BR112013031019A2 - teste diagnóstico molecular para câncer - Google Patents
teste diagnóstico molecular para câncerInfo
- Publication number
- BR112013031019A2 BR112013031019A2 BR112013031019A BR112013031019A BR112013031019A2 BR 112013031019 A2 BR112013031019 A2 BR 112013031019A2 BR 112013031019 A BR112013031019 A BR 112013031019A BR 112013031019 A BR112013031019 A BR 112013031019A BR 112013031019 A2 BR112013031019 A2 BR 112013031019A2
- Authority
- BR
- Brazil
- Prior art keywords
- cancer
- diagnostic test
- molecular diagnostic
- molecular
- test
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57545—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the ovaries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57557—Immunoassay; Biospecific binding assay; Materials therefor for cancer of other specific parts of the body, e.g. brain
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7014—(Neo)vascularisation - Angiogenesis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161492488P | 2011-06-02 | 2011-06-02 | |
| PCT/US2012/040805 WO2012167278A1 (en) | 2011-06-02 | 2012-06-04 | Molecular diagnostic test for cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013031019A2 true BR112013031019A2 (pt) | 2017-03-21 |
Family
ID=47259970
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013031019A BR112013031019A2 (pt) | 2011-06-02 | 2012-06-04 | teste diagnóstico molecular para câncer |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US10260097B2 (https=) |
| EP (1) | EP2715348B1 (https=) |
| JP (2) | JP6067686B2 (https=) |
| KR (1) | KR20140044341A (https=) |
| CN (1) | CN103733065B (https=) |
| AU (1) | AU2012261820B2 (https=) |
| BR (1) | BR112013031019A2 (https=) |
| CA (1) | CA2838086A1 (https=) |
| EA (2) | EA025926B1 (https=) |
| IL (1) | IL229681A0 (https=) |
| MX (1) | MX2013014065A (https=) |
| SG (2) | SG195208A1 (https=) |
| WO (1) | WO2012167278A1 (https=) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112013031019A2 (pt) | 2011-06-02 | 2017-03-21 | Almac Diagnostics Ltd | teste diagnóstico molecular para câncer |
| EP2667193A1 (en) * | 2012-05-23 | 2013-11-27 | Université d'Aix-Marseille | MMP2 as a predictive biomarker of response to antiangiogenic therapy and survival after therapy in cancer patients |
| WO2014055398A1 (en) * | 2012-10-05 | 2014-04-10 | Siemens Healthcare Diagnostics Inc. | Method for detecting an increased risk or incidence of colorectal cancer |
| MX2015006955A (es) * | 2012-12-03 | 2016-01-25 | Almac Diagnostics Ltd | Prueba de diagnostico molecular para cancer. |
| GB201313342D0 (en) * | 2013-07-26 | 2013-09-11 | Cancer Rec Tech Ltd | Biomarkers |
| US10617755B2 (en) | 2013-08-30 | 2020-04-14 | Genentech, Inc. | Combination therapy for the treatment of glioblastoma |
| US10456470B2 (en) | 2013-08-30 | 2019-10-29 | Genentech, Inc. | Diagnostic methods and compositions for treatment of glioblastoma |
| GB201409479D0 (en) | 2014-05-28 | 2014-07-09 | Almac Diagnostics Ltd | Molecular diagnostic test for cancer |
| GB201409476D0 (en) * | 2014-05-28 | 2014-07-09 | Almac Diagnostics Ltd | Molecular subtype for use in prognosis |
| GB201409478D0 (en) * | 2014-05-28 | 2014-07-09 | Almac Diagnostics Ltd | Pro-angiogenic signature |
| WO2016011052A1 (en) * | 2014-07-14 | 2016-01-21 | Genentech, Inc. | Diagnostic methods and compositions for treatment of glioblastoma |
| WO2016028638A1 (en) * | 2014-08-18 | 2016-02-25 | Drexel University | Methods, computer-readable media, and systems for assessing samples and wounds, predicting whether a wound will heal, and monitoring effectiveness of a treatment |
| WO2016133374A1 (ko) * | 2015-02-17 | 2016-08-25 | 싸이퍼롬, 인코퍼레이티드 | 자궁수축억제제 부작용 방지를 위한 개인별 단백질 손상 정보 기반의 자궁수축억제제 선택 방법 |
| CN105160208A (zh) * | 2015-05-29 | 2015-12-16 | 杭州奥视图像技术有限公司 | 用于疾病亚型问题的基于网络的聚类方法 |
| CN108026154B (zh) | 2015-07-01 | 2022-03-08 | 伊玛提克斯生物技术有限公司 | 用于卵巢癌和其他癌症免疫治疗的新型肽和肽组合物 |
| GB201511546D0 (en) | 2015-07-01 | 2015-08-12 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers |
| US10650325B2 (en) * | 2015-07-31 | 2020-05-12 | Microsoft Technology Licensing, Llc | Deterministic message distribution |
| US11174518B2 (en) | 2015-10-05 | 2021-11-16 | Cedars-Sinai Medical Center | Method of classifying and diagnosing cancer |
| JP6942135B2 (ja) * | 2016-01-25 | 2021-09-29 | サノフイSanofi | 血漿バイオマーカーのレベルを測定することによる、がんに罹患していることが疑われる患者のアフリベルセプトによる治療の転帰を予測するための方法 |
| US20190127805A1 (en) * | 2016-03-15 | 2019-05-02 | Almac Diagnostics Limited | Gene signatures for cancer detection and treatment |
| JP6899848B2 (ja) | 2016-12-28 | 2021-07-07 | 公益財団法人がん研究会 | 抗vegfr−2抗体医薬品の治療効果を予測するバイオマーカー、検査方法、及び検査キット |
| CN107037210A (zh) * | 2017-04-05 | 2017-08-11 | 北京蛋白质组研究中心 | Thbs2蛋白检测物在制备肝细胞癌诊断试剂盒中的应用 |
| US20200200760A1 (en) * | 2017-05-16 | 2020-06-25 | Lankenau Institute Of Medical Research | Compositions comprising ligands to rhob protein and the uses thereof |
| EP3879535B1 (en) * | 2017-06-13 | 2024-12-11 | BostonGene Corporation | Systems and methods for identifying cancer treatments from normalized biomarker scores |
| JP7316270B2 (ja) * | 2017-06-19 | 2023-07-27 | インビタエ コーポレイション | 統合算出および実験的深層変異学習フレームワークを介した遺伝子およびゲノム変異体の解釈 |
| EP3461916A1 (en) | 2017-10-02 | 2019-04-03 | Koninklijke Philips N.V. | Assessment of jak-stat3 cellular signaling pathway activity using mathematical modelling of target gene expression |
| EP3461915A1 (en) | 2017-10-02 | 2019-04-03 | Koninklijke Philips N.V. | Assessment of jak-stat1/2 cellular signaling pathway activity using mathematical modelling of target gene expression |
| EP3502279A1 (en) | 2017-12-20 | 2019-06-26 | Koninklijke Philips N.V. | Assessment of mapk-ap 1 cellular signaling pathway activity using mathematical modelling of target gene expression |
| WO2019165366A1 (en) * | 2018-02-23 | 2019-08-29 | Beth Israel Deaconess Medical Center | Drug efficacy evaluations |
| JP7455757B2 (ja) * | 2018-04-13 | 2024-03-26 | フリーノーム・ホールディングス・インコーポレイテッド | 生体試料の多検体アッセイのための機械学習実装 |
| CN113292537B (zh) | 2018-06-15 | 2024-04-05 | 汉达癌症医药责任有限公司 | 激酶抑制剂的盐类及其组合物 |
| CN112955260A (zh) * | 2018-06-27 | 2021-06-11 | 定量癌症诊断有限责任公司 | 生物样品保持器和处理器 |
| CN109585011A (zh) * | 2018-10-26 | 2019-04-05 | 朱海燕 | 胸痛患者的病症诊断方法及机器可读存储介质 |
| MX2021005646A (es) * | 2018-11-14 | 2021-08-11 | Beyondspring Pharmaceuticals Inc | Métodos de tratamiento de cáncer con agentes de unión a tubulina. |
| WO2021016402A1 (en) * | 2019-07-22 | 2021-01-28 | Mission Bio, Inc. | Using machine learning to optimize assays for single cell targeted dna sequencing |
| KR102289533B1 (ko) * | 2019-08-19 | 2021-08-17 | 주식회사 테라젠바이오 | 특정 약물의 타겟 유전자와 관련된 시그니처를 기초로 타겟 유전자와 관련된 유전자들을 판단하는 전자 장치, 방법 및 상기 방법을 실행하기 위한 컴퓨터 프로그램 |
| US11049590B1 (en) | 2020-02-12 | 2021-06-29 | Peptilogics, Inc. | Artificial intelligence engine architecture for generating candidate drugs |
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| PE20230609A1 (es) * | 2020-05-04 | 2023-04-13 | Amgen Inc | Compuestos heterociclicos como agonistas del receptor de activacion expresado en las celulas mieloides 2 y metodos de uso |
| CN112489800B (zh) * | 2020-12-03 | 2024-05-28 | 安徽医科大学第一附属医院 | 一种前列腺癌患者的预后评估系统及其应用 |
| CN116312814B (zh) * | 2021-12-02 | 2024-09-27 | 复旦大学 | 一种肺腺癌分子分型模型的构建方法、设备、装置以及试剂盒 |
| CN114624441B (zh) * | 2022-03-04 | 2025-07-18 | 中国人民解放军空军军医大学 | 跨膜蛋白43作为胰腺癌肿瘤诊断标志物的应用 |
| CN115902223B (zh) * | 2022-11-15 | 2025-08-26 | 中国人民解放军空军军医大学 | 蛋白生物标志物在胃癌诊断中的应用 |
| CN116863995B (zh) * | 2023-08-29 | 2024-05-14 | 北京大学第一医院 | Alpk2,itga11,esyt1,cdh17在预测药物出血中的应用 |
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- 2012-06-04 BR BR112013031019A patent/BR112013031019A2/pt not_active IP Right Cessation
- 2012-06-04 CN CN201280037298.2A patent/CN103733065B/zh not_active Expired - Fee Related
- 2012-06-04 KR KR1020137034588A patent/KR20140044341A/ko not_active Ceased
- 2012-06-04 JP JP2014513800A patent/JP6067686B2/ja not_active Expired - Fee Related
- 2012-06-04 US US14/123,406 patent/US10260097B2/en not_active Expired - Fee Related
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- 2012-06-04 CA CA2838086A patent/CA2838086A1/en not_active Abandoned
- 2012-06-04 EA EA201391805A patent/EA025926B1/ru not_active IP Right Cessation
- 2012-06-04 MX MX2013014065A patent/MX2013014065A/es unknown
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- 2012-06-04 WO PCT/US2012/040805 patent/WO2012167278A1/en not_active Ceased
- 2012-06-04 EA EA201691257A patent/EA201691257A1/ru unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| CN103733065B (zh) | 2017-12-15 |
| JP6067686B2 (ja) | 2017-01-25 |
| EP2715348B1 (en) | 2019-04-10 |
| JP2014516552A (ja) | 2014-07-17 |
| EA201391805A1 (ru) | 2014-03-31 |
| NZ618191A (en) | 2015-04-24 |
| KR20140044341A (ko) | 2014-04-14 |
| EP2715348A1 (en) | 2014-04-09 |
| US20140342924A1 (en) | 2014-11-20 |
| US10260097B2 (en) | 2019-04-16 |
| IL229681A0 (en) | 2014-01-30 |
| EA025926B1 (ru) | 2017-02-28 |
| WO2012167278A1 (en) | 2012-12-06 |
| CA2838086A1 (en) | 2012-12-06 |
| SG195208A1 (en) | 2013-12-30 |
| AU2012261820B2 (en) | 2017-01-19 |
| JP2017079772A (ja) | 2017-05-18 |
| EA201691257A1 (ru) | 2017-02-28 |
| MX2013014065A (es) | 2014-06-23 |
| EP2715348A4 (en) | 2015-10-07 |
| SG10201604497UA (en) | 2016-07-28 |
| CN103733065A (zh) | 2014-04-16 |
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