BR112016017660A2 - - Google Patents

Info

Publication number
BR112016017660A2
BR112016017660A2 BR112016017660A BR112016017660A BR112016017660A2 BR 112016017660 A2 BR112016017660 A2 BR 112016017660A2 BR 112016017660 A BR112016017660 A BR 112016017660A BR 112016017660 A BR112016017660 A BR 112016017660A BR 112016017660 A2 BR112016017660 A2 BR 112016017660A2
Authority
BR
Brazil
Application number
BR112016017660A
Other languages
Portuguese (pt)
Other versions
BR112016017660B1 (pt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50184787&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112016017660(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of BR112016017660A2 publication Critical patent/BR112016017660A2/pt
Publication of BR112016017660B1 publication Critical patent/BR112016017660B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BR112016017660-0A 2014-02-27 2015-02-24 Método para a produção de uma glicoproteína recombinante BR112016017660B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14157030 2014-02-27
EP14157030.9 2014-02-27
PCT/EP2015/053804 WO2015128314A1 (en) 2014-02-27 2015-02-24 Modulation of cell growth and glycosylation in recombinant glycoprotein production

Publications (2)

Publication Number Publication Date
BR112016017660A2 true BR112016017660A2 (enExample) 2017-08-08
BR112016017660B1 BR112016017660B1 (pt) 2022-04-19

Family

ID=50184787

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016017660-0A BR112016017660B1 (pt) 2014-02-27 2015-02-24 Método para a produção de uma glicoproteína recombinante

Country Status (20)

Country Link
US (3) US20170058309A1 (enExample)
EP (1) EP3110961B1 (enExample)
JP (2) JP6831702B2 (enExample)
KR (1) KR102280638B1 (enExample)
CN (1) CN106133146B (enExample)
BR (1) BR112016017660B1 (enExample)
CA (1) CA2937611C (enExample)
DK (1) DK3110961T3 (enExample)
ES (1) ES2769003T3 (enExample)
HR (1) HRP20200100T1 (enExample)
HU (1) HUE047575T2 (enExample)
LT (1) LT3110961T (enExample)
MX (1) MX369395B (enExample)
PL (1) PL3110961T3 (enExample)
PT (1) PT3110961T (enExample)
RS (1) RS59881B1 (enExample)
RU (1) RU2712562C2 (enExample)
SG (1) SG11201606856SA (enExample)
SI (1) SI3110961T1 (enExample)
WO (1) WO2015128314A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10010029B2 (en) 2011-11-21 2018-07-03 Innovation Hammer, Llc Methods and systems for growing plants using silicate-based substrates, cultivation of enhanced photosynthetic productivity and photosafening by utilization of exogenous glycopyranosides for endogenous glycopyranosyl-protein derivatives, and formulations, processes and systems for the same
RU2712562C2 (ru) * 2014-02-27 2020-01-29 Ф.Хоффманн-Ля Рош Аг Модулирование клеточного роста и гликозилирования при производстве рекомбинантных гликопротеинов
SI3227454T1 (sl) * 2014-12-01 2020-06-30 Amgen Inc. Postopek za manipuliranje ravni vsebnosti glikana glikoproteina
JP7313150B2 (ja) 2016-04-29 2023-07-24 イノベーション・ハマー・エルエルシー グリカンコンポジット配合物で光合成生物を処理し、収穫物の品質及び量を高めるための配合物及び方法
JP7672196B2 (ja) 2017-03-14 2025-05-07 アムジエン・インコーポレーテツド 細胞培養において産生される抗体の総非フコシル化グリコフォームの調節
WO2019077628A1 (en) * 2017-10-16 2019-04-25 Council Of Scientific & Industrial Research ZINC SUPPLEMENTATION TO DECREASE GALACTOSYLATION OF RECOMBINANT GLYCOPROTEINS
WO2019178508A1 (en) * 2018-03-16 2019-09-19 Genzyme Corporation Methods for improving cell viability in a production bioreactor
KR20200135781A (ko) 2018-03-26 2020-12-03 암젠 인크 세포 배양에서 생산된 항체의 총 비푸코실화 당형태
CA3099917A1 (en) * 2018-05-24 2019-11-28 Ares Trading S.A. Method for controlling the afucosylation level of a glycoprotein composition
HU231514B1 (hu) 2018-11-07 2024-07-28 Richter Gedeon Nyrt. Sejttenyészetben előállított rekombináns glikoprotein glikozilációs mintázatának megváltoztatására szolgáló módszer
MA54248A (fr) * 2018-11-13 2021-09-22 Janssen Biotech Inc Régulation de métaux traces pendant la production d'anticorps anti-cd38
JP2020188737A (ja) * 2019-05-23 2020-11-26 東ソー株式会社 抗体依存性細胞傷害活性が向上した抗体の製造方法
CN115427443A (zh) * 2020-04-24 2022-12-02 豪夫迈·罗氏有限公司 巯基化合物及其衍生物的酶和途径调节
CN121712803A (zh) * 2023-08-16 2026-03-20 葛兰素史密斯克莱知识产权有限公司 控制抗体糖基化谱的方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4767704A (en) 1983-10-07 1988-08-30 Columbia University In The City Of New York Protein-free culture medium
IL87737A (en) 1987-09-11 1993-08-18 Genentech Inc Method for culturing polypeptide factor dependent vertebrate recombinant cells
US5705364A (en) * 1995-06-06 1998-01-06 Genentech, Inc. Mammalian cell culture process
US6030945A (en) 1996-01-09 2000-02-29 Genentech, Inc. Apo-2 ligand
WO1998008934A1 (en) 1996-08-30 1998-03-05 Life Technologies, Inc. Serum-free mammalian cell culture medium, and uses thereof
AU4314299A (en) * 1998-05-29 1999-12-13 Genentech Inc. Cell culture process for producing glycoproteins
JP2001120262A (ja) * 1999-10-26 2001-05-08 Welfide Corp 生理活性物質の産生増強方法
WO2002066603A2 (en) 2001-02-15 2002-08-29 Centocor, Inc. Chemically defined medium for cultured mammalian cells
US20050287666A1 (en) * 2004-06-29 2005-12-29 Invitrogen Corporation Cell culture medium comprising transition metals or trace elements
TWI384069B (zh) 2004-08-27 2013-02-01 Pfizer Ireland Pharmaceuticals 多胜肽之製法
KR101196103B1 (ko) * 2004-11-02 2012-11-01 아레스 트레이딩 에스.에이. 포유동물 세포용 무?혈청 세포 배양 배지
US20070231895A1 (en) 2005-11-02 2007-10-04 Lee Gene W Methods for adapting mammalian cells
US7972810B2 (en) 2005-12-08 2011-07-05 Amgen Inc. Production of glycoproteins using manganese
DK3255141T3 (da) 2006-07-13 2022-01-31 Wyeth Llc Fremstilling af antistoffer med forbedret glycosyleringsmønster
EP2395077A1 (en) 2006-11-03 2011-12-14 Wyeth LLC Glycolysis-inhibiting substances in cell culture
JP5586235B2 (ja) * 2007-03-02 2014-09-10 ワイス・エルエルシー ポリペプチドの産生のための細胞培養における銅およびグルタミン酸塩の使用
WO2011019622A1 (en) * 2009-08-14 2011-02-17 Genentech, Inc. Cell culture methods to make antibodies with enhanced adcc function
US20120309056A1 (en) * 2010-02-04 2012-12-06 Leon Arnaud Fed-batch process using concentrated cell culture medium for the efficient production of biologics in eb66 cells
RU2577972C2 (ru) 2010-04-26 2016-03-20 Новартис Аг Способ получения рекомбинантного полипептида
EP2702077A2 (en) 2011-04-27 2014-03-05 AbbVie Inc. Methods for controlling the galactosylation profile of recombinantly-expressed proteins
CN105189735B (zh) 2011-04-29 2019-04-12 拜康研究有限公司 在培养期间减少乳酸累积的方法和生产多肽的方法
EP2809773B1 (en) 2012-01-30 2020-09-02 Dr. Reddy's Laboratories Limited Process of modulating man5 and/or afucosylation content of glycoprotein composition
WO2015051293A2 (en) 2013-10-04 2015-04-09 Abbvie, Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
RU2712562C2 (ru) * 2014-02-27 2020-01-29 Ф.Хоффманн-Ля Рош Аг Модулирование клеточного роста и гликозилирования при производстве рекомбинантных гликопротеинов

Also Published As

Publication number Publication date
LT3110961T (lt) 2020-02-10
ES2769003T3 (es) 2020-06-24
US20170058309A1 (en) 2017-03-02
JP2017506515A (ja) 2017-03-09
PL3110961T3 (pl) 2020-04-30
CA2937611A1 (en) 2015-09-03
CN106133146A (zh) 2016-11-16
RU2016138176A3 (enExample) 2018-10-29
WO2015128314A1 (en) 2015-09-03
RU2016138176A (ru) 2018-03-29
BR112016017660B1 (pt) 2022-04-19
HUE047575T2 (hu) 2020-04-28
DK3110961T3 (da) 2020-02-03
MX2016010236A (es) 2016-10-13
KR102280638B1 (ko) 2021-07-22
CA2937611C (en) 2023-01-03
EP3110961B1 (en) 2019-11-27
MX369395B (es) 2019-11-07
EP3110961A1 (en) 2017-01-04
KR20160125514A (ko) 2016-10-31
JP6831702B2 (ja) 2021-02-17
SG11201606856SA (en) 2016-09-29
SI3110961T1 (sl) 2020-03-31
JP2020054351A (ja) 2020-04-09
JP6934507B2 (ja) 2021-09-15
RS59881B1 (sr) 2020-03-31
US20210222220A1 (en) 2021-07-22
PT3110961T (pt) 2020-01-29
US20240327890A1 (en) 2024-10-03
RU2712562C2 (ru) 2020-01-29
CN106133146B (zh) 2021-05-04
HRP20200100T1 (hr) 2020-04-03

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B09X Republication of the decision to grant [chapter 9.1.3 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/02/2015, OBSERVADAS AS CONDICOES LEGAIS.