BR112013022662B1 - Dispositivo de coleta de sangue contendo inibidor de lisofosfolipase e métodos para diagnosticar uma doença metabólica ou monitorar o tratamento de um paciente com uma doença metabólica e para detectar a presença ou quantidade de um pró-fármaco e/ou metabólito ativo do mesmo no sangue ou componente do mesmo - Google Patents

Dispositivo de coleta de sangue contendo inibidor de lisofosfolipase e métodos para diagnosticar uma doença metabólica ou monitorar o tratamento de um paciente com uma doença metabólica e para detectar a presença ou quantidade de um pró-fármaco e/ou metabólito ativo do mesmo no sangue ou componente do mesmo Download PDF

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Publication number
BR112013022662B1
BR112013022662B1 BR112013022662-5A BR112013022662A BR112013022662B1 BR 112013022662 B1 BR112013022662 B1 BR 112013022662B1 BR 112013022662 A BR112013022662 A BR 112013022662A BR 112013022662 B1 BR112013022662 B1 BR 112013022662B1
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BR
Brazil
Prior art keywords
inhibitor
fact
blood
tetrahydroacridin
stabilizing agent
Prior art date
Application number
BR112013022662-5A
Other languages
English (en)
Portuguese (pt)
Other versions
BR112013022662A2 (pt
Inventor
David Craft
Priyanka Apte
Original Assignee
Becton, Dickinson And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton, Dickinson And Company filed Critical Becton, Dickinson And Company
Publication of BR112013022662A2 publication Critical patent/BR112013022662A2/pt
Publication of BR112013022662B1 publication Critical patent/BR112013022662B1/pt

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/15003—Source of blood for venous or arterial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/14—Devices for taking samples of blood ; Measuring characteristics of blood in vivo, e.g. gas concentration within the blood, pH-value of blood
    • A61B5/1405—Devices for taking blood samples
    • A61B5/1438—Devices for taking blood samples using pre-evacuated means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061—Means for enhancing collection
    • A61B5/150099—Means for enhancing collection by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150251—Collection chamber divided into at least two compartments, e.g. for division of samples
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150351—Caps, stoppers or lids for sealing or closing a blood collection vessel or container, e.g. a test-tube or syringe barrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150389—Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150755—Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/154—Devices using pre-evacuated means

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • External Artificial Organs (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR112013022662-5A 2011-03-04 2012-03-02 Dispositivo de coleta de sangue contendo inibidor de lisofosfolipase e métodos para diagnosticar uma doença metabólica ou monitorar o tratamento de um paciente com uma doença metabólica e para detectar a presença ou quantidade de um pró-fármaco e/ou metabólito ativo do mesmo no sangue ou componente do mesmo BR112013022662B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161449337P 2011-03-04 2011-03-04
US61/449.337 2011-03-04
PCT/US2012/027391 WO2012121998A1 (en) 2011-03-04 2012-03-02 Blood collection device containing lysophospholipase inhibitor

Publications (2)

Publication Number Publication Date
BR112013022662A2 BR112013022662A2 (pt) 2017-06-27
BR112013022662B1 true BR112013022662B1 (pt) 2021-11-23

Family

ID=45852729

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013022662-5A BR112013022662B1 (pt) 2011-03-04 2012-03-02 Dispositivo de coleta de sangue contendo inibidor de lisofosfolipase e métodos para diagnosticar uma doença metabólica ou monitorar o tratamento de um paciente com uma doença metabólica e para detectar a presença ou quantidade de um pró-fármaco e/ou metabólito ativo do mesmo no sangue ou componente do mesmo

Country Status (12)

Country Link
US (1) US9459187B2 (enExample)
EP (1) EP2681554B1 (enExample)
JP (1) JP5844826B2 (enExample)
CN (2) CN203203992U (enExample)
AU (1) AU2012225810B2 (enExample)
BR (1) BR112013022662B1 (enExample)
CA (1) CA2828761C (enExample)
ES (1) ES2645022T3 (enExample)
MX (1) MX347230B (enExample)
RU (1) RU2623049C2 (enExample)
WO (1) WO2012121998A1 (enExample)
ZA (1) ZA201306591B (enExample)

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CN106604780B (zh) * 2015-03-10 2019-06-25 贝克顿·迪金森公司 生物流体微样本管理装置
JP6907188B2 (ja) 2015-08-13 2021-07-21 ダイアックス コーポレーション 接触系活性化の評価のためのプロテアーゼ阻害剤を含む真空採血管
CN105372109A (zh) * 2015-12-15 2016-03-02 苏州药明康德新药开发股份有限公司 添加稳定剂的生物基质的制备方法
CN106215993B (zh) * 2016-07-27 2023-07-28 上海凯戎医疗科技有限公司 一种无菌医用离心管及其用于制备富血小板血浆的制备方法
CN108174843B (zh) * 2018-01-24 2018-11-13 广州市进德生物科技有限公司 一种胰高血糖素保护剂及其应用
BR112020022230A2 (pt) * 2018-05-01 2021-02-02 Becton, Dickinson And Company tampa com plugue de ventilação para dispositivo de coleta de fluido biológico
DE102018218739B3 (de) * 2018-11-01 2020-03-19 Sarstedt Ag & Co. Kg Blutentnahmeröhre und Verfahren zur Präparation
RU198611U1 (ru) * 2019-07-10 2020-07-21 Линд Виталий Викторович Устройство для пробоподготовки крови при проведении жидкостной биопсии с рекомбинантным белком
US12434889B2 (en) 2022-12-09 2025-10-07 Instrumentation Laboratory Company Sealing systems

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Also Published As

Publication number Publication date
AU2012225810A1 (en) 2013-09-19
WO2012121998A1 (en) 2012-09-13
JP5844826B2 (ja) 2016-01-20
JP2014513276A (ja) 2014-05-29
EP2681554A1 (en) 2014-01-08
CN203203992U (zh) 2013-09-18
EP2681554B1 (en) 2017-08-09
CA2828761C (en) 2017-04-04
MX2013010168A (es) 2013-10-25
US9459187B2 (en) 2016-10-04
RU2623049C2 (ru) 2017-06-21
CN103477224B (zh) 2015-12-23
AU2012225810B2 (en) 2016-11-10
BR112013022662A2 (pt) 2017-06-27
ES2645022T3 (es) 2017-12-01
US20140030754A1 (en) 2014-01-30
RU2013144421A (ru) 2015-04-10
CA2828761A1 (en) 2012-09-13
MX347230B (es) 2017-04-20
ZA201306591B (en) 2018-12-19
CN103477224A (zh) 2013-12-25

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 02/03/2012, OBSERVADAS AS CONDICOES LEGAIS.