BR112015013332A2 - método e sistema para sintonizar um controlador de circuito fechado para um pâncreas artificial - Google Patents

método e sistema para sintonizar um controlador de circuito fechado para um pâncreas artificial

Info

Publication number
BR112015013332A2
BR112015013332A2 BR112015013332A BR112015013332A BR112015013332A2 BR 112015013332 A2 BR112015013332 A2 BR 112015013332A2 BR 112015013332 A BR112015013332 A BR 112015013332A BR 112015013332 A BR112015013332 A BR 112015013332A BR 112015013332 A2 BR112015013332 A2 BR 112015013332A2
Authority
BR
Brazil
Prior art keywords
controller
individual
insulin
glucose levels
tuning
Prior art date
Application number
BR112015013332A
Other languages
English (en)
Inventor
Finan Daniel
Venugopalan Ramakrishna
Mccann Thomas
Original Assignee
Animas Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Animas Corp filed Critical Animas Corp
Publication of BR112015013332A2 publication Critical patent/BR112015013332A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M2005/14288Infusion or injection simulation
    • A61M2005/14296Pharmacokinetic models
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/35Communication
    • A61M2205/3546Range
    • A61M2205/3553Range remote, e.g. between patient's home and doctor's office
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/35Communication
    • A61M2205/3546Range
    • A61M2205/3561Range local, e.g. within room or hospital
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/35Communication
    • A61M2205/3576Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
    • A61M2205/3592Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using telemetric means, e.g. radio or optical transmission
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/70General characteristics of the apparatus with testing or calibration facilities
    • A61M2205/702General characteristics of the apparatus with testing or calibration facilities automatically during use
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00Ancillary equipment
    • A61M2209/01Remote controllers for specific apparatus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/005Parameter used as control input for the apparatus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00Measuring parameters of the user
    • A61M2230/20Blood composition characteristics
    • A61M2230/201Glucose concentration

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Medical Informatics (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Pathology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • External Artificial Organs (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)

Abstract

resumo patente de invenção "método e sistema para sintonizar um controlador de circuito fechado para um pâncreas artificial". a presente invenção descreve e ilustrada um sistema de gerenciamento de diabetes que inclui uma bomba de infusão, um sensor de glicose e um controlador com um método programado no controlador. a bomba de infusão é configurada para fornecer insulina a um indivíduo. o sensor de glicose é configurado para monitorar os níveis de glicose no indivíduo e fornecer sinais de saída representativos dos níveis de glicose no indivíduo. o controlador é programado para receber sinais de pelo menos um dentre o sensor de glicose e a bomba e é configurado para emitir sinais à bomba para fornecer uma quantidade de insulina determinada por um controlador de retroinformações que utiliza um modelo de controle preditivo do indivíduo com base em níveis de glicose desejados, na quantidade de insulina aplicada e nos níveis de glicose medidos no indivíduo. o controlador é configurado também para fornecer insulina com o uso de um fator de ajuste baseado no módulo de índice de omissão ou em um módulo de índice de calibração.
BR112015013332A 2012-12-07 2013-12-05 método e sistema para sintonizar um controlador de circuito fechado para um pâncreas artificial BR112015013332A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/708,032 US9486578B2 (en) 2012-12-07 2012-12-07 Method and system for tuning a closed-loop controller for an artificial pancreas
PCT/US2013/073289 WO2014089282A1 (en) 2012-12-07 2013-12-05 Method and system for tuning a closed-loop controller for an artificial pancreas

Publications (1)

Publication Number Publication Date
BR112015013332A2 true BR112015013332A2 (pt) 2017-07-11

Family

ID=50881750

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015013332A BR112015013332A2 (pt) 2012-12-07 2013-12-05 método e sistema para sintonizar um controlador de circuito fechado para um pâncreas artificial

Country Status (12)

Country Link
US (1) US9486578B2 (pt)
EP (1) EP2928524A4 (pt)
JP (1) JP6312696B2 (pt)
KR (1) KR20150093213A (pt)
CN (1) CN104837517B (pt)
AU (1) AU2013355206B2 (pt)
BR (1) BR112015013332A2 (pt)
CA (1) CA2892785A1 (pt)
HK (1) HK1214983A1 (pt)
RU (1) RU2652059C2 (pt)
TW (1) TWI619481B (pt)
WO (1) WO2014089282A1 (pt)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8065161B2 (en) 2003-11-13 2011-11-22 Hospira, Inc. System for maintaining drug information and communicating with medication delivery devices
JP2010507176A (ja) 2006-10-16 2010-03-04 ホスピラ・インコーポレイテツド 複数のデバイス管理システムからの動態情報および構成情報を比較および利用するためのシステムおよび方法
US7751907B2 (en) 2007-05-24 2010-07-06 Smiths Medical Asd, Inc. Expert system for insulin pump therapy
US8221345B2 (en) 2007-05-30 2012-07-17 Smiths Medical Asd, Inc. Insulin pump based expert system
US7959598B2 (en) 2008-08-20 2011-06-14 Asante Solutions, Inc. Infusion pump systems and methods
US8271106B2 (en) 2009-04-17 2012-09-18 Hospira, Inc. System and method for configuring a rule set for medical event management and responses
US8882701B2 (en) 2009-12-04 2014-11-11 Smiths Medical Asd, Inc. Advanced step therapy delivery for an ambulatory infusion pump and system
AU2012325937B2 (en) 2011-10-21 2018-03-01 Icu Medical, Inc. Medical device update system
CN105050539B (zh) * 2013-01-14 2018-05-18 加利福尼亚大学董事会 用于1型糖尿病应用的人造胰腺的模型预测控制问题中的每日周期性目标区间调节
US9641432B2 (en) 2013-03-06 2017-05-02 Icu Medical, Inc. Medical device communication method
US10357606B2 (en) 2013-03-13 2019-07-23 Tandem Diabetes Care, Inc. System and method for integration of insulin pumps and continuous glucose monitoring
US9561324B2 (en) 2013-07-19 2017-02-07 Bigfoot Biomedical, Inc. Infusion pump system and method
WO2015031774A1 (en) 2013-08-30 2015-03-05 Hospira, Inc. System and method of monitoring and managing a remote infusion regimen
US9662436B2 (en) 2013-09-20 2017-05-30 Icu Medical, Inc. Fail-safe drug infusion therapy system
US9474855B2 (en) 2013-10-04 2016-10-25 Animas Corporation Method and system for controlling a tuning factor due to sensor replacement for closed-loop controller in an artificial pancreas
US10311972B2 (en) 2013-11-11 2019-06-04 Icu Medical, Inc. Medical device system performance index
AU2014353130B9 (en) 2013-11-19 2019-09-05 Icu Medical, Inc. Infusion pump automation system and method
US10569015B2 (en) 2013-12-02 2020-02-25 Bigfoot Biomedical, Inc. Infusion pump system and method
WO2015168427A1 (en) 2014-04-30 2015-11-05 Hospira, Inc. Patient care system with conditional alarm forwarding
CN104027867A (zh) * 2014-06-13 2014-09-10 杨力 便携式智能双功糖尿病治疗泵
US9724470B2 (en) 2014-06-16 2017-08-08 Icu Medical, Inc. System for monitoring and delivering medication to a patient and method of using the same to minimize the risks associated with automated therapy
US9539383B2 (en) 2014-09-15 2017-01-10 Hospira, Inc. System and method that matches delayed infusion auto-programs with manually entered infusion programs and analyzes differences therein
CN104667379B (zh) * 2015-03-06 2017-08-15 上海交通大学 动态闭环控制的胰岛素泵
US9878097B2 (en) 2015-04-29 2018-01-30 Bigfoot Biomedical, Inc. Operating an infusion pump system
US20160339175A1 (en) * 2015-05-20 2016-11-24 Medtronic Minimed, Inc. Infusion devices and related methods for therapy recommendations
EP3304370B1 (en) 2015-05-26 2020-12-30 ICU Medical, Inc. Infusion pump system and method with multiple drug library editor source capability
EP3314548B1 (en) * 2015-06-28 2021-10-06 The Regents of The University of California Velocity-weighting model predictive control of an artificial pancreas for type 1 diabetes applications
WO2017027459A1 (en) 2015-08-07 2017-02-16 Trustees Of Boston University Glucose control system with automatic adaptation of glucose target
CN108352182A (zh) * 2015-11-12 2018-07-31 阿文特公司 患者结果跟踪平台
US10569016B2 (en) 2015-12-29 2020-02-25 Tandem Diabetes Care, Inc. System and method for switching between closed loop and open loop control of an ambulatory infusion pump
US10449294B1 (en) 2016-01-05 2019-10-22 Bigfoot Biomedical, Inc. Operating an infusion pump system
US10987468B2 (en) 2016-01-05 2021-04-27 Bigfoot Biomedical, Inc. Operating multi-modal medicine delivery systems
AU2017207484B2 (en) * 2016-01-14 2021-05-13 Bigfoot Biomedical, Inc. Adjusting insulin delivery rates
US10332632B2 (en) * 2016-06-01 2019-06-25 Roche Diabetes Care, Inc. Control-to-range failsafes
WO2018013842A1 (en) 2016-07-14 2018-01-18 Icu Medical, Inc. Multi-communication path selection and security system for a medical device
CN108261591B (zh) * 2016-12-30 2021-10-08 上海移宇科技股份有限公司 一种人工胰腺的闭环控制算法
US10583250B2 (en) 2017-01-13 2020-03-10 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
US10500334B2 (en) 2017-01-13 2019-12-10 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
US10610644B2 (en) 2017-01-13 2020-04-07 Bigfoot Biomedical, Inc. Insulin delivery methods, systems and devices
US10881793B2 (en) 2017-01-13 2021-01-05 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
US10758675B2 (en) 2017-01-13 2020-09-01 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
US11033682B2 (en) 2017-01-13 2021-06-15 Bigfoot Biomedical, Inc. Insulin delivery methods, systems and devices
USD853583S1 (en) 2017-03-29 2019-07-09 Becton, Dickinson And Company Hand-held device housing
US10729849B2 (en) * 2017-04-07 2020-08-04 LifeSpan IP Holdings, LLC Insulin-on-board accounting in an artificial pancreas system
EP3618713B1 (en) * 2017-05-05 2021-12-15 Eli Lilly and Company Closed loop control of physiological glucose
EP3438858A1 (en) 2017-08-02 2019-02-06 Diabeloop Closed-loop blood glucose control systems and methods
WO2019125932A1 (en) 2017-12-21 2019-06-27 Eli Lilly And Company Closed loop control of physiological glucose
US11139058B2 (en) 2018-07-17 2021-10-05 Icu Medical, Inc. Reducing file transfer between cloud environment and infusion pumps
EP4297379A3 (en) 2018-07-17 2024-01-10 ICU Medical, Inc. Systems and methods for facilitating clinical messaging in a network environment
WO2020018388A1 (en) 2018-07-17 2020-01-23 Icu Medical, Inc. Updating infusion pump drug libraries and operational software in a networked environment
US11152108B2 (en) 2018-07-17 2021-10-19 Icu Medical, Inc. Passing authentication token to authorize access to rest calls via web sockets
AU2019309766B2 (en) 2018-07-26 2024-06-13 Icu Medical, Inc. Drug library management system
US10692595B2 (en) 2018-07-26 2020-06-23 Icu Medical, Inc. Drug library dynamic version management
US11957876B2 (en) 2019-07-16 2024-04-16 Beta Bionics, Inc. Glucose control system with automated backup therapy protocol generation
JP2022541491A (ja) 2019-07-16 2022-09-26 ベータ バイオニクス,インコーポレイテッド 血糖制御システム
DE112020003406T5 (de) 2019-07-16 2022-06-23 Beta Bionics, Inc. Blutzuckerkontrollsystem
US11883208B2 (en) * 2019-08-06 2024-01-30 Medtronic Minimed, Inc. Machine learning-based system for estimating glucose values based on blood glucose measurements and contextual activity data
WO2021026399A1 (en) * 2019-08-06 2021-02-11 Medtronic Minimed, Inc. Machine learning-based system for estimating glucose values
US20220039755A1 (en) 2020-08-06 2022-02-10 Medtronic Minimed, Inc. Machine learning-based system for estimating glucose values
US20230051295A1 (en) * 2020-01-21 2023-02-16 Medtrum Technologies Inc. Medical device with safety verification and safety verification method thereof
US11324889B2 (en) * 2020-02-14 2022-05-10 Insulet Corporation Compensation for missing readings from a glucose monitor in an automated insulin delivery system
CN112402731B (zh) * 2020-10-10 2023-05-26 广东食品药品职业学院 一种预防低血糖现象的闭环胰岛素输注系统
JP2023551633A (ja) * 2020-10-14 2023-12-12 ユニバーシティ オブ バージニア パテント ファンデーション 報知されない血糖揺らぎの原因後の血糖反応を改善する閉ループ制御の方法及びシステム
WO2023070250A1 (en) * 2021-10-25 2023-05-04 Medtrum Technologies Inc. Closed-loop artificial pancreas insulin infusion personalized control system

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4055175A (en) 1976-05-07 1977-10-25 Miles Laboratories, Inc. Blood glucose control apparatus
US4280494A (en) 1979-06-26 1981-07-28 Cosgrove Robert J Jun System for automatic feedback-controlled administration of drugs
US5298022A (en) 1989-05-29 1994-03-29 Amplifon Spa Wearable artificial pancreas
WO1992014197A1 (en) 1991-02-08 1992-08-20 Kabushiki Kaisha Toshiba Model forecasting controller
US5283729A (en) 1991-08-30 1994-02-01 Fisher-Rosemount Systems, Inc. Tuning arrangement for turning the control parameters of a controller
US7806886B2 (en) * 1999-06-03 2010-10-05 Medtronic Minimed, Inc. Apparatus and method for controlling insulin infusion with state variable feedback
JP3647032B2 (ja) 2000-08-18 2005-05-11 シグナス, インコーポレイテッド 低血糖事象の予測のためのマイクロプロセッサーおよびデバイス
EP1575656B1 (en) 2002-10-11 2009-06-17 Becton, Dickinson and Company Insulin delivery system with sensor
US8060173B2 (en) 2003-08-01 2011-11-15 Dexcom, Inc. System and methods for processing analyte sensor data
US7591801B2 (en) * 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US7451004B2 (en) 2005-09-30 2008-11-11 Fisher-Rosemount Systems, Inc. On-line adaptive model predictive control in a process control system
RU2447905C2 (ru) * 2006-02-09 2012-04-20 Дека Продактс Лимитед Партнершип Насосные системы доставки текучих сред и способы применения устройства приложения усилия
US7577483B2 (en) 2006-05-25 2009-08-18 Honeywell Asca Inc. Automatic tuning method for multivariable model predictive controllers
US8585593B2 (en) 2006-11-27 2013-11-19 University Of Virginia Patent Foundation Method, system, and computer program product for the detection of physical activity by changes in heart rate, assessment of fast changing metabolic states, and applications of closed and open control loop in diabetes
US10154804B2 (en) * 2007-01-31 2018-12-18 Medtronic Minimed, Inc. Model predictive method and system for controlling and supervising insulin infusion
US8930203B2 (en) * 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8600681B2 (en) 2007-05-14 2013-12-03 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
EP2203112B1 (en) 2007-06-21 2020-03-11 University Of Virginia Patent Foundation Method, system and computer simulation environment for testing of monitoring and control strategies in diabetes
US9839395B2 (en) 2007-12-17 2017-12-12 Dexcom, Inc. Systems and methods for processing sensor data
TWI394580B (zh) * 2008-04-28 2013-05-01 Halozyme Inc 超快起作用胰島素組成物
US8046089B2 (en) 2008-06-20 2011-10-25 Honeywell International Inc. Apparatus and method for model predictive control (MPC) of a nonlinear process
EP2369980B1 (en) 2008-11-26 2020-02-26 University Of Virginia Patent Foundation METHOD and SYSTEM FOR TRACKING OF BLOOD GLUCOSE VARIABILITY IN DIABETES
GB2466183A (en) 2008-12-09 2010-06-16 Cambridge Entpr Ltd Closed loop diabetes management system
WO2010099313A1 (en) 2009-02-25 2010-09-02 University Of Virginia Patent Foundation Cgm-based prevention of hypoglycemia via hypoglycemia risk assessment and smooth reduction insulin delivery
DK2400882T3 (en) * 2009-02-26 2017-09-18 Dreamed Diabetes Ltd METHOD AND SYSTEM FOR AUTOMATIC MONITORING OF DIABETES-RELATED TREATMENTS
CN102576375B (zh) 2009-05-29 2016-05-18 弗吉尼亚大学专利基金会 用于糖尿病的开环和闭环控制的系统协调器和模块化体系结构
WO2010151834A1 (en) 2009-06-26 2010-12-29 University Of Virginia Patent Foundation System, method and computer simulation environment for in silico trials in prediabetes and type 2 diabetes
US20110196213A1 (en) 2009-06-26 2011-08-11 Roche Diagnostics Operations, Inc. Display For Biological Values
US20120245556A1 (en) 2009-09-01 2012-09-27 University Of Virginia Patent Foundation System, Method and Computer Program Product For Adjustment of Insulin Delivery in Diabetes Using Nominal Open-Loop Profiles
EP2473845A4 (en) 2009-09-02 2014-04-30 Univ Virginia Patent Found PERSECUTION OF THE PROBABILITY OF THREATENING HYPOGLYCEMIA IN DIABETES THROUGH BLOOD SUGAR SELF-MONITORING DATA
US8762070B2 (en) 2010-02-11 2014-06-24 Regents Of The University Of California Systems, devices and methods to deliver biological factors or drugs to a subject
US20110313680A1 (en) 2010-06-22 2011-12-22 Doyle Iii Francis J Health Monitoring System
WO2012051344A2 (en) * 2010-10-12 2012-04-19 Regents Of The University Of California, The Maintaining multiple defined physiological zones using model predictive control
US8657746B2 (en) 2010-10-28 2014-02-25 Medtronic Minimed, Inc. Glucose sensor signal purity analysis
US8766803B2 (en) 2011-05-13 2014-07-01 Roche Diagnostics Operations, Inc. Dynamic data collection

Also Published As

Publication number Publication date
EP2928524A4 (en) 2016-04-27
WO2014089282A1 (en) 2014-06-12
CA2892785A1 (en) 2014-06-12
CN104837517B (zh) 2018-11-06
HK1214983A1 (zh) 2016-08-12
JP2016502869A (ja) 2016-02-01
AU2013355206A1 (en) 2015-07-16
US9486578B2 (en) 2016-11-08
TW201446227A (zh) 2014-12-16
CN104837517A (zh) 2015-08-12
KR20150093213A (ko) 2015-08-17
AU2013355206B2 (en) 2018-04-26
EP2928524A1 (en) 2015-10-14
RU2652059C2 (ru) 2018-04-24
JP6312696B2 (ja) 2018-04-18
US20140163517A1 (en) 2014-06-12
RU2015127092A (ru) 2017-01-12
TWI619481B (zh) 2018-04-01

Similar Documents

Publication Publication Date Title
BR112015013332A2 (pt) método e sistema para sintonizar um controlador de circuito fechado para um pâncreas artificial
BR112014032912A2 (pt) método e sistema para administrar bolus manuais ou eventos de refeição em controladores de circuito fechado
BR112016007230A2 (pt) método e sistema para controlar um fator de ajuste devido à substituição de sensor por controlador de circuito fechado em um pâncreas artificial
BR112015014941A2 (pt) método e sistema para um controle previsivo de modelo controle-para-alvo híbrido e controle-para-faixa de um pâncreas artificial
WO2008043724A3 (en) Regulated drug delivery system
BR112018015253A2 (pt) métodos e dispositivos para controlar dispositivos de vaporação eletrônicos
BRPI0817925B8 (pt) sistema para monitorar e regular níveis de glicose no sangue em uma corrente sanguínea
BR112014006505A2 (pt) disposição configurada e método para controlar um parâmetro ambiental em um espaço predial e sistema de controle para uma edificação
WO2017156482A8 (en) System and method for a tissue resection margin measurement device
BR112015016747A2 (pt) método e dispositivo de controle de uma velocidade de rotação de um acionador, e método e dispositivo para compensação de falhas na detecção de uma velocidade de rotação de um eixo
BR112018071163A8 (pt) Sistemas e dispositivos para rastreamento de movimento, avaliação e monitoramento e seus métodos de uso
WO2017209903A8 (en) Control-to-range failsafes
WO2011011739A3 (en) Real time management of data relating to physiological control of glucose levels
BR112013021042A2 (pt) ferramenta com sistema de navegação e guiamento integrado e aparelhos e métodos relacionados
BR112015018835A2 (pt) dispositivo de injeção
HK1146118A1 (en) Blood glucose level measuring system
BR112015001038A2 (pt) método e sistema para indicar hiperglicemia ou hipoglicemia para pessoas com diabetes
BR112013015377A2 (pt) dispositivo de terapia de luz
BR112018011002A2 (pt) variantes de fgf21
BR112018010382A2 (pt) sistema de navegação, rastreamento e guia para o posicionamento de instrumentos operacionais dentro do corpo de um paciente
BR112014001082A2 (pt) sistema de detecção, sensor e dispositivo de tratamento de animal que produz leite compreendendo os mesmos
BR112015028699A2 (pt) sistema e método para uma lente oftálmica controlada por processador
PH12016500213A1 (en) Beta-casein a2 and blood glucose levels
WO2008092828A3 (de) Spektrales messsystem zur ermittlung von substanzeigenschaften unter verwendung von terahertz-strahlung
BR112017012595A8 (pt) Sistema e método de gestão de uma lente ativa, óculos e lente ativa

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements