BR112013027153A2 - método de aplicação de fármaco para pth, pthrp e peptídeos relacionados - Google Patents

método de aplicação de fármaco para pth, pthrp e peptídeos relacionados

Info

Publication number
BR112013027153A2
BR112013027153A2 BR112013027153A BR112013027153A BR112013027153A2 BR 112013027153 A2 BR112013027153 A2 BR 112013027153A2 BR 112013027153 A BR112013027153 A BR 112013027153A BR 112013027153 A BR112013027153 A BR 112013027153A BR 112013027153 A2 BR112013027153 A2 BR 112013027153A2
Authority
BR
Brazil
Prior art keywords
pthrp
pth
related peptides
drug application
application method
Prior art date
Application number
BR112013027153A
Other languages
English (en)
Portuguese (pt)
Inventor
Amy S Determan
Gary Hattersley
Kris J Hansen
Ying Zhang
Original Assignee
3M Innovative Properties Co
Radius Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co, Radius Health Inc filed Critical 3M Innovative Properties Co
Publication of BR112013027153A2 publication Critical patent/BR112013027153A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/29Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
BR112013027153A 2011-04-22 2012-04-20 método de aplicação de fármaco para pth, pthrp e peptídeos relacionados BR112013027153A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161478466P 2011-04-22 2011-04-22
US201161578120P 2011-12-20 2011-12-20
PCT/US2012/034510 WO2012145665A2 (en) 2011-04-22 2012-04-20 Method of drug delivery for pth, pthrp and related peptides

Publications (1)

Publication Number Publication Date
BR112013027153A2 true BR112013027153A2 (pt) 2016-11-29

Family

ID=47042187

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013027153A BR112013027153A2 (pt) 2011-04-22 2012-04-20 método de aplicação de fármaco para pth, pthrp e peptídeos relacionados

Country Status (14)

Country Link
US (6) US20130006217A1 (https=)
EP (2) EP2699252B1 (https=)
JP (2) JP6033280B2 (https=)
KR (1) KR20140047043A (https=)
CN (1) CN103917242A (https=)
AU (2) AU2012245301B2 (https=)
BR (1) BR112013027153A2 (https=)
CA (1) CA2833571A1 (https=)
ES (1) ES2648864T3 (https=)
IL (1) IL228942A0 (https=)
MX (1) MX2013012349A (https=)
RU (1) RU2013151314A (https=)
SG (1) SG194570A1 (https=)
WO (1) WO2012145665A2 (https=)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE030072T2 (en) 2010-05-12 2017-04-28 Radius Health Inc Therapeutic prescriptions
US20130158482A1 (en) * 2010-07-26 2013-06-20 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
US9133182B2 (en) 2010-09-28 2015-09-15 Radius Health, Inc. Selective androgen receptor modulators
WO2012064802A1 (en) 2010-11-09 2012-05-18 Seventh Sense Biosystems, Inc. Systems and interfaces for blood sampling
KR102143482B1 (ko) 2011-11-30 2020-08-11 쓰리엠 이노베이티브 프로퍼티즈 컴파니 펩티드 치료제 및 아미노산을 포함하는 마이크로니들 장치, 이의 제조 및 사용 방법
CN104602752A (zh) * 2012-08-30 2015-05-06 帝人株式会社 涂布有药物组合物的微针阵列
ES3055185T3 (en) 2014-03-28 2026-02-10 Univ Duke Treatment of an estrogen receptor positive breast cancer using a selective estrogen receptor modulator
CA2977812A1 (en) * 2015-03-03 2016-09-09 Radius Health, Inc. Uses of pthrp analogue in reducing fracture risk
KR20250152679A (ko) 2015-04-29 2025-10-23 래디어스 파마슈티컬스, 인코포레이티드 암을 치료하는 방법
CN108025042A (zh) * 2015-07-06 2018-05-11 董正欣 PTHrP类似物的新型制剂
WO2017062727A1 (en) 2015-10-09 2017-04-13 3M Innovative Properties Company Zinc compositions for coated microneedle arrays
KR20180067573A (ko) * 2015-10-09 2018-06-20 라디우스 헬쓰, 인코포레이티드 PTHrP 유사체의 제형, 이의 경피 패취, 및 이의 용도
US10568937B2 (en) * 2016-04-18 2020-02-25 Radius Health, Inc. Formulations of abaloparatide, transdermal patches thereof, and uses thereof
MX389702B (es) 2016-06-22 2025-03-20 Ellipses Pharma Ltd Compuestos para usarse en el tratamiento de cancer de mama que expresa el receptor de androgenos (ar+).
CA3045458A1 (en) * 2016-11-30 2018-06-07 Purdue Research Foundation Fracture targeted bone regeneration through parathyroid hormone receptor stimulation
JP7481115B2 (ja) 2017-01-05 2024-05-10 ラジウス ファーマシューティカルズ,インコーポレイテッド Rad1901-2hclの多形性形態
US9968767B1 (en) 2017-10-10 2018-05-15 King Saud University Combination microarray patch for drug delivery and electrochemotherapy device
WO2019232283A1 (en) 2018-05-30 2019-12-05 Purdue Research Foundation Targeting anabolic drugs for accelerated fracture repair
MX2020013713A (es) 2018-07-04 2021-03-02 Radius Pharmaceuticals Inc Formas polimorficas de rad1901-2hcl.
EP3924328A1 (en) 2019-02-12 2021-12-22 Radius Pharmaceuticals, Inc. Processes and compounds
EP4110371A1 (en) 2020-01-24 2023-01-04 Radius Health, Inc. Methods of stimulating bone growth with abalopartide and denosumab
JP2023523952A (ja) 2020-04-28 2023-06-08 ティコナ・エルエルシー マイクロニードルアセンブリ
US20230210762A1 (en) * 2020-05-01 2023-07-06 Emergex USA Corporation Transdermal drug delivery devices having psilocybin, lysergic acid diethylamide or 3,4-methylenedioxymethamphetamine coated microprotrusions
WO2022149066A1 (en) * 2021-01-05 2022-07-14 Radius Health, Inc. Treatment of long bone fractures with abaloparatide
US12178979B2 (en) 2021-10-13 2024-12-31 Satio, Inc. Dermal patch for delivering a pharmaceutical
US12214346B2 (en) 2021-10-13 2025-02-04 Satio, Inc. Dermal patch with a diagnostic test strip
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US12053284B2 (en) 2021-11-08 2024-08-06 Satio, Inc. Dermal patch for collecting a physiological sample
US12023156B2 (en) 2021-10-13 2024-07-02 Satio, Inc. Dermal patch for collecting a physiological sample
US12048543B2 (en) 2021-11-08 2024-07-30 Satio, Inc. Dermal patch for collecting a physiological sample with removable vial
US11452474B1 (en) 2021-04-14 2022-09-27 Satio, Inc. Dual lever dermal patch system
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544949B1 (en) * 1995-07-13 2003-04-08 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Analogs of parathyroid hormone
US5969095A (en) 1995-07-13 1999-10-19 Biomeasure, Inc. Analogs of parathyroid hormone
CA2313698C (en) * 1997-12-11 2008-04-15 Alza Corporation Device for enhancing transdermal agent flux
DE69806963T2 (de) * 1997-12-11 2002-11-21 Alza Corp., Mountain View Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
US6091975A (en) * 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device
GB9930882D0 (en) * 1999-12-30 2000-02-23 Nps Allelix Corp GLP-2 formulations
JP2007535337A (ja) * 2003-10-28 2007-12-06 アルザ・コーポレーシヨン 被覆された微小突起による治療用ペプチドおよびタンパクのポリマー接合体の送達
ES2377647T3 (es) * 2003-10-31 2012-03-29 Alza Corporation Aplicador auto-actuado para ordenamiento de microproyecciones
KR20070010115A (ko) * 2003-11-13 2007-01-22 알자 코포레이션 경피전달용 조성물 및 장치
US7556821B2 (en) 2004-05-13 2009-07-07 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
US8632801B2 (en) * 2005-12-28 2014-01-21 Alza Corporation Stable therapeutic formulations
AU2007225056A1 (en) * 2006-03-15 2007-09-20 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents to prevent or treat osteopenia
US9119945B2 (en) 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
US8048383B2 (en) * 2006-04-20 2011-11-01 Velocys, Inc. Process for treating and/or forming a non-Newtonian fluid using microchannel process technology
US7803770B2 (en) * 2006-10-03 2010-09-28 Radius Health, Inc. Method of treating osteoporosis comprising administration of PTHrP analog
BRPI0719821B8 (pt) * 2006-10-03 2021-05-25 Ipsen Pharma Sas composição estável na armazenagem apropriada para administração a pacientes
EP2119469B1 (en) * 2007-02-06 2014-05-14 Hisamitsu Pharmaceutical Co., Inc. Microneedle device for diagnosis of allergy
US9549746B2 (en) * 2007-09-28 2017-01-24 The Queen's University Of Belfast Delivery device and method
WO2009054988A1 (en) * 2007-10-23 2009-04-30 Alza Corporation Transdermal sustained release drug delivery
EP2052736A1 (en) * 2007-10-26 2009-04-29 Nycomed Danmark ApS Parathyroid hormone formulations und uses thereof
KR101668502B1 (ko) 2008-11-04 2016-10-21 아스카 세이야쿠 가부시키가이샤 난포자극호르몬 함유 수성 조성물
US20110172609A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Microneedle component assembly for drug delivery device

Also Published As

Publication number Publication date
NZ618003A (en) 2016-05-27
CN103917242A (zh) 2014-07-09
JP6033280B2 (ja) 2016-11-30
ES2648864T3 (es) 2018-01-08
US20140046293A1 (en) 2014-02-13
AU2016216584A1 (en) 2016-09-01
JP2014517825A (ja) 2014-07-24
MX2013012349A (es) 2014-07-09
US20130006217A1 (en) 2013-01-03
KR20140047043A (ko) 2014-04-21
US20190290738A1 (en) 2019-09-26
EP3332799A1 (en) 2018-06-13
US20170189493A1 (en) 2017-07-06
WO2012145665A2 (en) 2012-10-26
IL228942A0 (en) 2013-12-31
CA2833571A1 (en) 2012-10-26
RU2013151314A (ru) 2015-05-27
WO2012145665A3 (en) 2014-04-24
US20140046292A1 (en) 2014-02-13
SG194570A1 (en) 2013-12-30
EP2699252A2 (en) 2014-02-26
JP2017036323A (ja) 2017-02-16
EP2699252B1 (en) 2017-10-25
AU2012245301B2 (en) 2016-05-19
EP2699252A4 (en) 2015-05-27
US20210052705A1 (en) 2021-02-25

Similar Documents

Publication Publication Date Title
BR112013027153A2 (pt) método de aplicação de fármaco para pth, pthrp e peptídeos relacionados
MX354101B (es) FORMULACION PARA ANTICUERPO ANTI -A4ß7.
BR112014030714A2 (pt) composto de lipídeo ionizável , composições , carreador de fármaco , formulação farmacêutica e método de entrega de um fármaco
IL254879B (en) History of dolastatin associated with unnatural amino acids and pharmaceutical preparations containing them
CY1116987T1 (el) Συμπυκνωμενα ιμιδαζολυλιμιδαζολια ως αντιϊικες ενωσεις
PH12014500715A1 (en) Treatment of rhinitis
UA109949C2 (uk) Композиція і лікарський засіб, які містять ідуронат-2-сульфатазу, і спосіб їх отримання
MY161773A (en) Amylin analogues and pharmaceutical compositions thereof
BR112014013780A2 (pt) transportador de seringa
BR112014007203A2 (pt) composto, composição farmacêutica, método de tratamento, utilização de um composto, conjunto e invenção
BR112014008126A2 (pt) composto, método para o tratamento, composição farmacêutica, utilização de um composto e invenção
BR112015016930A2 (pt) formulações farmacêuticas estabilizadas de análogos de insulina e/ou derivados de insulina
IL229260A0 (en) Preparations, methods and systems for respiratory administration of two or more active agents
SV2017005515A (es) Formulaciones de polvo nasal para el tratamiento de la hipoglicemia
BR112012029595A2 (pt) spray nasal líquido contendo naltrexona de baixa concentração
BR112015008297A2 (pt) antagonistas de mglu2/3 para o tratamento de distúrbios autistas
EA201490756A1 (ru) Разагилина цитрамид
BR112014015084A2 (pt) chocolate aerado
BR112013019513A2 (pt) métodos para o tratamento de úlceras diabéticas do pé
BR112013031575A2 (pt) composto peptídico ciclado de estrutura principal, composição farmacêutica, uso de composto, e, processo para a manufatura de um composto.
WO2012119004A3 (en) Parathyroid hormone analogs, compositions and uses thereof
BR112014009760A8 (pt) análogos de ácido siálico
BR112015005738A2 (pt) formulações orais de angiotensina
MY168931A (en) Therapeutic agent for arthrosis
EP2692348A4 (en) Antitumor agents containing carbohydrate dioxide as an active ingredient

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO ARQUIVAMENTO PUBLICADO NA RPI 2510 DE 12/02/2019.