BR112017015691A2 - dispositivo e método para determinar os efeitos dos ingredientes ativos nos nematódeos e outros organismos nos testes aquosos. - Google Patents
dispositivo e método para determinar os efeitos dos ingredientes ativos nos nematódeos e outros organismos nos testes aquosos.Info
- Publication number
- BR112017015691A2 BR112017015691A2 BR112017015691-1A BR112017015691A BR112017015691A2 BR 112017015691 A2 BR112017015691 A2 BR 112017015691A2 BR 112017015691 A BR112017015691 A BR 112017015691A BR 112017015691 A2 BR112017015691 A2 BR 112017015691A2
- Authority
- BR
- Brazil
- Prior art keywords
- active ingredients
- cell culture
- culture plate
- nematodes
- organisms
- Prior art date
Links
- 239000004480 active ingredient Substances 0.000 title abstract 5
- 241000244206 Nematoda Species 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 238000012360 testing method Methods 0.000 title abstract 3
- 230000000694 effects Effects 0.000 title abstract 2
- 238000004113 cell culture Methods 0.000 abstract 6
- 230000003287 optical effect Effects 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5085—Supracellular entities, e.g. tissue, organisms of invertebrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/251—Colorimeters; Construction thereof
- G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/255—Details, e.g. use of specially adapted sources, lighting or optical systems
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T5/00—Image enhancement or restoration
- G06T5/20—Image enhancement or restoration using local operators
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/0002—Inspection of images, e.g. flaw detection
- G06T7/0012—Biomedical image inspection
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T7/00—Image analysis
- G06T7/20—Analysis of motion
- G06T7/254—Analysis of motion involving subtraction of images
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N2021/1765—Method using an image detector and processing of image signal
- G01N2021/177—Detector of the video camera type
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/063—Illuminating optical parts
- G01N2201/0638—Refractive parts
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
- G01N2333/43526—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms
- G01N2333/4353—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms from nematodes
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
- G06T2207/00—Indexing scheme for image analysis or image enhancement
- G06T2207/30—Subject of image; Context of image processing
- G06T2207/30004—Biomedical image processing
- G06T2207/30024—Cell structures in vitro; Tissue sections in vitro
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Theoretical Computer Science (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Multimedia (AREA)
- Quality & Reliability (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
dispositivo e método para determinar os efeitos dos ingredientes ativos nos nematódeos e outros organismos nos testes aquosos. a invenção refere-se a um dispositivo (1) e um método para determinar a ação dos ingredientes ativos nos nematódeos e outros organismos nos testes aquosos. o dispositivo (1), de acordo com a invenção compreende um portador (13) para uma placa de cultura celular (30) com múltiplos poços (31) nos quais os nematódeos podem ser abastecidos com os ingredientes ativos, a dita placa de cultura celular (30) com um lado inferior (33), um lado superior (32) e também paredes laterais estendendo-se entre o lado inferior (33) e o lado superior (32), uma câmera (11) que é usada para gravar imagens preferivelmente do lado inferior (33) da placa de cultura celular (30), um mecanismo de iluminação (14) com pelo menos uma primeira fonte de luz (15) que ilumina a placa de cultura celular (30), lá estando disposta, entre a primeira fonte de luz (15) e uma primeira parede lateral (34) da placa de cultura celular (30) no estado instalado, uma primeira unidade óptica que direciona a luz da primeira fonte de luz (15) através da primeira parede lateral (34) na direção do lado inferior (33) da placa de cultura celular (30). o método de acordo com a invenção torna possível simultaneamente investigar muitos ingredientes ativos dentro de um tempo muito curto.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15152272 | 2015-01-23 | ||
EP15152272.9 | 2015-01-23 | ||
PCT/EP2016/050140 WO2016116291A1 (de) | 2015-01-23 | 2016-01-06 | Verfahren und vorrichtung zur ermittlung der wirkung von wirkstoffen an nematoden und anderen organismen in wässrigen tests |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112017015691A2 true BR112017015691A2 (pt) | 2018-04-10 |
BR112017015691B1 BR112017015691B1 (pt) | 2021-06-08 |
Family
ID=52396529
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017015691-1A BR112017015691B1 (pt) | 2015-01-23 | 2016-01-06 | dispositivo e método para determinar os efeitos dos ingredientes ativos nos nematódeos e outros organismos nos testes aquosos |
Country Status (10)
Country | Link |
---|---|
US (2) | US10514375B2 (pt) |
EP (1) | EP3247990B1 (pt) |
JP (1) | JP6772150B2 (pt) |
KR (1) | KR102477339B1 (pt) |
CN (1) | CN107278268B (pt) |
AU (2) | AU2016208790A1 (pt) |
BR (1) | BR112017015691B1 (pt) |
ES (1) | ES2958398T3 (pt) |
HK (1) | HK1245883A1 (pt) |
WO (1) | WO2016116291A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3330697A1 (de) * | 2016-11-30 | 2018-06-06 | Bayer Aktiengesellschaft | Vorrichtung zur ermittlung der wirkung von wirkstoffen an nematoden und anderen organismen in wässrigen tests |
GB2578144A (en) * | 2018-10-18 | 2020-04-22 | The Univ Of Durham | Method and apparatus for tracking nematode worms |
US11492585B2 (en) * | 2019-05-31 | 2022-11-08 | Canon Medical Systems Corporation | Cell identification system and cell identification method |
WO2021173894A1 (en) * | 2020-02-28 | 2021-09-02 | Thrive Bioscience, Inc. | Pre-scan focus and scan focus methods |
Family Cites Families (26)
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JPS6170407A (ja) * | 1984-08-08 | 1986-04-11 | Canon Inc | 距離測定装置 |
WO1994005770A1 (es) | 1992-08-27 | 1994-03-17 | Iul, S.A. | Camara de contraste para realzar colonias bacterianas respecto a la base de cultivo de las mismas |
TW391139B (en) * | 1996-12-26 | 2000-05-21 | Plus Kk | Image display device |
JPH10197449A (ja) * | 1997-01-07 | 1998-07-31 | Hamamatsu Photonics Kk | 光測定装置 |
JPH11183358A (ja) * | 1997-12-25 | 1999-07-09 | Kowa Co | 蛍光粒子撮像用容器 |
JP2000074837A (ja) * | 1998-08-31 | 2000-03-14 | Fuji Photo Film Co Ltd | 撮影装置 |
GB9908676D0 (en) * | 1999-04-15 | 1999-06-09 | Devgen Nv | Method for screening compounds |
US20040101954A1 (en) * | 2002-11-27 | 2004-05-27 | Graessle Josef A. | Back side plate illumination for biological growth plate scanner |
US7265829B2 (en) | 2002-12-17 | 2007-09-04 | Molecular Devices Corporation | Reflective optic system for imaging microplate readers |
FI116946B (fi) * | 2004-07-09 | 2006-04-13 | Chip Man Technologies Oy | Laitteisto solujen kuvaamiseksi |
CN1800340A (zh) * | 2004-12-31 | 2006-07-12 | 王衍淞 | 获取培养皿内菌落图像时使用的照明方法 |
DE602005000877T2 (de) * | 2005-01-18 | 2007-12-20 | Roche Diagnostics Gmbh | Fluoreszenzabbildung mittels Telezentrizität |
US20060166305A1 (en) | 2005-01-27 | 2006-07-27 | Genetix Limited | Animal cell confluence detection method and apparatus |
JP4921458B2 (ja) * | 2005-04-04 | 2012-04-25 | ブルーシフト・バイオテクノロジーズ・インコーポレーテッド | Fret発光における偏光異方性を使用したスクリーニングの方法 |
JP4444984B2 (ja) * | 2007-04-18 | 2010-03-31 | アドバンスド・マスク・インスペクション・テクノロジー株式会社 | レチクル欠陥検査装置およびこれを用いた検査方法 |
US20100184616A1 (en) * | 2009-01-20 | 2010-07-22 | Bio-Rad Laboratories, Inc. | Spatially controlled illumination of biological sample array through wedge-shaped support |
CN102365544B (zh) * | 2009-03-26 | 2014-01-22 | 浜松光子学株式会社 | 光照射装置及光测定装置 |
JP2011059095A (ja) * | 2009-08-12 | 2011-03-24 | Sony Corp | 光検出装置 |
GB201006046D0 (en) * | 2010-04-12 | 2010-05-26 | Ge Healthcare Uk Ltd | System and method for determining motion of a biological object |
WO2011135534A2 (en) * | 2010-04-28 | 2011-11-03 | Kla-Tencor Corporation | Ring light illuminator and beam shaper for ring light illuminator |
CN102329725A (zh) * | 2010-06-16 | 2012-01-25 | 三星泰科威株式会社 | 光透射温度控制装置、生物诊断设备和方法 |
WO2012014141A1 (en) * | 2010-07-30 | 2012-02-02 | Kla-Tencor Corporation | Ring light illuminator, beam shaper and method for illumination |
KR101900121B1 (ko) * | 2011-03-04 | 2018-09-18 | 엘비티 이노베이션스 리미티드 | 이미지 캡쳐 및 조명 장치 |
US9744421B2 (en) * | 2011-06-27 | 2017-08-29 | Swing Profile Limited | Method of analysing a video of sports motion |
WO2014138203A2 (en) * | 2013-03-05 | 2014-09-12 | Board Of Regents, The University Of Texas System | Microfluidic devices for the rapid and automated processing of sample populations |
RU2745751C2 (ru) * | 2015-02-27 | 2021-03-31 | Сфинготек Гмбх | Способ прогнозирования риска развития ожирения у субъекта |
-
2016
- 2016-01-06 JP JP2017538697A patent/JP6772150B2/ja active Active
- 2016-01-06 WO PCT/EP2016/050140 patent/WO2016116291A1/de active Application Filing
- 2016-01-06 ES ES16700534T patent/ES2958398T3/es active Active
- 2016-01-06 KR KR1020177021842A patent/KR102477339B1/ko not_active Application Discontinuation
- 2016-01-06 US US15/544,409 patent/US10514375B2/en active Active
- 2016-01-06 EP EP16700534.7A patent/EP3247990B1/de active Active
- 2016-01-06 BR BR112017015691-1A patent/BR112017015691B1/pt active IP Right Grant
- 2016-01-06 AU AU2016208790A patent/AU2016208790A1/en not_active Abandoned
- 2016-01-06 CN CN201680006689.6A patent/CN107278268B/zh active Active
-
2018
- 2018-04-18 HK HK18105001.6A patent/HK1245883A1/zh unknown
-
2019
- 2019-11-13 US US16/682,666 patent/US10948481B2/en active Active
-
2021
- 2021-06-22 AU AU2021204224A patent/AU2021204224B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
BR112017015691B1 (pt) | 2021-06-08 |
JP6772150B2 (ja) | 2020-10-21 |
US10948481B2 (en) | 2021-03-16 |
KR20170103872A (ko) | 2017-09-13 |
EP3247990A1 (de) | 2017-11-29 |
US20180011084A1 (en) | 2018-01-11 |
HK1245883A1 (zh) | 2018-08-31 |
ES2958398T3 (es) | 2024-02-08 |
AU2021204224A1 (en) | 2021-07-15 |
WO2016116291A1 (de) | 2016-07-28 |
CN107278268A (zh) | 2017-10-20 |
AU2016208790A1 (en) | 2017-08-10 |
EP3247990B1 (de) | 2023-07-05 |
CN107278268B (zh) | 2022-02-08 |
JP2018503097A (ja) | 2018-02-01 |
AU2021204224B2 (en) | 2023-07-13 |
KR102477339B1 (ko) | 2022-12-14 |
US10514375B2 (en) | 2019-12-24 |
US20200080992A1 (en) | 2020-03-12 |
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Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 06/01/2016, OBSERVADAS AS CONDICOES LEGAIS. |