BR112021017738A8 - Células-tronco mesenquimais imunomoduladoras - Google Patents
Células-tronco mesenquimais imunomoduladorasInfo
- Publication number
- BR112021017738A8 BR112021017738A8 BR112021017738A BR112021017738A BR112021017738A8 BR 112021017738 A8 BR112021017738 A8 BR 112021017738A8 BR 112021017738 A BR112021017738 A BR 112021017738A BR 112021017738 A BR112021017738 A BR 112021017738A BR 112021017738 A8 BR112021017738 A8 BR 112021017738A8
- Authority
- BR
- Brazil
- Prior art keywords
- mesenchymal stem
- immunomodulating
- stem cells
- present
- cell
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0668—Mesenchymal stem cells from other natural sources
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/02—Compounds of the arachidonic acid pathway, e.g. prostaglandins, leukotrienes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/03—Compounds acting on the NO pathway, e.g. nitrososarginine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/231—Interleukin-10 (IL-10)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19162270 | 2019-03-12 | ||
| PCT/EP2020/056625 WO2020182935A1 (en) | 2019-03-12 | 2020-03-12 | Immunomodulating mesenchymal stem cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112021017738A2 BR112021017738A2 (https=) | 2021-11-16 |
| BR112021017738A8 true BR112021017738A8 (pt) | 2022-08-02 |
Family
ID=65801891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112021017738A BR112021017738A8 (pt) | 2019-03-12 | 2020-03-12 | Células-tronco mesenquimais imunomoduladoras |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20220154147A1 (https=) |
| EP (1) | EP3938494A1 (https=) |
| JP (1) | JP7572367B2 (https=) |
| KR (1) | KR20210139259A (https=) |
| CN (1) | CN113677789B (https=) |
| AU (1) | AU2020235912A1 (https=) |
| BR (1) | BR112021017738A8 (https=) |
| CA (1) | CA3132414A1 (https=) |
| MX (1) | MX2021010739A (https=) |
| WO (1) | WO2020182935A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4146787A4 (en) | 2020-05-08 | 2024-06-26 | Gallant Pet, Inc. | Uterine-derived regenerative cell compositions and uses thereof |
| WO2023280835A1 (en) | 2021-07-08 | 2023-01-12 | Boehringer Ingelheim Veterinary Medicine Belgium | Mesenchymal stem cells for use in the treatment of chronic gingivostomatitis |
| CN117897165A (zh) | 2021-07-08 | 2024-04-16 | 勃林格殷格翰比利时兽医公司 | 用于治疗特应性皮炎的间充质干细胞 |
| US20230022259A1 (en) | 2021-07-08 | 2023-01-26 | Boehringer Ingelheim Veterinary Medicine Belgium | Mesenchymal stem cells for use in the treatment of osteoarthritis in animals |
| CN117915924A (zh) | 2021-07-08 | 2024-04-19 | 勃林格殷格翰比利时兽医公司 | 间充质干细胞用于治疗慢性肾病 |
| AU2023323861A1 (en) | 2022-08-11 | 2025-02-27 | Boehringer Ingelheim Vetmedica Gmbh | Mesenchymal stem cells for use in the treatment of insect-bite hypersensitivity in equines |
| WO2024133886A1 (en) * | 2022-12-23 | 2024-06-27 | Boehringer Ingelheim Veterinary Medicine Belgium | Primed mesenchymal stem cells for use in the treatment of chronic kidney disease |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU755888B2 (en) | 1998-03-18 | 2003-01-02 | Mesoblast International Sarl | Mesenchymal stem cells for prevention and treatment of immune responses in transplantation |
| EP2298864B1 (en) | 2004-03-22 | 2017-10-11 | Mesoblast International Sàrl | Mesenchymal stem cells and uses therefor |
| US20080095749A1 (en) * | 2004-03-22 | 2008-04-24 | Sudeepta Aggarwal | Mesenchymal stem cells and uses therefor |
| US20140017787A1 (en) | 2010-10-11 | 2014-01-16 | Aline M. Betancourt | Mesenchymal stem cells and related therapies |
| ITRM20110403A1 (it) * | 2011-07-28 | 2013-01-29 | Ospedale Pediatrico Bambino Gesu | Microvescicole isolate da cellule mesenchimali come agenti immunosoppressori. |
| KR102246369B1 (ko) * | 2011-11-30 | 2021-04-29 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 중간엽 간질 세포 및 이에 관련된 용도 |
| WO2017160986A1 (en) | 2016-03-16 | 2017-09-21 | Cell Medicine, Inc. | Mesenchymal stem cells with enhanced efficacy |
| US20220333197A1 (en) * | 2019-01-31 | 2022-10-20 | Primegen Biotech, Llc | Treatment of Atopic Dermatitis Using Mesenchymal Stem Cells and Immune Modulation |
-
2020
- 2020-03-12 MX MX2021010739A patent/MX2021010739A/es unknown
- 2020-03-12 CA CA3132414A patent/CA3132414A1/en active Pending
- 2020-03-12 JP JP2021553068A patent/JP7572367B2/ja active Active
- 2020-03-12 KR KR1020217029168A patent/KR20210139259A/ko not_active Ceased
- 2020-03-12 BR BR112021017738A patent/BR112021017738A8/pt unknown
- 2020-03-12 AU AU2020235912A patent/AU2020235912A1/en active Pending
- 2020-03-12 CN CN202080018981.6A patent/CN113677789B/zh active Active
- 2020-03-12 US US17/436,640 patent/US20220154147A1/en not_active Abandoned
- 2020-03-12 EP EP20708513.5A patent/EP3938494A1/en active Pending
- 2020-03-12 WO PCT/EP2020/056625 patent/WO2020182935A1/en not_active Ceased
-
2024
- 2024-12-23 US US18/999,942 patent/US20250122477A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN113677789A (zh) | 2021-11-19 |
| EP3938494A1 (en) | 2022-01-19 |
| JP2022524764A (ja) | 2022-05-10 |
| US20250122477A1 (en) | 2025-04-17 |
| US20220154147A1 (en) | 2022-05-19 |
| CA3132414A1 (en) | 2020-09-17 |
| JP7572367B2 (ja) | 2024-10-23 |
| BR112021017738A2 (https=) | 2021-11-16 |
| CN113677789B (zh) | 2024-11-01 |
| WO2020182935A1 (en) | 2020-09-17 |
| MX2021010739A (es) | 2021-12-15 |
| AU2020235912A1 (en) | 2021-10-07 |
| KR20210139259A (ko) | 2021-11-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112021017738A8 (pt) | Células-tronco mesenquimais imunomoduladoras | |
| BR112022021445A2 (pt) | Métodos e composições para tratar condições inflamatórias associadas com doença infecciosa | |
| CO2019002569A2 (es) | Método para aislar células madre mesenquimales a partir de membrana amniótica de cordón umbilical utilizando un medio de cultivo celular | |
| BR112021015887A8 (pt) | Método para criopreservação de célula-tronco, população de células-tronco, composição de criopreservação, uso de nac, e kit de criopreservação | |
| BR112015030946A8 (pt) | composição compreendendo uma célula ß pancreática não-nativa, método de diferenciação de células progenitoras em células ß pancreáticas in vitro e uso de uma célula ß pancreática não-nativa | |
| CO7170149A2 (es) | Producción mejorada de derivados de ácidos grasos | |
| BR112015017307A2 (pt) | composições de espécies com baixa acidez e métodos para produção e uso das mesmas | |
| BR112022001359A2 (pt) | Método e composição para anticorpos anti-cd73 e variantes | |
| BR112017014060A2 (pt) | composições de bacillus licheniformis rti184 e métodos de uso para beneficiar o crescimento de plantas | |
| BR112017017805A2 (pt) | composição | |
| BR112015022770A8 (pt) | meio e sistema de cultivo da célula livre de xenógeno, livre de albumina, forma concentrada, métodos de diferenciação de células-tronco pluripotentes humanas, para a produção de mesenquimoangioblastos e sistema definido de cultivo da célula para diferenciação hematoendotelial das células- tronco pluripotentes humanas | |
| BR112015021993A8 (pt) | polipeptídeo, métodos para sua produção, métodos para cultivo de uma célula, composição farmacêutica, kit, e meio de cultura celular | |
| MX2019008872A (es) | Prevencion y tratamiento de da?o o enfermedad osea y cartilago. | |
| BR112013002811A8 (pt) | meios básicos simplificados para cultura celular pluripotente de humano | |
| BR112015027563A2 (pt) | métodos para melhorar a regeneração do músculo envelhecido | |
| CY1116365T1 (el) | Στρωματικα βλαστικα κυτταρα | |
| BR112016026956A2 (pt) | método para a produção enzimática de d-eritrose e acetilfosfato". | |
| BR112015010678A2 (pt) | compostos de junta ready-mix usando carboximetilcelulose substituída não uniformemente | |
| WO2023039567A3 (en) | Compositions of induced pluripotent stem cell-derived cells and methods of use thereof | |
| BR112021025116A2 (pt) | Células linfocíticas ativadas e métodos de uso das mesmas para tratar câncer e condições infecciosas | |
| MX2016012372A (es) | Composiciones inmunologicas que contienen histophilus somni atenuado. | |
| MX2018015536A (es) | Extracto de celulas indiferenciadas de mimosa pudica y sus usos en dermocosmeticos. | |
| NZ611531A (en) | Bovine viral diarrhea virus type 1b vaccine compositions and methods | |
| JP2016519939A5 (https=) | ||
| MX2020008897A (es) | Expansion y diferenciacion de citoblastos. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25D | Requested change of name of applicant approved |
Owner name: BOEHRINGER INGELHEIM VETERINARY MEDICINE BELGIUM (BE) |
|
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] |