NO168643C - Analogifremgangsmaate for fremstilling av terapeutisk aktive dihydrobenzopyranderivater. - Google Patents
Analogifremgangsmaate for fremstilling av terapeutisk aktive dihydrobenzopyranderivater.Info
- Publication number
- NO168643C NO168643C NO84842549A NO842549A NO168643C NO 168643 C NO168643 C NO 168643C NO 84842549 A NO84842549 A NO 84842549A NO 842549 A NO842549 A NO 842549A NO 168643 C NO168643 C NO 168643C
- Authority
- NO
- Norway
- Prior art keywords
- hydrogen
- formula
- dihydrobenzopyrand
- derivatives
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Feeding And Controlling Fuel (AREA)
- Discharging, Photosensitive Material Shape In Electrophotography (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Transformer Cooling (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50738383A | 1983-06-24 | 1983-06-24 | |
| US67419385A | 1985-01-18 | 1985-01-18 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO842549L NO842549L (no) | 1984-12-27 |
| NO168643B NO168643B (no) | 1991-12-09 |
| NO168643C true NO168643C (no) | 1992-03-18 |
Family
ID=37102508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO84842549A NO168643C (no) | 1983-06-24 | 1984-06-22 | Analogifremgangsmaate for fremstilling av terapeutisk aktive dihydrobenzopyranderivater. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4650812A (no) |
| EP (2) | EP0129906B1 (no) |
| JP (2) | JPS6019782A (no) |
| KR (1) | KR920001776B1 (no) |
| AT (1) | ATE34981T1 (no) |
| AU (2) | AU565490B2 (no) |
| BR (1) | BR8403068A (no) |
| CS (1) | CS246085B2 (no) |
| DE (1) | DE3471933D1 (no) |
| DK (1) | DK304784A (no) |
| ES (2) | ES533678A0 (no) |
| FI (1) | FI87207C (no) |
| GR (1) | GR82135B (no) |
| HU (1) | HU202512B (no) |
| IL (1) | IL72187A (no) |
| MC (1) | MC1596A1 (no) |
| NO (1) | NO168643C (no) |
| NZ (1) | NZ208610A (no) |
| PH (1) | PH20806A (no) |
| PT (1) | PT78779A (no) |
| ZA (1) | ZA844519B (no) |
| ZW (1) | ZW9884A1 (no) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU548450B2 (en) * | 1983-08-08 | 1985-12-12 | G.D. Searle & Co. | Substituted dihydrobenzopyrans |
| US4565882A (en) * | 1984-01-06 | 1986-01-21 | G. D. Searle & Co. | Substituted dihydrobenzopyran-2-carboxylates |
| US4885309A (en) * | 1986-08-01 | 1989-12-05 | Hoffmann-La Roche Inc. | Therapeutic treatment of leukotriene-mediated dermal inflammation by topical administration of 3,4-dihydro-2H-1-benzopyran derivatives |
| ZA875319B (en) * | 1986-08-15 | 1988-02-15 | F. Hoffmann-La Roche & Co. Aktiengesellschaft | Use of dihydro benzopyran derivatives |
| US4874777A (en) * | 1987-04-10 | 1989-10-17 | Eli Lilly And Company | Leukotriene antagonists |
| US4853398A (en) * | 1987-04-13 | 1989-08-01 | Eli Lilly And Company | Leukotriene antagonists and use thereas |
| US4889871A (en) * | 1987-05-29 | 1989-12-26 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives |
| AT392902B (de) * | 1987-10-08 | 1991-07-10 | Hoffmann La Roche | Pharmazeutische verwendung von phenoxypentyloxy-3,4-dihydro-2h-1-benzopyran- derivaten |
| US5037747A (en) * | 1988-01-26 | 1991-08-06 | Hoffmann-La Roche Inc. | Production of benzopyran-2-carboxylic acids and esters by enzymatic hydrolysis |
| EP0336068A1 (en) * | 1988-02-11 | 1989-10-11 | F. Hoffmann-La Roche Ag | Phenoxyalkoxy-3,4-dihydro-2H-1-benzopyran derivatives |
| US5219883A (en) * | 1988-05-20 | 1993-06-15 | G. D. Searle & Co. | 2,2-di-substituted benzopyran leukotriene-D4 antagonists |
| US4950684A (en) * | 1988-05-20 | 1990-08-21 | G. D. Searle & Co. | 2,2-di-substituted benzopyran leukotriene-D4 antagonists |
| US5093353A (en) * | 1988-05-20 | 1992-03-03 | G. D. Searle & Co. | 2,2-di-substituted benzopyran leukotriene-D4 antagonists |
| US4931574A (en) * | 1988-08-23 | 1990-06-05 | Hoffmann-La Roche Inc. | Process for the preparation of benzopyrans |
| JPH0366669A (ja) * | 1989-08-03 | 1991-03-22 | Shionogi & Co Ltd | 複素環式化合物 |
| US5073562A (en) * | 1990-05-10 | 1991-12-17 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof |
| US5192782A (en) * | 1990-05-10 | 1993-03-09 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof |
| US5212198A (en) * | 1990-05-10 | 1993-05-18 | G. D. Searle & Co. | Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof |
| US5124350A (en) * | 1990-06-28 | 1992-06-23 | G. D. Searle & Co. | Leukotriene b4 antagonists |
| US5273999A (en) * | 1991-09-10 | 1993-12-28 | Hoffmann-La Roche Inc. | Carboxylic acid leukotriene B4 antagonists |
| PH30449A (en) * | 1991-11-25 | 1997-05-28 | Lilly Co Eli | Substituted phenyl phenol leukotriene antagonists |
| US5380740A (en) * | 1993-04-28 | 1995-01-10 | G. D. Searle & Co. | Anti-inflammatory compounds, compositions and method of use thereof |
| US5527827A (en) * | 1994-10-27 | 1996-06-18 | Merck Frosst Canada, Inc. | Bisarylcarbinol cinnamic acids as inhibitors of leukotriene biosynthesis |
| US6469031B1 (en) | 1998-12-18 | 2002-10-22 | Bayer Corporation | Carboxyl substituted chroman derivatives useful as beta 3 adrenoreceptor agonists |
| US6051586A (en) * | 1997-12-19 | 2000-04-18 | Bayer Corporation | Sulfonamide substituted chroman derivatives useful as beta 3 adrenoreceptor agonists |
| AU9287401A (en) | 2000-09-27 | 2002-04-08 | Merck & Co Inc | Benzopyrancarboxylic acid derivatives for the treatment of diabetes and lipid disorders |
| AU2002248221B2 (en) | 2000-10-31 | 2006-08-17 | Merck & Co., Inc. | Benzopyrancarboxylic acid derivatives for the treatment of diabetes and lipid disorders |
| AR035605A1 (es) | 2000-12-11 | 2004-06-16 | Bayer Corp | Derivados de aminometil cromano di-sustituidos, un metodo para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la manufactura de medicamentos utiles como agonistas beta-3-adreno-receptores |
| AR035858A1 (es) | 2001-04-23 | 2004-07-21 | Bayer Corp | Derivados de cromano 2,6-sustituidos,composiciones farmaceuticas,uso de dichos derivados para la manufactura de medicamentos utiles como agonistas adrenorreceptores beta-3 |
| JP2005526696A (ja) | 2001-09-14 | 2005-09-08 | バイエル・フアーマシユーチカルズ・コーポレーシヨン | ベータ−３アドレナリン受容体アゴニストとして有用なベンゾフランおよびジヒドロベンゾフラン誘導体 |
| KR101233223B1 (ko) * | 2004-12-21 | 2013-02-14 | 제이엔씨 석유 화학 주식회사 | 크로만환을 가지는 액정 화합물, 액정 조성물 및 이 액정조성물을 함유하는 액정 표시소자 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1384530A (en) * | 1971-07-29 | 1975-02-19 | Fisons Ltd | Chromone derivatives |
| US4133889A (en) * | 1971-07-29 | 1979-01-09 | Fisons, Ltd. | 2(5-Tetrazolyl)chromones |
| SU469247A3 (ru) * | 1972-01-14 | 1975-04-30 | Майлз Лабораториз Инк (Фирма) | Способ получени производных хромона |
| ZA739471B (en) * | 1972-12-22 | 1974-08-28 | Hoffmann La Roche | Chromane derivatives |
| US4150050A (en) * | 1978-01-30 | 1979-04-17 | Hoffmann-La Roche Inc. | 3,6-Dioxo-1,4-cyclohexadien-1-yl-butandate esters |
| DE3265715D1 (en) * | 1981-03-24 | 1985-10-03 | Fisons Plc | Anti srs-a carboxylic acid derivatives, processes for their production and pharmaceutical formulations containing them |
| DE3275295D1 (en) * | 1981-11-12 | 1987-03-05 | Fisons Plc | Anti-srs-a carboxylic acid derivatives, processes for their production, and pharmaceutical formulation containing them |
| AU548450B2 (en) * | 1983-08-08 | 1985-12-12 | G.D. Searle & Co. | Substituted dihydrobenzopyrans |
| US4546194A (en) * | 1984-05-29 | 1985-10-08 | G. D. Searle & Co. | Substituted chromanon-2-yl alkanols and derivatives thereof |
-
1984
- 1984-06-14 ZA ZA844519A patent/ZA844519B/xx unknown
- 1984-06-20 FI FI842497A patent/FI87207C/fi not_active IP Right Cessation
- 1984-06-20 PT PT78779A patent/PT78779A/pt not_active IP Right Cessation
- 1984-06-21 IL IL72187A patent/IL72187A/xx unknown
- 1984-06-21 DK DK304784A patent/DK304784A/da not_active Application Discontinuation
- 1984-06-21 NZ NZ208610A patent/NZ208610A/en unknown
- 1984-06-22 PH PH30874A patent/PH20806A/en unknown
- 1984-06-22 NO NO84842549A patent/NO168643C/no unknown
- 1984-06-22 HU HU842427A patent/HU202512B/hu not_active IP Right Cessation
- 1984-06-22 BR BR8403068A patent/BR8403068A/pt unknown
- 1984-06-22 MC MC841711A patent/MC1596A1/xx unknown
- 1984-06-22 GR GR75089A patent/GR82135B/el unknown
- 1984-06-22 AU AU29785/84A patent/AU565490B2/en not_active Ceased
- 1984-06-22 CS CS844772A patent/CS246085B2/cs unknown
- 1984-06-22 ZW ZW98/84A patent/ZW9884A1/xx unknown
- 1984-06-23 JP JP59128475A patent/JPS6019782A/ja active Granted
- 1984-06-23 ES ES533678A patent/ES533678A0/es active Granted
- 1984-06-23 KR KR1019840003570A patent/KR920001776B1/ko not_active IP Right Cessation
- 1984-06-25 DE DE8484107289T patent/DE3471933D1/de not_active Expired
- 1984-06-25 EP EP84107289A patent/EP0129906B1/de not_active Expired
- 1984-06-25 AT AT84107289T patent/ATE34981T1/de active
-
1985
- 1985-01-18 US US06/692,479 patent/US4650812A/en not_active Expired - Fee Related
- 1985-03-29 ES ES541709A patent/ES8602741A1/es not_active Expired
-
1986
- 1986-09-19 EP EP86112944A patent/EP0261254B1/en not_active Expired - Lifetime
- 1986-09-22 AU AU63013/86A patent/AU590798B2/en not_active Ceased
- 1986-10-01 JP JP61231356A patent/JPS6391381A/ja active Pending
Also Published As
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