MX2021010739A - Celulas madre mesenquimales inmunomoduladoras. - Google Patents

Celulas madre mesenquimales inmunomoduladoras.

Info

Publication number
MX2021010739A
MX2021010739A MX2021010739A MX2021010739A MX2021010739A MX 2021010739 A MX2021010739 A MX 2021010739A MX 2021010739 A MX2021010739 A MX 2021010739A MX 2021010739 A MX2021010739 A MX 2021010739A MX 2021010739 A MX2021010739 A MX 2021010739A
Authority
MX
Mexico
Prior art keywords
mesenchymal stem
cell
immunomodulating
stem cells
current invention
Prior art date
Application number
MX2021010739A
Other languages
English (en)
Spanish (es)
Inventor
Jan Spaas
Sarah Broeckx
Original Assignee
Boehringer Ingelheim Veterinary Medicine Belgium
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Veterinary Medicine Belgium filed Critical Boehringer Ingelheim Veterinary Medicine Belgium
Publication of MX2021010739A publication Critical patent/MX2021010739A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662Stem cells
    • C12N5/0668Mesenchymal stem cells from other natural sources
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/02Compounds of the arachidonic acid pathway, e.g. prostaglandins, leukotrienes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/03Compounds acting on the NO pathway, e.g. nitrososarginine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/15Transforming growth factor beta (TGF-β)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20Cytokines; Chemokines
    • C12N2501/23Interleukins [IL]
    • C12N2501/231Interleukin-10 (IL-10)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/11Coculture with; Conditioned medium produced by blood or immune system cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
MX2021010739A 2019-03-12 2020-03-12 Celulas madre mesenquimales inmunomoduladoras. MX2021010739A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19162270 2019-03-12
PCT/EP2020/056625 WO2020182935A1 (en) 2019-03-12 2020-03-12 Immunomodulating mesenchymal stem cells

Publications (1)

Publication Number Publication Date
MX2021010739A true MX2021010739A (es) 2021-12-15

Family

ID=65801891

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021010739A MX2021010739A (es) 2019-03-12 2020-03-12 Celulas madre mesenquimales inmunomoduladoras.

Country Status (10)

Country Link
US (2) US20220154147A1 (https=)
EP (1) EP3938494A1 (https=)
JP (1) JP7572367B2 (https=)
KR (1) KR20210139259A (https=)
CN (1) CN113677789B (https=)
AU (1) AU2020235912A1 (https=)
BR (1) BR112021017738A8 (https=)
CA (1) CA3132414A1 (https=)
MX (1) MX2021010739A (https=)
WO (1) WO2020182935A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021267900A1 (en) 2020-05-08 2023-01-19 Gallant Pet Inc. Uterine-derived regenerative cell compositions and uses thereof
CN117835995A (zh) 2021-07-08 2024-04-05 勃林格殷格翰比利时兽医公司 用于治疗慢性龈口炎的间充质干细胞
EP4366743A1 (en) * 2021-07-08 2024-05-15 Boehringer Ingelheim Veterinary Medicine Belgium Mesenchymal stem cells for use in the treatment of osteoarthritis in animals
TW202319536A (zh) 2021-07-08 2023-05-16 比利時商比利時百靈佳殷格翰動物醫藥公司 用於治療慢性腎病之間葉幹細胞
CN117897165A (zh) * 2021-07-08 2024-04-16 勃林格殷格翰比利时兽医公司 用于治疗特应性皮炎的间充质干细胞
EP4568687A1 (en) 2022-08-11 2025-06-18 Boehringer Ingelheim Vetmedica GmbH Mesenchymal stem cells for use in the treatment of insect-bite hypersensitivity in equines
WO2024133886A1 (en) * 2022-12-23 2024-06-27 Boehringer Ingelheim Veterinary Medicine Belgium Primed mesenchymal stem cells for use in the treatment of chronic kidney disease

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6328960B1 (en) 1998-03-18 2001-12-11 Osiris Therapeutics, Inc. Mesenchymal stem cells for prevention and treatment of immune responses in transplantation
EP3461884B1 (en) * 2004-03-22 2025-05-28 Mesoblast International Sàrl Mesenchymal stem cells and uses therefor
US20080095749A1 (en) * 2004-03-22 2008-04-24 Sudeepta Aggarwal Mesenchymal stem cells and uses therefor
US20140017787A1 (en) * 2010-10-11 2014-01-16 Aline M. Betancourt Mesenchymal stem cells and related therapies
ITRM20110403A1 (it) * 2011-07-28 2013-01-29 Ospedale Pediatrico Bambino Gesu Microvescicole isolate da cellule mesenchimali come agenti immunosoppressori.
SI2785359T1 (sl) * 2011-11-30 2018-11-30 Astellas Institute For Regenerative Medicine Mezenhimske stromalne celice in uporabe povezane z njimi
AU2017235446A1 (en) 2016-03-16 2018-11-08 Cell Medicine, Inc. Mesenchymal stem cells with enhanced efficacy
US20220333197A1 (en) * 2019-01-31 2022-10-20 Primegen Biotech, Llc Treatment of Atopic Dermatitis Using Mesenchymal Stem Cells and Immune Modulation

Also Published As

Publication number Publication date
US20250122477A1 (en) 2025-04-17
EP3938494A1 (en) 2022-01-19
JP2022524764A (ja) 2022-05-10
KR20210139259A (ko) 2021-11-22
CN113677789B (zh) 2024-11-01
US20220154147A1 (en) 2022-05-19
BR112021017738A8 (pt) 2022-08-02
AU2020235912A1 (en) 2021-10-07
CA3132414A1 (en) 2020-09-17
WO2020182935A1 (en) 2020-09-17
CN113677789A (zh) 2021-11-19
JP7572367B2 (ja) 2024-10-23
BR112021017738A2 (https=) 2021-11-16

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