IL72187A - Dihydrobenzopyran derivatives,their manufacture and pharmaceutical compositions containing them - Google Patents
Dihydrobenzopyran derivatives,their manufacture and pharmaceutical compositions containing themInfo
- Publication number
- IL72187A IL72187A IL72187A IL7218784A IL72187A IL 72187 A IL72187 A IL 72187A IL 72187 A IL72187 A IL 72187A IL 7218784 A IL7218784 A IL 7218784A IL 72187 A IL72187 A IL 72187A
- Authority
- IL
- Israel
- Prior art keywords
- hydrogen
- formula
- lower alkyl
- manufacture
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Feeding And Controlling Fuel (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Discharging, Photosensitive Material Shape In Electrophotography (AREA)
- Transformer Cooling (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50738383A | 1983-06-24 | 1983-06-24 | |
| US67419385A | 1985-01-18 | 1985-01-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL72187A0 IL72187A0 (en) | 1984-10-31 |
| IL72187A true IL72187A (en) | 1990-02-09 |
Family
ID=37102508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL72187A IL72187A (en) | 1983-06-24 | 1984-06-21 | Dihydrobenzopyran derivatives,their manufacture and pharmaceutical compositions containing them |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4650812A (pt) |
| EP (2) | EP0129906B1 (pt) |
| JP (2) | JPS6019782A (pt) |
| KR (1) | KR920001776B1 (pt) |
| AT (1) | ATE34981T1 (pt) |
| AU (2) | AU565490B2 (pt) |
| BR (1) | BR8403068A (pt) |
| CS (1) | CS246085B2 (pt) |
| DE (1) | DE3471933D1 (pt) |
| DK (1) | DK304784A (pt) |
| ES (2) | ES533678A0 (pt) |
| FI (1) | FI87207C (pt) |
| GR (1) | GR82135B (pt) |
| HU (1) | HU202512B (pt) |
| IL (1) | IL72187A (pt) |
| MC (1) | MC1596A1 (pt) |
| NO (1) | NO168643C (pt) |
| NZ (1) | NZ208610A (pt) |
| PH (1) | PH20806A (pt) |
| PT (1) | PT78779A (pt) |
| ZA (1) | ZA844519B (pt) |
| ZW (1) | ZW9884A1 (pt) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU548450B2 (en) * | 1983-08-08 | 1985-12-12 | G.D. Searle & Co. | Substituted dihydrobenzopyrans |
| US4565882A (en) * | 1984-01-06 | 1986-01-21 | G. D. Searle & Co. | Substituted dihydrobenzopyran-2-carboxylates |
| US4885309A (en) * | 1986-08-01 | 1989-12-05 | Hoffmann-La Roche Inc. | Therapeutic treatment of leukotriene-mediated dermal inflammation by topical administration of 3,4-dihydro-2H-1-benzopyran derivatives |
| ZA875319B (en) * | 1986-08-15 | 1988-02-15 | F. Hoffmann-La Roche & Co. Aktiengesellschaft | Use of dihydro benzopyran derivatives |
| US4874777A (en) * | 1987-04-10 | 1989-10-17 | Eli Lilly And Company | Leukotriene antagonists |
| US4853398A (en) * | 1987-04-13 | 1989-08-01 | Eli Lilly And Company | Leukotriene antagonists and use thereas |
| US4889871A (en) * | 1987-05-29 | 1989-12-26 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives |
| AT392902B (de) * | 1987-10-08 | 1991-07-10 | Hoffmann La Roche | Pharmazeutische verwendung von phenoxypentyloxy-3,4-dihydro-2h-1-benzopyran- derivaten |
| US5037747A (en) * | 1988-01-26 | 1991-08-06 | Hoffmann-La Roche Inc. | Production of benzopyran-2-carboxylic acids and esters by enzymatic hydrolysis |
| EP0336068A1 (en) * | 1988-02-11 | 1989-10-11 | F. Hoffmann-La Roche Ag | Phenoxyalkoxy-3,4-dihydro-2H-1-benzopyran derivatives |
| US5219883A (en) * | 1988-05-20 | 1993-06-15 | G. D. Searle & Co. | 2,2-di-substituted benzopyran leukotriene-D4 antagonists |
| US4950684A (en) * | 1988-05-20 | 1990-08-21 | G. D. Searle & Co. | 2,2-di-substituted benzopyran leukotriene-D4 antagonists |
| US5093353A (en) * | 1988-05-20 | 1992-03-03 | G. D. Searle & Co. | 2,2-di-substituted benzopyran leukotriene-D4 antagonists |
| US4931574A (en) * | 1988-08-23 | 1990-06-05 | Hoffmann-La Roche Inc. | Process for the preparation of benzopyrans |
| JPH0366669A (ja) * | 1989-08-03 | 1991-03-22 | Shionogi & Co Ltd | 複素環式化合物 |
| US5192782A (en) * | 1990-05-10 | 1993-03-09 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof |
| US5073562A (en) * | 1990-05-10 | 1991-12-17 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof |
| US5212198A (en) * | 1990-05-10 | 1993-05-18 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof |
| US5124350A (en) * | 1990-06-28 | 1992-06-23 | G. D. Searle & Co. | Leukotriene b4 antagonists |
| US5273999A (en) * | 1991-09-10 | 1993-12-28 | Hoffmann-La Roche Inc. | Carboxylic acid leukotriene B4 antagonists |
| PH30449A (en) * | 1991-11-25 | 1997-05-28 | Lilly Co Eli | Substituted phenyl phenol leukotriene antagonists |
| US5380740A (en) * | 1993-04-28 | 1995-01-10 | G. D. Searle & Co. | Anti-inflammatory compounds, compositions and method of use thereof |
| US5527827A (en) * | 1994-10-27 | 1996-06-18 | Merck Frosst Canada, Inc. | Bisarylcarbinol cinnamic acids as inhibitors of leukotriene biosynthesis |
| US6051586A (en) * | 1997-12-19 | 2000-04-18 | Bayer Corporation | Sulfonamide substituted chroman derivatives useful as beta 3 adrenoreceptor agonists |
| US6469031B1 (en) | 1998-12-18 | 2002-10-22 | Bayer Corporation | Carboxyl substituted chroman derivatives useful as beta 3 adrenoreceptor agonists |
| AU9287401A (en) | 2000-09-27 | 2002-04-08 | Merck & Co Inc | Benzopyrancarboxylic acid derivatives for the treatment of diabetes and lipid disorders |
| CA2427610A1 (en) | 2000-10-31 | 2002-08-08 | Merck & Co., Inc. | Benzopyrancarboxylic acid derivatives for the treatment of diabetes and lipid disorders |
| AR035605A1 (es) | 2000-12-11 | 2004-06-16 | Bayer Corp | Derivados de aminometil cromano di-sustituidos, un metodo para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la manufactura de medicamentos utiles como agonistas beta-3-adreno-receptores |
| AR035858A1 (es) | 2001-04-23 | 2004-07-21 | Bayer Corp | Derivados de cromano 2,6-sustituidos,composiciones farmaceuticas,uso de dichos derivados para la manufactura de medicamentos utiles como agonistas adrenorreceptores beta-3 |
| MXPA04001785A (es) | 2001-09-14 | 2004-07-08 | Bayer Ag | Benzofurano y derivados de dihidrobenzofurano utiles como agonistas de beta-3 adrenoreceptores. |
| KR101233223B1 (ko) * | 2004-12-21 | 2013-02-14 | 제이엔씨 석유 화학 주식회사 | 크로만환을 가지는 액정 화합물, 액정 조성물 및 이 액정조성물을 함유하는 액정 표시소자 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4133889A (en) * | 1971-07-29 | 1979-01-09 | Fisons, Ltd. | 2(5-Tetrazolyl)chromones |
| GB1384530A (en) * | 1971-07-29 | 1975-02-19 | Fisons Ltd | Chromone derivatives |
| SU469247A3 (ru) * | 1972-01-14 | 1975-04-30 | Майлз Лабораториз Инк (Фирма) | Способ получени производных хромона |
| ZA739471B (en) * | 1972-12-22 | 1974-08-28 | Hoffmann La Roche | Chromane derivatives |
| US4150050A (en) * | 1978-01-30 | 1979-04-17 | Hoffmann-La Roche Inc. | 3,6-Dioxo-1,4-cyclohexadien-1-yl-butandate esters |
| EP0061800B1 (en) * | 1981-03-24 | 1985-08-28 | FISONS plc | Anti srs-a carboxylic acid derivatives, processes for their production and pharmaceutical formulations containing them |
| ATE25251T1 (de) * | 1981-11-12 | 1987-02-15 | Fisons Plc | Anti srs-a carbonsaeure-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische formulierungen. |
| AU548450B2 (en) * | 1983-08-08 | 1985-12-12 | G.D. Searle & Co. | Substituted dihydrobenzopyrans |
| US4546194A (en) * | 1984-05-29 | 1985-10-08 | G. D. Searle & Co. | Substituted chromanon-2-yl alkanols and derivatives thereof |
-
1984
- 1984-06-14 ZA ZA844519A patent/ZA844519B/xx unknown
- 1984-06-20 FI FI842497A patent/FI87207C/fi not_active IP Right Cessation
- 1984-06-20 PT PT78779A patent/PT78779A/pt not_active IP Right Cessation
- 1984-06-21 DK DK304784A patent/DK304784A/da not_active Application Discontinuation
- 1984-06-21 NZ NZ208610A patent/NZ208610A/en unknown
- 1984-06-21 IL IL72187A patent/IL72187A/xx unknown
- 1984-06-22 NO NO84842549A patent/NO168643C/no unknown
- 1984-06-22 BR BR8403068A patent/BR8403068A/pt unknown
- 1984-06-22 HU HU842427A patent/HU202512B/hu not_active IP Right Cessation
- 1984-06-22 ZW ZW98/84A patent/ZW9884A1/xx unknown
- 1984-06-22 PH PH30874A patent/PH20806A/en unknown
- 1984-06-22 AU AU29785/84A patent/AU565490B2/en not_active Ceased
- 1984-06-22 MC MC841711A patent/MC1596A1/xx unknown
- 1984-06-22 GR GR75089A patent/GR82135B/el unknown
- 1984-06-22 CS CS844772A patent/CS246085B2/cs unknown
- 1984-06-23 ES ES533678A patent/ES533678A0/es active Granted
- 1984-06-23 JP JP59128475A patent/JPS6019782A/ja active Granted
- 1984-06-23 KR KR1019840003570A patent/KR920001776B1/ko not_active IP Right Cessation
- 1984-06-25 DE DE8484107289T patent/DE3471933D1/de not_active Expired
- 1984-06-25 AT AT84107289T patent/ATE34981T1/de active
- 1984-06-25 EP EP84107289A patent/EP0129906B1/de not_active Expired
-
1985
- 1985-01-18 US US06/692,479 patent/US4650812A/en not_active Expired - Fee Related
- 1985-03-29 ES ES541709A patent/ES541709A0/es active Granted
-
1986
- 1986-09-19 EP EP86112944A patent/EP0261254B1/en not_active Expired - Lifetime
- 1986-09-22 AU AU63013/86A patent/AU590798B2/en not_active Ceased
- 1986-10-01 JP JP61231356A patent/JPS6391381A/ja active Pending
Also Published As
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