BR112017021789A2 - processo para isolamento e purificação de ambrox - Google Patents

processo para isolamento e purificação de ambrox

Info

Publication number
BR112017021789A2
BR112017021789A2 BR112017021789A BR112017021789A BR112017021789A2 BR 112017021789 A2 BR112017021789 A2 BR 112017021789A2 BR 112017021789 A BR112017021789 A BR 112017021789A BR 112017021789 A BR112017021789 A BR 112017021789A BR 112017021789 A2 BR112017021789 A2 BR 112017021789A2
Authority
BR
Brazil
Prior art keywords
ambrox
isolation
purification
purifying
isolating
Prior art date
Application number
BR112017021789A
Other languages
English (en)
Other versions
BR112017021789B1 (pt
Inventor
EICHHORN Eric
Original Assignee
Givaudan Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Givaudan Sa filed Critical Givaudan Sa
Publication of BR112017021789A2 publication Critical patent/BR112017021789A2/pt
Publication of BR112017021789B1 publication Critical patent/BR112017021789B1/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00—Purification; Separation; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92—Naphthofurans; Hydrogenated naphthofurans
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B9/00—Essential oils; Perfumes
    • C11B9/0069—Heterocyclic compounds
    • C11B9/0073—Heterocyclic compounds containing only O or S as heteroatoms
    • C11B9/0076—Heterocyclic compounds containing only O or S as heteroatoms the hetero rings containing less than six atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y504/00—Intramolecular transferases (5.4)
    • C12Y504/99—Intramolecular transferases (5.4) transferring other groups (5.4.99)
    • C12Y504/99017—Squalene--hopene cyclase (5.4.99.17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Treating Waste Gases (AREA)
  • Cosmetics (AREA)
  • Furan Compounds (AREA)

Abstract

a presente invenção refere-se a um método de isolar e purificar (-)-ambrox de uma mistura de reação compreendendo (-)-ambrox e um ou mais dos compostos (ii), (iii) e (iv):
BR112017021789-9A 2015-04-24 2016-04-22 Método de isolamento e purificação de ambrox e método de melhorar ou acentuar o odor de ambrox BR112017021789B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1507170.7 2015-04-24
GBGB1507170.7A GB201507170D0 (en) 2015-04-24 2015-04-24 Process
PCT/EP2016/058997 WO2016170106A1 (en) 2015-04-24 2016-04-22 Process for isolating and purifying ambrox

Publications (2)

Publication Number Publication Date
BR112017021789A2 true BR112017021789A2 (pt) 2018-07-31
BR112017021789B1 BR112017021789B1 (pt) 2022-11-29

Family

ID=53488739

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017021789-9A BR112017021789B1 (pt) 2015-04-24 2016-04-22 Método de isolamento e purificação de ambrox e método de melhorar ou acentuar o odor de ambrox

Country Status (13)

Country Link
US (1) US10294211B2 (pt)
EP (1) EP3286309B1 (pt)
JP (3) JP7246133B2 (pt)
CN (1) CN107548418B (pt)
BR (1) BR112017021789B1 (pt)
CO (1) CO2017010720A2 (pt)
ES (1) ES2856887T3 (pt)
GB (1) GB201507170D0 (pt)
IL (1) IL254836B2 (pt)
MX (1) MX2017013100A (pt)
RU (1) RU2720094C2 (pt)
SG (1) SG11201708085TA (pt)
WO (1) WO2016170106A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201507207D0 (en) 2015-04-24 2015-06-10 Givaudan Sa Enzymes and applications thereof
GB201618090D0 (en) * 2016-10-26 2016-12-07 Givaudan Sa Product
US11091752B2 (en) * 2017-02-24 2021-08-17 International Flavors & Fragrances Inc. Squalene hopene cyclase and use thereof for producing ambroxan
EP3476822A1 (en) 2017-10-31 2019-05-01 Givaudan SA Process of making organic compounds
GB202011823D0 (en) 2020-07-30 2020-09-16 Givaudan Sa Method
GB202115120D0 (en) * 2021-10-21 2021-12-08 Givaudan Sa Organic compounds

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU910561A1 (ru) * 1980-08-19 1982-03-07 Всесоюзный научно-исследовательский институт синтетических и натуральных душистых веществ Способ получени смеси душистых веществ дитерпеноидного р да
SU1498767A1 (ru) * 1987-06-04 1989-08-07 Институт Химии Ан Мсср Способ получени ( @ ) 3 @ ,6,6,9 @ -тетраметилпергидронафто [2,1-в]фурана
US5463089A (en) * 1994-07-22 1995-10-31 Quest International B.V. Preparation of ambrox
DE19524584A1 (de) * 1995-07-06 1997-01-09 Basf Ag Verfahren zur stereoselektiven Herstellung von (-)3a,6,6,9a-Tetramethyl-perhydronaphtho[2,1-b]furan
DE19649655A1 (de) 1996-11-29 1998-06-04 Haarmann & Reimer Gmbh Syntheseenzyme für die Herstellung von Coniferylalkohol, Coniferylaldehyd, Ferulasäure, Vanillin und Vanillinsäure und deren Verwendung
JP3207172B2 (ja) * 1999-01-07 2001-09-10 科学技術振興事業団 光学活性環状化合物類の製造方法
DE19960106A1 (de) 1999-12-14 2001-06-21 Haarmann & Reimer Gmbh Enzyme und Gene für die Herstellung von Vanillin
AU2003302326A1 (en) 2002-12-02 2004-08-10 The Ohio State University Research Foundation Rapid detection of microorganisms
US20040265850A1 (en) 2002-12-02 2004-12-30 Hua Wang Rapid detection of microorganisms
CN100488940C (zh) * 2004-06-11 2009-05-20 湖南中烟工业有限责任公司 用于制备降龙涎醚或向卷烟烟气释放降龙涎醚的草酸酯及应用
US8507564B2 (en) * 2005-08-04 2013-08-13 Shiseido Co., Ltd. Method for selecting perfume ingredient, method for formulating fragrance, and preference-enhancing agent
JP5236233B2 (ja) * 2007-09-04 2013-07-17 花王株式会社 （−）−アンブロキサンの製造方法
KR101752514B1 (ko) 2009-06-05 2017-06-29 바스프 에스이 소성 변형성 강성 폴리우레탄 발포체, 접착제 및 피복재를 함유하는 복합 부품
JP5735493B2 (ja) * 2009-06-05 2015-06-17 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ アンブロキサンの生物触媒的生産
EP4112727A3 (de) 2010-11-17 2023-03-15 Basf Se Verfahren zur biokatalytischen cyclisierung von terpenen und darin einsetzbare cyclase-mutanten
US8932839B2 (en) 2010-11-17 2015-01-13 Basf Se Method for the biocatalytic cyclization of terpenes and cyclase mutants employable therein
JP2013132226A (ja) 2011-12-26 2013-07-08 Kao Corp （−）−３ａ，６，６，９ａ−テトラメチルドデカヒドロナフト［２，１−ｂ］フランの製造方法
JP6226954B2 (ja) * 2012-04-16 2017-11-08 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ （３ｅ，７ｅ）−ホモファルネソールの改良製造方法
US20130273619A1 (en) * 2012-04-16 2013-10-17 Basf Se Process for the Preparation of (3E, 7E)-Homofarnesol
US9902979B2 (en) 2013-09-05 2018-02-27 Niigata University Method for producing ambrein
GB201318894D0 (en) 2013-10-25 2013-12-11 Givaudan Sa Improvements in or relating to organic compounds
GB201318886D0 (en) 2013-10-25 2013-12-11 Givaudan Sa Improvements i or relating to organic compounds
GB201507207D0 (en) * 2015-04-24 2015-06-10 Givaudan Sa Enzymes and applications thereof
CN105037308B (zh) 2015-07-06 2017-06-06 四川中烟工业有限责任公司 一种制备降龙涎香醚的方法

Also Published As

Publication number Publication date
US20180134678A1 (en) 2018-05-17
WO2016170106A1 (en) 2016-10-27
JP2018513198A (ja) 2018-05-24
BR112017021789B1 (pt) 2022-11-29
RU2017134436A3 (pt) 2019-10-09
EP3286309B1 (en) 2020-11-25
CO2017010720A2 (es) 2018-01-31
US20180346434A9 (en) 2018-12-06
GB201507170D0 (en) 2015-06-10
IL254836B2 (en) 2023-08-01
US10294211B2 (en) 2019-05-21
SG11201708085TA (en) 2017-11-29
JP2023093498A (ja) 2023-07-04
ES2856887T3 (es) 2021-09-28
JP7246133B2 (ja) 2023-03-27
EP3286309A1 (en) 2018-02-28
CN107548418B (zh) 2022-05-03
MX2017013100A (es) 2018-01-26
RU2720094C2 (ru) 2020-04-24
JP2021090423A (ja) 2021-06-17
RU2017134436A (ru) 2019-05-24
IL254836B1 (en) 2023-04-01
CN107548418A (zh) 2018-01-05
IL254836A0 (en) 2017-12-31

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Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 22/04/2016, OBSERVADAS AS CONDICOES LEGAIS