BR112017002527A2 - revestimentos de artigos incluindo camada de polifenol oligomerizado e métodos biológicos de uso - Google Patents

revestimentos de artigos incluindo camada de polifenol oligomerizado e métodos biológicos de uso

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Publication number
BR112017002527A2
BR112017002527A2 BR112017002527A BR112017002527A BR112017002527A2 BR 112017002527 A2 BR112017002527 A2 BR 112017002527A2 BR 112017002527 A BR112017002527 A BR 112017002527A BR 112017002527 A BR112017002527 A BR 112017002527A BR 112017002527 A2 BR112017002527 A2 BR 112017002527A2
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BR
Brazil
Prior art keywords
layer
oligomerized polyphenol
polyphenol layer
medical device
biological methods
Prior art date
Application number
BR112017002527A
Other languages
English (en)
Other versions
BR112017002527B1 (pt
Inventor
Torguson Adriyn
e babcock David
Opperman Gary
lundquist Sean
Jentz Tim
Original Assignee
Surmodics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Surmodics Inc filed Critical Surmodics Inc
Publication of BR112017002527A2 publication Critical patent/BR112017002527A2/pt
Publication of BR112017002527B1 publication Critical patent/BR112017002527B1/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024—Esters of saccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/04—Macromolecular materials
    • A61L29/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L29/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers
    • C08L29/02—Homopolymers or copolymers of unsaturated alcohols
    • C08L29/04—Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/216—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding
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    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
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    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/02—Methods for coating medical devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/08—Coatings comprising two or more layers

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  • Life Sciences & Earth Sciences (AREA)
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  • Dermatology (AREA)
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Abstract

resumo "revestimentos de artigos incluindo camada de polifenol oligomerizado e métodos biológicos de uso" modalidades da revelação incluem revestimentos compreendendo uma camada de polifenol oligomerizado. a camada de polifenol oligomerizado pode ser utilizada como uma camada revestida intermediária em um dispositivo médico que hidrogênio liga a um polímero sintético ou natural, que por sua vez pode ser utilizado como um revestimento superior ou ainda associado com outra camada revestida. os revestimentos multicamadas podem prover propriedades tal como hemocompatibilidade ou lubricidade. em outras modalidades, a camada de polifenol oligomerizado é utilizada em um dispositivo médico como uma camada hemostática configurada para entrar em contato com o sangue e promover coagulação. a camada de polifenol oligomerizado pode também ser utilizada na superfície interna (por exemplo, diâmetro interno) de um dispositivo médico para prevenir aderência bacteriana. a camada de polifenol oligomerizado pode também ser utilizada na superfície de um artigo diagnóstico in vitro, ou um dispositivo de cultura celular para promover adsorção de uma molécula biológica.
BR112017002527-2A 2014-08-08 2015-08-06 Dispositivo médico, método para revestimento de um dispositivo médico, método para promoção de coagulação em uma localização alvo no ou sobre o corpo, artigo configurado para uso em um ensaio diagnóstico in vitro ou cultura celular, kit diagnóstico, método para promover adsorção de uma macromolécula biológica a uma superfície de um artigo em um ensaio diagnóstico in vitro ou cultura celular e método para reduzir ou prevenir a aderência de bactéria em uma superfície de dispositivo médico BR112017002527B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462035173P 2014-08-08 2014-08-08
US62/035.173 2014-08-08
PCT/US2015/044002 WO2016022796A1 (en) 2014-08-08 2015-08-06 Article coatings including oligomerized polyphenol layer and biological methods of use

Publications (2)

Publication Number Publication Date
BR112017002527A2 true BR112017002527A2 (pt) 2017-12-05
BR112017002527B1 BR112017002527B1 (pt) 2021-03-23

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BR112017002527-2A BR112017002527B1 (pt) 2014-08-08 2015-08-06 Dispositivo médico, método para revestimento de um dispositivo médico, método para promoção de coagulação em uma localização alvo no ou sobre o corpo, artigo configurado para uso em um ensaio diagnóstico in vitro ou cultura celular, kit diagnóstico, método para promover adsorção de uma macromolécula biológica a uma superfície de um artigo em um ensaio diagnóstico in vitro ou cultura celular e método para reduzir ou prevenir a aderência de bactéria em uma superfície de dispositivo médico

Country Status (9)

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US (2) US10201637B2 (pt)
EP (1) EP3177332B1 (pt)
JP (1) JP6650436B2 (pt)
CN (1) CN106794283B (pt)
BR (1) BR112017002527B1 (pt)
CA (1) CA2956721C (pt)
MX (1) MX2017001626A (pt)
RU (1) RU2711535C2 (pt)
WO (1) WO2016022796A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3303473B1 (en) * 2015-05-26 2020-05-13 The University Of British Columbia Antifouling polymeric coating compositions
EP3682238A4 (en) 2017-09-14 2020-12-16 Siemens Healthcare Diagnostics Inc. MEMBRANES CONTAINING AN ADHESIVE POLYMER FOR IN VITRO DIAGNOSTIC DEVICES
WO2019222007A1 (en) * 2018-05-14 2019-11-21 The Penn State Research Foundation Slippery surfaces on common substrates
EP3793450B1 (en) * 2018-05-15 2024-06-26 Boston Scientific Scimed, Inc. Occlusive medical device with charged polymer coating
CN110354295B (zh) * 2019-05-17 2021-12-07 四川大学 一种光热转换材料及其制备方法
KR20220049558A (ko) * 2019-08-20 2022-04-21 더 리젠츠 오브 더 유니버시티 오브 미시간 표면 관능화 기재 및 이의 제조 방법
CN114466668A (zh) 2019-09-27 2022-05-10 巴德血管外围设备公司 用于确定血液中的细菌感染的涂覆有抗体的医疗装置
CN110652612B (zh) * 2019-10-22 2021-12-14 四川大学 一种简易聚合物分子刷涂层的制备方法
CN111450315A (zh) * 2020-04-23 2020-07-28 东华大学 一种抑炎水凝胶涂覆聚丙烯补片及其制备方法
CN112816688B (zh) * 2021-01-04 2022-05-13 深圳市柏明胜医疗器械有限公司 一种酶标板及其制备方法和应用
CN113069588B (zh) * 2021-04-17 2022-04-22 北京化工大学 一种多酚金属离子促凝涂层在制备止血材料上的应用
CN113559720B (zh) * 2021-07-12 2022-08-05 武汉理工大学 拥有仿肝素改性涂层的聚醚砜血液透析膜及其制备方法、应用
CN114404672B (zh) * 2022-01-19 2023-03-03 四川大学 一种联合多酚和抗菌肽的纤维膜及其制备方法和应用
CN114767918B (zh) * 2022-03-21 2023-04-07 东莞市人民医院 一种促凝止血蛋白材料、促凝止血抗菌材料及其制备方法
CN114939185B (zh) * 2022-05-19 2023-03-24 北京化工大学 一种阳离子化多糖多酚复合止血涂层的制备方法
CN115414539B (zh) * 2022-09-02 2023-12-15 北京化工大学 一种多酚-聚合物涂层的制备方法及其在增强材料促凝血性能中的应用
CN115429941B (zh) * 2022-09-02 2024-05-28 北京化工大学 一种差异化黏附蛋白的多酚-聚合物功能涂层的制备方法及应用
WO2024045163A1 (zh) * 2022-09-02 2024-03-07 北京化工大学 一种多酚-聚合物复合涂层的制备方法及其在医用材料功能化中的应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5512329A (en) 1982-09-29 1996-04-30 Bsi Corporation Substrate surface preparation
US5002582A (en) 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
US4979959A (en) 1986-10-17 1990-12-25 Bio-Metric Systems, Inc. Biocompatible coating for solid surfaces
US5263992A (en) 1986-10-17 1993-11-23 Bio-Metric Systems, Inc. Biocompatible device with covalently bonded biocompatible agent
US5135516A (en) * 1989-12-15 1992-08-04 Boston Scientific Corporation Lubricious antithrombogenic catheters, guidewires and coatings
US5414075A (en) 1992-11-06 1995-05-09 Bsi Corporation Restrained multifunctional reagent for surface modification
US5714360A (en) 1995-11-03 1998-02-03 Bsi Corporation Photoactivatable water soluble cross-linking agents containing an onium group
US5858653A (en) 1997-09-30 1999-01-12 Surmodics, Inc. Reagent and method for attaching target molecules to a surface
US6007833A (en) 1998-03-19 1999-12-28 Surmodics, Inc. Crosslinkable macromers bearing initiator groups
US6278018B1 (en) 1999-12-14 2001-08-21 Surmodics, Inc. Surface coating agents
US8105666B2 (en) * 2005-03-15 2012-01-31 Finley Michael J Compliant polymeric coatings for insertable medical articles
US20070282422A1 (en) * 2006-05-10 2007-12-06 Cook Incorporated Medical devices and methods for local delivery of elastin-stabilizing compounds
US8414910B2 (en) * 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
JP4987531B2 (ja) * 2007-03-27 2012-07-25 日本ライフライン株式会社 医療用ガイドワイヤおよびその製造方法
US8465587B2 (en) * 2009-12-30 2013-06-18 Cbl Technologies, Inc. Modern hydride vapor-phase epitaxy system and methods
BR112012024244B8 (pt) * 2010-03-25 2021-06-22 Lutonix Inc catéter de balão para administração de fármaco em um tecido
BR112012024919B1 (pt) 2010-03-30 2019-01-02 Surmodics Inc agente ligante degradável, método de revestir uma superfície de suporte com um agente ligante para prover a superfície com um ou mais grupos reativos latentes, superfície de suporte e dispositivo médico revestido
JP5692844B2 (ja) 2010-09-24 2015-04-01 高砂香料工業株式会社 スルフィド類用消臭剤組成物
EP2709711B8 (en) 2011-05-18 2017-03-22 Vatrix Medical, Inc. Coated balloons for blood vessel stabilization
EP2941279B1 (en) * 2013-01-04 2023-05-17 SurModics, Inc. Low particulate lubricious coating with vinyl pyrrolidone and acidic polymer-containing layers

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US20190275209A1 (en) 2019-09-12
JP6650436B2 (ja) 2020-02-19
BR112017002527B1 (pt) 2021-03-23
RU2017107413A3 (pt) 2018-09-11
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MX2017001626A (es) 2017-05-09
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