BR112015006273A2 - ''método de prognóstico, kit que compreende reagentes, agente quimioterápico citotóxico terapêutico, uso de um agente quimioterápico citotóxico terapêutico, sistema para prognóstico de sobrevivência global e meio legível por computador'' - Google Patents

''método de prognóstico, kit que compreende reagentes, agente quimioterápico citotóxico terapêutico, uso de um agente quimioterápico citotóxico terapêutico, sistema para prognóstico de sobrevivência global e meio legível por computador''

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Publication number
BR112015006273A2
BR112015006273A2 BR112015006273A BR112015006273A BR112015006273A2 BR 112015006273 A2 BR112015006273 A2 BR 112015006273A2 BR 112015006273 A BR112015006273 A BR 112015006273A BR 112015006273 A BR112015006273 A BR 112015006273A BR 112015006273 A2 BR112015006273 A2 BR 112015006273A2
Authority
BR
Brazil
Prior art keywords
chemotherapeutic agent
cytotoxic chemotherapeutic
therapeutic cytotoxic
prognostic
reagents
Prior art date
Application number
BR112015006273A
Other languages
English (en)
Inventor
De Reynies Aurélien
Nault Jean-Charles
Zucman-Rossi Jessica
Laurent-Puig Pierre
Original Assignee
Inst Nat Sante Rech Med
Integragen Sa
Univ Paris Descartes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med, Integragen Sa, Univ Paris Descartes filed Critical Inst Nat Sante Rech Med
Publication of BR112015006273A2 publication Critical patent/BR112015006273A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medical Informatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Data Mining & Analysis (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Databases & Information Systems (AREA)
  • Artificial Intelligence (AREA)
  • Evolutionary Computation (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Bioethics (AREA)
  • Software Systems (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Primary Health Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BR112015006273A 2012-09-21 2013-09-23 ''método de prognóstico, kit que compreende reagentes, agente quimioterápico citotóxico terapêutico, uso de um agente quimioterápico citotóxico terapêutico, sistema para prognóstico de sobrevivência global e meio legível por computador'' BR112015006273A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261704360P 2012-09-21 2012-09-21
EP12306146 2012-09-21
PCT/EP2013/069753 WO2014044854A1 (en) 2012-09-21 2013-09-23 A method for prognosis of global survival and survival without relapse in hepatocellular carcinoma

Publications (1)

Publication Number Publication Date
BR112015006273A2 true BR112015006273A2 (pt) 2017-07-04

Family

ID=47044928

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015006273A BR112015006273A2 (pt) 2012-09-21 2013-09-23 ''método de prognóstico, kit que compreende reagentes, agente quimioterápico citotóxico terapêutico, uso de um agente quimioterápico citotóxico terapêutico, sistema para prognóstico de sobrevivência global e meio legível por computador''

Country Status (8)

Country Link
US (1) US20150232944A1 (pt)
EP (1) EP2898094A1 (pt)
JP (1) JP2015535176A (pt)
CN (1) CN104769131A (pt)
AU (1) AU2013320166A1 (pt)
BR (1) BR112015006273A2 (pt)
CA (1) CA2885518A1 (pt)
WO (1) WO2014044854A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018189215A1 (en) * 2017-04-12 2018-10-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for predicting the survival time of a patient suffering from hepatocellular carcinoma
CN109642258B (zh) * 2018-10-17 2020-06-09 上海允英医疗科技有限公司 一种肿瘤预后预测的方法和系统
JP2022523564A (ja) 2019-03-04 2022-04-25 アイオーカレンツ， インコーポレイテッド 機械学習を使用するデータ圧縮および通信
CN110634571A (zh) * 2019-09-20 2019-12-31 四川省人民医院 肝移植术后预后预测系统
CN110647136B (zh) * 2019-09-29 2021-01-05 华东交通大学 一种牵引电机驱动系统复合故障检测与分离方法
CN111458509B (zh) * 2020-04-14 2023-09-22 中国人民解放军海军军医大学第三附属医院 肝细胞癌预后评估的生物标志物及其试剂盒和方法
CN111402949B (zh) * 2020-04-17 2023-12-22 北京恩瑞尼生物科技股份有限公司 一种肝细胞肝癌患者诊断、预后和复发统一模型的构建方法
CN114107511B (zh) * 2022-01-10 2023-10-20 深圳市龙华区人民医院 预测肝癌预后的标志物组合及其应用
CN114592065B (zh) * 2022-04-21 2023-12-12 青岛市市立医院 一组预测肝癌预后联合标志物及其应用
CN115439473B (zh) * 2022-11-04 2023-04-07 北京精诊医疗科技有限公司 一种基于交互分组注意机制的多期相占位分类方法
CN115564770B (zh) * 2022-11-11 2023-04-18 北京精诊医疗科技有限公司 一种基于深度卷积网络模型的多期相占位分类方法
CN116543866B (zh) * 2023-03-27 2023-12-19 中国医学科学院肿瘤医院 一种镇痛泵止痛预测模型的生成和使用方法
CN117334325B (zh) * 2023-09-26 2024-04-16 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） 一种lcat在肝细胞癌诊断、治疗和预测复发的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050089895A1 (en) * 2003-08-13 2005-04-28 Cheung Siu T. Compositions and methods for prognosis and therapy of liver cancer
EP1830289A1 (en) * 2005-11-30 2007-09-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) Methods for hepatocellular carninoma classification and prognosis

Also Published As

Publication number Publication date
AU2013320166A1 (en) 2015-03-19
US20150232944A1 (en) 2015-08-20
WO2014044854A1 (en) 2014-03-27
CN104769131A (zh) 2015-07-08
EP2898094A1 (en) 2015-07-29
JP2015535176A (ja) 2015-12-10
CA2885518A1 (en) 2014-03-27

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]