BR112020015253A2 - Processo para reduzir endotoxina em gelatina - Google Patents
Processo para reduzir endotoxina em gelatina Download PDFInfo
- Publication number
- BR112020015253A2 BR112020015253A2 BR112020015253-6A BR112020015253A BR112020015253A2 BR 112020015253 A2 BR112020015253 A2 BR 112020015253A2 BR 112020015253 A BR112020015253 A BR 112020015253A BR 112020015253 A2 BR112020015253 A2 BR 112020015253A2
- Authority
- BR
- Brazil
- Prior art keywords
- gelatin
- solution
- salt
- endotoxin
- filtered
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09H—PREPARATION OF GLUE OR GELATINE
- C09H3/00—Isolation of glue or gelatine from raw materials, e.g. by extracting, by heating
- C09H3/02—Purification of solutions of gelatine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J41/00—Anion exchange; Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/08—Use of material as anion exchangers; Treatment of material for improving the anion exchange properties
- B01J41/12—Macromolecular compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J47/00—Ion-exchange processes in general; Apparatus therefor
- B01J47/014—Ion-exchange processes in general; Apparatus therefor in which the adsorbent properties of the ion-exchanger are involved, e.g. recovery of proteins or other high-molecular compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J47/00—Ion-exchange processes in general; Apparatus therefor
- B01J47/12—Ion-exchange processes in general; Apparatus therefor characterised by the use of ion-exchange material in the form of ribbons, filaments, fibres or sheets, e.g. membranes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862640394P | 2018-03-08 | 2018-03-08 | |
| US62/640,394 | 2018-03-08 | ||
| PCT/IB2019/000234 WO2019171173A1 (en) | 2018-03-08 | 2019-03-07 | Process to reduce endotoxin in gelatin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112020015253A2 true BR112020015253A2 (pt) | 2020-12-08 |
Family
ID=66668957
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112020015253-6A BR112020015253A2 (pt) | 2018-03-08 | 2019-03-07 | Processo para reduzir endotoxina em gelatina |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10988638B2 (https=) |
| EP (1) | EP3761956B1 (https=) |
| JP (1) | JP7431741B2 (https=) |
| CN (1) | CN111902129A (https=) |
| AU (1) | AU2019229784A1 (https=) |
| BR (1) | BR112020015253A2 (https=) |
| CA (1) | CA3089172A1 (https=) |
| ES (1) | ES2982045T3 (https=) |
| IL (1) | IL277009B2 (https=) |
| MX (1) | MX2020009112A (https=) |
| WO (1) | WO2019171173A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102793584B1 (ko) | 2016-12-31 | 2025-04-09 | 바이오엑셀 테라퓨틱스 인코포레이티드 | 불안의 치료를 위한 설하 덱스메데토미딘의 용도 |
| PL3813802T3 (pl) | 2018-06-27 | 2025-04-22 | Bioxcel Therapeutics, Inc. | Formulacje błony zawierające deksmedetomidynę i sposoby ich wytwarzania |
| EP3999058A4 (en) | 2019-07-19 | 2023-05-03 | Bioxcel Therapeutics, Inc. | NON-SEDATIVE DEXMEDETOMIDINE-BASED TREATMENT REGIMEN |
| HUE056569T2 (hu) | 2019-07-31 | 2022-02-28 | Catalent Uk Swindon Zydis Ltd | Sûrûség-áramlásmérõ gyógyászati készítmény adagolásához |
| CN111286276A (zh) * | 2020-03-26 | 2020-06-16 | 吉林大学 | 一种林蛙皮明胶的制备方法 |
| WO2022103638A1 (en) | 2020-11-16 | 2022-05-19 | Orcosa Inc. | Cannabinoids in the treatment of autism spectrum disorder |
| US11672761B2 (en) | 2020-11-16 | 2023-06-13 | Orcosa Inc. | Rapidly infusing platform and compositions for therapeutic treatment in humans |
| CN113607903B (zh) * | 2021-07-30 | 2024-03-15 | 振德医疗用品股份有限公司 | 一种检测含有正电荷聚合物细菌内毒素的方法 |
| EP4501129A4 (en) | 2022-03-30 | 2026-03-11 | Toray Industries | PROCESS FOR THE PRODUCTION OF GELATIN OR A CONCENTRATED GELATIN SOLUTION |
| US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
| NL2038119B1 (en) * | 2024-07-02 | 2026-01-16 | Sentryx B V | A method for purifying a gelatin |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB211423A (en) | 1923-10-06 | 1924-02-21 | Leopold Seeger | Improved means for locking nuts |
| GB1548022A (en) | 1976-10-06 | 1979-07-04 | Wyeth John & Brother Ltd | Pharmaceutial dosage forms |
| CA1097233A (en) | 1977-07-20 | 1981-03-10 | George K. E. Gregory | Packages |
| US4374063A (en) | 1981-09-28 | 1983-02-15 | General Foods Corporation | Process for the preparation and purification of gelatin and pyrogen-free gelatin so prepared |
| IE53696B1 (en) | 1981-12-02 | 1989-01-18 | Wyeth John & Brother Ltd | Solid shaped articles |
| JP3039966B2 (ja) * | 1990-07-20 | 2000-05-08 | 新田ゼラチン株式会社 | ゼラチンのイオン性不純物除去方法 |
| ATE187733T1 (de) * | 1994-02-07 | 2000-01-15 | Qiagen Gmbh | Verfahren zur herstellung endotoxinfreier oder an endotoxin abgereicherter nucleinsäuren und/oder oligonucleotide für die gentherapie |
| US5616689A (en) * | 1994-07-13 | 1997-04-01 | Collagen Corporation | Method of controlling structure stability of collagen fibers produced form solutions or dispersions treated with sodium hydroxide for infectious agent deactivation |
| GB9908014D0 (en) | 1999-04-08 | 1999-06-02 | Scherer Corp R P | Pharmaceutical compositions |
| IL149459A0 (en) * | 1999-11-12 | 2002-11-10 | Fibrogen Inc | Recombinant gelatins |
| DE10010342A1 (de) * | 2000-03-06 | 2001-09-20 | Merck Patent Gmbh | Verfahren zur Abreicherung von Endotoxinen |
| JP4762785B2 (ja) * | 2005-06-02 | 2011-08-31 | 西川ゴム工業株式会社 | ゼラチンスポンジ |
| JP5328077B2 (ja) * | 2006-02-10 | 2013-10-30 | エア・ウォーター株式会社 | 低エンドトキシン化ゼラチンの製造方法 |
| JP4404866B2 (ja) * | 2006-03-03 | 2010-01-27 | ゼライス株式会社 | エンドトキシン含有量を低減したゼラチンの製造方法および低エンドトキシンゼラチン |
| JP4099541B2 (ja) | 2006-07-19 | 2008-06-11 | ゼライス株式会社 | ペプチド精製物の製造方法 |
| JP2010520320A (ja) * | 2007-02-28 | 2010-06-10 | リポクセン テクノロジーズ リミテッド | ポリシアル酸におけるエンドトキシンの低減 |
| WO2009154440A1 (en) * | 2008-06-19 | 2009-12-23 | Bender Analytical Holding B.V. | Method for removing impurities from biopolymer material |
| US10548839B2 (en) | 2010-03-16 | 2020-02-04 | Wei Tian | Process of manufacturing a lyophilized fast dissolving, multi-phasic dosage form |
| CN102423721B (zh) * | 2011-08-18 | 2013-07-24 | 浙江工业大学 | 一种磁性阴离子交换剂及其作为内毒素吸附介质的应用 |
| US20140142200A1 (en) | 2012-11-16 | 2014-05-22 | Eyegenix LLC | Keratoprosthesis |
| CN104370997B (zh) * | 2014-09-24 | 2018-07-31 | 陈辉 | 去除生物制品中细菌内毒素的试剂盒、方法及其生物制品的制备方法 |
-
2019
- 2019-03-07 IL IL277009A patent/IL277009B2/en unknown
- 2019-03-07 CA CA3089172A patent/CA3089172A1/en active Pending
- 2019-03-07 WO PCT/IB2019/000234 patent/WO2019171173A1/en not_active Ceased
- 2019-03-07 MX MX2020009112A patent/MX2020009112A/es unknown
- 2019-03-07 US US16/295,223 patent/US10988638B2/en active Active
- 2019-03-07 ES ES19727055T patent/ES2982045T3/es active Active
- 2019-03-07 EP EP19727055.6A patent/EP3761956B1/en active Active
- 2019-03-07 BR BR112020015253-6A patent/BR112020015253A2/pt not_active IP Right Cessation
- 2019-03-07 AU AU2019229784A patent/AU2019229784A1/en not_active Abandoned
- 2019-03-07 CN CN201980017710.6A patent/CN111902129A/zh active Pending
- 2019-03-07 JP JP2020546887A patent/JP7431741B2/ja active Active
-
2021
- 2021-03-24 US US17/210,965 patent/US20210207003A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2019229784A1 (en) | 2020-08-13 |
| WO2019171173A1 (en) | 2019-09-12 |
| JP2021516685A (ja) | 2021-07-08 |
| IL277009A (en) | 2020-10-29 |
| CN111902129A (zh) | 2020-11-06 |
| JP7431741B2 (ja) | 2024-02-15 |
| ES2982045T3 (es) | 2024-10-14 |
| RU2020132925A (ru) | 2022-04-08 |
| MX2020009112A (es) | 2020-10-01 |
| US20190276707A1 (en) | 2019-09-12 |
| US20210207003A1 (en) | 2021-07-08 |
| IL277009B1 (en) | 2024-02-01 |
| US10988638B2 (en) | 2021-04-27 |
| CA3089172A1 (en) | 2019-09-12 |
| EP3761956A1 (en) | 2021-01-13 |
| IL277009B2 (en) | 2024-06-01 |
| EP3761956C0 (en) | 2024-06-12 |
| EP3761956B1 (en) | 2024-06-12 |
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| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2822 DE 04/02/2025. |