BR112022016020A2 - Neoantígenos expressos em câncer de ovário e seus usos - Google Patents

Neoantígenos expressos em câncer de ovário e seus usos

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Publication number
BR112022016020A2
BR112022016020A2 BR112022016020A BR112022016020A BR112022016020A2 BR 112022016020 A2 BR112022016020 A2 BR 112022016020A2 BR 112022016020 A BR112022016020 A BR 112022016020A BR 112022016020 A BR112022016020 A BR 112022016020A BR 112022016020 A2 BR112022016020 A2 BR 112022016020A2
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BR
Brazil
Prior art keywords
ovarian cancer
neoantigens
expressed
neoantigens expressed
vaccines
Prior art date
Application number
BR112022016020A
Other languages
English (en)
Inventor
BHARGAVA Vipul
Krishna Vinod
J Pocalyko David
SAFABAKHSH Pegah
Alejandro Sepulveda Manuel
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of BR112022016020A2 publication Critical patent/BR112022016020A2/pt

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    • A61K39/0005—Vertebrate antigens
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
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    • A61P35/00—Antineoplastic agents
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/80—Vaccine for a specifically defined cancer
    • A61K2039/892—Reproductive system [uterus, ovaries, cervix, testes]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2710/10011—Adenoviridae
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    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24041—Use of virus, viral particle or viral elements as a vector

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  • Peptides Or Proteins (AREA)

Abstract

NEOANTÍGENOS EXPRESSOS EM CÂNCER DE OVÁRIO E SEUS USOS. A presente invenção refere-se a neoantígenos de câncer de ovário, polinucleotídeos que os codificam, vetores, células hospedeiras, partículas de vírus recombinantes, vacinas que compreendem os neoantígenos, moléculas proteináceas que se ligam aos neoantígenos de câncer de ovário e a métodos de preparo e uso dos mesmos.
BR112022016020A 2020-02-14 2021-02-12 Neoantígenos expressos em câncer de ovário e seus usos BR112022016020A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202062976384P 2020-02-14 2020-02-14
PCT/IB2021/051184 WO2021161244A1 (en) 2020-02-14 2021-02-12 Neoantigens expressed in ovarian cancer and their uses

Publications (1)

Publication Number Publication Date
BR112022016020A2 true BR112022016020A2 (pt) 2022-10-11

Family

ID=74669210

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022016020A BR112022016020A2 (pt) 2020-02-14 2021-02-12 Neoantígenos expressos em câncer de ovário e seus usos

Country Status (21)

Country Link
US (1) US11945881B2 (pt)
EP (1) EP4103222A1 (pt)
JP (1) JP2023514566A (pt)
KR (1) KR20220141848A (pt)
CN (1) CN115515623A (pt)
AR (1) AR121334A1 (pt)
AU (1) AU2021220007A1 (pt)
BR (1) BR112022016020A2 (pt)
CA (1) CA3172756A1 (pt)
CL (1) CL2022002187A1 (pt)
CO (1) CO2022012327A2 (pt)
CR (1) CR20220397A (pt)
DO (1) DOP2022000167A (pt)
EC (1) ECSP22071330A (pt)
IL (1) IL295546A (pt)
JO (1) JOP20220185A1 (pt)
MX (1) MX2022009986A (pt)
PE (1) PE20221510A1 (pt)
TW (1) TW202144388A (pt)
UY (1) UY39078A (pt)
WO (1) WO2021161244A1 (pt)

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