MX2023011927A - Composiciones y metodos para la generacion de linfocitos t gamma-delta a partir de celulas madre pluripotentes inducidas. - Google Patents

Composiciones y metodos para la generacion de linfocitos t gamma-delta a partir de celulas madre pluripotentes inducidas.

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Publication number
MX2023011927A
MX2023011927A MX2023011927A MX2023011927A MX2023011927A MX 2023011927 A MX2023011927 A MX 2023011927A MX 2023011927 A MX2023011927 A MX 2023011927A MX 2023011927 A MX2023011927 A MX 2023011927A MX 2023011927 A MX2023011927 A MX 2023011927A
Authority
MX
Mexico
Prior art keywords
lymphocytes
methods
generation
stem cells
pluripotent stem
Prior art date
Application number
MX2023011927A
Other languages
English (en)
Spanish (es)
Inventor
Mark Mendonca
Luis Borges
Mark Wallet
Barry Morse
Buddha Gurung
Lucas Thompson
Toshinobu Nishimura
Andriana Lebid
Brenda Salantes
Katherine Santostefano
Michael Francis Naso
Zengrong Zhu
Casale Christina Del
Marilda Beqiri
Original Assignee
Century Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Century Therapeutics Inc filed Critical Century Therapeutics Inc
Publication of MX2023011927A publication Critical patent/MX2023011927A/es

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32—T-cell receptors [TCR]
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    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/421—Immunoglobulin superfamily
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MX2023011927A 2021-04-07 2022-03-31 Composiciones y metodos para la generacion de linfocitos t gamma-delta a partir de celulas madre pluripotentes inducidas. MX2023011927A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163171646P 2021-04-07 2021-04-07
US202163279837P 2021-11-16 2021-11-16
PCT/US2022/022793 WO2022216514A1 (en) 2021-04-07 2022-03-31 Compositions and methods for generating gamma-delta t cells from induced pluripotent stem cells

Publications (1)

Publication Number Publication Date
MX2023011927A true MX2023011927A (es) 2023-10-23

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MX2023011927A MX2023011927A (es) 2021-04-07 2022-03-31 Composiciones y metodos para la generacion de linfocitos t gamma-delta a partir de celulas madre pluripotentes inducidas.

Country Status (11)

Country Link
US (2) US20220333073A1 (https=)
EP (1) EP4320227A1 (https=)
JP (1) JP2024519515A (https=)
KR (1) KR20230170703A (https=)
AU (1) AU2022252997A1 (https=)
BR (1) BR112023018844A2 (https=)
CA (1) CA3214045A1 (https=)
IL (1) IL307358A (https=)
MX (1) MX2023011927A (https=)
TW (1) TW202305113A (https=)
WO (1) WO2022216514A1 (https=)

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WO2024191989A1 (en) * 2023-03-14 2024-09-19 Shattuck Labs, Inc. Treatment of b cell-mediated diseases by activating cd20-targeted gamma delta t cells
WO2024206992A2 (en) * 2023-03-30 2024-10-03 Yale University Universal antibody receptors, guar-t cells and therapeutic use thereof
WO2024254013A1 (en) * 2023-06-04 2024-12-12 Cytovia Therapeutics, Llc. Natural killer cells with novel il-15 knock-in and methods of use thereof
WO2025101938A2 (en) 2023-11-10 2025-05-15 Century Therapeutics, Inc. Genetically engineered cells having multi-transmembrane domain chimeric antigen receptors utilizing g protein-coupled receptor scaffolds, and uses thereof
WO2025106626A1 (en) 2023-11-15 2025-05-22 Century Therapeutics, Inc. Genetically engineered cells expressing c-x-c chemokine receptor type 4, and uses thereof
CN118845737A (zh) * 2024-07-08 2024-10-29 海南大学 托瑞米芬在增强γδT细胞抗肿瘤功能中的应用

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