BR102015012091A8 - método para a preparação de uma solução de albumina humana, e, composição - Google Patents
método para a preparação de uma solução de albumina humana, e, composiçãoInfo
- Publication number
- BR102015012091A8 BR102015012091A8 BR102015012091A BR102015012091A BR102015012091A8 BR 102015012091 A8 BR102015012091 A8 BR 102015012091A8 BR 102015012091 A BR102015012091 A BR 102015012091A BR 102015012091 A BR102015012091 A BR 102015012091A BR 102015012091 A8 BR102015012091 A8 BR 102015012091A8
- Authority
- BR
- Brazil
- Prior art keywords
- solution
- preparation
- composition
- human albumin
- albumin
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 102000008100 Human Serum Albumin Human genes 0.000 title abstract 4
- 108091006905 Human Serum Albumin Proteins 0.000 title abstract 4
- 102000009027 Albumins Human genes 0.000 abstract 2
- 108010088751 Albumins Proteins 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
método para a preparação de uma solução de albumina humana, composição, e, uso de uma composição. a presente invenção refere-se a um método para a preparação de uma solução de albumina humana, mais particularmente ela refere-se a um método compreendendo um estágio de redução do oxigênio dissolvido na dita solução de albumina até uma concentração igual a ou menor que 0,5 ppm. com o método da presente invenção é possível obter uma solução de albumina humana tendo um redox mais próximo do estado redox da albumina presente em plasma humano.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES201430824A ES2524516B1 (es) | 2014-05-29 | 2014-05-29 | Procedimiento de preparación de albúmina humana con nivel de oxígeno disuelto reducido |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR102015012091A2 BR102015012091A2 (pt) | 2016-01-05 |
| BR102015012091A8 true BR102015012091A8 (pt) | 2021-03-16 |
Family
ID=52003454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR102015012091A BR102015012091A8 (pt) | 2014-05-29 | 2015-05-26 | método para a preparação de uma solução de albumina humana, e, composição |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US10350274B2 (pt) |
| EP (1) | EP2952203B9 (pt) |
| JP (3) | JP2015224251A (pt) |
| KR (1) | KR101960729B1 (pt) |
| CN (1) | CN105315362B (pt) |
| AR (1) | AR100618A1 (pt) |
| AU (1) | AU2015202413B2 (pt) |
| BR (1) | BR102015012091A8 (pt) |
| CA (1) | CA2890642C (pt) |
| CL (1) | CL2015001446A1 (pt) |
| ES (2) | ES2524516B1 (pt) |
| HU (1) | HUE031823T2 (pt) |
| IL (1) | IL238898B (pt) |
| MX (1) | MX362869B (pt) |
| MY (1) | MY171771A (pt) |
| NZ (1) | NZ708537A (pt) |
| PL (1) | PL2952203T3 (pt) |
| PT (1) | PT2952203T (pt) |
| RU (1) | RU2657578C2 (pt) |
| SG (1) | SG10201504137PA (pt) |
| TW (1) | TWI607018B (pt) |
| ZA (1) | ZA201503539B (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2524516B1 (es) * | 2014-05-29 | 2015-03-31 | Grifols Worldwide Operations Limited | Procedimiento de preparación de albúmina humana con nivel de oxígeno disuelto reducido |
| WO2017189919A2 (en) | 2016-04-28 | 2017-11-02 | Alkahest, Inc. | Blood plasma and plasma fractions as therapy for tumor growth and progression |
| CN115957309A (zh) | 2016-08-18 | 2023-04-14 | 万能溶剂有限公司 | 作为衰老相关认知障碍的治疗的血浆级分 |
| AU2018257921B2 (en) | 2017-04-26 | 2024-06-06 | Alkahest, Inc. | Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products |
| WO2020018343A1 (en) | 2018-07-20 | 2020-01-23 | Alkahest, Inc. | Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products |
| CN109627322A (zh) * | 2019-01-07 | 2019-04-16 | 中国科学院过程工程研究所 | 一种从Cohn组分Ⅴ上清中分离纯化人血清白蛋白的方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4094965A (en) * | 1977-04-01 | 1978-06-13 | New England Nuclear Corporation | Diagnostic agents containing albumin and method for making same |
| SE9301581D0 (sv) * | 1993-05-07 | 1993-05-07 | Kabi Pharmacia Ab | Protein formulation |
| JPH07126182A (ja) * | 1993-10-27 | 1995-05-16 | Green Cross Corp:The | 組換えヒト血清アルブミン製剤の滅菌方法 |
| SE9402119D0 (sv) * | 1994-06-16 | 1994-06-16 | Pharmacia Ab | Solution |
| US5766582A (en) * | 1994-10-11 | 1998-06-16 | Schering Corporation | Stable, aqueous alfa interferon solution formulations |
| JP4254117B2 (ja) * | 2001-03-27 | 2009-04-15 | ニプロ株式会社 | アルブミン溶液収容プラスチック容器 |
| EP1245217B1 (en) * | 2001-03-27 | 2009-10-28 | Nipro Corporation | Plastic container containing albumin solution |
| WO2003002139A1 (fr) * | 2001-06-29 | 2003-01-09 | Asahi Kasei Kabushiki Kaisha | Procede permettant d'ameliorer la stabilite de la preparation de proteines |
| US7252799B2 (en) * | 2001-08-31 | 2007-08-07 | Clearant, Inc. | Methods for sterilizing preparations containing albumin |
| DE602004002834T2 (de) * | 2003-08-28 | 2007-06-06 | Nipro Corp., Osaka | Künstlicher Sauerstoffträger und Herstellungsverfahren dafür |
| SI1986612T1 (sl) * | 2006-02-07 | 2013-01-31 | Shire Human Genetic Therapies, Inc. | Stabilizirana spojina glukocerebrosidaze |
| ES2294976B1 (es) * | 2007-11-12 | 2008-12-16 | Grifols, S.A. | "procedimiento de obtencion de albumina humana de alta eficacia para su uso en terapia de detoxificacion". |
| JP5990880B2 (ja) * | 2011-08-31 | 2016-09-14 | 東レ株式会社 | 有用タンパク質組成物およびその製造方法 |
| CN102816230B (zh) * | 2012-08-27 | 2014-02-12 | 同路生物制药股份有限公司 | 人血白蛋白的制备方法 |
| ES2524516B1 (es) * | 2014-05-29 | 2015-03-31 | Grifols Worldwide Operations Limited | Procedimiento de preparación de albúmina humana con nivel de oxígeno disuelto reducido |
-
2014
- 2014-05-29 ES ES201430824A patent/ES2524516B1/es not_active Expired - Fee Related
-
2015
- 2015-04-01 EP EP15382164.0A patent/EP2952203B9/en active Active
- 2015-04-01 HU HUE15382164A patent/HUE031823T2/en unknown
- 2015-04-01 ES ES15382164.0T patent/ES2601137T3/es active Active
- 2015-04-01 PT PT153821640T patent/PT2952203T/pt unknown
- 2015-04-01 PL PL15382164T patent/PL2952203T3/pl unknown
- 2015-05-01 CA CA2890642A patent/CA2890642C/en active Active
- 2015-05-06 AU AU2015202413A patent/AU2015202413B2/en active Active
- 2015-05-15 MY MYPI2015701570A patent/MY171771A/en unknown
- 2015-05-18 RU RU2015118453A patent/RU2657578C2/ru active
- 2015-05-19 IL IL238898A patent/IL238898B/en active IP Right Grant
- 2015-05-20 ZA ZA2015/03539A patent/ZA201503539B/en unknown
- 2015-05-21 MX MX2015006407A patent/MX362869B/es active IP Right Grant
- 2015-05-22 CN CN201510264800.9A patent/CN105315362B/zh active Active
- 2015-05-26 BR BR102015012091A patent/BR102015012091A8/pt not_active IP Right Cessation
- 2015-05-26 TW TW104116876A patent/TWI607018B/zh not_active IP Right Cessation
- 2015-05-26 SG SG10201504137PA patent/SG10201504137PA/en unknown
- 2015-05-27 AR ARP150101653A patent/AR100618A1/es active IP Right Grant
- 2015-05-27 NZ NZ708537A patent/NZ708537A/en not_active IP Right Cessation
- 2015-05-28 JP JP2015108569A patent/JP2015224251A/ja active Pending
- 2015-05-28 US US14/724,649 patent/US10350274B2/en active Active
- 2015-05-28 CL CL2015001446A patent/CL2015001446A1/es unknown
- 2015-05-28 KR KR1020150074568A patent/KR101960729B1/ko active IP Right Grant
-
2018
- 2018-04-27 JP JP2018086673A patent/JP2018115210A/ja active Pending
-
2020
- 2020-04-20 JP JP2020074749A patent/JP2020111614A/ja active Pending
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| B03A | Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B03H | Publication of an application: rectification [chapter 3.8 patent gazette] |
Free format text: REFERENTE A RPI 2348 DE 05/01/2016, QUANTO AO ITEM (54) |
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| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2673 DE 29-03-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |