BR112014010161B1 - Anticorpo anti-proteína tar de ligação ao dna que possui 43 kda (tdp-43), seu método de preparação e seu uso, composições, polinucleotídeos, vetor, e kit útil no diagnóstico ou monitoramento da progressão de uma proteinopatia de tdp-43 - Google Patents

Anticorpo anti-proteína tar de ligação ao dna que possui 43 kda (tdp-43), seu método de preparação e seu uso, composições, polinucleotídeos, vetor, e kit útil no diagnóstico ou monitoramento da progressão de uma proteinopatia de tdp-43 Download PDF

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BR112014010161B1
BR112014010161B1 BR112014010161-2A BR112014010161A BR112014010161B1 BR 112014010161 B1 BR112014010161 B1 BR 112014010161B1 BR 112014010161 A BR112014010161 A BR 112014010161A BR 112014010161 B1 BR112014010161 B1 BR 112014010161B1
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tdp
antibody
seq
antibodies
binding
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BR112014010161-2A
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English (en)
Portuguese (pt)
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BR112014010161A2 (pt
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Roger Nitsch
Christoph Hock
Maria Grazia Barenco Montrasio
Fabio Montrasio
Jan Grimm
Jean-Luc Baeriswyl
Paul Weinreb
Janaky Coomaraswamy
Omar Quintero-Monzon
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Biogen International Neuroscience Gmbh
University Of Zurich
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Publication of BR112014010161A2 publication Critical patent/BR112014010161A2/pt
Publication of BR112014010161B1 publication Critical patent/BR112014010161B1/pt

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
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    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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    • G01—MEASURING; TESTING
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BR112014010161-2A 2011-10-28 2012-10-26 Anticorpo anti-proteína tar de ligação ao dna que possui 43 kda (tdp-43), seu método de preparação e seu uso, composições, polinucleotídeos, vetor, e kit útil no diagnóstico ou monitoramento da progressão de uma proteinopatia de tdp-43 BR112014010161B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161553113P 2011-10-28 2011-10-28
US61/553,113 2011-10-28
PCT/IB2012/002905 WO2013061163A2 (en) 2011-10-28 2012-10-26 Tdp-43 specific binding molecules

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Publication Number Publication Date
BR112014010161A2 BR112014010161A2 (pt) 2018-09-25
BR112014010161B1 true BR112014010161B1 (pt) 2022-02-08

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BR112014010161-2A BR112014010161B1 (pt) 2011-10-28 2012-10-26 Anticorpo anti-proteína tar de ligação ao dna que possui 43 kda (tdp-43), seu método de preparação e seu uso, composições, polinucleotídeos, vetor, e kit útil no diagnóstico ou monitoramento da progressão de uma proteinopatia de tdp-43

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US (3) US9587014B2 (enrdf_load_stackoverflow)
EP (2) EP3964524A1 (enrdf_load_stackoverflow)
JP (3) JP6240611B2 (enrdf_load_stackoverflow)
KR (2) KR102032080B1 (enrdf_load_stackoverflow)
CN (1) CN104159918B (enrdf_load_stackoverflow)
AU (1) AU2012327211C9 (enrdf_load_stackoverflow)
BR (1) BR112014010161B1 (enrdf_load_stackoverflow)
CA (2) CA3112082A1 (enrdf_load_stackoverflow)
CL (1) CL2014001074A1 (enrdf_load_stackoverflow)
EA (1) EA032003B1 (enrdf_load_stackoverflow)
ES (1) ES2883212T3 (enrdf_load_stackoverflow)
IL (2) IL232219B (enrdf_load_stackoverflow)
MX (2) MX357678B (enrdf_load_stackoverflow)
MY (1) MY167795A (enrdf_load_stackoverflow)
PH (1) PH12014500940A1 (enrdf_load_stackoverflow)
SG (1) SG11201401735WA (enrdf_load_stackoverflow)
WO (1) WO2013061163A2 (enrdf_load_stackoverflow)
ZA (1) ZA201403680B (enrdf_load_stackoverflow)

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