BR112022026161A2 - Compostos de piperidina substituídos e seu uso - Google Patents
Compostos de piperidina substituídos e seu usoInfo
- Publication number
- BR112022026161A2 BR112022026161A2 BR112022026161A BR112022026161A BR112022026161A2 BR 112022026161 A2 BR112022026161 A2 BR 112022026161A2 BR 112022026161 A BR112022026161 A BR 112022026161A BR 112022026161 A BR112022026161 A BR 112022026161A BR 112022026161 A2 BR112022026161 A2 BR 112022026161A2
- Authority
- BR
- Brazil
- Prior art keywords
- substituted piperidine
- piperidine compounds
- compounds
- iii
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pain & Pain Management (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2020122864 | 2020-07-17 | ||
| PCT/JP2021/026649 WO2022014680A1 (ja) | 2020-07-17 | 2021-07-15 | 置換ピペリジン化合物及びその用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022026161A2 true BR112022026161A2 (pt) | 2023-01-31 |
Family
ID=79291962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022026161A BR112022026161A2 (pt) | 2020-07-17 | 2021-07-15 | Compostos de piperidina substituídos e seu uso |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US11479552B2 (enExample) |
| EP (1) | EP4151277A4 (enExample) |
| JP (1) | JP7190612B2 (enExample) |
| KR (1) | KR20230040953A (enExample) |
| CN (3) | CN119258067A (enExample) |
| AR (1) | AR122973A1 (enExample) |
| AU (1) | AU2021308053A1 (enExample) |
| BR (1) | BR112022026161A2 (enExample) |
| CA (1) | CA3187835A1 (enExample) |
| CL (1) | CL2022003666A1 (enExample) |
| CO (1) | CO2022018446A2 (enExample) |
| IL (1) | IL299125B1 (enExample) |
| MX (1) | MX2022016388A (enExample) |
| PE (1) | PE20231103A1 (enExample) |
| PH (1) | PH12022553488A1 (enExample) |
| TW (1) | TWI888599B (enExample) |
| UA (1) | UA129636C2 (enExample) |
| WO (1) | WO2022014680A1 (enExample) |
| ZA (1) | ZA202213562B (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4065585B1 (en) | 2019-11-25 | 2025-08-20 | Alkermes, Inc. | Substituted macrocyclic compounds and related methods of treatment |
| US11760747B2 (en) | 2020-12-21 | 2023-09-19 | Alkermes, Inc. | Substituted piperidino compounds and related methods of treatment |
| US12006330B2 (en) | 2020-12-21 | 2024-06-11 | Alkermes, Inc. | Substituted macrocyclic compounds and related methods of treatment |
| WO2023136279A1 (ja) * | 2022-01-14 | 2023-07-20 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 置換ピペリジン化合物の結晶並びに置換ピペリジン化合物の塩及びそれらの結晶 |
| JP7591592B2 (ja) * | 2022-01-14 | 2024-11-28 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 置換ピペリジン化合物を含有する医薬 |
| IL319940A (en) * | 2022-10-07 | 2025-05-01 | Kissei Pharmaceutical | Cyclopentane compound |
| WO2024095158A1 (en) | 2022-10-31 | 2024-05-10 | Takeda Pharmaceutical Company Limited | Dosing of orexin type 2 receptor agonists |
| AU2023395547A1 (en) | 2022-12-16 | 2025-06-26 | Daiichi Sankyo Company, Limited | 2-azabicyclo[3.1.1]heptane compound |
| TW202502342A (zh) | 2023-06-02 | 2025-01-16 | 日商武田藥品工業股份有限公司 | 食慾素２受體促效劑用於改善睡眠期間之呼吸功能的用途 |
| WO2025124698A1 (en) | 2023-12-12 | 2025-06-19 | Idorsia Pharmaceuticals Ltd | Aryl sulfone and sulfanone derivatives as orexin receptor modulators |
| WO2025132542A1 (en) | 2023-12-19 | 2025-06-26 | Idorsia Pharmaceuticals Ltd | Macrocyclic orexin agonists |
| WO2025137359A1 (en) | 2023-12-20 | 2025-06-26 | Eisai R&D Management Co., Ltd. | Assay methods to identify a disease |
| WO2025229493A1 (en) | 2024-04-29 | 2025-11-06 | Takeda Pharmaceutical Company Limited | Dosing of orexin type 2 receptor agonists |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG34208A1 (en) | 1995-03-01 | 1996-12-06 | Guy Andrew Vaz | Blast and fragment resistant polyurethane boot sole for safety footwear |
| CA2220036A1 (en) | 1995-05-05 | 1996-11-07 | Human Genome Sciences, Inc. | Human neuropeptide receptor |
| US6309854B1 (en) | 1996-12-17 | 2001-10-30 | Smithkline Beecham Corporation | Polynucleotides encoding ligands of the neuropeptide receptor HFGAN72 |
| US6159605A (en) | 1997-02-18 | 2000-12-12 | Dainichiseika Color & Chemicals Mfg. Co., Ltd. | Ink-jet recording sheet |
| US5935814A (en) | 1997-04-30 | 1999-08-10 | Smithkline Beecham Corporation | Polynucleotides encoding HFGAN72Y receptor |
| US6020157A (en) | 1997-04-30 | 2000-02-01 | Smithkline Beecham Corporation | Polynucleotides encoding HFGAN72X receptor |
| US6166193A (en) | 1997-07-25 | 2000-12-26 | Board Of Regents, University Of Texas System | Polynucleotides encoding MY1 receptor |
| KR100327888B1 (ko) | 1999-07-14 | 2002-03-09 | 정숭렬 | 도로포장 파손촉진 시험장치의 무선제어 시스템 |
| CA2551037A1 (en) | 2003-09-22 | 2005-03-31 | Banyu Pharmaceutical Co., Ltd. | Novel piperidine derivative |
| CN101035792B (zh) * | 2004-10-20 | 2010-09-15 | 神经研究公司 | 新颖的二氮杂双环芳基衍生物和它们的医药用途 |
| JP2009184924A (ja) | 2006-05-31 | 2009-08-20 | Eisai R & D Management Co Ltd | 生物学的試薬用化合物 |
| TW201444849A (zh) | 2013-03-13 | 2014-12-01 | Janssen Pharmaceutica Nv | 經取代的7-氮雜雙環類及其作為食慾激素受體調節劑之用途 |
-
2021
- 2021-07-15 TW TW110126031A patent/TWI888599B/zh active
- 2021-07-15 CN CN202411462171.6A patent/CN119258067A/zh active Pending
- 2021-07-15 EP EP21842047.9A patent/EP4151277A4/en active Pending
- 2021-07-15 WO PCT/JP2021/026649 patent/WO2022014680A1/ja not_active Ceased
- 2021-07-15 CN CN202411459551.4A patent/CN119235864A/zh active Pending
- 2021-07-15 US US17/376,452 patent/US11479552B2/en active Active
- 2021-07-15 CA CA3187835A patent/CA3187835A1/en active Pending
- 2021-07-15 MX MX2022016388A patent/MX2022016388A/es unknown
- 2021-07-15 KR KR1020227044679A patent/KR20230040953A/ko active Pending
- 2021-07-15 BR BR112022026161A patent/BR112022026161A2/pt unknown
- 2021-07-15 CN CN202180044081.3A patent/CN115884971B/zh active Active
- 2021-07-15 UA UAA202204882A patent/UA129636C2/uk unknown
- 2021-07-15 PE PE2022003006A patent/PE20231103A1/es unknown
- 2021-07-15 PH PH1/2022/553488A patent/PH12022553488A1/en unknown
- 2021-07-15 AU AU2021308053A patent/AU2021308053A1/en active Pending
- 2021-07-15 JP JP2022536446A patent/JP7190612B2/ja active Active
- 2021-07-15 AR ARP210101982A patent/AR122973A1/es unknown
-
2022
- 2022-12-14 IL IL299125A patent/IL299125B1/en unknown
- 2022-12-14 ZA ZA2022/13562A patent/ZA202213562B/en unknown
- 2022-12-20 CL CL2022003666A patent/CL2022003666A1/es unknown
- 2022-12-20 CO CONC2022/0018446A patent/CO2022018446A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CO2022018446A2 (es) | 2023-03-07 |
| UA129636C2 (uk) | 2025-06-18 |
| CN115884971B (zh) | 2024-11-05 |
| CL2022003666A1 (es) | 2023-05-26 |
| PE20231103A1 (es) | 2023-07-19 |
| ZA202213562B (en) | 2023-10-25 |
| US20220017517A1 (en) | 2022-01-20 |
| WO2022014680A1 (ja) | 2022-01-20 |
| IL299125B1 (en) | 2025-11-01 |
| IL299125A (en) | 2023-02-01 |
| TW202216705A (zh) | 2022-05-01 |
| CN119258067A (zh) | 2025-01-07 |
| AR122973A1 (es) | 2022-10-19 |
| JPWO2022014680A1 (enExample) | 2022-01-20 |
| KR20230040953A (ko) | 2023-03-23 |
| PH12022553488A1 (en) | 2024-04-22 |
| JP7190612B2 (ja) | 2022-12-15 |
| US11479552B2 (en) | 2022-10-25 |
| CA3187835A1 (en) | 2022-01-20 |
| TWI888599B (zh) | 2025-07-01 |
| CN115884971A (zh) | 2023-03-31 |
| AU2021308053A1 (en) | 2023-02-02 |
| MX2022016388A (es) | 2023-01-30 |
| EP4151277A4 (en) | 2024-06-26 |
| CN119235864A (zh) | 2025-01-03 |
| EP4151277A1 (en) | 2023-03-22 |
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