BR112014015804A2 - Método para produzir uma composição de matéria e aparelhos - Google Patents

Método para produzir uma composição de matéria e aparelhos Download PDF

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Publication number
BR112014015804A2
BR112014015804A2 BR112014015804A BR112014015804A BR112014015804A2 BR 112014015804 A2 BR112014015804 A2 BR 112014015804A2 BR 112014015804 A BR112014015804 A BR 112014015804A BR 112014015804 A BR112014015804 A BR 112014015804A BR 112014015804 A2 BR112014015804 A2 BR 112014015804A2
Authority
BR
Brazil
Prior art keywords
quot
producing
matter
composition
shaped tool
Prior art date
Application number
BR112014015804A
Other languages
English (en)
Other versions
BR112014015804B1 (pt
Inventor
Barry Smith
Lawrence Gazda
Melissa Laramore
Timothy Hamilton
Original Assignee
The Rogosin Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Rogosin Inst Inc filed Critical The Rogosin Inst Inc
Publication of BR112014015804A2 publication Critical patent/BR112014015804A2/pt
Publication of BR112014015804B1 publication Critical patent/BR112014015804B1/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012—Cell encapsulation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B25—HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
    • B25J—MANIPULATORS; CHAMBERS PROVIDED WITH MANIPULATION DEVICES
    • B25J15/00—Gripping heads and other end effectors
    • B25J15/06—Gripping heads and other end effectors with vacuum or magnetic holding means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B25—HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
    • B25J—MANIPULATORS; CHAMBERS PROVIDED WITH MANIPULATION DEVICES
    • B25J15/00—Gripping heads and other end effectors
    • B25J15/06—Gripping heads and other end effectors with vacuum or magnetic holding means
    • B25J15/0616—Gripping heads and other end effectors with vacuum or magnetic holding means with vacuum
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/70—Polysaccharides
    • C12N2533/76—Agarose, agar-agar

Abstract

método para produzir uma composição de matéria e aparelhos. a invenção refere-se a um método aperfeiçoado para produzir grânulos (beads) de agarose revestidos por agarose que contêm células. o método que é, de preferência, automatizado envolve colocar grânulos produzidos em uma amostra de óleo mineral a um gradiente de temperatura, de tal modo que a temperatura caia à medida que o grânulo se move através do óleo. de preferência, uma ?ferramenta em forma de trompete? e uma ?ferramenta em forma de canudo? são empregadas no método.
BR112014015804-5A 2012-01-31 2013-01-30 Método para produzir uma composição de matéria BR112014015804B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261592949P 2012-01-31 2012-01-31
US61/592,949 2012-01-31
PCT/US2013/023802 WO2013116306A1 (en) 2012-01-31 2013-01-30 Improved method for manufacture of macrobeads

Publications (2)

Publication Number Publication Date
BR112014015804A2 true BR112014015804A2 (pt) 2021-08-31
BR112014015804B1 BR112014015804B1 (pt) 2022-10-18

Family

ID=48903127

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014015804-5A BR112014015804B1 (pt) 2012-01-31 2013-01-30 Método para produzir uma composição de matéria

Country Status (21)

Country Link
US (2) US9090866B2 (pt)
EP (1) EP2809782B1 (pt)
JP (1) JP5986226B2 (pt)
KR (1) KR101722824B1 (pt)
CN (1) CN103975059B (pt)
AP (1) AP2014007623A0 (pt)
AU (1) AU2013202026B2 (pt)
BR (1) BR112014015804B1 (pt)
CA (1) CA2851023C (pt)
DK (1) DK2809782T3 (pt)
ES (1) ES2647613T3 (pt)
HK (1) HK1199903A1 (pt)
HU (1) HUE034618T2 (pt)
IL (1) IL231834A (pt)
MX (1) MX350593B (pt)
NO (1) NO2904201T3 (pt)
NZ (1) NZ624195A (pt)
PL (1) PL2809782T3 (pt)
PT (1) PT2809782T (pt)
RU (1) RU2591518C2 (pt)
WO (1) WO2013116306A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017020141A1 (es) * 2015-08-03 2017-02-09 Vera Campos Claudio Herramienta, sistema y procedimiento automatizado de toma de muestras
CN109642213B (zh) * 2016-03-01 2023-02-24 牛津大学创新有限公司 载有装载的支架的相转移
DE102017106867B4 (de) * 2017-03-30 2021-12-02 Hamilton Bonaduz Ag Verfahren zur Herstellung einer Portionseinheit
TWI787697B (zh) * 2019-12-30 2022-12-21 財團法人工業技術研究院 外泌體的分離方法、膠體粒子及其製備方法
TW202208062A (zh) * 2020-08-20 2022-03-01 財桂生物股份有限公司 微量管上蓋及其組裝裝置

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1418228E (pt) * 1994-01-13 2006-09-29 Rogosin Inst Processo de preparacao de uma biblioteca multicombinatoria de vectores de expressao de genes de anticorpos.
US5888497A (en) 1996-04-03 1999-03-30 The Rogosin Institute Agarose coated agarose beads containing cancer cells that produce material which suppresses cancer cell proliferation
US6303151B1 (en) 1996-04-03 2001-10-16 The Rogosin Institute Cancer-cell proliferation-suppressing material produced by cancer cells restricted by entrapment
US6224912B1 (en) 1996-04-03 2001-05-01 The Rogo Institute Cancer-cell proliferation-suppressing material produced by cancer cells restricted by entrapment
DE69725317T2 (de) * 1996-04-03 2004-07-29 The Rogosin Institute Implantierbare agarose-kollagenkügelchen enthaltende zellen, die ein diffusionsfähiges biologisches produkt bilden und ihre verwendung
US20030012699A1 (en) * 1998-11-18 2003-01-16 Thomas Moore Simultaneous handling of magnetic beads in a two-dimensional arrangement
US6497155B1 (en) 1999-02-09 2002-12-24 Pharmacopeia, Inc. Article comprising a particle retrieval device
US6558665B1 (en) 1999-05-18 2003-05-06 Arch Development Corporation Encapsulating particles with coatings that conform to size and shape of the particles
JP2001168127A (ja) * 1999-12-08 2001-06-22 Japan Em Kk 微小球体移載装置
US20050053586A1 (en) 2003-09-04 2005-03-10 Bryan Conn Entrapped stem cells and uses thereof
JP2005114576A (ja) 2003-10-08 2005-04-28 Hitachi Software Eng Co Ltd 両親媒性分子固定化ビーズ、その製造方法、及びキャピラリビーズアレイのビーズ配列方法
WO2005082214A1 (en) 2004-02-25 2005-09-09 Andhow Innovations, Llc. Leak resistant siphoning device for use in fluid transfer
JP4520359B2 (ja) 2005-05-13 2010-08-04 日立ソフトウエアエンジニアリング株式会社 粒子捕捉装置、並びに粒子配列方法及び粒子配列装置
SG131015A1 (en) 2005-09-15 2007-04-26 Millipore Corp Method and apparatus for making porous agarose beads
CA2622529C (en) * 2005-09-26 2014-02-18 Lawrence Gazda Secretory cell-containing macrobeads comprising seakem gold agarose, and uses thereof
CN102316988B (zh) 2007-09-29 2014-02-19 Ei频谱有限责任公司 仪表化移液器吸头
WO2010138702A1 (en) * 2009-05-28 2010-12-02 Corning Incorporated Swellable synthetic microcarriers for culturing cells
USD625429S1 (en) 2009-10-01 2010-10-12 Holger Link Pipette
DE102010040687A1 (de) 2010-09-14 2012-03-15 Hamilton Bonaduz Ag Verfahren zum Herstellen von Wirkstoff-Beads
DE102010040681A1 (de) 2010-09-14 2012-03-15 Hamilton Bonaduz Ag Unterdruckgreifer zur Handhabung von Wirkstoff-Beads mit vorzugsweise konkaver Bead-Kontaktfläche
DE102010040685A1 (de) 2010-09-14 2012-03-15 Hamilton Bonaduz Ag Temperiervorrichtung zur thermischen Verfestigung von Wirkstoff-Beads
DE102010040684A1 (de) 2010-09-14 2012-03-15 Hamilton Bonaduz Ag Röhrenförmiger Unterdruckgreifer zur Handhabung von Rohlingen von Wirkstoff-Beads
DE102011050024A1 (de) 2011-04-29 2012-10-31 Hamilton Bonaduz Ag Analysevorrichtung für eine berührungslose Analyse der Ausformung eines transparenten Körpers und Verfahren zur Durchführung der berührungslosen Analyse

Also Published As

Publication number Publication date
KR20140122742A (ko) 2014-10-20
CA2851023A1 (en) 2013-08-08
EP2809782A4 (en) 2015-11-04
ES2647613T3 (es) 2017-12-22
BR112014015804B1 (pt) 2022-10-18
RU2591518C2 (ru) 2016-07-20
RU2014133367A (ru) 2016-03-27
AU2013202026A1 (en) 2013-08-15
JP2015510396A (ja) 2015-04-09
CN103975059B (zh) 2016-08-31
WO2013116306A1 (en) 2013-08-08
PL2809782T3 (pl) 2018-04-30
DK2809782T3 (da) 2017-11-20
CA2851023C (en) 2018-03-20
EP2809782B1 (en) 2017-08-23
IL231834A (en) 2016-04-21
US20130202802A1 (en) 2013-08-08
MX350593B (es) 2017-09-11
EP2809782A1 (en) 2014-12-10
KR101722824B1 (ko) 2017-04-03
USRE47439E1 (en) 2019-06-18
NO2904201T3 (pt) 2018-01-20
HK1199903A1 (en) 2015-07-24
HUE034618T2 (en) 2018-02-28
MX2014009295A (es) 2014-09-11
AU2013202026B2 (en) 2014-05-08
CN103975059A (zh) 2014-08-06
US9090866B2 (en) 2015-07-28
JP5986226B2 (ja) 2016-09-06
NZ624195A (en) 2015-07-31
IL231834A0 (en) 2014-05-28
AP2014007623A0 (en) 2014-05-31
PT2809782T (pt) 2017-12-01

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Legal Events

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/01/2013, OBSERVADAS AS CONDICOES LEGAIS

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 11A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2759 DE 21-11-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.