BR112022008115A2 - Processo para a produção de peptídeos de colágeno a partir de ossos e peptídeos de colágeno produzidos - Google Patents
Processo para a produção de peptídeos de colágeno a partir de ossos e peptídeos de colágeno produzidosInfo
- Publication number
- BR112022008115A2 BR112022008115A2 BR112022008115A BR112022008115A BR112022008115A2 BR 112022008115 A2 BR112022008115 A2 BR 112022008115A2 BR 112022008115 A BR112022008115 A BR 112022008115A BR 112022008115 A BR112022008115 A BR 112022008115A BR 112022008115 A2 BR112022008115 A2 BR 112022008115A2
- Authority
- BR
- Brazil
- Prior art keywords
- bones
- collagen peptides
- less
- minutes
- production
- Prior art date
Links
- 210000000988 bone and bone Anatomy 0.000 title abstract 10
- 102000008186 Collagen Human genes 0.000 title abstract 8
- 108010035532 Collagen Proteins 0.000 title abstract 8
- 229920001436 collagen Polymers 0.000 title abstract 8
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 8
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 238000000227 grinding Methods 0.000 abstract 2
- 102000035195 Peptidases Human genes 0.000 abstract 1
- 108091005804 Peptidases Proteins 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000007900 aqueous suspension Substances 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 238000002803 maceration Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 238000002791 soaking Methods 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/10—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from hair, feathers, horn, skins, leather, bones, or the like
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/04—Animal proteins
- A23J3/06—Gelatine
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
- A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
- A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
- A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
- A23J3/342—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of collagen; of gelatin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21062—Subtilisin (3.4.21.62)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PROCESSO PARA A PRODUÇÃO DE PEPTÍDEOS DE COLÁGENO A PARTIR DE OSSOS E PEPTÍDEOS DE COLÁGENO PRODUZIDOS. A presente invenção refere-se a um processo para a produção de peptídeos de colágeno a partir de ossos, que compreende as seguintes etapas: a) fornecimento de ossos de animais vertebrados; b) trituração mecânica dos ossos até um tamanho de partícula inferior a 1.000 µm, preferivelmente inferior a 500 µm, mais preferivelmente inferior a 300 µm, a uma temperatura inferior a 70°C durante a trituração; c) aquecimento dos ossos triturados em uma suspensão aquosa a uma temperatura acima de 100°C, preferivelmente acima de 120°C, mais preferivelmente acima de 130°C, por um período de 1 a 30 minutos, preferivelmente 2 a 10 minutos, mais preferivelmente 4 a 8 minutos; d) adição de uma ou mais proteases à suspensão, para obter uma solução aquosa de peptídeos de colágeno; e e) separação da solução aquosa de peptídeos de colágeno dos ossos triturados, sendo que o processo não compreende nem uma maceração dos ossos com um ácido, nem uma encalagem dos ossos com uma base e sendo que os ossos fornecidos na etapa a) não foram submetidos a qualquer encalagem. A invenção refere-se, além disso, aos peptídeos de colágeno, que são produzidos de acordo com este processo.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102019130196.3A DE102019130196A1 (de) | 2019-11-08 | 2019-11-08 | Verfahren zur Herstellung von Kollagenpeptiden aus Knochen, und hergestellte Kollagenpeptide |
| PCT/EP2020/077092 WO2021089243A1 (de) | 2019-11-08 | 2020-09-28 | Verfahren zur herstellung von kollagenpeptiden aus knochen, und hergestellte kollagenpeptide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022008115A2 true BR112022008115A2 (pt) | 2022-07-19 |
Family
ID=72717848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022008115A BR112022008115A2 (pt) | 2019-11-08 | 2020-09-28 | Processo para a produção de peptídeos de colágeno a partir de ossos e peptídeos de colágeno produzidos |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220256886A1 (pt) |
| EP (1) | EP4017272A1 (pt) |
| JP (1) | JP2023502010A (pt) |
| CN (1) | CN114845560A (pt) |
| AU (1) | AU2020378186A1 (pt) |
| BR (1) | BR112022008115A2 (pt) |
| DE (1) | DE102019130196A1 (pt) |
| MX (1) | MX2022005337A (pt) |
| WO (1) | WO2021089243A1 (pt) |
| ZA (1) | ZA202205099B (pt) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4176199A (en) * | 1978-05-15 | 1979-11-27 | Sugardale Foods, Incorporated | Extraction of protein from edible beef bones and product |
| CN1196758C (zh) * | 2002-08-08 | 2005-04-13 | 中国科学院理化技术研究所 | 酶降解骨胶原制备明胶的方法 |
| PL208934B1 (pl) * | 2005-05-12 | 2011-06-30 | Grabek Halina | Sposób wytwarzania żelatyny |
| CN101787078B (zh) * | 2009-01-23 | 2013-01-09 | 香港百特有限公司 | 一种胶原蛋白多肽及其制备方法和用途 |
| CN103060406B (zh) * | 2011-10-18 | 2015-02-18 | 中国科学院理化技术研究所 | 从牲畜骨中提取低分子量胶原蛋白的方法 |
| DE102012110612A1 (de) * | 2012-11-06 | 2014-05-08 | Gelita Ag | Kollagenhydrolysat und dessen Verwendung |
| CN103937859B (zh) * | 2013-01-21 | 2017-10-10 | 中国科学院理化技术研究所 | 一种以骨粉为原料由酶法制取明胶的方法 |
| CN109735591B (zh) * | 2019-03-14 | 2020-11-10 | 舜甫科技(固安)有限公司 | 一种牛骨胶原蛋白肽及其生产方法 |
-
2019
- 2019-11-08 DE DE102019130196.3A patent/DE102019130196A1/de active Pending
-
2020
- 2020-09-28 WO PCT/EP2020/077092 patent/WO2021089243A1/de active Application Filing
- 2020-09-28 JP JP2022526475A patent/JP2023502010A/ja active Pending
- 2020-09-28 EP EP20785702.0A patent/EP4017272A1/de active Pending
- 2020-09-28 MX MX2022005337A patent/MX2022005337A/es unknown
- 2020-09-28 AU AU2020378186A patent/AU2020378186A1/en active Pending
- 2020-09-28 CN CN202080077345.0A patent/CN114845560A/zh active Pending
- 2020-09-28 BR BR112022008115A patent/BR112022008115A2/pt unknown
-
2022
- 2022-05-04 US US17/736,430 patent/US20220256886A1/en active Pending
- 2022-05-09 ZA ZA2022/05099A patent/ZA202205099B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20220256886A1 (en) | 2022-08-18 |
| MX2022005337A (es) | 2022-05-26 |
| ZA202205099B (en) | 2023-11-29 |
| DE102019130196A1 (de) | 2021-05-12 |
| JP2023502010A (ja) | 2023-01-20 |
| WO2021089243A1 (de) | 2021-05-14 |
| AU2020378186A1 (en) | 2022-05-26 |
| CN114845560A (zh) | 2022-08-02 |
| EP4017272A1 (de) | 2022-06-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60238416D1 (de) | Plasmaprotein-matritzes und verfahren zu ihrer herstellung | |
| BR0212654A (pt) | Ativação e expansão de células | |
| BR0318600A (pt) | conjunto implantável para osteossìntese, e, conjunto com pelo menos duas placas de osteossìntese e parafusos ósseos | |
| Miclau et al. | Effects of delayed stabilization on fracture healing | |
| BR0304134A (pt) | Métodos para produção de fluidos de tratamento e de fraturamento, para tratar e para fraturar uma formação subterrânea, e para realizar uma pluralidade de tratamentos de formação subterrânea, e, composição para um fluido de tratamento | |
| KR960701159A (ko) | 젤라틴의 제조방법(method for producing gelatin) | |
| DE69926254D1 (de) | Verwendung von radioliganden zum screening von inhibitoren der herstellung von beta-amyloid peptiden | |
| BR112017027048A2 (pt) | processo para extração de pectina e uso da pectina | |
| ES2106404T3 (es) | Metodo de produccion de caucho bruto. | |
| JP6457503B2 (ja) | 骨再生材料及びその製造方法 | |
| BR112017022821A2 (pt) | solução aquosa homogênea de quitosana injetável apresentando um ph próximo do ph fisiológico | |
| KR101700927B1 (ko) | 고순도 마린콜라겐의 제조 방법 | |
| BR112022008115A2 (pt) | Processo para a produção de peptídeos de colágeno a partir de ossos e peptídeos de colágeno produzidos | |
| CN112852382A (zh) | 一种光固化骨粘合剂及其制备方法 | |
| BR0212757A (pt) | Composição, método para produzir uma composição de fator de crescimento, e, método para tratar um defeito de osso, tendão ou cartilagem | |
| BR0212246A (pt) | Composição indutora da resistência a doença de planta, método para controlar uma doença de planta, e, processo para a produção de uma composição | |
| DE69841553D1 (de) | Verfahren zur herstellung von entölten phosphtiden | |
| BRPI0819960B8 (pt) | dispositivos de reparo de tecido preparados a partir de escamas de peixe e métodos para preparação dos mesmos | |
| BR112022000250A2 (pt) | Composição osteogênica melhorada e método de preparação de composição osteogênica melhorada | |
| Verkhovsky et al. | Organization of stress fibers in cultured fibroblasts after extraction of actin with bovine brain gelsolin-like protein | |
| JPS6363700A (ja) | 細胞培養用高ゲル強度酸可溶性コラーゲンの製法 | |
| BR112022008175A2 (pt) | Processo para a produção de gelatina óssea e gelatina óssea produzida | |
| Pérez-Limiñana et al. | Influence of the extraction temperature on the properties of biopolymers obtained from tannery wastes | |
| BR102016027429B1 (pt) | Processo de extração de colágeno a partir da cartilagem do osso da quilha de frangos | |
| BR0314749A (pt) | Método de coagulação do ácido poli-3-hidroxialcanóico |