BR112016003533A2 - crescimento controlado de micro-organismos - Google Patents

crescimento controlado de micro-organismos

Info

Publication number
BR112016003533A2
BR112016003533A2 BR112016003533A BR112016003533A BR112016003533A2 BR 112016003533 A2 BR112016003533 A2 BR 112016003533A2 BR 112016003533 A BR112016003533 A BR 112016003533A BR 112016003533 A BR112016003533 A BR 112016003533A BR 112016003533 A2 BR112016003533 A2 BR 112016003533A2
Authority
BR
Brazil
Prior art keywords
growth
microbial cells
microorganisms
microbial
controlled growth
Prior art date
Application number
BR112016003533A
Other languages
English (en)
Other versions
BR112016003533B1 (pt
Inventor
Gabant Philippe
Original Assignee
Syngulon Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngulon Sa filed Critical Syngulon Sa
Publication of BR112016003533A2 publication Critical patent/BR112016003533A2/pt
Publication of BR112016003533B1 publication Critical patent/BR112016003533B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

resumo "crescimento controlado de micro-organismos" pode ser útil regular o crescimento de células microbianas. algumas modalidades citadas aqui fornecem células microbianas geneticamente modificadas que podem produzir bacteriocinas para controlar o crescimento das células microbianas. em algumas modalidades, as células microbianas estão contidas dentro de um ambiente desejado. em algumas modalidades, as células microbianas contaminantes são neutralizadas. em algumas modalidades, um primeiro tipo de célula microbiana regula o crescimento de um segundo tipo de célula microbiana, de modo a manter uma relação desejada dos dois tipos de células.
BR112016003533-0A 2013-08-19 2014-08-14 Célula microbiana geneticamente modificada e método para controlar o crescimento de uma segunda célula microbiana em um meio de cultura BR112016003533B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361867510P 2013-08-19 2013-08-19
US61/867.510 2013-08-19
PCT/EP2014/067418 WO2015024855A1 (en) 2013-08-19 2014-08-14 Controlled growth of microorganisms

Publications (2)

Publication Number Publication Date
BR112016003533A2 true BR112016003533A2 (pt) 2017-12-05
BR112016003533B1 BR112016003533B1 (pt) 2021-11-03

Family

ID=51483393

Family Applications (2)

Application Number Title Priority Date Filing Date
BR112016003533-0A BR112016003533B1 (pt) 2013-08-19 2014-08-14 Célula microbiana geneticamente modificada e método para controlar o crescimento de uma segunda célula microbiana em um meio de cultura
BR122021015417-1A BR122021015417B1 (pt) 2013-08-19 2014-08-14 Célula microbiana geneticamente engenheirada que compreende um ácido nucleico que codifica uma bacteriocina

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR122021015417-1A BR122021015417B1 (pt) 2013-08-19 2014-08-14 Célula microbiana geneticamente engenheirada que compreende um ácido nucleico que codifica uma bacteriocina

Country Status (7)

Country Link
US (4) US9333227B2 (pt)
EP (2) EP3984366A1 (pt)
CN (3) CN105658070B (pt)
BR (2) BR112016003533B1 (pt)
DK (1) DK3035802T3 (pt)
ES (1) ES2893454T3 (pt)
WO (1) WO2015024855A1 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105658070B (zh) 2013-08-19 2019-10-18 辛格隆股份公司 微生物的受控生长
AU2016256882B2 (en) 2015-05-05 2022-06-02 The Regents Of The University Of California Antimicrobial therapy
EP3097783B1 (en) 2015-05-26 2019-11-13 Nomad Bioscience GmbH Colicin m for the control of ehec
WO2016210373A2 (en) 2015-06-24 2016-12-29 Synlogic, Inc. Recombinant bacteria engineered for biosafety, pharmaceutical compositions, and methods of use thereof
WO2017175239A1 (en) * 2016-04-05 2017-10-12 Council Of Scientific & Industrial Research A multifunctional recombinant nucleotide dependent glycosyltransferase protein and its method of glycosylation thereof
EP3491142A1 (en) * 2016-07-13 2019-06-05 Wisconsin Alumni Research Foundation Use of bacteriocin-producing ethanologens in biofuel production
US20180042990A1 (en) * 2016-08-15 2018-02-15 National Chung Hsing University Method for improving an intestinal microflora and promoting growth of animals by using colicin or microorganism capable of expressing the same
EP3378485A1 (en) * 2017-03-24 2018-09-26 Nomad Bioscience GmbH Bacteriocins for control of salmonella enterica
WO2019046577A1 (en) * 2017-08-31 2019-03-07 Syngulon Sa METHODS AND COMPOSITIONS FOR THE PRODUCTION OF BACTERIOCIN AND ANTIMICROBIAL PEPTIDES
US11932672B2 (en) 2017-12-19 2024-03-19 Syngulon S.A. Fermentation process
WO2020047203A2 (en) * 2018-08-30 2020-03-05 Osel, Inc. Bacteriocins to improve vaginal colonization of hydrogen peroxide producing lactobacillus for female reproductive health
CN109161508A (zh) * 2018-09-30 2019-01-08 上海景峰制药有限公司 一种微生物培养基及其制备方法与应用
EP3883949A1 (en) 2018-11-22 2021-09-29 Syngulon S.A. Peptides for inducing bacteriocin synthesis and methods to identify and/or select and/or optimize the same
WO2020240042A1 (en) * 2019-05-31 2020-12-03 Chr. Hansen A/S Composition comprising lactococcus, methods and products thereof
CN111440247A (zh) * 2020-04-20 2020-07-24 广西南宁三思百乐生物科技有限公司 抑杀沙门氏菌、产气荚膜梭菌的抗菌肽融合蛋白及其应用
EP4165063A1 (en) 2020-06-15 2023-04-19 Melio Peptide Systems Inc. Microorganisms and methods for reducing bacterial contamination
CN116669557A (zh) * 2020-11-10 2023-08-29 辛格隆股份公司 微生物群落中微生物的控制
WO2022104321A1 (en) * 2020-11-10 2022-05-19 Syngulon Sa. Modulating antimicrobial peptide half-life
CN112521456B (zh) * 2020-12-18 2021-09-10 福建傲农生物科技集团股份有限公司 一种抗菌肽及其制备方法与应用
CN112574929B (zh) * 2021-01-11 2022-06-07 吉林大学 一株吉林类芽孢杆菌ypg26及其医用用途
US20240197820A1 (en) 2021-06-02 2024-06-20 Syngulon S.A. Bacteriocin for new application
EP4346870A1 (en) * 2021-06-02 2024-04-10 Syngulon S.A. Bacteriocin for new application
WO2023041435A1 (en) 2021-09-14 2023-03-23 Syngulon S.A. Bacteriocin for applications against mycobacterium
WO2023215798A1 (en) * 2022-05-04 2023-11-09 Locus Biosciences, Inc. Phage compositions for escherichia comprising crispr-cas systems and methods of use thereof
WO2023235682A1 (en) 2022-05-31 2023-12-07 Syngulon Sa Bacteriocin polypeptides, nucleic acids encoding same, and methods of use thereof
WO2024027860A1 (en) * 2022-08-05 2024-02-08 Česká zemědělská univerzita v Praze A bacteriocin composition for coding linocin-m18-like protein with antimicrobial activity and its usage

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US618040A (en) 1899-01-17 Du nib-waiter
EP0273040B1 (en) 1986-03-26 1994-06-22 GX BioSystems A/S Biological containment
US5464764A (en) 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
US5300431A (en) 1991-02-26 1994-04-05 E. I. Du Pont De Nemours And Company Positive selection vector for the bacteriophage P1 cloning system
US7176029B2 (en) 1992-07-31 2007-02-13 Universite Libre De Bruxelles Cloning and/or sequencing vector
BE1006085A3 (fr) * 1992-07-31 1994-05-10 Univ Bruxelles Vecteur de clonage.
US5549895A (en) 1993-05-17 1996-08-27 Iowa State University Research Foundation, Inc. Method and colicin composition for inhibiting Escherichia coli 0157:H7 in food products
JP2590761B2 (ja) 1994-11-22 1997-03-12 日本電気株式会社 Ｔａｂ式半導体装置およびｔａｂ式半導体装置を回路基板に接続する方法
US6143557A (en) 1995-06-07 2000-11-07 Life Technologies, Inc. Recombination cloning using engineered recombination sites
CA2226463A1 (en) 1995-06-07 1996-12-19 Life Technologies, Inc. Recombinational cloning using engineered recombination sites
US5677175A (en) 1995-10-13 1997-10-14 Purdue Research Foundation Plant pathogen induced proteins
US5922583A (en) 1995-10-17 1999-07-13 Biostar Inc. Methods for production of recombinant plasmids
AU8392698A (en) * 1997-07-09 1999-02-08 Governors Of The University Of Alberta, The Novel bacteriocins, transport and vector system and method of use thereof
JP4303418B2 (ja) 1997-10-24 2009-07-29 ライフ テクノロジーズ コーポレーション 組換え部位を有する核酸を使用する組換えクローニング
FR2770536B1 (fr) * 1997-11-06 2001-09-21 Texel Nouveau plasmide non rcr apte a etre transfere dans des bact eries lactiques; utilisation comme outil de clonage et d'expression
CA2327387C (en) 1998-05-07 2012-07-03 Gx Biosystems A/S Cytotoxin-based biological containment
US6271359B1 (en) 1999-04-14 2001-08-07 Musc Foundation For Research Development Tissue-specific and pathogen-specific toxic agents and ribozymes
CN1399684A (zh) 1999-10-25 2003-02-26 茵维特罗根公司 使用转座和重组以操作和测序核酸分子的方法
ATE391789T1 (de) 1999-12-10 2008-04-15 Invitrogen Corp Verwendung einer vielzahl von rekombinationsstellen mit einzigartiger spezifität beim rekombinatorischen klonen
EP1111061A1 (en) 1999-12-20 2001-06-27 Universite Libre De Bruxelles Double selection vector
DE10038573A1 (de) 2000-08-03 2002-02-21 Mpb Cologne Gmbh Molecular Pla Verfahren zur Selektion auf Wirtszellen mit eliminierten DNA-Sequenzen
CA2435956C (en) 2001-02-23 2012-07-10 Universite Libre De Bruxelles Method for the selection of recombinant clones comprising a sequence encoding an antidote protein to toxic molecule
US20050260585A1 (en) 2002-03-19 2005-11-24 Cedric Szpirer Poison/antidote genetic systems for the selection of genetically modified eucaryote cells or organisms
US9309518B2 (en) 2002-09-03 2016-04-12 Universite Libre De Bruxelles Reversible, parallel and multitask cloning method and kit
CA2496514C (en) 2002-09-03 2012-11-06 Universite Libre De Bruxelles Reversible, parallel and multitask cloning method and kit
WO2010060057A1 (en) * 2008-11-22 2010-05-27 Southern Illinois University Edwarsville Bacteriocin based methods to control lactic acid bacterial growth
US20100330041A1 (en) 2009-05-27 2010-12-30 Bayrock Dennis P Viral-based antimicrobial agent use in ethanol production
US8476048B2 (en) 2010-12-17 2013-07-02 E I Du Pont De Nemours And Company Xylose utilizing zymomonas mobilis with improved ethanol production in biomass hydrolysate medium
EP2543255B2 (en) * 2011-07-04 2022-12-28 DSM IP Assets B.V. Anti-listerial mixed culture and method for producing cheese
US8697426B2 (en) 2012-06-15 2014-04-15 E I Du Pont De Nemours And Company Contaminant control in Zymomonas fermentation using virginiamycin
US20140148379A1 (en) 2012-11-28 2014-05-29 Mei Liu Control of Unwanted Bacteria in Fermentation Systems with Bacteriocin
US8846357B2 (en) 2012-12-20 2014-09-30 E I Du Pont De Nemours And Company Stabilized chlorine dioxide for contamination control in Zymomonas fermentation
CN105658070B (zh) 2013-08-19 2019-10-18 辛格隆股份公司 微生物的受控生长
US11932672B2 (en) 2017-12-19 2024-03-19 Syngulon S.A. Fermentation process

Also Published As

Publication number Publication date
US10188114B2 (en) 2019-01-29
EP3035802B1 (en) 2021-07-07
US20190191709A1 (en) 2019-06-27
US20230193191A1 (en) 2023-06-22
CN110564663B (zh) 2023-03-10
US9333227B2 (en) 2016-05-10
EP3984366A1 (en) 2022-04-20
BR112016003533B1 (pt) 2021-11-03
US20160213005A1 (en) 2016-07-28
CN116218753A (zh) 2023-06-06
WO2015024855A1 (en) 2015-02-26
CN105658070A (zh) 2016-06-08
ES2893454T3 (es) 2022-02-09
DK3035802T3 (da) 2021-10-11
BR122021015417B1 (pt) 2022-11-08
EP3035802A1 (en) 2016-06-29
US11427800B2 (en) 2022-08-30
US20150050253A1 (en) 2015-02-19
CN105658070B (zh) 2019-10-18
CN110564663A (zh) 2019-12-13

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
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