MX2017001626A - Recubrimientos de articulo que incluyen capa de polifenol oligomerizado y metodos biologicos de uso. - Google Patents

Recubrimientos de articulo que incluyen capa de polifenol oligomerizado y metodos biologicos de uso.

Info

Publication number
MX2017001626A
MX2017001626A MX2017001626A MX2017001626A MX2017001626A MX 2017001626 A MX2017001626 A MX 2017001626A MX 2017001626 A MX2017001626 A MX 2017001626A MX 2017001626 A MX2017001626 A MX 2017001626A MX 2017001626 A MX2017001626 A MX 2017001626A
Authority
MX
Mexico
Prior art keywords
layer
oligomerized polyphenol
polyphenol layer
medical device
biological methods
Prior art date
Application number
MX2017001626A
Other languages
English (en)
Inventor
e babcock David
lundquist Sean
Opperman Gary
Torguson Adriyn
Jentz Tim
Original Assignee
Surmodics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Surmodics Inc filed Critical Surmodics Inc
Publication of MX2017001626A publication Critical patent/MX2017001626A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7024—Esters of saccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/04—Macromolecular materials
    • A61L29/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L29/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers
    • C08L29/02—Homopolymers or copolymers of unsaturated alcohols
    • C08L29/04—Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/216—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/02—Methods for coating medical devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/08—Coatings comprising two or more layers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Materials Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)

Abstract

Las modalidades de la descripción incluyen recubrimientos que comprenden una capa de polifenol oligomerizado. La capa de polifenol oligomerizado puede ser utilizada como una capa recubierta intermedia en un dispositivo médico que los enlaces de hidrógeno a un polímero sintético o natural, que a su vez puede ser utilizado como una capa superior o además asociada con otra capa de revestimiento. Los recubrimientos de múltiples capas pueden proporcionar propiedades tales como hemocompatibilidad o lubricidad. En otras modalidades, la capa de polifenol oligomerizado se usa en un dispositivo médico como una capa hemostática configurada para ponerse en contacto con la sangre y promover la coagulación. La capa de polifenol oligomerizado también se puede utilizar en la superficie interior (por ejemplo, diámetro interno) de un dispositivo médico para evitar la adherencia bacteriana. La capa de polifenol oligomerizado también se puede utilizar en la superficie de un artículo de diagnóstico in vitro, o un dispositivo de cultivo celular para, promover la adsorción de una molécula biológica.
MX2017001626A 2014-08-08 2015-08-06 Recubrimientos de articulo que incluyen capa de polifenol oligomerizado y metodos biologicos de uso. MX2017001626A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462035173P 2014-08-08 2014-08-08
PCT/US2015/044002 WO2016022796A1 (en) 2014-08-08 2015-08-06 Article coatings including oligomerized polyphenol layer and biological methods of use

Publications (1)

Publication Number Publication Date
MX2017001626A true MX2017001626A (es) 2017-05-09

Family

ID=54011885

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017001626A MX2017001626A (es) 2014-08-08 2015-08-06 Recubrimientos de articulo que incluyen capa de polifenol oligomerizado y metodos biologicos de uso.

Country Status (9)

Country Link
US (2) US10201637B2 (es)
EP (1) EP3177332B1 (es)
JP (1) JP6650436B2 (es)
CN (1) CN106794283B (es)
BR (1) BR112017002527B1 (es)
CA (1) CA2956721C (es)
MX (1) MX2017001626A (es)
RU (1) RU2711535C2 (es)
WO (1) WO2016022796A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11459434B2 (en) 2015-05-26 2022-10-04 The University Of British Columbia Antifouling polymeric coating compositions
CA3075743C (en) 2017-09-14 2023-02-28 Siemens Healthcare Diagnostics Inc. Adhesive-polymer containing membranes for in vitro diagnostic devices
CA3098872A1 (en) * 2018-05-14 2019-11-21 The Penn State Research Foundation Slippery surfaces on common substrates
US11241239B2 (en) * 2018-05-15 2022-02-08 Boston Scientific Scimed, Inc. Occlusive medical device with charged polymer coating
CN110354295B (zh) * 2019-05-17 2021-12-07 四川大学 一种光热转换材料及其制备方法
KR20220049558A (ko) * 2019-08-20 2022-04-21 더 리젠츠 오브 더 유니버시티 오브 미시간 표면 관능화 기재 및 이의 제조 방법
EP4028076A1 (en) 2019-09-27 2022-07-20 Bard Peripheral Vascular, Inc. Medical devices coated with antibodies for determining bacterial infections in blood
CN110652612B (zh) * 2019-10-22 2021-12-14 四川大学 一种简易聚合物分子刷涂层的制备方法
CN111450315A (zh) * 2020-04-23 2020-07-28 东华大学 一种抑炎水凝胶涂覆聚丙烯补片及其制备方法
CN112816688B (zh) * 2021-01-04 2022-05-13 深圳市柏明胜医疗器械有限公司 一种酶标板及其制备方法和应用
CN113069588B (zh) * 2021-04-17 2022-04-22 北京化工大学 一种多酚金属离子促凝涂层在制备止血材料上的应用
CN113559720B (zh) * 2021-07-12 2022-08-05 武汉理工大学 拥有仿肝素改性涂层的聚醚砜血液透析膜及其制备方法、应用
CN114404672B (zh) * 2022-01-19 2023-03-03 四川大学 一种联合多酚和抗菌肽的纤维膜及其制备方法和应用
CN114767918B (zh) * 2022-03-21 2023-04-07 东莞市人民医院 一种促凝止血蛋白材料、促凝止血抗菌材料及其制备方法
CN114939185B (zh) * 2022-05-19 2023-03-24 北京化工大学 一种阳离子化多糖多酚复合止血涂层的制备方法
CN115414539B (zh) * 2022-09-02 2023-12-15 北京化工大学 一种多酚-聚合物涂层的制备方法及其在增强材料促凝血性能中的应用
WO2024045163A1 (zh) * 2022-09-02 2024-03-07 北京化工大学 一种多酚-聚合物复合涂层的制备方法及其在医用材料功能化中的应用
CN115429941B (zh) * 2022-09-02 2024-05-28 北京化工大学 一种差异化黏附蛋白的多酚-聚合物功能涂层的制备方法及应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002582A (en) 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
US5512329A (en) 1982-09-29 1996-04-30 Bsi Corporation Substrate surface preparation
US5263992A (en) 1986-10-17 1993-11-23 Bio-Metric Systems, Inc. Biocompatible device with covalently bonded biocompatible agent
US4979959A (en) 1986-10-17 1990-12-25 Bio-Metric Systems, Inc. Biocompatible coating for solid surfaces
US5135516A (en) * 1989-12-15 1992-08-04 Boston Scientific Corporation Lubricious antithrombogenic catheters, guidewires and coatings
US5414075A (en) 1992-11-06 1995-05-09 Bsi Corporation Restrained multifunctional reagent for surface modification
US5714360A (en) 1995-11-03 1998-02-03 Bsi Corporation Photoactivatable water soluble cross-linking agents containing an onium group
US5858653A (en) 1997-09-30 1999-01-12 Surmodics, Inc. Reagent and method for attaching target molecules to a surface
US6007833A (en) 1998-03-19 1999-12-28 Surmodics, Inc. Crosslinkable macromers bearing initiator groups
US6278018B1 (en) 1999-12-14 2001-08-21 Surmodics, Inc. Surface coating agents
CA2600711C (en) * 2005-03-15 2014-07-08 Surmodics, Inc. Compliant polymeric coatings for insertable medical articles
US20070282422A1 (en) * 2006-05-10 2007-12-06 Cook Incorporated Medical devices and methods for local delivery of elastin-stabilizing compounds
US8414910B2 (en) * 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
JP4987531B2 (ja) * 2007-03-27 2012-07-25 日本ライフライン株式会社 医療用ガイドワイヤおよびその製造方法
US8465587B2 (en) * 2009-12-30 2013-06-18 Cbl Technologies, Inc. Modern hydride vapor-phase epitaxy system and methods
CN102883753B (zh) * 2010-03-25 2015-04-15 路通医疗股份有限公司 用于医疗设备的释药涂层
CN102869671B (zh) 2010-03-30 2019-04-16 苏尔莫迪克斯公司 可降解的光交联剂
JP5692844B2 (ja) 2010-09-24 2015-04-01 高砂香料工業株式会社 スルフィド類用消臭剤組成物
JP2014516695A (ja) * 2011-05-18 2014-07-17 バトリックス・メディカル・インコーポレイテッド 血管安定化用被覆バルーン
EP4276161A3 (en) * 2013-01-04 2024-01-17 SurModics, Inc. Low particulate lubricious coating with vinyl pyrrolidone and acidic polymer-containing layers

Also Published As

Publication number Publication date
BR112017002527A2 (pt) 2017-12-05
CA2956721C (en) 2023-09-12
WO2016022796A1 (en) 2016-02-11
EP3177332B1 (en) 2021-06-30
CN106794283A (zh) 2017-05-31
JP2017525458A (ja) 2017-09-07
EP3177332A1 (en) 2017-06-14
BR112017002527B1 (pt) 2021-03-23
US20170224876A1 (en) 2017-08-10
US20190275209A1 (en) 2019-09-12
US11938250B2 (en) 2024-03-26
CA2956721A1 (en) 2016-02-11
JP6650436B2 (ja) 2020-02-19
RU2711535C2 (ru) 2020-01-17
CN106794283B (zh) 2021-03-02
RU2017107413A3 (es) 2018-09-11
US10201637B2 (en) 2019-02-12
RU2017107413A (ru) 2018-09-11

Similar Documents

Publication Publication Date Title
MX2017001626A (es) Recubrimientos de articulo que incluyen capa de polifenol oligomerizado y metodos biologicos de uso.
MX340253B (es) Recubrimiento de aguja quirúrgica y métodos.
CR20150531A (es) Válvula de endoprótesis vascular con comisura y métodos
CR20160240A (es) Sistemas y métodos para la manufactura del marco de una cánula
WO2012100100A3 (en) Slippery liquid-infused porous surfaces and biological applications thereof
MX2021013881A (es) Obturador antimicrobiano para usarse con dispositivos de acceso vascular.
WO2017163132A3 (en) Use of umbilical cord blood derived exosomes for tissue repair
EP3885394A3 (en) Surface disinfectant with residual biocidal property
BR112015002154A2 (pt) curativo de ferimento
EP2597947A4 (en) COMPOSITION FOR PRESERVING PLATES AND METHOD OF USE THEREOF
BR112012011000A2 (pt) revestimentos e métodos de revestimento de agulhas cirúrgicas
TR201905882T4 (tr) Dağıtım aparatı.
WO2009017924A3 (en) Drug eluting implantable medical device with hemocompatible and/or prohealing topcoat
EP4276161A3 (en) Low particulate lubricious coating with vinyl pyrrolidone and acidic polymer-containing layers
BR112012022440A2 (pt) dispositivo médico, método para revestir um balão de catéter e balão de catéter revestido com ou sem um stent
EA201490509A1 (ru) Биосовместимый катетер
BR112012010994A2 (pt) revestimentos e métodos de revestimento de agulhas cirúrgicas
BR112016024798A2 (pt) tubo de cateter com revestimento antimicrobiano extraluminal
MX2016009865A (es) Pelicula rigida de nanocompuesto para su uso en un articulo absorbente.
EP3285798A4 (en) Fibroblast growth factor (fgf) 1 with mutation in the heparin binding domain and methods of use to reduce blood glucose
BR112013001918A2 (pt) sirna direcionado para vegfa e métodos para tratamento in vivo
EP3541265A4 (en) DEVICES, SYSTEMS AND METHODS FOR IN VIVO CLEANING THE SURFACE OF A MEDICAL INSTRUMENT
BR112013021661A2 (pt) objetivação de fator de coagulação a tlt-1 sobre plaquetas ativadas
EP3279308A4 (en) Medical instrument, fluorinated cyclic olefin polymer, fluorinated cyclic olefin polymer composition, and cell culture method
IN2013MU02532A (es)