BR112018016287A2 - sistema de perfusão, método para administrar diretamente a um paciente em necessidade do mesmo uma dose de um fármaco antineoplásico e recipiente de perfusão - Google Patents

sistema de perfusão, método para administrar diretamente a um paciente em necessidade do mesmo uma dose de um fármaco antineoplásico e recipiente de perfusão

Info

Publication number
BR112018016287A2
BR112018016287A2 BR112018016287A BR112018016287A BR112018016287A2 BR 112018016287 A2 BR112018016287 A2 BR 112018016287A2 BR 112018016287 A BR112018016287 A BR 112018016287A BR 112018016287 A BR112018016287 A BR 112018016287A BR 112018016287 A2 BR112018016287 A2 BR 112018016287A2
Authority
BR
Brazil
Prior art keywords
patient
antineoplastic drug
dose
infusion container
infusion
Prior art date
Application number
BR112018016287A
Other languages
English (en)
Inventor
Ganorkar Kirti
Kane Prashant
Kumar Samarth
Balaram Bhowmick Subhas
Original Assignee
Sun Pharmaceutical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Pharmaceutical Ind Ltd filed Critical Sun Pharmaceutical Ind Ltd
Publication of BR112018016287A2 publication Critical patent/BR112018016287A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10—Bag-type containers
    • A61J1/12—Bag-type containers with means for holding samples of contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1407—Infusion of two or more substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16804—Flow controllers
    • A61M5/16827—Flow controllers controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/60—General characteristics of the apparatus with identification means
    • A61M2205/6009—General characteristics of the apparatus with identification means for matching patient with his treatment, e.g. to improve transfusion security
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)

Abstract

a presente invenção refere-se a um recipiente de perfusão para administrar diretamente aos pacientes uma dose de um fármaco antineoplásico calculada de acordo com um parâmetro do paciente, em que o primeiro recipiente de perfusão compreende uma solução de fármaco antineoplásico a uma concentração e o volume de modo que a quantidade de fármaco antineoplásico no recipiente é igual à dose calculada para um paciente mas menor do que a dose calculada para um segundo paciente, a dose calculada é proporcionada para um primeiro paciente dentro de 5% de variação por administrar diretamente o volume total da solução de fármaco antineoplásico a partir do primeiro recipiente de perfusão, adicionalmente o primeiro recipiente de perfusão é acompanhado por um segundo recipiente de perfusão de recarga que compreende uma solução de fármaco antineoplásico a uma concentração e o volume de modo que a dose calculada é proporcionada dentro de 5% de variação por administrar diretamente o volume total da solução de fármaco antineoplásico a partir do primeiro recipiente de perfusão e do segundo recipiente de recarga para o segundo paciente.
BR112018016287A 2016-02-09 2017-02-09 sistema de perfusão, método para administrar diretamente a um paciente em necessidade do mesmo uma dose de um fármaco antineoplásico e recipiente de perfusão BR112018016287A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201621004576 2016-02-09
PCT/IN2017/050055 WO2017138023A1 (en) 2016-02-09 2017-02-09 Perfusion system

Publications (1)

Publication Number Publication Date
BR112018016287A2 true BR112018016287A2 (pt) 2018-12-18

Family

ID=59563072

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018016287A BR112018016287A2 (pt) 2016-02-09 2017-02-09 sistema de perfusão, método para administrar diretamente a um paciente em necessidade do mesmo uma dose de um fármaco antineoplásico e recipiente de perfusão

Country Status (18)

Country Link
US (3) US11554207B2 (pt)
EP (2) EP3413862B8 (pt)
JP (2) JP7059190B2 (pt)
KR (1) KR102524115B1 (pt)
CN (1) CN109069342A (pt)
AU (1) AU2017218801B2 (pt)
BR (1) BR112018016287A2 (pt)
CA (1) CA3014168C (pt)
ES (1) ES2968415T3 (pt)
HK (1) HK1258361A1 (pt)
IL (1) IL261038B2 (pt)
MX (2) MX2018009670A (pt)
PH (1) PH12018501693A1 (pt)
PL (1) PL3413862T3 (pt)
RU (1) RU2728822C2 (pt)
SA (1) SA518392177B1 (pt)
WO (1) WO2017138023A1 (pt)
ZA (1) ZA201805610B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10098813B2 (en) 2014-09-03 2018-10-16 Sun Pharmaceutical Industries Limited Perfusion dosage form
EP3804686B1 (en) * 2017-10-10 2023-08-30 Sun Pharmaceutical Industries Ltd Intravenous infusion dosage form for pemetrexed

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5217860A (en) * 1991-07-08 1993-06-08 The American National Red Cross Method for preserving organs for transplantation by vitrification
US5856081A (en) * 1991-07-08 1999-01-05 The American National Red Cross Computer controlled cryoprotectant perfusion apparatus
DE4336336A1 (de) * 1992-11-23 1994-05-26 Lang Volker Kasetteninfusionssystem
US5786344A (en) 1994-07-05 1998-07-28 Arch Development Corporation Camptothecin drug combinations and methods with reduced side effects
CN2211286Y (zh) * 1994-09-24 1995-11-01 陈利生 加温灌注抗癌机
JPH09168577A (ja) * 1995-12-20 1997-06-30 Sekisui Chem Co Ltd 癌治療用血液バッグ
US5896989A (en) 1998-02-20 1999-04-27 Bracco Research Usa Flexible medical container packaging
US6771697B1 (en) 1998-06-23 2004-08-03 Pctel, Inc. Spread spectrum handshake for digital subscriber line telecommunications systems
US7235583B1 (en) 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
WO2000066125A1 (en) 1999-04-29 2000-11-09 Aventis Pharma S.A. Method for treating cancer using camptothecin derivatives and 5-fluorouracil
US7243689B2 (en) 2000-02-11 2007-07-17 Medical Instill Technologies, Inc. Device with needle penetrable and laser resealable portion and related method
AU6147301A (en) 2000-05-15 2001-11-26 Celgene Corp Compositions and methods for the treatment of colorectal cancer
US7352770B1 (en) 2000-08-04 2008-04-01 Intellon Corporation Media access control protocol with priority and contention-free intervals
US7552088B2 (en) 2000-10-02 2009-06-23 International Business Machines Corporation Personally customizable credit card accounts
US6954505B2 (en) 2001-03-29 2005-10-11 Texas Instruments Incorporated Discrete multitone modulation with reduced peak-to-average ratio using unloaded subchannels
US20030039306A1 (en) 2001-04-06 2003-02-27 Redfern Arthur John Low peak-to-average ratio quiescent mode architecture and signal design method for DMT modems
US20030031240A1 (en) 2001-07-31 2003-02-13 Redfern Arthur J. Downstream only suspend-type Q-Mode
US6476068B1 (en) 2001-12-06 2002-11-05 Pharmacia Italia, S.P.A. Platinum derivative pharmaceutical formulations
CA2497664C (en) 2002-09-03 2008-11-18 Medical Instill Technologies, Inc. Sealed containers and methods of making and filling same
JP2004166847A (ja) * 2002-11-18 2004-06-17 Otsuka Pharmaceut Factory Inc 点滴用調合装置、混合管、薬液容器、混合液容器、点滴用調合システムおよび点滴用の調合方法
ATE423584T1 (de) * 2002-12-23 2009-03-15 Medtronic Inc Systeme und methoden zum einstellen der dichte einer medizinischen lösung
DE102005022428A1 (de) * 2005-05-14 2006-11-16 B. Braun Medizinelektronik Gmbh & Co. Kg Verfahren und Vorrichtung zur Steuerung einer Mehrzahl von Infusionspumpen
CA2663571A1 (en) 2006-09-13 2008-03-20 Nuvelo, Inc. Methods for treating cancer
US20110177161A1 (en) 2007-05-24 2011-07-21 Dr. Reddy's Laboratories Limited Pharmaceutical compositions of [5(s)-(2'-hydroxyethoxy)-20(s)-camptothecin
JP2009034462A (ja) * 2007-07-31 2009-02-19 Koosei Advance:Kk 膵臓治療用灌流システム
MX2010009453A (es) 2008-02-29 2011-03-01 Eagle Pharmaceuticals Inc Soluciones de topotecano listas para utilizarse.
CN102652843B (zh) * 2009-07-01 2015-09-30 弗雷塞尼斯医疗保健控股公司 药物输送装置和相关系统以及方法
FR2951951A1 (fr) * 2009-11-05 2011-05-06 Centre Nat Rech Scient Systeme de perfusion securise et procede de mise en oeuvre
FR2951927A1 (fr) * 2009-11-05 2011-05-06 Centre Nat Rech Scient Dispositif de prelevement de liquide corporel et procede de mise en oeuvre.
AR085215A1 (es) 2011-02-15 2013-09-18 Sanofi Aventis Deutschland Interfaz de dispensacion para uso con un dispositivo dispensador de farmacos que libera dos o mas agentes farmaceuticos
EP2720735A4 (en) * 2011-06-20 2015-03-11 Renaudia Medical Llc DISTRIBUTED MEDICATION DELIVERY SYSTEM AND METHOD HAVING AUTONOMOUS DELIVERY DEVICES
US9233776B2 (en) * 2012-06-07 2016-01-12 Bayer Healthcare Llc Molecular imaging vial transport container and fluid injection system interface
KR20150034172A (ko) 2012-06-13 2015-04-02 닥터.피와이 인스터튜트, 엘엘씨 관통가능한 격막 및 마개 니들을 갖는 장치
US9125805B2 (en) 2012-06-27 2015-09-08 Xeris Pharmaceuticals, Inc. Stable formulations for parenteral injection of small molecule drugs
TW201536348A (zh) * 2013-07-15 2015-10-01 Alchemia Oncology Pty Ltd 預製備藥物以用於醫療用途的方法
US10098813B2 (en) 2014-09-03 2018-10-16 Sun Pharmaceutical Industries Limited Perfusion dosage form

Also Published As

Publication number Publication date
EP3413862B8 (en) 2024-03-13
PH12018501693A1 (en) 2019-05-15
IL261038B2 (en) 2024-06-01
EP4275673A3 (en) 2023-12-27
PL3413862T3 (pl) 2024-03-18
JP2019504699A (ja) 2019-02-21
KR20180120171A (ko) 2018-11-05
NZ745728A (en) 2023-08-25
RU2728822C2 (ru) 2020-07-31
ES2968415T3 (es) 2024-05-09
SA518392177B1 (ar) 2022-08-04
RU2018131914A3 (pt) 2020-04-30
ZA201805610B (en) 2019-05-29
CA3014168C (en) 2023-07-04
EP3413862B1 (en) 2023-10-18
IL261038B1 (en) 2024-02-01
EP3413862A1 (en) 2018-12-19
US20230158226A1 (en) 2023-05-25
IL261038A (en) 2018-10-31
AU2017218801B2 (en) 2021-11-25
MX2022010782A (es) 2022-09-19
US20200360598A1 (en) 2020-11-19
CA3014168A1 (en) 2017-08-17
US20210100947A1 (en) 2021-04-08
EP4275673A2 (en) 2023-11-15
MX2018009670A (es) 2019-09-04
EP3413862A4 (en) 2019-07-17
RU2018131914A (ru) 2020-03-11
CN109069342A (zh) 2018-12-21
JP7059190B2 (ja) 2022-04-25
KR102524115B1 (ko) 2023-04-20
HK1258361A1 (zh) 2019-11-08
US11554207B2 (en) 2023-01-17
AU2017218801A1 (en) 2018-09-13
WO2017138023A1 (en) 2017-08-17
JP2022068326A (ja) 2022-05-09
US11253642B2 (en) 2022-02-22

Similar Documents

Publication Publication Date Title
BR112014028600A8 (pt) Formulações de suspensão compreendendo anticorpo monoclonal de alta concentração, seu método de preparação, seu uso e dispositivo para sua administração subcutânea, e método para produção de um artigo de fabricação
BR112014018924A8 (pt) Método de gerar uma etiqueta de dosagem customizada para um dispositivo de distribuição de medicamento
BR112018071699A2 (pt) sistema de liberação médica
BR112014012522A2 (pt) método para encher um reservatório, reservatório e conjunto para encher um reservatório
BR112014018520A8 (pt) kit de combinação de seringa de segurança e dose de segurança
BR112016000194A8 (pt) forma de dosagem resistente à violação contendo o polímero de acetato de etileno-vinila
BR112014003414A2 (pt) método de produção de níveis fisiológicos e terapêuticos de óxido nítrico através de um sistema de entrega oral
BR112015022896A2 (pt) drogas de alta penetração e suas composições para o tratamento de doenças de parkinson
BR112018011266A2 (pt) ?composição farmacêutica, recipiente vedado, inalador dosimetrado, e, métodos para tratar um paciente que sofre ou é propenso a sofrer de um distúrbio respiratório e para estabilizar uma composição farmacêutica?
MY191380A (en) Stabilized fixed dose drug composition having mometasone and olopatadine
BR112015022465A2 (pt) método para tratamento não-tóxico para síndrome de abstinência de drogas
CL2017001859A1 (es) Inhalador de polvo seco que comprende propionato de fluticasona y xinafosfato de salmeterol
EP4368175A3 (en) Perfusion dosage form
AR089862A1 (es) USO DE LAQUINIMOD PARA EL TRATAMIENTO DE PACIENTES CON ENFERMEDAD DE CROHN EN QUIENES FRACASO UNA TERAPIA ANTI-FACTOR DE NECROSIS TUMORAL a (ANTI-TNFa) DE PRIMERA LINEA
BR112012030641A2 (pt) métodos e composições para terapia farmacêutica oral
BR112015011778A2 (pt) métodos para administrar e avaliar drogas de expulsão de nitrogênio para o tratamento de encefalopatia hepática
BR112017006272A2 (pt) composição farmacêutica para tratar colite ulcerativa.
BR112016027435A2 (pt) formulação inovadora de meloxicam
BR112015023481A2 (pt) composição de lipossoma de liberação controlada de fármaco
MX2017008000A (es) Sistema de inyeccion de un solo uso.
MX2018000258A (es) Dispositivo de suministro de un solo uso.
BR112017011663A2 (pt) dispensador de insulina, método de controle dos níveis de glicose em um paciente, e, sistema.
BR112018016287A2 (pt) sistema de perfusão, método para administrar diretamente a um paciente em necessidade do mesmo uma dose de um fármaco antineoplásico e recipiente de perfusão
BR112018000018A2 (pt) dispositivo e sistema de liberação de uso único com aspectos de segurança
BR112017022984A2 (pt) dispositivo para facilitar o posicionamento de um cateter para administrar um medicamento em um paciente que esteja respirando espontaneamente

Legal Events

Date Code Title Description
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09T Decision of refusal: decision cancelled [chapter 9.2.1 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 9.2 NA RPI NO 2734 DE 30/05/2023 POR TER SIDO INDEVIDA.

B09B Patent application refused [chapter 9.2 patent gazette]
B154 Notification of filing of divisional application [chapter 15.50 patent gazette]

Free format text: O PEDIDO FOI DIVIDIDO NO BR122023013797-3 PROTOCOLO 870230060309 EM 10/07/2023 17:05.

B12B Appeal against refusal [chapter 12.2 patent gazette]