BR8403068A - Compostos,processo para sua preparacao,composicoes farmaceuticas e uso dos ditos compostos - Google Patents
Compostos,processo para sua preparacao,composicoes farmaceuticas e uso dos ditos compostosInfo
- Publication number
- BR8403068A BR8403068A BR8403068A BR8403068A BR8403068A BR 8403068 A BR8403068 A BR 8403068A BR 8403068 A BR8403068 A BR 8403068A BR 8403068 A BR8403068 A BR 8403068A BR 8403068 A BR8403068 A BR 8403068A
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- hydrogen
- formula
- lower alkyl
- chem
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Transformer Cooling (AREA)
- Feeding And Controlling Fuel (AREA)
- Discharging, Photosensitive Material Shape In Electrophotography (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Hydrogenated Pyridines (AREA)
- Steroid Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50738383A | 1983-06-24 | 1983-06-24 | |
| US67419385A | 1985-01-18 | 1985-01-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR8403068A true BR8403068A (pt) | 1985-05-28 |
Family
ID=37102508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR8403068A BR8403068A (pt) | 1983-06-24 | 1984-06-22 | Compostos,processo para sua preparacao,composicoes farmaceuticas e uso dos ditos compostos |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4650812A (pt) |
| EP (2) | EP0129906B1 (pt) |
| JP (2) | JPS6019782A (pt) |
| KR (1) | KR920001776B1 (pt) |
| AT (1) | ATE34981T1 (pt) |
| AU (2) | AU565490B2 (pt) |
| BR (1) | BR8403068A (pt) |
| CS (1) | CS246085B2 (pt) |
| DE (1) | DE3471933D1 (pt) |
| DK (1) | DK304784A (pt) |
| ES (2) | ES533678A0 (pt) |
| FI (1) | FI87207C (pt) |
| GR (1) | GR82135B (pt) |
| HU (1) | HU202512B (pt) |
| IL (1) | IL72187A (pt) |
| MC (1) | MC1596A1 (pt) |
| NO (1) | NO168643C (pt) |
| NZ (1) | NZ208610A (pt) |
| PH (1) | PH20806A (pt) |
| PT (1) | PT78779A (pt) |
| ZA (1) | ZA844519B (pt) |
| ZW (1) | ZW9884A1 (pt) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU548450B2 (en) * | 1983-08-08 | 1985-12-12 | G.D. Searle & Co. | Substituted dihydrobenzopyrans |
| US4565882A (en) * | 1984-01-06 | 1986-01-21 | G. D. Searle & Co. | Substituted dihydrobenzopyran-2-carboxylates |
| US4885309A (en) * | 1986-08-01 | 1989-12-05 | Hoffmann-La Roche Inc. | Therapeutic treatment of leukotriene-mediated dermal inflammation by topical administration of 3,4-dihydro-2H-1-benzopyran derivatives |
| ZA875319B (en) * | 1986-08-15 | 1988-02-15 | F. Hoffmann-La Roche & Co. Aktiengesellschaft | Use of dihydro benzopyran derivatives |
| US4874777A (en) * | 1987-04-10 | 1989-10-17 | Eli Lilly And Company | Leukotriene antagonists |
| US4853398A (en) * | 1987-04-13 | 1989-08-01 | Eli Lilly And Company | Leukotriene antagonists and use thereas |
| US4889871A (en) * | 1987-05-29 | 1989-12-26 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives |
| AT392902B (de) * | 1987-10-08 | 1991-07-10 | Hoffmann La Roche | Pharmazeutische verwendung von phenoxypentyloxy-3,4-dihydro-2h-1-benzopyran- derivaten |
| US5037747A (en) * | 1988-01-26 | 1991-08-06 | Hoffmann-La Roche Inc. | Production of benzopyran-2-carboxylic acids and esters by enzymatic hydrolysis |
| EP0336068A1 (en) * | 1988-02-11 | 1989-10-11 | F. Hoffmann-La Roche Ag | Phenoxyalkoxy-3,4-dihydro-2H-1-benzopyran derivatives |
| US5093353A (en) * | 1988-05-20 | 1992-03-03 | G. D. Searle & Co. | 2,2-di-substituted benzopyran leukotriene-D4 antagonists |
| US4950684A (en) * | 1988-05-20 | 1990-08-21 | G. D. Searle & Co. | 2,2-di-substituted benzopyran leukotriene-D4 antagonists |
| US5219883A (en) * | 1988-05-20 | 1993-06-15 | G. D. Searle & Co. | 2,2-di-substituted benzopyran leukotriene-D4 antagonists |
| US4931574A (en) * | 1988-08-23 | 1990-06-05 | Hoffmann-La Roche Inc. | Process for the preparation of benzopyrans |
| JPH0366669A (ja) * | 1989-08-03 | 1991-03-22 | Shionogi & Co Ltd | 複素環式化合物 |
| US5192782A (en) * | 1990-05-10 | 1993-03-09 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof |
| US5073562A (en) * | 1990-05-10 | 1991-12-17 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof |
| US5212198A (en) * | 1990-05-10 | 1993-05-18 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof |
| US5124350A (en) * | 1990-06-28 | 1992-06-23 | G. D. Searle & Co. | Leukotriene b4 antagonists |
| US5273999A (en) * | 1991-09-10 | 1993-12-28 | Hoffmann-La Roche Inc. | Carboxylic acid leukotriene B4 antagonists |
| PH30449A (en) * | 1991-11-25 | 1997-05-28 | Lilly Co Eli | Substituted phenyl phenol leukotriene antagonists |
| US5380740A (en) * | 1993-04-28 | 1995-01-10 | G. D. Searle & Co. | Anti-inflammatory compounds, compositions and method of use thereof |
| US5527827A (en) * | 1994-10-27 | 1996-06-18 | Merck Frosst Canada, Inc. | Bisarylcarbinol cinnamic acids as inhibitors of leukotriene biosynthesis |
| US6051586A (en) * | 1997-12-19 | 2000-04-18 | Bayer Corporation | Sulfonamide substituted chroman derivatives useful as beta 3 adrenoreceptor agonists |
| US6469031B1 (en) | 1998-12-18 | 2002-10-22 | Bayer Corporation | Carboxyl substituted chroman derivatives useful as beta 3 adrenoreceptor agonists |
| JP2004513090A (ja) | 2000-09-27 | 2004-04-30 | メルク エンド カムパニー インコーポレーテッド | 糖尿病及び脂質異常症の治療のためのベンゾピランカルボン酸誘導体 |
| EP1347755A2 (en) | 2000-10-31 | 2003-10-01 | Merck & Co., Inc. | Benzopyrancarboxylic acid derivatives for the treatment of diabetes and lipid disorders |
| AR035605A1 (es) | 2000-12-11 | 2004-06-16 | Bayer Corp | Derivados de aminometil cromano di-sustituidos, un metodo para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la manufactura de medicamentos utiles como agonistas beta-3-adreno-receptores |
| AR035858A1 (es) | 2001-04-23 | 2004-07-21 | Bayer Corp | Derivados de cromano 2,6-sustituidos,composiciones farmaceuticas,uso de dichos derivados para la manufactura de medicamentos utiles como agonistas adrenorreceptores beta-3 |
| WO2003024948A1 (en) | 2001-09-14 | 2003-03-27 | Bayer Pharmaceuticals Corporation | Benzofuran and dihydrobenzofuran derivatives useful as beta-3 adrenoreceptor agonists |
| KR101233223B1 (ko) * | 2004-12-21 | 2013-02-14 | 제이엔씨 석유 화학 주식회사 | 크로만환을 가지는 액정 화합물, 액정 조성물 및 이 액정조성물을 함유하는 액정 표시소자 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4133889A (en) * | 1971-07-29 | 1979-01-09 | Fisons, Ltd. | 2(5-Tetrazolyl)chromones |
| GB1384530A (en) * | 1971-07-29 | 1975-02-19 | Fisons Ltd | Chromone derivatives |
| SU469247A3 (ru) * | 1972-01-14 | 1975-04-30 | Майлз Лабораториз Инк (Фирма) | Способ получени производных хромона |
| ZA739471B (en) * | 1972-12-22 | 1974-08-28 | Hoffmann La Roche | Chromane derivatives |
| US4150050A (en) * | 1978-01-30 | 1979-04-17 | Hoffmann-La Roche Inc. | 3,6-Dioxo-1,4-cyclohexadien-1-yl-butandate esters |
| DE3265715D1 (en) * | 1981-03-24 | 1985-10-03 | Fisons Plc | Anti srs-a carboxylic acid derivatives, processes for their production and pharmaceutical formulations containing them |
| US4474788A (en) * | 1981-11-12 | 1984-10-02 | Fisons Plc | Anti-SRSA quinoline carboxylic acid derivatives |
| AU548450B2 (en) * | 1983-08-08 | 1985-12-12 | G.D. Searle & Co. | Substituted dihydrobenzopyrans |
| US4546194A (en) * | 1984-05-29 | 1985-10-08 | G. D. Searle & Co. | Substituted chromanon-2-yl alkanols and derivatives thereof |
-
1984
- 1984-06-14 ZA ZA844519A patent/ZA844519B/xx unknown
- 1984-06-20 PT PT78779A patent/PT78779A/pt not_active IP Right Cessation
- 1984-06-20 FI FI842497A patent/FI87207C/fi not_active IP Right Cessation
- 1984-06-21 IL IL72187A patent/IL72187A/xx unknown
- 1984-06-21 NZ NZ208610A patent/NZ208610A/en unknown
- 1984-06-21 DK DK304784A patent/DK304784A/da not_active Application Discontinuation
- 1984-06-22 NO NO84842549A patent/NO168643C/no unknown
- 1984-06-22 BR BR8403068A patent/BR8403068A/pt unknown
- 1984-06-22 GR GR75089A patent/GR82135B/el unknown
- 1984-06-22 MC MC841711A patent/MC1596A1/xx unknown
- 1984-06-22 AU AU29785/84A patent/AU565490B2/en not_active Ceased
- 1984-06-22 PH PH30874A patent/PH20806A/en unknown
- 1984-06-22 ZW ZW98/84A patent/ZW9884A1/xx unknown
- 1984-06-22 HU HU842427A patent/HU202512B/hu not_active IP Right Cessation
- 1984-06-22 CS CS844772A patent/CS246085B2/cs unknown
- 1984-06-23 JP JP59128475A patent/JPS6019782A/ja active Granted
- 1984-06-23 KR KR1019840003570A patent/KR920001776B1/ko not_active IP Right Cessation
- 1984-06-23 ES ES533678A patent/ES533678A0/es active Granted
- 1984-06-25 DE DE8484107289T patent/DE3471933D1/de not_active Expired
- 1984-06-25 EP EP84107289A patent/EP0129906B1/de not_active Expired
- 1984-06-25 AT AT84107289T patent/ATE34981T1/de active
-
1985
- 1985-01-18 US US06/692,479 patent/US4650812A/en not_active Expired - Fee Related
- 1985-03-29 ES ES541709A patent/ES8602741A1/es not_active Expired
-
1986
- 1986-09-19 EP EP86112944A patent/EP0261254B1/en not_active Expired - Lifetime
- 1986-09-22 AU AU63013/86A patent/AU590798B2/en not_active Ceased
- 1986-10-01 JP JP61231356A patent/JPS6391381A/ja active Pending
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