BR112023018844A2 - Composições e métodos para geração de células t gama-delta de células-tronco pluripotentes induzidas - Google Patents

Composições e métodos para geração de células t gama-delta de células-tronco pluripotentes induzidas

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Publication number
BR112023018844A2
BR112023018844A2 BR112023018844A BR112023018844A BR112023018844A2 BR 112023018844 A2 BR112023018844 A2 BR 112023018844A2 BR 112023018844 A BR112023018844 A BR 112023018844A BR 112023018844 A BR112023018844 A BR 112023018844A BR 112023018844 A2 BR112023018844 A2 BR 112023018844A2
Authority
BR
Brazil
Prior art keywords
cells
methods
pluripotent stem
induced pluripotent
delta
Prior art date
Application number
BR112023018844A
Other languages
English (en)
Portuguese (pt)
Inventor
Andriana Lebid
Barry Morse
Brenda Salantes
Buddha Gurung
Del Casale Christina
Katherine Santostefano
Lucas Thompson
Luis Borges
Marilda Beqiri
Mark Mendonca
Mark Wallet
Francis Naso Michael
Toshinobu Nishimura
Zengrong Zhu
Original Assignee
Century Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Century Therapeutics Inc filed Critical Century Therapeutics Inc
Publication of BR112023018844A2 publication Critical patent/BR112023018844A2/pt

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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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BR112023018844A 2021-04-07 2022-03-31 Composições e métodos para geração de células t gama-delta de células-tronco pluripotentes induzidas BR112023018844A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163171646P 2021-04-07 2021-04-07
US202163279837P 2021-11-16 2021-11-16
PCT/US2022/022793 WO2022216514A1 (en) 2021-04-07 2022-03-31 Compositions and methods for generating gamma-delta t cells from induced pluripotent stem cells

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BR112023018844A2 true BR112023018844A2 (pt) 2023-10-10

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BR112023018844A BR112023018844A2 (pt) 2021-04-07 2022-03-31 Composições e métodos para geração de células t gama-delta de células-tronco pluripotentes induzidas

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Country Link
US (2) US20220333073A1 (https=)
EP (1) EP4320227A1 (https=)
JP (1) JP2024519515A (https=)
KR (1) KR20230170703A (https=)
AU (1) AU2022252997A1 (https=)
BR (1) BR112023018844A2 (https=)
CA (1) CA3214045A1 (https=)
IL (1) IL307358A (https=)
MX (1) MX2023011927A (https=)
TW (1) TW202305113A (https=)
WO (1) WO2022216514A1 (https=)

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WO2024206992A2 (en) * 2023-03-30 2024-10-03 Yale University Universal antibody receptors, guar-t cells and therapeutic use thereof
WO2024254013A1 (en) * 2023-06-04 2024-12-12 Cytovia Therapeutics, Llc. Natural killer cells with novel il-15 knock-in and methods of use thereof
WO2025101938A2 (en) 2023-11-10 2025-05-15 Century Therapeutics, Inc. Genetically engineered cells having multi-transmembrane domain chimeric antigen receptors utilizing g protein-coupled receptor scaffolds, and uses thereof
WO2025106626A1 (en) 2023-11-15 2025-05-22 Century Therapeutics, Inc. Genetically engineered cells expressing c-x-c chemokine receptor type 4, and uses thereof
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