||
| B19A | Notification of judicial decision: notification of judicial decision |
Free format text: INPI-52400.068486/2013 SECAO JUDICIARIA DE SAO PAULO - 25A VARA FEDERAL CIVEL DE SAO PAULO PROCESSO NO0017574-93.2013.403.6100 AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL - INPI REU: BAYER SAS, CENTELION, CENTELION S.A, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, MERCK SERONO S.A E SAMJIN PHARMACEUTICAL CO. LTDA DECISAO: JULGO PROCEDENTE O PEDIDO FORMULADO PARA DECLARAR A NULIDADE PARCIAL DAS PATENTES PI 9607583-0, PI 9610511-9, PI 9707889-1 E PI 9604907-3 E DETERMINO A RETIFICACAO DOS RESPECTIVOS PRAZOS DE VIGENCIA DE MODO A OBSERVAR A O DISPOSTO NO PARAGRAFO UNICO DO ARTIGO 229 DA LEI NO 9.279-96, EM INTERPRETACAO CONJUNTA COM O CAPUT DO ARTIGO 40 DO MESMO DIPLOMA. |
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| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: REFERENTE A RPI 2128 DE 18/10/2011, QUANTO AO PRAZO DE VALIDADE POR DETERMINACAO DA 25A VARA CIVEL FEDERAL DE SAO PAULO, PROC. 0017574-93.2013.403.6100 - ACAO ORDINARIA - INPI 52400.068486/2013-05. |