BR112016029413A2 - utilização de inibidores peptídicos permeáveis às células da via de transdução do sinal da jnk para o tratamento de várias doenças - Google Patents
utilização de inibidores peptídicos permeáveis às células da via de transdução do sinal da jnk para o tratamento de várias doençasInfo
- Publication number
- BR112016029413A2 BR112016029413A2 BR112016029413A BR112016029413A BR112016029413A2 BR 112016029413 A2 BR112016029413 A2 BR 112016029413A2 BR 112016029413 A BR112016029413 A BR 112016029413A BR 112016029413 A BR112016029413 A BR 112016029413A BR 112016029413 A2 BR112016029413 A2 BR 112016029413A2
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- various diseases
- cell
- signal transduction
- transduction pathway
- Prior art date
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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Abstract
a presente invenção se refere à utilização de inibidores de proteína qiinases e mais especificamente à utilização de inibidores da proteína qiinase c-jun amino terminal quinase, sequências de inibidores da jnk, de peptídeos quiméricos, ou de ácidos nucléicos codificando para os mesmos bem como a composições farmacêuticas contendo os mesmos, para o tratamento de várias doenças ou distúrbios fortemente relacionados com a sinalização da jnk.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2013/001881 WO2014206427A1 (en) | 2013-06-26 | 2013-06-26 | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
EP2013001896 | 2013-06-27 | ||
PCT/EP2014/001736 WO2014206563A2 (en) | 2013-06-26 | 2014-06-26 | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
PCT/EP2014/002724 WO2015197098A1 (en) | 2014-06-26 | 2014-10-08 | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
PCT/EP2015/001294 WO2015197194A2 (en) | 2014-06-26 | 2015-06-26 | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112016029413A2 true BR112016029413A2 (pt) | 2017-10-17 |
Family
ID=51033122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016029413A BR112016029413A2 (pt) | 2013-06-26 | 2015-06-26 | utilização de inibidores peptídicos permeáveis às células da via de transdução do sinal da jnk para o tratamento de várias doenças |
Country Status (14)
Country | Link |
---|---|
US (1) | US10624948B2 (pt) |
EP (1) | EP3013353B1 (pt) |
JP (3) | JP2016523274A (pt) |
KR (1) | KR20160023669A (pt) |
CN (1) | CN105307670A (pt) |
AU (1) | AU2014301631A1 (pt) |
BR (1) | BR112016029413A2 (pt) |
CA (1) | CA2903275A1 (pt) |
EA (1) | EA201501080A1 (pt) |
ES (1) | ES2870085T3 (pt) |
HK (1) | HK1224225A1 (pt) |
MX (1) | MX2016017308A (pt) |
PL (1) | PL3013353T3 (pt) |
WO (1) | WO2014206563A2 (pt) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5857056B2 (ja) | 2010-10-14 | 2016-02-10 | ザイジェン インフラメーション エルティーディー | 慢性又は非慢性の炎症性眼疾患を治療するためのjnkシグナル伝達経路の細胞透過性ペプチド阻害剤の使用 |
WO2013091670A1 (en) | 2011-12-21 | 2013-06-27 | Xigen S.A. | Novel jnk inhibitor molecules for treatment of various diseases |
JP2016523274A (ja) | 2013-06-26 | 2016-08-08 | ザイジェン インフラメーション リミテッド | 種々の疾患を処置するためのjnkシグナル伝達経路の新規の細胞透過性ペプチド阻害剤の使用 |
WO2015197097A1 (en) | 2014-06-26 | 2015-12-30 | Xigen Inflammation Ltd. | New use for jnk inhibitor molecules for treatment of various diseases |
WO2014206426A1 (en) * | 2013-06-26 | 2014-12-31 | Xigen Inflammation Ltd. | New use for jnk inhibitor molecules for treatment of various diseases |
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JP2015197193A (ja) | 2014-04-02 | 2015-11-09 | トヨタ自動車株式会社 | 車両用無段変速機の油圧制御装置 |
CN107969126A (zh) | 2015-06-26 | 2018-04-27 | 埃克西金炎症有限公司 | Jnk信号转导通路的细胞穿透肽抑制剂用于治疗轻度认知损害的新用途 |
-
2014
- 2014-06-26 JP JP2016522321A patent/JP2016523274A/ja not_active Withdrawn
- 2014-06-26 CN CN201480030666.XA patent/CN105307670A/zh active Pending
- 2014-06-26 US US14/891,067 patent/US10624948B2/en active Active
- 2014-06-26 PL PL14734003T patent/PL3013353T3/pl unknown
- 2014-06-26 CA CA2903275A patent/CA2903275A1/en not_active Abandoned
- 2014-06-26 AU AU2014301631A patent/AU2014301631A1/en not_active Abandoned
- 2014-06-26 WO PCT/EP2014/001736 patent/WO2014206563A2/en active Application Filing
- 2014-06-26 EA EA201501080A patent/EA201501080A1/ru unknown
- 2014-06-26 ES ES14734003T patent/ES2870085T3/es active Active
- 2014-06-26 KR KR1020157034160A patent/KR20160023669A/ko not_active Application Discontinuation
- 2014-06-26 EP EP14734003.8A patent/EP3013353B1/en active Active
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2015
- 2015-06-26 JP JP2016575155A patent/JP2017520571A/ja not_active Withdrawn
- 2015-06-26 BR BR112016029413A patent/BR112016029413A2/pt not_active IP Right Cessation
- 2015-06-26 MX MX2016017308A patent/MX2016017308A/es unknown
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2016
- 2016-11-03 HK HK16112683.9A patent/HK1224225A1/zh unknown
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2019
- 2019-12-17 JP JP2019226998A patent/JP2020055866A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3013353B1 (en) | 2021-04-21 |
ES2870085T3 (es) | 2021-10-26 |
AU2014301631A1 (en) | 2015-08-27 |
JP2017520571A (ja) | 2017-07-27 |
MX2016017308A (es) | 2017-05-01 |
WO2014206563A3 (en) | 2015-03-19 |
US20160199444A1 (en) | 2016-07-14 |
JP2020055866A (ja) | 2020-04-09 |
US10624948B2 (en) | 2020-04-21 |
WO2014206563A2 (en) | 2014-12-31 |
EP3013353A2 (en) | 2016-05-04 |
EA201501080A1 (ru) | 2016-07-29 |
JP2016523274A (ja) | 2016-08-08 |
CN105307670A (zh) | 2016-02-03 |
CA2903275A1 (en) | 2014-12-31 |
HK1224225A1 (zh) | 2017-08-18 |
PL3013353T3 (pl) | 2021-09-20 |
KR20160023669A (ko) | 2016-03-03 |
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