BR112014017188A2 - células hospedeiras com endossimbiontes artificiais - Google Patents

células hospedeiras com endossimbiontes artificiais

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Publication number
BR112014017188A2
BR112014017188A2 BR112014017188A BR112014017188A BR112014017188A2 BR 112014017188 A2 BR112014017188 A2 BR 112014017188A2 BR 112014017188 A BR112014017188 A BR 112014017188A BR 112014017188 A BR112014017188 A BR 112014017188A BR 112014017188 A2 BR112014017188 A2 BR 112014017188A2
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BR
Brazil
Prior art keywords
cells
eukaryotic
host cells
artificial endosymbionts
eukaryotic cells
Prior art date
Application number
BR112014017188A
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English (en)
Other versions
BR112014017188A8 (pt
Inventor
Bazarov Alexey
B Bell Caleb Iii
Original Assignee
Bell Biosystems Inc
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Filing date
Publication date
Application filed by Bell Biosystems Inc filed Critical Bell Biosystems Inc
Publication of BR112014017188A2 publication Critical patent/BR112014017188A2/pt
Publication of BR112014017188A8 publication Critical patent/BR112014017188A8/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/166—Animal cells resulting from interspecies fusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • C12N15/03—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y406/00—Phosphorus-oxygen lyases (4.6)
    • C12Y406/01—Phosphorus-oxygen lyases (4.6.1)
    • C12Y406/01001—Aodenylate cyclase (4.6.1.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

resumo células hospedeiras com endossimbiontes artificiais a presente invenção é dirigida geralmente a células eucarióticas compreendendo organismos unicelulares, que são introduzidas na célula eucariótica, por meio de intervenção humana, e que a transferência para células filhas de células eucarióticas por meio de, pelo menos, cinco divisões celulares, e métodos de introdução de tais única cancelou organismos em células eucarióticas. a invenção fornece organismos unicelulares que apresentam um fenótipo de células eucarióticas que é mantida em células-filhas. a invenção também fornece células eucarióticas contendo bactérias magnetotácticos.
BR112014017188A 2012-01-13 2013-01-14 células hospedeiras com endossimbiontes artificiais BR112014017188A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/374,799 US8956873B2 (en) 2012-01-13 2012-01-13 Host cells with artificial endosymbionts
PCT/US2013/021414 WO2013106814A1 (en) 2012-01-13 2013-01-14 Host cells with artificial endosymbionts

Publications (2)

Publication Number Publication Date
BR112014017188A2 true BR112014017188A2 (pt) 2017-06-13
BR112014017188A8 BR112014017188A8 (pt) 2017-07-04

Family

ID=48780236

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014017188A BR112014017188A8 (pt) 2012-01-13 2013-01-14 células hospedeiras com endossimbiontes artificiais

Country Status (13)

Country Link
US (6) US8956873B2 (pt)
EP (2) EP2802334B1 (pt)
JP (2) JP6328057B2 (pt)
KR (1) KR20140116195A (pt)
CN (1) CN104159593A (pt)
AU (1) AU2013207734B2 (pt)
BR (1) BR112014017188A8 (pt)
CA (1) CA2863331A1 (pt)
HK (1) HK1200014A1 (pt)
IL (1) IL233498A0 (pt)
NZ (1) NZ627091A (pt)
SG (1) SG11201404013SA (pt)
WO (1) WO2013106814A1 (pt)

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US9023612B2 (en) 2012-01-13 2015-05-05 Bell Biosystems, Inc. Eukaryotic cells with artificial endosymbionts for multimodal detection
US8956873B2 (en) 2012-01-13 2015-02-17 Bell Biosystems, Inc. Host cells with artificial endosymbionts
US8828681B2 (en) 2012-01-13 2014-09-09 Bell Biosystems, Inc. Host cells with artificial endosymbionts
US10076579B2 (en) 2012-01-13 2018-09-18 Bell Biosystems, Inc. Host cells with artificial endosymbionts
WO2014145785A1 (en) 2013-03-15 2014-09-18 Bell Biosystems, Llc Host cells with artificial endosymbionts
EP3007731B1 (en) * 2013-06-10 2018-03-07 Universität Bayreuth Production of magnetic nanoparticles in recombinant host cells
SG11201601488VA (en) * 2013-09-03 2016-03-30 Bell Biosystems Inc Host cell modification with artificial endosymbionts
US9580758B2 (en) 2013-11-12 2017-02-28 Luc Montagnier System and method for the detection and treatment of infection by a microbial agent associated with HIV infection
WO2015123409A1 (en) * 2014-02-13 2015-08-20 Bell Biosystems, Inc. Systems for making host cells with artificial endosymbionts
JP2017522022A (ja) * 2014-07-15 2017-08-10 ベル・バイオシステムズ，インコーポレーテッド マルチモーダル検出のための人工内部共生体を含む真核細胞
WO2016054298A1 (en) * 2014-10-01 2016-04-07 Bell Biosystems, Inc. Magnetogenetics
CN106486514B (zh) 2015-08-31 2023-12-01 昆山国显光电有限公司 像素结构以及oled显示面板
CN113444739A (zh) * 2021-06-20 2021-09-28 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) 一种诱导表达绿色荧光蛋白广宿主质粒的构建及其在荧光示踪中的应用
CN114634877B (zh) * 2022-04-14 2023-11-24 浙江大学 一种生物光合细胞器的合成方法及其产品和应用

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JPS62275679A (ja) * 1986-05-23 1987-11-30 Tdk Corp 磁気微粒子含有細胞の製法
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Also Published As

Publication number Publication date
AU2013207734A1 (en) 2014-07-24
US20160376561A1 (en) 2016-12-29
IL233498A0 (en) 2014-08-31
US20150152391A1 (en) 2015-06-04
US20130183758A1 (en) 2013-07-18
SG11201404013SA (en) 2014-10-30
JP2015504680A (ja) 2015-02-16
US20150267175A1 (en) 2015-09-24
JP2018108107A (ja) 2018-07-12
KR20140116195A (ko) 2014-10-01
NZ627091A (en) 2017-01-27
CA2863331A1 (en) 2013-07-18
EP2802334A4 (en) 2015-08-19
US10280403B2 (en) 2019-05-07
EP2802334B1 (en) 2018-03-07
CN104159593A (zh) 2014-11-19
US20180327721A1 (en) 2018-11-15
EP2802334A1 (en) 2014-11-19
US8956873B2 (en) 2015-02-17
HK1200014A1 (en) 2015-07-31
US9085764B2 (en) 2015-07-21
WO2013106814A1 (en) 2013-07-18
US20170247663A1 (en) 2017-08-31
AU2013207734B2 (en) 2017-09-07
US9657275B2 (en) 2017-05-23
EP3263696A1 (en) 2018-01-03
BR112014017188A8 (pt) 2017-07-04
JP6328057B2 (ja) 2018-05-23
US9458432B2 (en) 2016-10-04
US10023843B2 (en) 2018-07-17

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