BR112014017188A8 - células hospedeiras com endossimbiontes artificiais - Google Patents
células hospedeiras com endossimbiontes artificiaisInfo
- Publication number
- BR112014017188A8 BR112014017188A8 BR112014017188A BR112014017188A BR112014017188A8 BR 112014017188 A8 BR112014017188 A8 BR 112014017188A8 BR 112014017188 A BR112014017188 A BR 112014017188A BR 112014017188 A BR112014017188 A BR 112014017188A BR 112014017188 A8 BR112014017188 A8 BR 112014017188A8
- Authority
- BR
- Brazil
- Prior art keywords
- cells
- eukaryotic
- host cells
- artificial endosymbionts
- eukaryotic cells
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
- C12N5/166—Animal cells resulting from interspecies fusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
- C12N15/03—Bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y406/00—Phosphorus-oxygen lyases (4.6)
- C12Y406/01—Phosphorus-oxygen lyases (4.6.1)
- C12Y406/01001—Aodenylate cyclase (4.6.1.1)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
resumo células hospedeiras com endossimbiontes artificiais a presente invenção é dirigida geralmente a células eucarióticas compreendendo organismos unicelulares, que são introduzidas na célula eucariótica, por meio de intervenção humana, e que a transferência para células filhas de células eucarióticas por meio de, pelo menos, cinco divisões celulares, e métodos de introdução de tais única cancelou organismos em células eucarióticas. a invenção fornece organismos unicelulares que apresentam um fenótipo de células eucarióticas que é mantida em células-filhas. a invenção também fornece células eucarióticas contendo bactérias magnetotácticos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/374,799 US8956873B2 (en) | 2012-01-13 | 2012-01-13 | Host cells with artificial endosymbionts |
PCT/US2013/021414 WO2013106814A1 (en) | 2012-01-13 | 2013-01-14 | Host cells with artificial endosymbionts |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112014017188A2 BR112014017188A2 (pt) | 2017-06-13 |
BR112014017188A8 true BR112014017188A8 (pt) | 2017-07-04 |
Family
ID=48780236
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014017188A BR112014017188A8 (pt) | 2012-01-13 | 2013-01-14 | células hospedeiras com endossimbiontes artificiais |
Country Status (13)
Country | Link |
---|---|
US (6) | US8956873B2 (pt) |
EP (2) | EP2802334B1 (pt) |
JP (2) | JP6328057B2 (pt) |
KR (1) | KR20140116195A (pt) |
CN (1) | CN104159593A (pt) |
AU (1) | AU2013207734B2 (pt) |
BR (1) | BR112014017188A8 (pt) |
CA (1) | CA2863331A1 (pt) |
HK (1) | HK1200014A1 (pt) |
IL (1) | IL233498A0 (pt) |
NZ (1) | NZ627091A (pt) |
SG (1) | SG11201404013SA (pt) |
WO (1) | WO2013106814A1 (pt) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9023612B2 (en) | 2012-01-13 | 2015-05-05 | Bell Biosystems, Inc. | Eukaryotic cells with artificial endosymbionts for multimodal detection |
US8956873B2 (en) | 2012-01-13 | 2015-02-17 | Bell Biosystems, Inc. | Host cells with artificial endosymbionts |
US8828681B2 (en) | 2012-01-13 | 2014-09-09 | Bell Biosystems, Inc. | Host cells with artificial endosymbionts |
US10076579B2 (en) | 2012-01-13 | 2018-09-18 | Bell Biosystems, Inc. | Host cells with artificial endosymbionts |
WO2014145785A1 (en) | 2013-03-15 | 2014-09-18 | Bell Biosystems, Llc | Host cells with artificial endosymbionts |
EP3007731B1 (en) * | 2013-06-10 | 2018-03-07 | Universität Bayreuth | Production of magnetic nanoparticles in recombinant host cells |
SG11201601488VA (en) * | 2013-09-03 | 2016-03-30 | Bell Biosystems Inc | Host cell modification with artificial endosymbionts |
US9580758B2 (en) | 2013-11-12 | 2017-02-28 | Luc Montagnier | System and method for the detection and treatment of infection by a microbial agent associated with HIV infection |
WO2015123409A1 (en) * | 2014-02-13 | 2015-08-20 | Bell Biosystems, Inc. | Systems for making host cells with artificial endosymbionts |
JP2017522022A (ja) * | 2014-07-15 | 2017-08-10 | ベル・バイオシステムズ,インコーポレーテッド | マルチモーダル検出のための人工内部共生体を含む真核細胞 |
WO2016054298A1 (en) * | 2014-10-01 | 2016-04-07 | Bell Biosystems, Inc. | Magnetogenetics |
CN106486514B (zh) | 2015-08-31 | 2023-12-01 | 昆山国显光电有限公司 | 像素结构以及oled显示面板 |
CN113444739A (zh) * | 2021-06-20 | 2021-09-28 | 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) | 一种诱导表达绿色荧光蛋白广宿主质粒的构建及其在荧光示踪中的应用 |
CN114634877B (zh) * | 2022-04-14 | 2023-11-24 | 浙江大学 | 一种生物光合细胞器的合成方法及其产品和应用 |
Family Cites Families (36)
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US4385119A (en) | 1980-03-27 | 1983-05-24 | Biomagnetech Corp. | Magnetic bacteria and products derived therefrom |
US4677067A (en) | 1984-06-22 | 1987-06-30 | Bio-Magnetech Corporation | Magnetotactic bacteria in clinical assay, immunoassay, and cell separation procedures and the like |
JPS62275679A (ja) * | 1986-05-23 | 1987-11-30 | Tdk Corp | 磁気微粒子含有細胞の製法 |
US5843643A (en) | 1992-02-21 | 1998-12-01 | Ratner; Paul L. | Site-specific transfection of eukaryotic cells using polypeptide-linked recombinant nucleic acid |
US6436694B1 (en) | 1998-01-09 | 2002-08-20 | Cubist Pharmaceuticals, Inc. | Regulable gene expression in gram-positive bacteria |
US6004815A (en) | 1998-08-13 | 1999-12-21 | The Regents Of The University Of California | Bacteria expressing nonsecreted cytolysin as intracellular microbial delivery vehicles to eukaryotic cells |
US8406498B2 (en) | 1999-01-25 | 2013-03-26 | Amnis Corporation | Blood and cell analysis using an imaging flow cytometer |
US20020012698A1 (en) | 1999-09-01 | 2002-01-31 | Edmund Bauerlein | Magnetosomes, method for making and using |
EP1281767A3 (en) | 2001-07-31 | 2003-05-28 | Aladar A. Szalay | Light emitting microorganisms and cells for diagnosis and therapy of tumors |
GB0121126D0 (en) | 2001-08-31 | 2001-10-24 | Univ Nottingham | Systemic non-nodular endosymbiotic nitrogen fixation in plants |
AU2004289953B2 (en) | 2003-06-18 | 2008-09-25 | Genelux Corporation | Modified recombinant vaccina viruses and other microorganisms, uses thereof |
US7390646B2 (en) | 2003-09-17 | 2008-06-24 | The Regents Of The University Of California | Bacterial vectors and methods of use thereof |
GB0329310D0 (en) | 2003-12-18 | 2004-01-21 | Univ Keele | Method |
EP1655370A1 (en) | 2004-11-05 | 2006-05-10 | Gesellschaft für Biotechnologische Forschung | Bacterial vector |
WO2006119102A1 (en) | 2005-04-29 | 2006-11-09 | Emory University | Methods and compositions for the production and use of magnetosomes |
JP5119398B2 (ja) * | 2005-06-03 | 2013-01-16 | 国立大学法人東京農工大学 | 磁性粒子保持担体、およびその調製方法 |
EP1919507A2 (en) | 2005-08-04 | 2008-05-14 | Thomas William Rademacher | Nanoparticles comprising antibacterial ligands |
WO2007112107A2 (en) | 2006-03-24 | 2007-10-04 | Gencia Corporation | Synthetic lipid rafts and methods of use |
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US20100135912A1 (en) | 2008-12-02 | 2010-06-03 | Gambhir Sanjiv S | Magnetotactic bacteria mri positive contrast enhancement agent and methods of use |
US9340775B2 (en) | 2009-03-25 | 2016-05-17 | The Salk Institute For Biological Studies | Induced pluripotent stem cell produced by transfecting a human neural stem cell with an episomal vector encoding the Oct4 and Nanog proteins |
GB0905331D0 (en) | 2009-03-27 | 2009-05-13 | Avecia Biolog Ltd | Expression process |
FR2948125B1 (fr) | 2009-07-17 | 2011-08-26 | Zoran Dermanovic | Procedes d'etablissement de symbioses |
US9359623B2 (en) | 2009-07-24 | 2016-06-07 | The Regents Of The University Of California | Methods and compositions for the production of fatty acids in photosynthetic prokaryotic microorganisms |
JP6202358B2 (ja) | 2009-11-18 | 2017-09-27 | ナノバクテリー | 走磁性細菌から抽出され交流磁場に供されたマグネトソームの様々な鎖により生成される熱の放出により誘導される、癌または腫瘍の治療 |
US8617888B2 (en) | 2010-07-23 | 2013-12-31 | University Of Florida Research Foundation, Inc. | Bacterial mediated delivery of nuclear protein into pluripotent and differentiated cells |
US9023612B2 (en) * | 2012-01-13 | 2015-05-05 | Bell Biosystems, Inc. | Eukaryotic cells with artificial endosymbionts for multimodal detection |
US8956873B2 (en) * | 2012-01-13 | 2015-02-17 | Bell Biosystems, Inc. | Host cells with artificial endosymbionts |
US8828681B2 (en) | 2012-01-13 | 2014-09-09 | Bell Biosystems, Inc. | Host cells with artificial endosymbionts |
US9387264B2 (en) | 2012-04-05 | 2016-07-12 | Yeda Research And Development Co. Ltd. | Reporter genes for magnetic resonance imaging and methods of use thereof |
CA2883714A1 (en) | 2012-09-07 | 2014-03-13 | Genentech, Inc. | Methods and compositions for producing induced hepatocytes |
WO2014145785A1 (en) * | 2013-03-15 | 2014-09-18 | Bell Biosystems, Llc | Host cells with artificial endosymbionts |
SG11201601488VA (en) | 2013-09-03 | 2016-03-30 | Bell Biosystems Inc | Host cell modification with artificial endosymbionts |
-
2012
- 2012-01-13 US US13/374,799 patent/US8956873B2/en not_active Expired - Fee Related
-
2013
- 2013-01-14 BR BR112014017188A patent/BR112014017188A8/pt not_active IP Right Cessation
- 2013-01-14 WO PCT/US2013/021414 patent/WO2013106814A1/en active Application Filing
- 2013-01-14 SG SG11201404013SA patent/SG11201404013SA/en unknown
- 2013-01-14 CA CA2863331A patent/CA2863331A1/en not_active Abandoned
- 2013-01-14 EP EP13736256.2A patent/EP2802334B1/en not_active Not-in-force
- 2013-01-14 EP EP17001355.1A patent/EP3263696A1/en not_active Withdrawn
- 2013-01-14 CN CN201380013027.8A patent/CN104159593A/zh active Pending
- 2013-01-14 JP JP2014552366A patent/JP6328057B2/ja not_active Expired - Fee Related
- 2013-01-14 NZ NZ627091A patent/NZ627091A/en not_active IP Right Cessation
- 2013-01-14 AU AU2013207734A patent/AU2013207734B2/en not_active Ceased
- 2013-01-14 KR KR1020147022388A patent/KR20140116195A/ko not_active Application Discontinuation
-
2014
- 2014-07-03 IL IL233498A patent/IL233498A0/en unknown
- 2014-12-24 US US14/582,823 patent/US9085764B2/en not_active Expired - Fee Related
-
2015
- 2015-01-14 HK HK15100415.0A patent/HK1200014A1/xx unknown
- 2015-06-08 US US14/732,911 patent/US9458432B2/en not_active Expired - Fee Related
-
2016
- 2016-09-12 US US15/263,257 patent/US9657275B2/en not_active Expired - Fee Related
-
2017
- 2017-05-13 US US15/594,595 patent/US10023843B2/en not_active Expired - Fee Related
-
2018
- 2018-03-05 JP JP2018038279A patent/JP2018108107A/ja active Pending
- 2018-07-12 US US16/033,679 patent/US10280403B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
AU2013207734A1 (en) | 2014-07-24 |
US20160376561A1 (en) | 2016-12-29 |
IL233498A0 (en) | 2014-08-31 |
US20150152391A1 (en) | 2015-06-04 |
US20130183758A1 (en) | 2013-07-18 |
SG11201404013SA (en) | 2014-10-30 |
JP2015504680A (ja) | 2015-02-16 |
US20150267175A1 (en) | 2015-09-24 |
JP2018108107A (ja) | 2018-07-12 |
KR20140116195A (ko) | 2014-10-01 |
BR112014017188A2 (pt) | 2017-06-13 |
NZ627091A (en) | 2017-01-27 |
CA2863331A1 (en) | 2013-07-18 |
EP2802334A4 (en) | 2015-08-19 |
US10280403B2 (en) | 2019-05-07 |
EP2802334B1 (en) | 2018-03-07 |
CN104159593A (zh) | 2014-11-19 |
US20180327721A1 (en) | 2018-11-15 |
EP2802334A1 (en) | 2014-11-19 |
US8956873B2 (en) | 2015-02-17 |
HK1200014A1 (en) | 2015-07-31 |
US9085764B2 (en) | 2015-07-21 |
WO2013106814A1 (en) | 2013-07-18 |
US20170247663A1 (en) | 2017-08-31 |
AU2013207734B2 (en) | 2017-09-07 |
US9657275B2 (en) | 2017-05-23 |
EP3263696A1 (en) | 2018-01-03 |
JP6328057B2 (ja) | 2018-05-23 |
US9458432B2 (en) | 2016-10-04 |
US10023843B2 (en) | 2018-07-17 |
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
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