BR112023000798A2 - Composições farmacêuticas compreendendo venglustat - Google Patents
Composições farmacêuticas compreendendo venglustatInfo
- Publication number
- BR112023000798A2 BR112023000798A2 BR112023000798A BR112023000798A BR112023000798A2 BR 112023000798 A2 BR112023000798 A2 BR 112023000798A2 BR 112023000798 A BR112023000798 A BR 112023000798A BR 112023000798 A BR112023000798 A BR 112023000798A BR 112023000798 A2 BR112023000798 A2 BR 112023000798A2
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical compositions
- venglutat
- venglustat
- capsules
- diluent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4833—Encapsulating processes; Filling of capsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063056075P | 2020-07-24 | 2020-07-24 | |
| EP21152595 | 2021-01-20 | ||
| PCT/IB2021/056673 WO2022018695A1 (en) | 2020-07-24 | 2021-07-23 | Pharmaceutical compositions comprising venglustat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112023000798A2 true BR112023000798A2 (pt) | 2023-02-07 |
Family
ID=77021693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112023000798A BR112023000798A2 (pt) | 2020-07-24 | 2021-07-23 | Composições farmacêuticas compreendendo venglustat |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11857512B2 (https=) |
| EP (1) | EP4185267A1 (https=) |
| JP (1) | JP2023534322A (https=) |
| KR (1) | KR20230043024A (https=) |
| CN (1) | CN116133647A (https=) |
| AU (1) | AU2021311131B2 (https=) |
| BR (1) | BR112023000798A2 (https=) |
| CA (1) | CA3186766A1 (https=) |
| CO (1) | CO2023000523A2 (https=) |
| IL (1) | IL300090A (https=) |
| MX (1) | MX2023001014A (https=) |
| TW (1) | TW202220648A (https=) |
| WO (1) | WO2022018695A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114040762A (zh) | 2019-02-04 | 2022-02-11 | 建新公司 | 使用葡糖神经酰胺合酶(gcs)的抑制剂治疗纤毛疾病 |
| JP2025541739A (ja) | 2022-12-01 | 2025-12-23 | ジェンザイム・コーポレーション | Ｃｙｐ３ａ４の強力な又は中程度の阻害剤と組み合わせたベングルスタット |
| WO2025219952A1 (en) | 2024-04-19 | 2025-10-23 | Genzyme Corporation | Venglustat for use in methods for reducing disease related biomarker levels in patients with ganglioside storage disorders |
| WO2025219951A1 (en) | 2024-04-19 | 2025-10-23 | Genzyme Corporation | Venglustat for use in methods for reducing disease related biomarker levels in patients with ganglioside storage disorders |
| WO2025262570A1 (en) | 2024-06-17 | 2025-12-26 | Genzyme Corporation | Venglustat as an inhibitor of glucosylceramide synthase in subjects having hepatic impairment |
| EP4702971A1 (en) * | 2024-09-03 | 2026-03-04 | Athena Pharmaceutiques SAS | Method for preparation of lisdexamfetamine dimesylate dispersible tablet |
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| NL130759C (https=) | 1965-10-07 | |||
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| CN114040762A (zh) | 2019-02-04 | 2022-02-11 | 建新公司 | 使用葡糖神经酰胺合酶(gcs)的抑制剂治疗纤毛疾病 |
| CN113645969A (zh) | 2019-02-04 | 2021-11-12 | 建新公司 | 用于治疗与溶酶体贮积症相关的症状和病症的方法 |
| WO2021061701A1 (en) * | 2019-09-25 | 2021-04-01 | Teva Pharmaceuticals International Gmbh | Solid state forms of lucerastat salts and process for preparation thereof |
| JP2023512366A (ja) | 2020-02-03 | 2023-03-27 | ジェンザイム・コーポレーション | リソソーム蓄積性疾患と関連する神経学的症状を処置するための方法 |
-
2021
- 2021-07-23 AU AU2021311131A patent/AU2021311131B2/en active Active
- 2021-07-23 CA CA3186766A patent/CA3186766A1/en active Pending
- 2021-07-23 TW TW110127154A patent/TW202220648A/zh unknown
- 2021-07-23 IL IL300090A patent/IL300090A/en unknown
- 2021-07-23 MX MX2023001014A patent/MX2023001014A/es unknown
- 2021-07-23 US US17/384,083 patent/US11857512B2/en active Active
- 2021-07-23 JP JP2021564954A patent/JP2023534322A/ja active Pending
- 2021-07-23 KR KR1020217038775A patent/KR20230043024A/ko active Pending
- 2021-07-23 CN CN202180059425.8A patent/CN116133647A/zh active Pending
- 2021-07-23 WO PCT/IB2021/056673 patent/WO2022018695A1/en not_active Ceased
- 2021-07-23 BR BR112023000798A patent/BR112023000798A2/pt unknown
- 2021-07-23 EP EP21745451.1A patent/EP4185267A1/en active Pending
-
2023
- 2023-01-17 CO CONC2023/0000523A patent/CO2023000523A2/es unknown
- 2023-11-21 US US18/515,897 patent/US20240091208A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX2023001014A (es) | 2023-03-01 |
| AU2021311131B2 (en) | 2026-02-19 |
| CN116133647A (zh) | 2023-05-16 |
| WO2022018695A1 (en) | 2022-01-27 |
| CO2023000523A2 (es) | 2023-01-26 |
| US11857512B2 (en) | 2024-01-02 |
| KR20230043024A (ko) | 2023-03-30 |
| CA3186766A1 (en) | 2022-01-27 |
| AU2021311131A1 (en) | 2023-03-23 |
| EP4185267A1 (en) | 2023-05-31 |
| US20220023272A1 (en) | 2022-01-27 |
| TW202220648A (zh) | 2022-06-01 |
| IL300090A (en) | 2023-03-01 |
| JP2023534322A (ja) | 2023-08-09 |
| US20240091208A1 (en) | 2024-03-21 |
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