BR112014001309A2 - pulverização do ferimento - Google Patents
pulverização do ferimentoInfo
- Publication number
- BR112014001309A2 BR112014001309A2 BR112014001309A BR112014001309A BR112014001309A2 BR 112014001309 A2 BR112014001309 A2 BR 112014001309A2 BR 112014001309 A BR112014001309 A BR 112014001309A BR 112014001309 A BR112014001309 A BR 112014001309A BR 112014001309 A2 BR112014001309 A2 BR 112014001309A2
- Authority
- BR
- Brazil
- Prior art keywords
- myoglobin
- hemoglobin
- composition
- spraying
- wound
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0028—Polypeptides; Proteins; Degradation products thereof
- A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/41—Porphyrin- or corrin-ring-containing peptides
- A61K38/42—Haemoglobins; Myoglobins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0066—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0076—Sprayable compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3403—Regulation parameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M35/00—Devices for applying media, e.g. remedies, on the human body
- A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/805—Haemoglobins; Myoglobins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0429—Red blood cells; Erythrocytes
- A61M2202/0433—Free haemoglobin
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04C—ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
- F04C2270/00—Control; Monitoring or safety arrangements
- F04C2270/04—Force
- F04C2270/041—Controlled or regulated
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Materials Engineering (AREA)
- Medicinal Chemistry (AREA)
- Vascular Medicine (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
resumo patente de invenção: "pulverização do ferimento". a presente invenção refere-se a uma composição, compreendendo hemoglobina ou mioglobina, em que em pelo menos 40% da referida hemoglobina ou mioglobina o sítio de ligação de oxigênio é carregado por um ligante de não o2, e pelo menos um outro ingrediente, um método para a preparação da referida composição e o uso de hemoglobina ou mioglobina carregada com um ligante de não oxigênio para o tratamento externo de ferimentos. 20282558v1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11006057.1A EP2550973B1 (en) | 2011-07-23 | 2011-07-23 | Wound spray |
EP11006057.1 | 2011-07-23 | ||
PCT/EP2012/003086 WO2013013799A1 (en) | 2011-07-23 | 2012-07-23 | Wound spray |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112014001309A2 true BR112014001309A2 (pt) | 2017-02-21 |
BR112014001309B1 BR112014001309B1 (pt) | 2020-02-18 |
Family
ID=46604251
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014001309-8A BR112014001309B1 (pt) | 2011-07-23 | 2012-07-23 | Composição para pulverização de ferimento, seu processo de preparação, processo para purificação um veículo de oxigênio, e uso de hemoglobina ou mioglobina |
Country Status (22)
Country | Link |
---|---|
US (3) | US10646613B2 (pt) |
EP (2) | EP2550973B1 (pt) |
JP (1) | JP5995970B2 (pt) |
KR (1) | KR101900991B1 (pt) |
CN (2) | CN103781488A (pt) |
AU (1) | AU2012289237B2 (pt) |
BR (1) | BR112014001309B1 (pt) |
CA (1) | CA2842487C (pt) |
CL (1) | CL2014000172A1 (pt) |
CO (1) | CO6940380A2 (pt) |
EA (1) | EA030017B1 (pt) |
ES (2) | ES2432075T3 (pt) |
HK (1) | HK1177902A1 (pt) |
HU (1) | HUE029928T2 (pt) |
IL (1) | IL230160A (pt) |
MX (1) | MX2014000900A (pt) |
MY (1) | MY165035A (pt) |
PE (1) | PE20141577A1 (pt) |
PL (2) | PL2550973T3 (pt) |
UA (1) | UA113290C2 (pt) |
WO (1) | WO2013013799A1 (pt) |
ZA (1) | ZA201400078B (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10729748B2 (en) | 2012-01-13 | 2020-08-04 | Mölnlycke Health Care Ab | Scarring reducing wound treatment |
EP2614833A1 (en) * | 2012-01-13 | 2013-07-17 | SastoMed GmbH | Scarring reducing wound treatment |
DE102013014651A1 (de) * | 2013-09-03 | 2015-03-05 | Sanguibiotech Gmbh | Zubereitungen zur verbesserten Gewebe-Oxygenierung durch peritoneale Beatmung |
EP3421044A1 (en) | 2017-06-26 | 2019-01-02 | SastoMed GmbH | Oxygen carriers for the treatment of skin indispositions |
AU2018304174A1 (en) | 2017-07-18 | 2020-02-06 | VirTech Bio, Inc. | Blood substitutes comprising hemoglobin and methods of making |
GB201818811D0 (en) | 2018-11-19 | 2019-01-02 | Smith & Nephew | Method of immobilising a protein on a substrate |
US11506658B2 (en) | 2019-04-24 | 2022-11-22 | Progenitec, Inc. | System for analysis of body fluids and wound-associated biomolecules |
CN113609885A (zh) * | 2020-06-22 | 2021-11-05 | 王英婷 | 自适应舱门开关控制系统及方法 |
CN117100905A (zh) * | 2023-10-25 | 2023-11-24 | 润方(北京)生物医药研究院有限公司 | 促进伤口愈合的敷料 |
Family Cites Families (33)
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DE441893C (de) | 1927-03-14 | Max Mueller | Selbstdockendes Schwimmdock mit dreiteiligem Bodenkasten | |
DE357665C (de) | 1919-05-08 | 1922-08-29 | Felten & Guilleaume Carlswerk | Isoliermasse zur Abdichtung elektrischer Leitungen und Kabel |
DE371435C (de) | 1921-05-15 | 1923-03-15 | Norske Molybdenprodukter A S | Verfahren zur Reduktion von Molybdaen-Schwefelverbindungen |
DE384110C (de) | 1922-09-19 | 1923-11-03 | Fallert & Co A G | Vorrichtung zum Zentrieren der Spindel einer Massewalze in der Giessflasche |
US2527210A (en) | 1944-01-25 | 1950-10-24 | John O Bower | Hemoglobin solution and method |
DE1970137U (de) | 1967-04-01 | 1967-10-12 | Guenter Friebe | Satz kombinierbarer moebel-bauelemente. |
DE3320752A1 (de) | 1983-06-09 | 1984-12-13 | Wolfgang Prof. Dr.Dr. 6500 Mainz Barnikol | Lumineszierende schichten zur verwendung in vorrichtungen zur bestimmung der sauerstoffkonzentration in gasen und dergleichen durch messung der lumineszensverringerung |
US4776991A (en) * | 1986-08-29 | 1988-10-11 | The United States Of America As Represented By The Secretary Of The Navy | Scaled-up production of liposome-encapsulated hemoglobin |
DE3714351A1 (de) | 1987-04-29 | 1988-11-17 | Barnikol Wolfgang | Verfahren zur modifikation, insbesondere zur polymerisation von haemoglobin in vitro |
GB8710598D0 (en) * | 1987-05-05 | 1987-06-10 | Star Medical Diagnostics Ltd | Hemoglobin based blood substitute |
DE3841105C2 (de) | 1988-12-07 | 1994-09-01 | Wolfgang Karl Richard Barnikol | Verfahren zur Aufreinigung und Modifikation von polymerisiertem Hämoglobin |
US5840851A (en) * | 1993-07-23 | 1998-11-24 | Plomer; J. Jeffrey | Purification of hemoglobin |
DE4418937C2 (de) | 1994-02-28 | 2003-07-17 | Roesler Draht Ag | Klappgelenkmatte |
US5476764A (en) * | 1994-09-16 | 1995-12-19 | The Regents Of The University Of California | Method using CO for extending the useful shelf-life of refrigerated red blood cells |
EP1211261A3 (en) | 1995-03-23 | 2004-03-17 | Biopure Corporation | Stable polymerized hemoglobin blood-substitute |
JPH11513709A (ja) | 1995-10-26 | 1999-11-24 | バクスター・インターナショナル・インコーポレイテッド | 創傷治療の促進におけるヘモグロビンの治療的使用 |
DE19701037A1 (de) * | 1997-01-15 | 1998-07-16 | Sanguibiotech Ag | Mit Schutzliganden der Sauerstoffbindungsstellen versehene Hämoglobine als künstliche Sauerstoffträger zur direkten biologisch-medizinischen Anwendung und Verfahren zu ihrer Herstellung |
EP0854151A1 (de) | 1997-01-20 | 1998-07-22 | SanguiBioTech AG | Verfahren zur Gewinnung einheitlicher Fraktionen hyperpolymerer Hämoglobine |
DE19933275A1 (de) * | 1999-07-14 | 2001-01-18 | Fresenius Ag | Verwendung von Hämoglobin-Derivaten zur Bestimmung des Plasma- und/oder Blutvolumens |
US6670323B1 (en) | 1999-11-12 | 2003-12-30 | Baxter International, Inc. | Reduced side-effect hemoglobin compositions |
DE10031741A1 (de) * | 2000-06-29 | 2002-01-17 | Sanguibio Tech Ag | Einen Sauerstoffträger, ausgewählt aus Hämoglobin oder Hämoglobin- und Myoglobin-enthaltende Zubereitung als Externum zur natürlichen Regeneration der Haut bei Sauerstoff-Mangel |
DE10031742A1 (de) | 2000-06-29 | 2002-01-17 | Sanguibio Tech Ag | Verfahren zur Herstellung künstlicher Sauerstoffträger aus kovalent vernetzten Hämoglobinen mit verbesserten funktionellen Eigenschaften durch Vernetzung in Anwesenheit chemisch nicht reagierender Effektoren der Sauerstoffaffinität der Hämoglobine |
DE10031744A1 (de) | 2000-06-29 | 2002-01-17 | Sanguibio Tech Ag | Mit Blutplasma verträgliche, vernetzte und mit Polyalkylenoxiden konjugierte Säugetierhämoglobine als künstliche medizinische Sauerstoffträger, ihre Herstellung und ihre Verwendung |
DE10031740A1 (de) | 2000-06-29 | 2002-02-14 | Sanguibio Tech Ag | Künstliche Sauerstoffträger aus vernetztem modifizierten Human- oder Schweinehämoglobin mit verbesserten Eigenschaften, Verfahren zu ihrer technisch einfachen Herstellung aus gereinigtem Material in hohen Ausbeuten, sowie deren Verwendung |
US6518010B2 (en) * | 2001-02-28 | 2003-02-11 | Biopure Corporation | Use of defibrinated blood for manufacture of a hemoglobin-based oxygen carrier |
DE10212321A1 (de) | 2002-03-20 | 2003-10-09 | Sanguibio Tech Ag | Verwendung eines oder mehrerer von Plasma und Zellwandbestandteilen befreiten natürlichen oder modifizierten Sauerstoffbinder zur externen Behandlung offener, insbesondere chronischer Wunden |
IL149611A (en) | 2002-05-13 | 2011-07-31 | Safetin Ltd | Method for extended storage of viable and pathogen-safe blood and blood components using carbon monoxide |
CN1905901A (zh) | 2004-01-29 | 2007-01-31 | 学校法人庆应义塾 | 红细胞功能修饰物质 |
CN1786018B (zh) * | 2005-12-12 | 2011-06-22 | 天津协和生物科技发展有限公司 | 高纯度血红蛋白的分离纯化与病毒灭活工艺 |
US20100035798A1 (en) * | 2006-09-15 | 2010-02-11 | The Ohio State University Research Foundation | Methods and compositions for the topical oxygenation of hypoxic tissue |
FR2917292B1 (fr) * | 2007-06-18 | 2014-06-13 | Centre Nat Rech Scient | Utilisation d'une hemoglobine pour la preparation de pansements, et pansements ainsi prepares |
NO2440239T3 (pt) | 2009-06-09 | 2018-02-10 | ||
CN101948630B (zh) * | 2010-09-10 | 2013-02-27 | 合肥工业大学 | 利用畜禽血液制备碳氧血红蛋白的方法 |
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2011
- 2011-07-23 EP EP11006057.1A patent/EP2550973B1/en active Active
- 2011-07-23 PL PL11006057T patent/PL2550973T3/pl unknown
- 2011-07-23 ES ES11006057T patent/ES2432075T3/es active Active
-
2012
- 2012-07-23 CA CA2842487A patent/CA2842487C/en active Active
- 2012-07-23 PL PL12743076T patent/PL2734223T3/pl unknown
- 2012-07-23 MX MX2014000900A patent/MX2014000900A/es active IP Right Grant
- 2012-07-23 JP JP2014521979A patent/JP5995970B2/ja active Active
- 2012-07-23 PE PE2014000111A patent/PE20141577A1/es not_active Application Discontinuation
- 2012-07-23 KR KR1020147000816A patent/KR101900991B1/ko active IP Right Grant
- 2012-07-23 BR BR112014001309-8A patent/BR112014001309B1/pt active IP Right Grant
- 2012-07-23 ES ES12743076.7T patent/ES2593530T3/es active Active
- 2012-07-23 AU AU2012289237A patent/AU2012289237B2/en active Active
- 2012-07-23 CN CN201280036457.7A patent/CN103781488A/zh active Pending
- 2012-07-23 WO PCT/EP2012/003086 patent/WO2013013799A1/en active Application Filing
- 2012-07-23 UA UAA201401698A patent/UA113290C2/uk unknown
- 2012-07-23 MY MYPI2014000201A patent/MY165035A/en unknown
- 2012-07-23 EP EP12743076.7A patent/EP2734223B1/en active Active
- 2012-07-23 CN CN201810501606.1A patent/CN108752468B/zh active Active
- 2012-07-23 US US14/131,022 patent/US10646613B2/en active Active
- 2012-07-23 EA EA201490319A patent/EA030017B1/ru unknown
- 2012-07-23 HU HUE12743076A patent/HUE029928T2/en unknown
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2013
- 2013-05-14 HK HK13105707.8A patent/HK1177902A1/xx unknown
- 2013-12-25 IL IL230160A patent/IL230160A/en active IP Right Grant
-
2014
- 2014-01-06 ZA ZA2014/00078A patent/ZA201400078B/en unknown
- 2014-01-21 CO CO14011086A patent/CO6940380A2/es unknown
- 2014-01-22 CL CL2014000172A patent/CL2014000172A1/es unknown
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2016
- 2016-04-21 US US15/134,764 patent/US10471175B2/en active Active
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2020
- 2020-03-31 US US16/835,662 patent/US11116868B2/en active Active
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Legal Events
Date | Code | Title | Description |
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
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