EA202190758A1 - Композиция для индукции гибели клеток, имеющих мутированный ген, и способ индукции гибели клеток, имеющих мутированный ген, с применением композиции - Google Patents

Композиция для индукции гибели клеток, имеющих мутированный ген, и способ индукции гибели клеток, имеющих мутированный ген, с применением композиции

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EA202190758A1
EA202190758A1 EA202190758A EA202190758A EA202190758A1 EA 202190758 A1 EA202190758 A1 EA 202190758A1 EA 202190758 A EA202190758 A EA 202190758A EA 202190758 A EA202190758 A EA 202190758A EA 202190758 A1 EA202190758 A1 EA 202190758A1
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Eurasian Patent Office
Prior art keywords
cell death
composition
induction
mutated gene
mutated
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EA202190758A
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English (en)
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Кёнджэ Мюнг
Тэджун Квон
Ин-Джун Пэк
Чжэ Сон Ра
Юри Сео
Сонмин Юн
Original Assignee
Инститьют Фор Бейсик Сайенс
Унист (Ульсан Нэшнл Инститьют Оф Сайенс Энд Текнолоджи)
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Publication of EA202190758A1 publication Critical patent/EA202190758A1/ru

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Abstract

Настоящее изобретение относится к композиции для индукции гибели клеток с вариациями геномной последовательности, содержащей нуклеазу и расщепляющий агент, и к способу индукции гибели клеток с вариациями геномной последовательности.
EA202190758A 2018-09-12 2019-09-11 Композиция для индукции гибели клеток, имеющих мутированный ген, и способ индукции гибели клеток, имеющих мутированный ген, с применением композиции EA202190758A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20180109214 2018-09-12
PCT/KR2019/011866 WO2020055187A1 (ko) 2018-09-12 2019-09-11 유전자가 변이된 세포의 사멸 유도 조성물 및 상기 조성물을 이용한 유전자가 변형된 세포 사멸 유도 방법

Publications (1)

Publication Number Publication Date
EA202190758A1 true EA202190758A1 (ru) 2021-08-03

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EA202190758A EA202190758A1 (ru) 2018-09-12 2019-09-11 Композиция для индукции гибели клеток, имеющих мутированный ген, и способ индукции гибели клеток, имеющих мутированный ген, с применением композиции

Country Status (9)

Country Link
US (1) US20220049274A1 (ru)
EP (1) EP3851528A4 (ru)
JP (1) JP7410154B2 (ru)
KR (2) KR102131869B1 (ru)
CN (1) CN112955550A (ru)
AU (1) AU2019341000B2 (ru)
CA (1) CA3111477A1 (ru)
EA (1) EA202190758A1 (ru)
WO (1) WO2020055187A1 (ru)

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CN115397997A (zh) * 2020-12-23 2022-11-25 浙江大学 侵染性植物弹状病毒载体及无转基因植物基因组定点编辑的方法
CN113897386A (zh) * 2021-08-03 2022-01-07 南京景瑞康分子医药科技有限公司 一种利用rna干扰机制诱导多位点切割基因组实现选择性杀死细胞的dna系统

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GB0405985D0 (en) * 2004-03-17 2004-04-21 Novartis Forschungsstiftung Kinase
WO2005097189A1 (ja) * 2004-04-09 2005-10-20 Genecare Research Institute Co., Ltd. 染色体安定化に関する遺伝子を標的とする癌細胞特異的アポトーシス誘導剤
CN110066775B (zh) * 2012-10-23 2024-03-19 基因工具股份有限公司 用于切割靶dna的组合物及其用途
SI3132034T1 (sl) * 2014-04-14 2020-12-31 Nemesis Bioscience Ltd. Zdravstveni pripomočki
US20170362580A1 (en) * 2014-12-12 2017-12-21 James Zhu Methods and compositions for selectively eliminating cells of interest
US10166255B2 (en) * 2015-07-31 2019-01-01 Regents Of The University Of Minnesota Intracellular genomic transplant and methods of therapy
EP3368687B1 (en) * 2015-10-27 2021-09-29 The Broad Institute, Inc. Compositions and methods for targeting cancer-specific sequence variations
US10240145B2 (en) * 2015-11-25 2019-03-26 The Board Of Trustees Of The Leland Stanford Junior University CRISPR/Cas-mediated genome editing to treat EGFR-mutant lung cancer
CN107303291A (zh) * 2016-04-18 2017-10-31 无锡杰西医药股份有限公司 含peitc的药物组合物及其在癌症治疗中的应用
BR112019000107A2 (pt) * 2016-07-05 2019-04-09 The Johns Hopkins University composições e métodos com base em crispr / cas9 para o tratamento do câncer
WO2018035388A1 (en) * 2016-08-17 2018-02-22 The Broad Institute, Inc. Novel crispr enzymes and systems

Also Published As

Publication number Publication date
CN112955550A (zh) 2021-06-11
US20220049274A1 (en) 2022-02-17
KR20200030474A (ko) 2020-03-20
AU2019341000B2 (en) 2023-03-16
JP2022502481A (ja) 2022-01-11
JP7410154B2 (ja) 2024-01-09
CA3111477A1 (en) 2020-03-19
AU2019341000A1 (en) 2021-05-20
KR102131869B1 (ko) 2020-07-09
KR20200084843A (ko) 2020-07-13
EP3851528A1 (en) 2021-07-21
WO2020055187A1 (ko) 2020-03-19
EP3851528A4 (en) 2023-12-06

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