BR112015031320A2 - sistema para produção de aditivo de estruturas tridimensionais e método para a mesma - Google Patents

sistema para produção de aditivo de estruturas tridimensionais e método para a mesma

Info

Publication number
BR112015031320A2
BR112015031320A2 BR112015031320A BR112015031320A BR112015031320A2 BR 112015031320 A2 BR112015031320 A2 BR 112015031320A2 BR 112015031320 A BR112015031320 A BR 112015031320A BR 112015031320 A BR112015031320 A BR 112015031320A BR 112015031320 A2 BR112015031320 A2 BR 112015031320A2
Authority
BR
Brazil
Prior art keywords
materials
printhead
dispensing
receiving
dimensional structures
Prior art date
Application number
BR112015031320A
Other languages
English (en)
Other versions
BR112015031320B1 (pt
Inventor
Amjad Mohammed Bsoul Anas
Walus Konrad
Travis Beyer Simon
Mohamed Tamer
Original Assignee
Aspect Biosystems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52021536&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112015031320(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aspect Biosystems Ltd filed Critical Aspect Biosystems Ltd
Publication of BR112015031320A2 publication Critical patent/BR112015031320A2/pt
Publication of BR112015031320B1 publication Critical patent/BR112015031320B1/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10—Processes of additive manufacturing
    • B29C64/106—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01—Ink jet
    • B41J2/015—Ink jet characterised by the jet generation process
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10—Processes of additive manufacturing
    • B29C64/106—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material
    • B29C64/112—Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using individual droplets, e.g. from jetting heads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/20—Apparatus for additive manufacturing; Details thereof or accessories therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/20—Apparatus for additive manufacturing; Details thereof or accessories therefor
    • B29C64/205—Means for applying layers
    • B29C64/209—Heads; Nozzles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/30—Auxiliary operations or equipment
    • B29C64/386—Data acquisition or data processing for additive manufacturing
    • B29C64/393—Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C70/00—Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00—Processes of additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y30/00—Apparatus for additive manufacturing; Details thereof or accessories therefor
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0058—Liquid or visquous
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/0058—Liquid or visquous
    • B29K2105/0061—Gel or sol
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y50/00—Data acquisition or data processing for additive manufacturing
    • B33Y50/02—Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/00—3D culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers

Abstract

resumo “sistema para produção de aditivo de estruturas tridimensionais e método para a mesma” trata-se de um sistema e método para produção de aditivo de estruturas tri-dimensionais, que inclui estruturas celulares tridimensionais. o sistema compreen-de pelo menos um cabeçote de impressão para receber e distribuir materiais, os ma-teriais que compreendem um fluido de revestimento e um hidrogel, o cabeçote de impressão que compreende um orifício para distribuir os materiais, canais microfluí-dicos para receber e direcionar os materiais, os comutadores fluídicos que corres-pondem a um dentre os canais microfluídicos no cabeçote de impressão e configu-rados para permitir ou não permitir o fluxo de fluido nos canais microfluídicos; uma superfície receptora para receber uma primeira camada dos materiais distribuídos a partir do orifício; uma unidade de posicionamento para posicionar o orifício do cabe-çote de impressão no espaço tridimensional; e um meio de distribuição para distribu-ir os materiais a partir do orifício do cabeçote de impressão.
BR112015031320-5A 2013-06-13 2014-06-13 Sistema para manufatura aditiva de estruturas tridimensionais e método de impressão de uma estrutura tridimensional BR112015031320B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361834420P 2013-06-13 2013-06-13
US61/834.420 2013-06-13
PCT/CA2014/050556 WO2014197999A1 (en) 2013-06-13 2014-06-13 System for additive manufacturing of three-dimensional structures and method for same

Publications (2)

Publication Number Publication Date
BR112015031320A2 true BR112015031320A2 (pt) 2017-07-25
BR112015031320B1 BR112015031320B1 (pt) 2022-01-18

Family

ID=52021536

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015031320-5A BR112015031320B1 (pt) 2013-06-13 2014-06-13 Sistema para manufatura aditiva de estruturas tridimensionais e método de impressão de uma estrutura tridimensional

Country Status (16)

Country Link
US (2) US11046930B2 (pt)
EP (2) EP3670155A1 (pt)
JP (4) JP6550379B2 (pt)
KR (2) KR102450885B1 (pt)
CN (1) CN105579219B (pt)
AU (1) AU2014280825B2 (pt)
BR (1) BR112015031320B1 (pt)
CA (1) CA2915737C (pt)
DK (1) DK3007882T3 (pt)
ES (1) ES2770418T3 (pt)
IL (1) IL243014B (pt)
PL (1) PL3007882T3 (pt)
PT (1) PT3007882T (pt)
RU (1) RU2643138C2 (pt)
SG (1) SG11201510138RA (pt)
WO (1) WO2014197999A1 (pt)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9172829B2 (en) * 2012-07-31 2015-10-27 Makerbot Industries, Llc Three-dimensional printer with laser line scanner
EP3670155A1 (en) 2013-06-13 2020-06-24 Aspect Biosystems Ltd. System for additive manufacturing of three-dimensional structures and method for same
US11903612B2 (en) * 2013-11-04 2024-02-20 University Of Iowa Research Foundation Bioprinter and methods of using same
EP3536377A1 (en) 2014-02-26 2019-09-11 Luma Therapeutics, Inc. Ultraviolet phototherapy apparatus
US20160318260A1 (en) * 2015-04-30 2016-11-03 Elwha Llc Printing systems and related methods
DE102015206813A1 (de) * 2015-04-15 2016-10-20 Robert Bosch Gmbh Vorrichtung und Verfahren zum Auftragen eines Fluids auf einen Werkstückträger zum Erzeugen eines Werkstücks und System zum Erzeugen eines Werkstücks
EP3289065B1 (en) * 2015-04-29 2019-01-23 Politecnico di Milano Microfluidic device and relative method for the generation and/or culture and/or maturation of three- dimensional cell and/or tissue constructs
JP7026040B2 (ja) * 2015-06-16 2022-02-25 アスペクト バイオシステムズ リミティド 連続的にバイオプリントされた多層組織構造体
JP2018535310A (ja) 2015-09-16 2018-11-29 アプライド マテリアルズ インコーポレイテッドＡｐｐｌｉｅｄ Ｍａｔｅｒｉａｌｓ，Ｉｎｃｏｒｐｏｒａｔｅｄ 付加製造システムのためのプリントヘッドモジュール
EP3349969A4 (en) * 2015-09-16 2019-05-22 Applied Materials, Inc. PRINTING HEAD MODULE NETWORK FOR ADDITIVE MANUFACTURING SYSTEM
AU2016363000B2 (en) 2015-12-04 2020-01-23 EMULATE, Inc. Open-top microfluidic device with structural anchors
US10026674B2 (en) 2015-12-22 2018-07-17 Raytheon Company Cooling structure for integrated circuits and methods for forming such structure
US11465346B2 (en) 2015-12-30 2022-10-11 Revotek Co., Ltd Bioprinter spray head assembly and bioprinter
EP3409454B1 (en) * 2016-01-25 2023-03-01 Ricoh Company, Ltd. Three-dimensional molded object, method for producing three-dimensional molded object, material set for three-dimensional molding, and hydrogel precursor liquid
WO2017139514A1 (en) 2016-02-09 2017-08-17 Luma Therapeutics, Inc. Methods, compositions and apparatuses for treating psoriasis by phototherapy
WO2017149451A2 (en) 2016-02-29 2017-09-08 Verity Studios Ag Systems and methods for charging, transporting, and operating flying machines
WO2017192004A1 (ko) * 2016-05-03 2017-11-09 주식회사 티앤알바이오팹 삼차원 프린팅용 잉크를 공급하는 방법 및 이를 이용한 삼차원 프린팅 방법
KR20170124972A (ko) 2016-05-03 2017-11-13 주식회사 티앤알바이오팹 삼차원 프린팅용 잉크를 공급하는 방법 및 이를 이용한 삼차원 프린팅 방법
US10926454B2 (en) * 2016-05-20 2021-02-23 Sartorius Stedim Biotech Gmbh Dispensing device and system for biological products
GB201609764D0 (en) * 2016-06-03 2016-07-20 Isis Innovation 3D printing of gel networks
KR20190028433A (ko) * 2016-06-16 2019-03-18 애스펙트 바이오시스템즈 리미티드 바이오프린팅된 반월판 임플란트 및 이를 사용하는 방법
US10073346B2 (en) 2016-07-08 2018-09-11 Cypre, Inc. Apparatus for patterning hydrogels into multi-well plates
US10345208B2 (en) 2016-07-12 2019-07-09 Deka Products Limited Partnership System and method for applying force to a device
US11254901B2 (en) 2016-07-12 2022-02-22 Deka Products Limited Partnership System and method for printing tissue
USD812766S1 (en) * 2016-07-12 2018-03-13 EMULATE, Inc. Microfluidic chip for use with a fluid perfusion module
US11498332B2 (en) * 2016-07-27 2022-11-15 President And Fellows Of Harvard College Apparatus and method for acoustophoretic printing
WO2018039533A1 (en) * 2016-08-26 2018-03-01 The Government Of The United States Of America As Represented By The Secretary Of The Navy Tailored multi-material delivery for direct-write manufacturing
USD816861S1 (en) * 2016-09-07 2018-05-01 EMULATE, Inc. Transparent microfluidic chip without pressure features for use with a fluid perfusion module
USD842493S1 (en) * 2016-09-07 2019-03-05 EMULATE, Inc. Microfluidic chip without pressure features for use with a fluid perfusion module
US11299705B2 (en) 2016-11-07 2022-04-12 Deka Products Limited Partnership System and method for creating tissue
DE102016225227A1 (de) * 2016-12-16 2018-06-21 Robert Bosch Gmbh Verfahren und Vorrichtung zum additiven Fertigen eines dreidimensionalen Objekts sowie dreidimensionales Objekt
CN106510898A (zh) * 2016-12-21 2017-03-22 中国人民大学 一种基于多通道喷嘴的多组分三维生物打印装置和方法
JP6861408B2 (ja) * 2016-12-27 2021-04-21 東京応化工業株式会社 細胞培養用チップの製造方法
SG11201908329QA (en) * 2017-03-15 2019-10-30 Aspect Biosystems Ltd Systems and methods for printing a fiber structure
CN106926456B (zh) * 2017-04-22 2018-12-28 广东工业大学 一种支架充液辅助成型系统
SG11201910191RA (en) 2017-05-11 2019-11-28 Univ King Abdullah Sci & Tech A peptide capable of forming a gel for use in tissue engineering and bioprinting
KR102418307B1 (ko) * 2017-05-11 2022-07-06 킹 압둘라 유니버시티 오브 사이언스 앤드 테크놀로지 미세유체공학-기반 3d 바이오프린팅용 장치 및 방법
AU2018268713B2 (en) 2017-05-16 2024-04-18 Embody Inc. Biopolymer compositions, scaffolds and devices
WO2018226642A1 (en) * 2017-06-06 2018-12-13 Organofab Technologies, Inc. Method and apparatus for a tissue engineering system
GB201710834D0 (en) 2017-07-05 2017-08-16 Univ Newcastle Printing apparatus and method
US10570362B2 (en) 2017-07-12 2020-02-25 Deka Products Limited Partnership System and method for transferring tissue
FR3069806B1 (fr) * 2017-08-03 2019-08-23 Centre National De La Recherche Scientifique Tete d'impression d'une imprimante, imprimante et procede d'impression
WO2019084209A1 (en) 2017-10-24 2019-05-02 Embody Llc BIOPOLYMER SCAFFOLDING IMPLANTS AND METHODS OF MAKING SAME
WO2019094792A1 (en) 2017-11-10 2019-05-16 Local Motors IP, LLC Additive manufactured structure and method for making the same
SE1850073A1 (en) * 2018-01-24 2019-07-25 Cellink Ab 3D bioprinters
CN110339469A (zh) * 2018-04-08 2019-10-18 上海叁钛生物科技有限公司 皮肤原位打印用打印头装置
US11731342B2 (en) 2018-04-23 2023-08-22 Rapidflight Holdings, Llc Additively manufactured structure and method for making the same
KR20200123212A (ko) 2018-04-23 2020-10-28 로컬 모터스 아이피, 엘엘씨 적층 제조를 위한 방법 및 장치
DE102018111751A1 (de) * 2018-05-16 2019-11-21 Cellbricks Gmbh Verfahren zur Herstellung eines Zellkultureinsatzes mit mindestens einer Membran
GB201810447D0 (en) * 2018-06-26 2018-08-08 Univ Leuven Kath Photopolymerised cell culture devices
CA3112940A1 (en) * 2018-09-19 2020-03-26 Aspect Biosystems Ltd. Systems and methods for printing a core fiber
JP2022511527A (ja) * 2018-12-06 2022-01-31 インベンティア ライフ サイエンス プロプライアタリー リミティド ３ｄバイオプリンタ用のプリントヘッドアセンブリ
CN113874192B (zh) 2019-02-01 2024-01-02 恩博迪股份有限公司 微流体挤出
US11699272B2 (en) 2019-03-29 2023-07-11 Hewlett-Packard Development Company, L.P. Generating fluidic components
US11813790B2 (en) 2019-08-12 2023-11-14 Rapidflight Holdings, Llc Additively manufactured structure and method for making the same
WO2021029868A1 (en) * 2019-08-12 2021-02-18 Local Motors IP, LLC Additively manufactured structure and method for making the same
US11083830B2 (en) * 2019-10-14 2021-08-10 Fresenius Medical Care Holdings, Inc. Implantable fluid conduit
EP4051487A4 (en) * 2019-11-01 2023-11-22 Aspect Biosystems Ltd. SYSTEMS AND METHODS FOR PRINTING CORE-SHELL FIBER
KR102210626B1 (ko) * 2020-02-28 2021-02-02 (주)케이랩스 공기압을 이용한 3d 프린팅 장치
MX2023000137A (es) * 2020-06-25 2023-04-11 Dloc Biosystems Inc Organoide de conducto en chip.
AT523819B1 (de) * 2020-07-03 2021-12-15 Charlotte Ohonin Kultivierungsvorrichtung für ein Kulitivieren von Zellkulturen
US11673324B2 (en) 2020-08-20 2023-06-13 King Abdullah University Of Science And Technology Nozzle for 3D bioprinting
WO2022038552A1 (en) * 2020-08-20 2022-02-24 King Adbullah University Of Science And Technology Nozzle for 3d bioprinting
EP4232558A1 (en) * 2020-10-21 2023-08-30 King Abdullah University Of Science And Technology Delivery of endothelial cell-laden microgel elicits angiogenesis in self-assembling ultrashort peptide hydrogels
CN112549532A (zh) * 2020-12-08 2021-03-26 南通大学 一种基于3d打印装置的微流控芯片制备方法
WO2022134912A1 (zh) * 2020-12-25 2022-06-30 湖州艾先特电子科技有限公司 一种适用于3d生物打印机上料的搅拌机构
US11628600B2 (en) 2021-05-21 2023-04-18 Saudi Arabian Oil Company Fabrication method of transparent 3D polydimethylsiloxane devices with polycaprolactone molds
CN113500773B (zh) * 2021-07-08 2022-04-01 吉林大学 仿龙虾眼聚焦脉冲强光原位成型4d打印装置及方法
WO2023108302A1 (en) * 2021-12-16 2023-06-22 Aspect Biosystems Ltd. Radial pump assembly and methods of using same

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292472A (en) 1992-12-18 1994-03-08 Bridgestone Corporation Coextrusion apparatus and method with rotating cord guidance
US7033603B2 (en) 1999-08-06 2006-04-25 Board Of Regents The University Of Texas Drug releasing biodegradable fiber for delivery of therapeutics
WO2005057436A1 (en) 2003-11-14 2005-06-23 Drexel University Method and apparatus for computer-aided tissue engineering for modeling, design and freeform fabrication of tissue scaffolds, constructs, and devices
US8241905B2 (en) 2004-02-24 2012-08-14 The Curators Of The University Of Missouri Self-assembling cell aggregates and methods of making engineered tissue using the same
US7939003B2 (en) 2004-08-11 2011-05-10 Cornell Research Foundation, Inc. Modular fabrication systems and methods
US8398935B2 (en) 2005-06-09 2013-03-19 The United States Of America, As Represented By The Secretary Of The Navy Sheath flow device and method
EP1790861A1 (en) 2005-11-25 2007-05-30 Bonsens AB Microfluidic system
JP2008017798A (ja) * 2006-07-14 2008-01-31 Olympus Corp 生体組織製造装置および生体組織製造方法
US8047235B2 (en) * 2006-11-30 2011-11-01 Alcatel Lucent Fluid-permeable body having a superhydrophobic surface
US7771183B2 (en) * 2007-01-17 2010-08-10 3D Systems, Inc. Solid imaging system with removal of excess uncured build material
GB0722092D0 (en) 2007-11-09 2007-12-19 Q Chip Ltd Microfluidic device and method for producing sheathed flow
SG188832A1 (en) 2008-02-29 2013-04-30 Agency Science Tech & Res Hydrodynamic spinning of polymer fiber in coaxial laminar flows
KR101004769B1 (ko) * 2008-09-09 2011-01-04 서울대학교산학협력단 광유체적 리소그래피 시스템 및 마이크로구조물 제조방법
JP2012510268A (ja) 2008-12-02 2012-05-10 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 同軸上にカプセル化された細胞分散物及びマイクロ組織
US20110136162A1 (en) 2009-08-31 2011-06-09 Drexel University Compositions and Methods for Functionalized Patterning of Tissue Engineering Substrates Including Bioprinting Cell-Laden Constructs for Multicompartment Tissue Chambers
JP5633077B2 (ja) 2009-10-14 2014-12-03 国立大学法人 東京大学 被覆されたマイクロゲルファイバ
RU2573409C2 (ru) * 2009-11-04 2016-01-20 Дзе Юниверсити Оф Бритиш Коламбиа Содержащие нуклеиновые кислоты липидные частицы и относящиеся к ним способы
EP3045148B1 (en) * 2009-12-30 2018-11-14 Synthes GmbH Intergrated multi-material implants and methods of manufacture
WO2012009363A1 (en) 2010-07-12 2012-01-19 President And Fellows Of Harvard College Alginate hydrogel fibers and related materials
US20120089238A1 (en) 2010-10-06 2012-04-12 Hyun-Wook Kang Integrated organ and tissue printing methods, system and apparatus
JP2013542728A (ja) 2010-10-21 2013-11-28 オルガノボ，インク． 組織の作成のための、デバイス、システム、および方法
KR101222890B1 (ko) 2010-11-24 2013-01-17 고려대학교 산학협력단 표면 장력을 이용한 마이크로 밸브 및 이를 포함하는 미세유체칩, 및 이의 제조방법
US20140179021A1 (en) * 2010-12-06 2014-06-26 University Of South Australia High throughput microfluidic device
US9126366B2 (en) 2011-06-15 2015-09-08 Korea Institute Of Machinery & Materials Apparatus and method for manufacturing cell culture scaffold
US9499779B2 (en) * 2012-04-20 2016-11-22 Organovo, Inc. Devices, systems, and methods for the fabrication of tissue utilizing UV cross-linking
US20140232035A1 (en) * 2013-02-19 2014-08-21 Hemant Bheda Reinforced fused-deposition modeling
US9579851B2 (en) * 2013-03-22 2017-02-28 Markforged, Inc. Apparatus for fiber reinforced additive manufacturing
EP3670155A1 (en) 2013-06-13 2020-06-24 Aspect Biosystems Ltd. System for additive manufacturing of three-dimensional structures and method for same
US11903612B2 (en) 2013-11-04 2024-02-20 University Of Iowa Research Foundation Bioprinter and methods of using same
US20160297104A1 (en) * 2013-11-19 2016-10-13 Guill Tool & Engineering Coextruded, multilayer and multicomponent 3d printing inputs field

Also Published As

Publication number Publication date
CN105579219B (zh) 2017-09-01
JP2020182474A (ja) 2020-11-12
JP6550379B2 (ja) 2019-07-24
US11046930B2 (en) 2021-06-29
US20210317404A1 (en) 2021-10-14
PT3007882T (pt) 2020-02-20
BR112015031320B1 (pt) 2022-01-18
EP3670155A1 (en) 2020-06-24
US11738501B2 (en) 2023-08-29
DK3007882T3 (da) 2020-02-24
SG11201510138RA (en) 2016-01-28
ES2770418T3 (es) 2020-07-01
RU2643138C2 (ru) 2018-01-30
CA2915737A1 (en) 2014-12-18
CA2915737C (en) 2016-09-13
EP3007882B1 (en) 2019-11-20
JP2023061953A (ja) 2023-05-02
WO2014197999A1 (en) 2014-12-18
JP6733014B2 (ja) 2020-07-29
KR20210097816A (ko) 2021-08-09
EP3007882A4 (en) 2017-03-22
KR102450885B1 (ko) 2022-10-06
CN105579219A (zh) 2016-05-11
JP2019201644A (ja) 2019-11-28
JP2016530874A (ja) 2016-10-06
IL243014B (en) 2019-08-29
EP3007882A1 (en) 2016-04-20
AU2014280825A1 (en) 2016-01-28
KR20160030939A (ko) 2016-03-21
KR102284531B1 (ko) 2021-08-03
US20160136895A1 (en) 2016-05-19
JP7217248B2 (ja) 2023-02-02
RU2016100442A (ru) 2017-07-18
PL3007882T3 (pl) 2020-06-01
AU2014280825B2 (en) 2018-01-04

Similar Documents

Publication Publication Date Title
BR112015031320A2 (pt) sistema para produção de aditivo de estruturas tridimensionais e método para a mesma
BR112017015759A2 (pt) cartucho para uso em um sistema de fornecimento de vapor, sistema de fornecimento de vapor
BR112018074421A2 (pt) cartucho de célula de fluxo com suporte de selo flutuante
BR112018068197A2 (pt) utilização de areia de fraturamento úmida para operações de fraturamento hidráulico
BR112015029518A2 (pt) processo para a preparação de um composto orgânico de metal
EP3033599A4 (en) Methods of improving accuracy and precision of droplet metering using an on-actuator reservoir as the fluid input
BR112013029177A2 (pt) sistema de injeção fluido que tem vários sistemas para controlar um procedimento de injeção
BR112013016252A2 (pt) sistema de geração de aerossol que tem um meio para determinar o esgotamento de um substrato líquido
BR112014019091A8 (pt) Elemento filtrante plano, dispositivo de filtração, método de produzir um elemento filtrante plano e uso de um elemento filtrante plano
BR112015001221A2 (pt) sistema, e, métodos para monitorar um fluido e a qualidade de um fluido.
BR112016005572A8 (pt) sistema para processar pelo menos fluidos de reservatório dentro de um furo de poço que está disposto no interior de um reservatório de petróleo, separador para efetuar a separação de materiais de fluido de reservatório, processo para produzir material de fluido de hidrocarboneto e uso do sistema para processar pelo menos fluidos de reservatório
BR112016017105A2 (pt) válvula de microfluidos.
WO2013160408A3 (en) Microfluidic device for performing operations on microdroplets
BR112015012128A2 (pt) reservatório de fluido para um dispositivo de geração de aerossol, combinação de reservatório de fluido e embalagem primária de fluido, e dispositivo de geração de aerossol para uso com o reservatório de fluido
BR112015022789A2 (pt) método para detectar pelo menos um composto presente em fluidos
BR112015006273A2 (pt) ''método de prognóstico, kit que compreende reagentes, agente quimioterápico citotóxico terapêutico, uso de um agente quimioterápico citotóxico terapêutico, sistema para prognóstico de sobrevivência global e meio legível por computador''
BR112013026472A2 (pt) sistema de recarga de fluido
MX361374B (es) Cabezal de corte mejorado y su uso.
BR112015009110A2 (pt) sensor de fluido, e, método para uso na fabricação de um sensor de fluido.
GB2526999A (en) Capillary barriers for staged loading of microfluidic devices
AR085289A1 (es) Montaje de valvula de solenoide para un sistema dosificador
BR112017019338A2 (pt) fluidos de segregação, métodos de fabricação e métodos de uso
WO2015047502A3 (en) Systems, apparatus, and methods for droplet-based microfluidics cell poration
AR098332A1 (es) Método de control de inyección de fluidos líquidos en reservorios de petróleo y gas, y regulador de flujo ajustable para inyección de fluidos en reservorios de petróleo y gas
BR112017026602A2 (pt) dispositivo microfluídico

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 13/06/2014, OBSERVADAS AS CONDICOES LEGAIS.