BR112015014654A2 - solubilizado de curcumina - Google Patents
solubilizado de curcuminaInfo
- Publication number
- BR112015014654A2 BR112015014654A2 BR112015014654A BR112015014654A BR112015014654A2 BR 112015014654 A2 BR112015014654 A2 BR 112015014654A2 BR 112015014654 A BR112015014654 A BR 112015014654A BR 112015014654 A BR112015014654 A BR 112015014654A BR 112015014654 A2 BR112015014654 A2 BR 112015014654A2
- Authority
- BR
- Brazil
- Prior art keywords
- polysorbate
- curcumin
- solubilized
- weight
- equal
- Prior art date
Links
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 title abstract 8
- 229940109262 curcumin Drugs 0.000 title abstract 4
- 235000012754 curcumin Nutrition 0.000 title abstract 4
- 239000004148 curcumin Substances 0.000 title abstract 4
- VFLDPWHFBUODDF-UHFFFAOYSA-N diferuloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(=O)CC(=O)C=CC=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-UHFFFAOYSA-N 0.000 title abstract 4
- 229920001213 Polysorbate 20 Polymers 0.000 abstract 2
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 abstract 2
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 abstract 2
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 abstract 2
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 abstract 2
- 229940068977 polysorbate 20 Drugs 0.000 abstract 2
- 229920000053 polysorbate 80 Polymers 0.000 abstract 2
- 229940068968 polysorbate 80 Drugs 0.000 abstract 2
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 239000000693 micelle Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D7/00—Edible oil or fat compositions containing an aqueous phase, e.g. margarines
- A23D7/005—Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by ingredients other than fatty acid triglycerides
- A23D7/0053—Compositions other than spreads
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/56—Flavouring or bittering agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/121—Ketones acyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/10—Natural spices, flavouring agents or condiments; Extracts thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
- A23L5/40—Colouring or decolouring of foods
- A23L5/42—Addition of dyes or pigments, e.g. in combination with optical brighteners
- A23L5/43—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/20—Natural extracts
- A23V2250/21—Plant extracts
- A23V2250/2112—Curcumin, turmeric
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Mycology (AREA)
- Botany (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Emergency Medicine (AREA)
- Birds (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1/1 resumo "solubilizado de curcumina" a presente invenção refere-se a um solubilizado, consistindo de curcumina com uma percentagem inferior a ou igual a 10 % em peso, de preferência, inferior a ou igual a 7,5 % em peso, de preferência especial, de 6 % em peso, e pelo menos um emulsificador com um valor hlb na faixa entre 13 e 18, especialmente polisorbato 80 ou po-lisorbato 20 ou uma mistura de polisorbato 20 e polisor-bato 80, sendo que o diâmetro médio das micelas carrega-das de curcumina situa-se entre 5 nm e 40 nm, de prefe-rência, entre 6 nm e 20 nm, de preferência especial, en-tre 7 nm e 10 nm.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE202012012130.8U DE202012012130U1 (de) | 2012-12-19 | 2012-12-19 | Curcuminsolubilisat |
| DE202012012130.8. | 2012-12-19 | ||
| PCT/EP2013/001427 WO2014094921A1 (de) | 2012-12-19 | 2013-05-15 | Curcuminsolubilisat |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112015014654A2 true BR112015014654A2 (pt) | 2017-07-11 |
| BR112015014654B1 BR112015014654B1 (pt) | 2020-08-18 |
Family
ID=48628594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015014654-6A BR112015014654B1 (pt) | 2012-12-19 | 2013-05-15 | Formulação de curcumina micelar, cápsula e fluido contendo a dita formulação |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US11311483B2 (pt) |
| EP (1) | EP2934185B1 (pt) |
| JP (1) | JP6324989B2 (pt) |
| KR (2) | KR20180007005A (pt) |
| CN (2) | CN109330980B (pt) |
| BR (1) | BR112015014654B1 (pt) |
| CY (1) | CY1118432T1 (pt) |
| DE (1) | DE202012012130U1 (pt) |
| DK (1) | DK2934185T3 (pt) |
| ES (1) | ES2609504T3 (pt) |
| HK (1) | HK1211801A1 (pt) |
| MY (1) | MY175753A (pt) |
| PL (1) | PL2934185T3 (pt) |
| PT (1) | PT2934185T (pt) |
| RS (1) | RS55490B1 (pt) |
| RU (1) | RU2615815C2 (pt) |
| SI (1) | SI2934185T1 (pt) |
| UA (1) | UA113573C2 (pt) |
| WO (1) | WO2014094921A1 (pt) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108697668B (zh) * | 2015-08-28 | 2022-11-04 | 康霈生技股份有限公司 | 用于减少局部脂肪的医药组成物及其用途 |
| JP2019517574A (ja) * | 2016-04-07 | 2019-06-24 | メドクリア ヘルスケア プライベート リミテッドＭｅｄｃｌｅａｒ Ｈｅａｌｔｈｃａｒｅ Ｐｒｉｖａｔｅ Ｌｉｍｉｔｅｄ | クルクミノイドの水溶調製（液体）及びそのプロセス |
| CA3027450C (en) * | 2016-06-14 | 2023-08-29 | Aquanova Ag | Resveratrol solubilisation product |
| HUE049304T2 (hu) * | 2016-06-14 | 2020-09-28 | Aquanova Ag | Rezveratrol szolubilizációs termék gyógyászati célokra |
| EP3290026A1 (en) | 2016-09-06 | 2018-03-07 | Athenion AG | Method for solubilizing poorly water-soluble dietary supplements and pharmaceutically active agents |
| IT201700045343A1 (it) * | 2017-04-26 | 2018-10-26 | Micro Sphere Sa | Processo per la preparazione di un integratore alimentare e integratore così ottenuto |
| KR102573152B1 (ko) * | 2017-07-11 | 2023-09-01 | 아쿠아노바 아게 | 커큐민 및 선택적으로 적어도 1종의 다른 활성 물질을 갖는 가용화물 |
| WO2019011414A1 (de) * | 2017-07-11 | 2019-01-17 | Aquanova Ag | Solubilisat mit curcumin und boswellia |
| CN111163806A (zh) | 2017-07-11 | 2020-05-15 | 阿奎诺瓦股份公司 | 含有姜黄素，乳香和黄腐酚的增溶物 |
| WO2019011415A1 (de) * | 2017-07-11 | 2019-01-17 | Aquanova Ag | SOLUBILISAT MIT CURCUMIN, XANTHOHUMOL UND SÜßHOLZWURZELEXTRAKT |
| EP3511325A1 (en) | 2018-01-11 | 2019-07-17 | MetrioPharm AG | Method for solubilizing 5-amino-2,3-dihydro-1,4-phthalazinedione |
| DE102018101778A1 (de) * | 2018-01-26 | 2019-08-01 | Lts Lohmann Therapie-Systeme Ag | Mehrschichtiger Oraler Dünnfilm |
| EP3536332A1 (en) | 2018-03-07 | 2019-09-11 | Athenion AG | Krill oil for solubilizing poorly water-soluble dietary supplements and pharmaceutically active agents |
| DK3820527T3 (da) | 2018-07-11 | 2023-09-25 | Aquanova Ag | Xanthohumol-solubilisat |
| BR112020026362A2 (pt) * | 2018-07-11 | 2021-03-30 | Aquanova Ag | Solubilizado com curcumina e pelo menos um canabinoide como uma substância ativa adicional |
| WO2020011402A1 (de) * | 2018-07-11 | 2020-01-16 | Aquanova Ag | Xanthohumol-solubilisat |
| TR201910337A2 (tr) | 2019-07-10 | 2021-01-21 | Mehmet Nevzat Pisak | Yüksek çözünürlüğe ve bi̇yoyararlanima sahi̇p kurkumi̇noi̇d oral bi̇leşi̇mleri̇ |
| US20210060166A1 (en) * | 2019-07-29 | 2021-03-04 | Horacio Astudillo de la Vega | Method for the preparation of a 1,7-bis (4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione system in polysorbates for the formation of micelles in an aqueous medium aimed at the properties of the bioavailability of curcuminoids |
| DE202019104734U1 (de) * | 2019-08-29 | 2020-12-01 | Aquanova Ag | Folsäure-Solubilisat |
| AU2020366237A1 (en) * | 2019-10-18 | 2022-04-14 | Quicksilver Scientific, Inc. | Self-microemulsifying multi-deliverable systems |
| EP4090173A1 (de) * | 2020-01-13 | 2022-11-23 | Rrw B.V. | Wässrige lösung einer lipophilen verbindung |
| EP3919046A1 (en) | 2020-06-02 | 2021-12-08 | Athenion AG | Method for solubilizing natural, endogenous and synthetic cannabinoids |
| EP4186497A1 (en) | 2021-11-26 | 2023-05-31 | Dorian Bevec | Alpha lipoic acid, epigallocatechin 3-gallate, and curcumin as a medicament for the treatment of arthritis or sars-cov-2 infection |
| WO2024057288A1 (en) | 2022-09-16 | 2024-03-21 | Bausch Health Ireland Limited | Methods for treating acne and skin oiliness with tazarotene |
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| DE10133305B4 (de) | 2001-07-12 | 2004-06-03 | Aquanova German Solubilisate Technologies (Agt) Gmbh | Ubichinon Konzentrat |
| DE10158447B4 (de) * | 2001-11-30 | 2005-02-10 | Aquanova German Solubilisate Technologies (Agt) Gmbh | Ascorbinsäure-Solubilisat |
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| CN101361713B (zh) * | 2008-09-08 | 2010-08-25 | 山东大学 | 姜黄素纳米结晶制剂的制备方法 |
| CN102202652A (zh) | 2008-11-17 | 2011-09-28 | 莱拉制药用品私营有限责任公司 | 一种使姜黄素及其衍生物进行纳米乳化的方法 |
| AU2009329035A1 (en) * | 2008-12-01 | 2011-06-23 | Laila Pharmaceuticals Pvt. Ltd. | Topical formulation(s) for the treatment of inflammation, skin and mucosal disorders and other diseases thereof |
| ES2602812T3 (es) * | 2008-12-01 | 2017-02-22 | Aquanova Ag | Protección contra la oxidación integrada micelarmente para colorantes naturales |
| CN102405046B (zh) * | 2009-03-20 | 2014-07-02 | 百欧特瑞股份公司 | 表现出抗炎性质的药物组合物 |
| EP2410999A4 (en) * | 2009-03-23 | 2012-04-18 | Laila Pharmaceuticals Pvt Ltd | CURCUMINOIDS AND THEIR METABOLIC PRODUCTS FOR ALLERGIC EYE / NOSIS DISEASES |
| JP2010265223A (ja) | 2009-05-15 | 2010-11-25 | National Cardiovascular Center | 嫌気性発酵抑制剤 |
| DE202009016292U1 (de) * | 2009-12-01 | 2011-04-07 | Aquanova Ag | Als Emulgator wirkende Zusammensetzung für wasserlösliche Solubilisate hydrophober Verbindungen |
| US8835509B2 (en) * | 2010-05-31 | 2014-09-16 | Arbro Pharmaceuticals Ltd. | Self emulsifying drug delivery system for a curcuminoid based composition |
| CA2828253C (en) | 2011-02-25 | 2016-10-18 | South Dakota State University | Polymer conjugated protein micelles |
| CN103491964A (zh) * | 2011-03-08 | 2014-01-01 | 扎里卡斯药品有限公司 | 固体分散体制剂及其使用方法 |
-
2012
- 2012-12-19 DE DE202012012130.8U patent/DE202012012130U1/de not_active Expired - Lifetime
-
2013
- 2013-05-15 RU RU2015129577A patent/RU2615815C2/ru active
- 2013-05-15 PL PL13729247T patent/PL2934185T3/pl unknown
- 2013-05-15 WO PCT/EP2013/001427 patent/WO2014094921A1/de active Application Filing
- 2013-05-15 JP JP2015548242A patent/JP6324989B2/ja active Active
- 2013-05-15 DK DK13729247.0T patent/DK2934185T3/en active
- 2013-05-15 KR KR1020187000630A patent/KR20180007005A/ko not_active Application Discontinuation
- 2013-05-15 CN CN201811453446.4A patent/CN109330980B/zh active Active
- 2013-05-15 UA UAA201507032A patent/UA113573C2/uk unknown
- 2013-05-15 US US14/653,560 patent/US11311483B2/en active Active
- 2013-05-15 EP EP13729247.0A patent/EP2934185B1/de active Active
- 2013-05-15 CN CN201380067238.XA patent/CN104902765A/zh active Pending
- 2013-05-15 PT PT137292470T patent/PT2934185T/pt unknown
- 2013-05-15 MY MYPI2015702012A patent/MY175753A/en unknown
- 2013-05-15 BR BR112015014654-6A patent/BR112015014654B1/pt active IP Right Grant
- 2013-05-15 RS RS20161168A patent/RS55490B1/sr unknown
- 2013-05-15 KR KR1020157016542A patent/KR101983332B1/ko active IP Right Grant
- 2013-05-15 SI SI201330471A patent/SI2934185T1/sl unknown
- 2013-05-15 ES ES13729247.0T patent/ES2609504T3/es active Active
-
2015
- 2015-11-09 HK HK15111002.6A patent/HK1211801A1/xx unknown
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2017
- 2017-01-05 CY CY20171100017T patent/CY1118432T1/el unknown
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2022
- 2022-03-18 US US17/698,389 patent/US20220202713A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| UA113573C2 (xx) | 2017-02-10 |
| EP2934185B1 (de) | 2016-10-12 |
| US20220202713A1 (en) | 2022-06-30 |
| WO2014094921A1 (de) | 2014-06-26 |
| KR101983332B1 (ko) | 2019-09-03 |
| EP2934185A1 (de) | 2015-10-28 |
| RU2615815C2 (ru) | 2017-04-11 |
| PT2934185T (pt) | 2017-01-18 |
| RU2015129577A (ru) | 2017-01-24 |
| CN109330980B (zh) | 2021-12-21 |
| DE202012012130U1 (de) | 2014-03-21 |
| JP2016505579A (ja) | 2016-02-25 |
| MY175753A (en) | 2020-07-08 |
| KR20150095698A (ko) | 2015-08-21 |
| US20160128939A9 (en) | 2016-05-12 |
| DK2934185T3 (en) | 2017-01-23 |
| JP6324989B2 (ja) | 2018-05-16 |
| ES2609504T3 (es) | 2017-04-20 |
| RS55490B1 (sr) | 2017-04-28 |
| US20150342881A1 (en) | 2015-12-03 |
| SI2934185T1 (sl) | 2017-02-28 |
| CY1118432T1 (el) | 2017-06-28 |
| CN109330980A (zh) | 2019-02-15 |
| CN104902765A (zh) | 2015-09-09 |
| PL2934185T3 (pl) | 2017-07-31 |
| BR112015014654B1 (pt) | 2020-08-18 |
| US11311483B2 (en) | 2022-04-26 |
| HK1211801A1 (en) | 2016-06-03 |
| KR20180007005A (ko) | 2018-01-19 |
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