BR112016029413A2 - utilização de inibidores peptídicos permeáveis às células da via de transdução do sinal da jnk para o tratamento de várias doenças - Google Patents
utilização de inibidores peptídicos permeáveis às células da via de transdução do sinal da jnk para o tratamento de várias doençasInfo
- Publication number
- BR112016029413A2 BR112016029413A2 BR112016029413A BR112016029413A BR112016029413A2 BR 112016029413 A2 BR112016029413 A2 BR 112016029413A2 BR 112016029413 A BR112016029413 A BR 112016029413A BR 112016029413 A BR112016029413 A BR 112016029413A BR 112016029413 A2 BR112016029413 A2 BR 112016029413A2
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- various diseases
- cell
- signal transduction
- transduction pathway
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 230000019491 signal transduction Effects 0.000 title 1
- 229940045988 antineoplastic drug protein kinase inhibitors Drugs 0.000 abstract 3
- 239000003909 protein kinase inhibitor Substances 0.000 abstract 3
- 108010055717 JNK Mitogen-Activated Protein Kinases Proteins 0.000 abstract 1
- 229940118135 JNK inhibitor Drugs 0.000 abstract 1
- 239000012825 JNK inhibitor Substances 0.000 abstract 1
- 108091006116 chimeric peptides Proteins 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000011664 signaling Effects 0.000 abstract 1
Classifications
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Marine Sciences & Fisheries (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2013/001881 WO2014206427A1 (en) | 2013-06-26 | 2013-06-26 | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
| EP2013001896 | 2013-06-27 | ||
| PCT/EP2014/001736 WO2014206563A2 (en) | 2013-06-26 | 2014-06-26 | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
| PCT/EP2014/002724 WO2015197098A1 (en) | 2014-06-26 | 2014-10-08 | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
| PCT/EP2015/001294 WO2015197194A2 (en) | 2014-06-26 | 2015-06-26 | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112016029413A2 true BR112016029413A2 (pt) | 2017-10-17 |
Family
ID=51033122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112016029413A BR112016029413A2 (pt) | 2013-06-26 | 2015-06-26 | utilização de inibidores peptídicos permeáveis às células da via de transdução do sinal da jnk para o tratamento de várias doenças |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10624948B2 (enExample) |
| EP (1) | EP3013353B1 (enExample) |
| JP (3) | JP2016523274A (enExample) |
| KR (1) | KR20160023669A (enExample) |
| CN (1) | CN105307670A (enExample) |
| AU (1) | AU2014301631A1 (enExample) |
| BR (1) | BR112016029413A2 (enExample) |
| CA (1) | CA2903275A1 (enExample) |
| EA (1) | EA201501080A1 (enExample) |
| ES (1) | ES2870085T3 (enExample) |
| HK (1) | HK1224225A1 (enExample) |
| MX (1) | MX2016017308A (enExample) |
| PL (1) | PL3013353T3 (enExample) |
| WO (1) | WO2014206563A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010362444B2 (en) | 2010-10-14 | 2015-08-06 | Xigen Inflammation Ltd. | Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of chronic or non-chronic inflammatory eye diseases |
| WO2013091670A1 (en) | 2011-12-21 | 2013-06-27 | Xigen S.A. | Novel jnk inhibitor molecules for treatment of various diseases |
| EA201501080A1 (ru) | 2013-06-26 | 2016-07-29 | Ксижен Инфлемейшн Лтд. | Новое применение обладающих способностью проникать в клетку пептидных ингибиторов пути трансдукции сигнала jnk для лечения различных заболеваний |
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| WO2013091670A1 (en) | 2011-12-21 | 2013-06-27 | Xigen S.A. | Novel jnk inhibitor molecules for treatment of various diseases |
| EA201501080A1 (ru) | 2013-06-26 | 2016-07-29 | Ксижен Инфлемейшн Лтд. | Новое применение обладающих способностью проникать в клетку пептидных ингибиторов пути трансдукции сигнала jnk для лечения различных заболеваний |
| WO2014206427A1 (en) | 2013-06-26 | 2014-12-31 | Xigen Inflammation Ltd. | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
| WO2014206426A1 (en) | 2013-06-26 | 2014-12-31 | Xigen Inflammation Ltd. | New use for jnk inhibitor molecules for treatment of various diseases |
| WO2015197193A2 (en) | 2014-06-26 | 2015-12-30 | Xigen Inflammation Ltd. | New use for jnk inhibitor molecules for treatment of various diseases |
| JP2015197193A (ja) | 2014-04-02 | 2015-11-09 | トヨタ自動車株式会社 | 車両用無段変速機の油圧制御装置 |
| EP3313428A1 (en) | 2015-06-26 | 2018-05-02 | Xigen Inflammation Ltd. | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of mild cognitive impairment |
-
2014
- 2014-06-26 EA EA201501080A patent/EA201501080A1/ru unknown
- 2014-06-26 CA CA2903275A patent/CA2903275A1/en not_active Abandoned
- 2014-06-26 ES ES14734003T patent/ES2870085T3/es active Active
- 2014-06-26 AU AU2014301631A patent/AU2014301631A1/en not_active Abandoned
- 2014-06-26 CN CN201480030666.XA patent/CN105307670A/zh active Pending
- 2014-06-26 US US14/891,067 patent/US10624948B2/en active Active
- 2014-06-26 PL PL14734003T patent/PL3013353T3/pl unknown
- 2014-06-26 EP EP14734003.8A patent/EP3013353B1/en active Active
- 2014-06-26 JP JP2016522321A patent/JP2016523274A/ja not_active Withdrawn
- 2014-06-26 WO PCT/EP2014/001736 patent/WO2014206563A2/en not_active Ceased
- 2014-06-26 HK HK16112683.9A patent/HK1224225A1/zh unknown
- 2014-06-26 KR KR1020157034160A patent/KR20160023669A/ko not_active Withdrawn
-
2015
- 2015-06-26 JP JP2016575155A patent/JP2017520571A/ja not_active Withdrawn
- 2015-06-26 BR BR112016029413A patent/BR112016029413A2/pt not_active IP Right Cessation
- 2015-06-26 MX MX2016017308A patent/MX2016017308A/es unknown
-
2019
- 2019-12-17 JP JP2019226998A patent/JP2020055866A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2014301631A1 (en) | 2015-08-27 |
| US10624948B2 (en) | 2020-04-21 |
| WO2014206563A2 (en) | 2014-12-31 |
| ES2870085T3 (es) | 2021-10-26 |
| MX2016017308A (es) | 2017-05-01 |
| EP3013353B1 (en) | 2021-04-21 |
| EA201501080A1 (ru) | 2016-07-29 |
| KR20160023669A (ko) | 2016-03-03 |
| WO2014206563A3 (en) | 2015-03-19 |
| JP2016523274A (ja) | 2016-08-08 |
| US20160199444A1 (en) | 2016-07-14 |
| CA2903275A1 (en) | 2014-12-31 |
| CN105307670A (zh) | 2016-02-03 |
| JP2017520571A (ja) | 2017-07-27 |
| PL3013353T3 (pl) | 2021-09-20 |
| HK1224225A1 (zh) | 2017-08-18 |
| EP3013353A2 (en) | 2016-05-04 |
| JP2020055866A (ja) | 2020-04-09 |
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