BR112019025635A2 - Recipiente com partículas para uso com inalador - Google Patents
Recipiente com partículas para uso com inalador Download PDFInfo
- Publication number
- BR112019025635A2 BR112019025635A2 BR112019025635-0A BR112019025635A BR112019025635A2 BR 112019025635 A2 BR112019025635 A2 BR 112019025635A2 BR 112019025635 A BR112019025635 A BR 112019025635A BR 112019025635 A2 BR112019025635 A2 BR 112019025635A2
- Authority
- BR
- Brazil
- Prior art keywords
- particles
- capsule
- container
- nicotine
- fact
- Prior art date
Links
- RUDZVCSDFMADOR-UHFFFAOYSA-N O=NCC1CCC1 Chemical compound O=NCC1CCC1 RUDZVCSDFMADOR-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
- A24B15/241—Extraction of specific substances
- A24B15/243—Nicotine
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
- A24B15/305—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances of undetermined constitution characterised by their preparation
- A24B15/306—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances of undetermined constitution characterised by their preparation one reactant being an amino acid or a protein, e.g. Maillard's reaction
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
- A24B15/34—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a carbocyclic ring other than a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
- A24B15/36—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring
- A24B15/40—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring having only oxygen or sulfur as hetero atoms
- A24B15/403—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances containing a heterocyclic ring having only oxygen or sulfur as hetero atoms having only oxygen as hetero atoms
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/20—Devices using solid inhalable precursors
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
- A24F40/42—Cartridges or containers for inhalable precursors
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F42/00—Simulated smoking devices other than electrically operated; Component parts thereof; Manufacture or testing thereof
- A24F42/20—Devices without heating means
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F42/00—Simulated smoking devices other than electrically operated; Component parts thereof; Manufacture or testing thereof
- A24F42/60—Constructional details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0035—Piercing means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/06—Inhaling appliances shaped like cigars, cigarettes or pipes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Otolaryngology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17178416 | 2017-06-28 | ||
| EP17178416.8 | 2017-06-28 | ||
| PCT/IB2018/054720 WO2019003118A1 (en) | 2017-06-28 | 2018-06-26 | CONTAINER WITH PARTICLES FOR USE WITH INHALER |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112019025635A2 true BR112019025635A2 (pt) | 2020-06-23 |
Family
ID=59253389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112019025635-0A BR112019025635A2 (pt) | 2017-06-28 | 2018-06-26 | Recipiente com partículas para uso com inalador |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US12263242B2 (enExample) |
| EP (1) | EP3644962A1 (enExample) |
| JP (2) | JP2020527377A (enExample) |
| KR (2) | KR20240119177A (enExample) |
| CN (2) | CN110709063A (enExample) |
| AU (1) | AU2018292732B2 (enExample) |
| BR (1) | BR112019025635A2 (enExample) |
| CA (1) | CA3061895A1 (enExample) |
| IL (1) | IL269275B2 (enExample) |
| MX (1) | MX2019014671A (enExample) |
| MY (1) | MY200258A (enExample) |
| PH (1) | PH12019502100A1 (enExample) |
| UA (1) | UA126238C2 (enExample) |
| WO (1) | WO2019003118A1 (enExample) |
| ZA (1) | ZA201905999B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019524648A (ja) * | 2016-06-30 | 2019-09-05 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | ニコチン粒子および組成物 |
| EP3908133B1 (de) * | 2019-01-07 | 2023-10-11 | LuxCan Innovation S.A. | Vorrichtung zum erzeugen eines gasförmigen wirkstoffs oder eines gasförmigen wirkstoffgemischs |
| JPWO2020189787A1 (enExample) * | 2019-03-19 | 2020-09-24 | ||
| EP3794996A1 (en) * | 2019-09-20 | 2021-03-24 | Nerudia Limited | Smoking substitute apparatus |
| CN114375210B (zh) * | 2019-09-26 | 2024-08-27 | 菲利普莫里斯生产公司 | 具有扭转型远端元件的吸入器制品 |
| ES2965397T3 (es) * | 2019-11-14 | 2024-04-15 | Philip Morris Products Sa | Formulación mejorada de polvo seco con sabor a tabaco |
| CN116137819A (zh) * | 2020-07-24 | 2023-05-19 | 菲利普莫里斯生产公司 | 吸入器制品 |
| IL300741A (en) * | 2020-09-03 | 2023-04-01 | Philip Morris Products Sa | Active powder compositions with low hygroscopicity |
| US12096803B2 (en) * | 2020-11-04 | 2024-09-24 | Anthony Hamilton | E-cigarette vaporizer cartridge filling device |
| KR20230119122A (ko) * | 2020-12-11 | 2023-08-16 | 필립모리스 프로덕츠 에스.에이. | 단일 평면 천공 요소를 갖는 흡입기 시스템 |
| EP4387474B1 (en) * | 2021-08-19 | 2025-07-16 | Philip Morris Products S.A. | Aerosol-forming substrate in the form of solid unitary body from two particulate materials |
| EP4278912A4 (en) * | 2022-03-25 | 2024-05-08 | China Tobacco Yunnan Industrial Co., Ltd | GRANULAR AEROSOL GENERATING PRODUCT WITHOUT THE USE OF A MULTI-HOLE FIRMWARE SECTION |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1242211A (en) | 1967-08-08 | 1971-08-11 | Fisons Pharmaceuticals Ltd | Pharmaceutical composition |
| US6234169B1 (en) | 1998-08-14 | 2001-05-22 | Arthur Slutsky | Inhaler |
| US6766799B2 (en) | 2001-04-16 | 2004-07-27 | Advanced Inhalation Research, Inc. | Inhalation device |
| WO2004060351A2 (en) * | 2002-12-31 | 2004-07-22 | Nektar Therapeutics | Pharmaceutical formulation with an insoluble active agent for pulmonary administration |
| US20060254583A1 (en) * | 2003-03-20 | 2006-11-16 | Arthur Deboeck | Dry powder inhaler system |
| US8037880B2 (en) | 2006-04-07 | 2011-10-18 | The University Of Western Ontario | Dry powder inhaler |
| ES2596263T3 (es) | 2006-10-25 | 2017-01-05 | Novartis Ag | Aparato de dispersión de polvo |
| BRPI0821111A2 (pt) * | 2007-12-05 | 2015-06-16 | Novartis Ag | Recptáculo para uma formulação farmacêutica aerossoliza´vel |
| US8772886B2 (en) | 2010-07-26 | 2014-07-08 | Avalanche Technology, Inc. | Spin transfer torque magnetic random access memory (STTMRAM) having graded synthetic free layer |
| PL2714162T3 (pl) * | 2011-05-27 | 2020-08-24 | Boehringer Ingelheim International Gmbh | Inhalator i kapsułka do inhalatora |
| EP2614848B1 (de) * | 2012-01-13 | 2020-07-01 | Boehringer Ingelheim International GmbH | Inhalator und Kapsel für einen Inhalator |
| US10786637B2 (en) * | 2011-07-13 | 2020-09-29 | Pharmaxis Ltd. | Delivery devices |
| US20140150787A1 (en) * | 2012-12-04 | 2014-06-05 | Civitas Therapeutics, Inc. | Devices and methods for puncturing a capsule to release a powdered medicament therefrom |
| JP6672258B2 (ja) * | 2014-04-08 | 2020-03-25 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | ニコチン製剤及びその作製方法 |
| RU2680422C2 (ru) | 2014-04-28 | 2019-02-21 | Филип Моррис Продактс С.А. | Ингалятор ароматизированного никотинового порошка |
| KR102395956B1 (ko) | 2014-06-20 | 2022-05-10 | 필립모리스 프로덕츠 에스.에이. | 기류 관리 수단을 보유한 니코틴 분말 전달 시스템 |
| GB201411526D0 (en) | 2014-06-27 | 2014-08-13 | British American Tobacco Co | Powder |
| US11338099B2 (en) * | 2014-12-24 | 2022-05-24 | Philip Morris Products S.A. | Nicotine powder delivery system |
| US11224594B2 (en) * | 2015-09-16 | 2022-01-18 | Philip Morris Products S.A. | Nicotine formulations and methods of making and using the same |
| US9585835B1 (en) * | 2015-09-16 | 2017-03-07 | Sansa Corporation (Barbados) Inc. | Inhalable nicotine formulations and methods of making and using the same |
| US10149844B2 (en) | 2015-09-16 | 2018-12-11 | Philip Morris Products S.A. | Inhalable nicotine formulations, and methods of making and using thereof |
| WO2017109678A1 (en) * | 2015-12-24 | 2017-06-29 | Philip Morris Products S.A. | Nicotine particle capsule |
| MY186270A (en) | 2015-12-24 | 2021-07-01 | Philip Morris Products Sa | Flavoured nicotine powder |
| AU2017369977A1 (en) * | 2016-11-30 | 2019-04-11 | Philip Morris Products S.A. | Inhaler with swirl end plug |
-
2018
- 2018-06-26 MX MX2019014671A patent/MX2019014671A/es unknown
- 2018-06-26 CN CN201880037255.1A patent/CN110709063A/zh active Pending
- 2018-06-26 CA CA3061895A patent/CA3061895A1/en active Pending
- 2018-06-26 IL IL269275A patent/IL269275B2/en unknown
- 2018-06-26 KR KR1020247025314A patent/KR20240119177A/ko active Pending
- 2018-06-26 CN CN202410125766.6A patent/CN117958505A/zh active Pending
- 2018-06-26 EP EP18747004.2A patent/EP3644962A1/en active Pending
- 2018-06-26 WO PCT/IB2018/054720 patent/WO2019003118A1/en not_active Ceased
- 2018-06-26 UA UAA201910201A patent/UA126238C2/uk unknown
- 2018-06-26 KR KR1020197036758A patent/KR20200023285A/ko not_active Ceased
- 2018-06-26 US US16/623,923 patent/US12263242B2/en active Active
- 2018-06-26 BR BR112019025635-0A patent/BR112019025635A2/pt unknown
- 2018-06-26 JP JP2019569310A patent/JP2020527377A/ja active Pending
- 2018-06-26 MY MYPI2019005209A patent/MY200258A/en unknown
- 2018-06-26 AU AU2018292732A patent/AU2018292732B2/en active Active
-
2019
- 2019-09-11 ZA ZA2019/05999A patent/ZA201905999B/en unknown
- 2019-09-13 PH PH12019502100A patent/PH12019502100A1/en unknown
-
2023
- 2023-03-13 JP JP2023038764A patent/JP2023078269A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| RU2019141658A3 (enExample) | 2021-10-14 |
| AU2018292732A1 (en) | 2019-10-03 |
| CA3061895A1 (en) | 2019-01-03 |
| IL269275B (en) | 2022-12-01 |
| MY200258A (en) | 2023-12-17 |
| ZA201905999B (en) | 2021-01-27 |
| US12263242B2 (en) | 2025-04-01 |
| PH12019502100A1 (en) | 2020-03-16 |
| IL269275B2 (en) | 2023-04-01 |
| CN110709063A (zh) | 2020-01-17 |
| AU2018292732B2 (en) | 2024-07-04 |
| KR20200023285A (ko) | 2020-03-04 |
| UA126238C2 (uk) | 2022-09-07 |
| RU2019141658A (ru) | 2021-07-28 |
| US20200196674A1 (en) | 2020-06-25 |
| EP3644962A1 (en) | 2020-05-06 |
| KR20240119177A (ko) | 2024-08-06 |
| JP2023078269A (ja) | 2023-06-06 |
| JP2020527377A (ja) | 2020-09-10 |
| MX2019014671A (es) | 2020-02-07 |
| CN117958505A (zh) | 2024-05-03 |
| IL269275A (en) | 2019-11-28 |
| WO2019003118A1 (en) | 2019-01-03 |
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