BR112014017624B8 - método para agitar uma solução contendo uma substância teste e método para analisar uma substância teste - Google Patents
método para agitar uma solução contendo uma substância teste e método para analisar uma substância teste Download PDFInfo
- Publication number
- BR112014017624B8 BR112014017624B8 BR112014017624A BR112014017624A BR112014017624B8 BR 112014017624 B8 BR112014017624 B8 BR 112014017624B8 BR 112014017624 A BR112014017624 A BR 112014017624A BR 112014017624 A BR112014017624 A BR 112014017624A BR 112014017624 B8 BR112014017624 B8 BR 112014017624B8
- Authority
- BR
- Brazil
- Prior art keywords
- test substance
- stirring
- solution containing
- analyzing
- substance
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F29/00—Mixers with rotating receptacles
- B01F29/15—Use of centrifuges for mixing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00158—Elements containing microarrays, i.e. "biochip"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00495—Centrifuges
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
método para agitar uma solução contendo uma substância teste e método para analisar uma substância teste a presente invenção descreve um meio para acelerar a reação de ligação seletiva entre uma substância de ligação seletiva imobilizada sobre um chip de análise e uma substância teste, em particular, um meio para possibilitar a análise de uma substância teste em um curto espaço de tempo. ainda, a presente invenção refere-se a um método de agitação de uma solução da substância teste compreendendo: a injeção de uma solução contendo a substância a um espaço em uma reentrância de um chip de análise, de tal modo que o espaço é parcialmente deixado sem preenchimento; e o chip de análise é rotacionado aplicando-se uma aceleração centrífuga não inferior a 1× g.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012043704 | 2012-02-29 | ||
| PCT/JP2013/055117 WO2013129469A1 (ja) | 2012-02-29 | 2013-02-27 | 溶液の攪拌方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR112014017624A2 BR112014017624A2 (pt) | 2017-06-27 |
| BR112014017624B1 BR112014017624B1 (pt) | 2020-04-14 |
| BR112014017624B8 true BR112014017624B8 (pt) | 2020-05-05 |
Family
ID=49082663
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014017624A BR112014017624B8 (pt) | 2012-02-29 | 2013-02-27 | método para agitar uma solução contendo uma substância teste e método para analisar uma substância teste |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9944976B2 (pt) |
| EP (1) | EP2821794B1 (pt) |
| JP (1) | JP6187259B2 (pt) |
| KR (1) | KR102039369B1 (pt) |
| CN (1) | CN104169722B (pt) |
| BR (1) | BR112014017624B8 (pt) |
| CA (1) | CA2861288C (pt) |
| DK (1) | DK2821794T3 (pt) |
| ES (1) | ES2623098T3 (pt) |
| PL (1) | PL2821794T3 (pt) |
| WO (1) | WO2013129469A1 (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10712660B2 (en) * | 2016-12-21 | 2020-07-14 | Canon Kabushiki Kaisha | Template for imprint lithography including a recession and an apparatus and method of using the template |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6309875B1 (en) | 2000-02-29 | 2001-10-30 | Agilent Technologies, Inc. | Apparatus for biomolecular array hybridization facilitated by agitation during centrifuging |
| EP1302244A1 (en) * | 2001-10-15 | 2003-04-16 | Agilent Technologies, Inc. (a Delaware corporation) | Chemical analysis using array hybridization |
| JP3557419B2 (ja) | 2002-05-24 | 2004-08-25 | 株式会社日立製作所 | ハイブリダイゼーション方法および装置 |
| JP4473007B2 (ja) | 2004-02-20 | 2010-06-02 | 三菱レイヨン株式会社 | ハイブリダイゼーション方法 |
| KR101148860B1 (ko) | 2004-03-23 | 2012-05-29 | 도레이 카부시키가이샤 | 용액을 교반하는 방법 |
| JP4857882B2 (ja) | 2006-04-14 | 2012-01-18 | 東レ株式会社 | 検体溶液の撹拌方法 |
| CN104297467A (zh) * | 2007-01-24 | 2015-01-21 | 东丽株式会社 | 分析用芯片及分析方法 |
| SE0700424L (sv) | 2007-02-21 | 2008-05-20 | Gyros Patent Ab | Förfarande för blandning av alikvoter i en mikrokanalstruktur |
| US20120046187A1 (en) * | 2009-03-16 | 2012-02-23 | Toray Industries, Inc. | Analysis chip, analysis method and method for stirring solution |
| EP2309266A1 (en) * | 2009-09-21 | 2011-04-13 | F. Hoffmann-La Roche AG | Method for carrying out reactions in an analytical device |
-
2013
- 2013-02-27 PL PL13755655T patent/PL2821794T3/pl unknown
- 2013-02-27 DK DK13755655.1T patent/DK2821794T3/en active
- 2013-02-27 CN CN201380011640.6A patent/CN104169722B/zh active Active
- 2013-02-27 CA CA2861288A patent/CA2861288C/en active Active
- 2013-02-27 BR BR112014017624A patent/BR112014017624B8/pt not_active IP Right Cessation
- 2013-02-27 WO PCT/JP2013/055117 patent/WO2013129469A1/ja active Application Filing
- 2013-02-27 ES ES13755655.1T patent/ES2623098T3/es active Active
- 2013-02-27 KR KR1020147018545A patent/KR102039369B1/ko active IP Right Grant
- 2013-02-27 US US14/381,715 patent/US9944976B2/en active Active
- 2013-02-27 JP JP2013513887A patent/JP6187259B2/ja active Active
- 2013-02-27 EP EP13755655.1A patent/EP2821794B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| KR20140138112A (ko) | 2014-12-03 |
| CA2861288C (en) | 2019-10-01 |
| PL2821794T3 (pl) | 2017-08-31 |
| KR102039369B1 (ko) | 2019-11-01 |
| CA2861288A1 (en) | 2013-09-06 |
| EP2821794A1 (en) | 2015-01-07 |
| US20150045250A1 (en) | 2015-02-12 |
| JPWO2013129469A1 (ja) | 2015-07-30 |
| ES2623098T3 (es) | 2017-07-10 |
| WO2013129469A1 (ja) | 2013-09-06 |
| JP6187259B2 (ja) | 2017-08-30 |
| CN104169722B (zh) | 2017-03-08 |
| US9944976B2 (en) | 2018-04-17 |
| EP2821794B1 (en) | 2017-04-05 |
| DK2821794T3 (en) | 2017-06-06 |
| BR112014017624A2 (pt) | 2017-06-27 |
| BR112014017624B1 (pt) | 2020-04-14 |
| CN104169722A (zh) | 2014-11-26 |
| EP2821794A4 (en) | 2015-12-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112015022141A2 (pt) | Método de quantificação de eficiência de capeamento de mrna, kit e método de fabricação de mrna | |
| HK1217971A1 (zh) | 用於核酸分析的方法、組合物和試劑盒 | |
| BR112016024072A2 (pt) | métodos, kits e aparelho para ampliar uma população de células | |
| BR112014010955A2 (pt) | sistema e método para processar amostras | |
| BR112014022638A8 (pt) | Método, suporte físico e equipamento para transformar especificadores de instrução de um ambiente computacional | |
| BR112015008723A2 (pt) | aparelho para liberar agente químico em um furo de poço, método para fornecer um agente químico e método | |
| WO2012094227A3 (en) | Systems and methods for sample analysis | |
| BR112013003398A2 (pt) | método e aparelho para recipiente de teste de vazamento | |
| EP2756822A3 (en) | Instrumentation for positioning and securing a graft | |
| BR112015002287A2 (pt) | processo para obtenção e detecção de um marcador de objetos a serem identificados, o marcador, método para autenticação e método para verificação | |
| MX2015013310A (es) | Metodo y reactivo para determinar metabolitos de la vitamina d. | |
| EP2600154A4 (en) | METHOD FOR PRODUCING DATA SET FOR INTEGRATED PROTEOMIC, INTEGRATED PROTEASE METHOD USING THE DATA SET FOR INTEGRATED PROTEOME, THAT IS PRODUCED BY THE PRODUCTION METHOD, AND METHOD FOR IDENTIFYING, BY ITS USE, THE SUBSTANCE THAT IN THE ORIGIN | |
| BR112012020404A2 (pt) | epimerização de sacarídeos. | |
| EP2952866A4 (en) | METHOD FOR EVALUATING RESIDUAL SOLICITATION USING INSTRUMENTATED PENETRATION HARDNESS TESTING TECHNIQUE, STORAGE MEDIUM MEMORY COMPRISING COMPUTER PROGRAMMING, AND PENETRATION HARDNESS TEST APPARATUS FOR REALIZING HARDNESS TESTING BY INSTRUMENTED PENETRATION BY OPERATING THE STORAGE MEDIUM | |
| BR102013018764B8 (pt) | Toner e agente de revelação | |
| BR112016002573A2 (pt) | método para a preparação de produtos à base de carne de músculo inteiro contendo óleo e produtos à base de carne reconstituída | |
| BR112017003167A2 (pt) | método in vitro e aparelho para análise do comportamento de substâncias em ambiente fisiológico simulado | |
| BR112016021322B8 (pt) | Método para a produção de materiais microporosos com troca de metais por troca de íons no estado sólido e método para a remoção de óxidos de nitrogênio do gás de exaustão pela redução catalítica seletiva com um redutor | |
| BR112012014621A2 (pt) | processo para a preparação de compostos de quelato | |
| BR112018000464A2 (pt) | sistema de armazenamento gasoso, métodos para produzir e utilizá-lo | |
| BR102013016476A8 (pt) | Aparelho e método de teste de amostra | |
| BR112016026874A8 (pt) | dispositivo de estação base, equipamento de usuário, método para receber informações de estado de canal e produto de programa de computador | |
| WO2013130537A3 (en) | Field-enhanced thermal decomposition of fuel storage compositions | |
| BR112014032916A2 (pt) | anticorpos anti-fármacos e usos destes para o monitoramento de fármaco | |
| MX337767B (es) | Tecnologia de simulacion integrada. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B09X | Republication of the decision to grant [chapter 9.1.3 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/02/2013, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: REF. RPI 2571 QUANTO AO ENDERECO. |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 9A ANUIDADE. |
|
| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2659 DE 21-12-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |