BR112013004419A2 - fungos filamentosos que têm um fenótipo de viscosidade alterada. - Google Patents

fungos filamentosos que têm um fenótipo de viscosidade alterada.

Info

Publication number
BR112013004419A2
BR112013004419A2 BR112013004419A BR112013004419A BR112013004419A2 BR 112013004419 A2 BR112013004419 A2 BR 112013004419A2 BR 112013004419 A BR112013004419 A BR 112013004419A BR 112013004419 A BR112013004419 A BR 112013004419A BR 112013004419 A2 BR112013004419 A2 BR 112013004419A2
Authority
BR
Brazil
Prior art keywords
filamentous fungi
phenotype
altered
altered viscosity
viscosity
Prior art date
Application number
BR112013004419A
Other languages
English (en)
Inventor
Aleksandra Virag
Michael Ward
Timothy C Dodge
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Publication of BR112013004419A2 publication Critical patent/BR112013004419A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2477—Hemicellulases not provided in a preceding group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01003—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

fungos filamentosos que têm um fenótipo de viscosidade alterada. a presente invenção refere-se a composições e métodos relacionando fungos filamentosos variantes com características de crescimento alteradas. tais variantes são bem adequadas para o crescimento em culturas submersas, por exemplo, para a produção em larga escala de enzimas e outras proteínas para aplicações comerciais.
BR112013004419A 2010-08-25 2011-08-25 fungos filamentosos que têm um fenótipo de viscosidade alterada. BR112013004419A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37703010P 2010-08-25 2010-08-25
PCT/US2011/049164 WO2012027580A1 (en) 2010-08-25 2011-08-25 Filamentous fungi having an altered viscosity phenotype

Publications (1)

Publication Number Publication Date
BR112013004419A2 true BR112013004419A2 (pt) 2016-05-31

Family

ID=44720107

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013004419A BR112013004419A2 (pt) 2010-08-25 2011-08-25 fungos filamentosos que têm um fenótipo de viscosidade alterada.

Country Status (14)

Country Link
US (1) US10266832B2 (pt)
EP (1) EP2609200B1 (pt)
JP (1) JP5707494B2 (pt)
KR (1) KR102004003B1 (pt)
CN (1) CN103097536B (pt)
AU (1) AU2011293263B2 (pt)
BR (1) BR112013004419A2 (pt)
CA (1) CA2808777C (pt)
DK (1) DK2609200T3 (pt)
MX (1) MX346558B (pt)
MY (1) MY160960A (pt)
RU (1) RU2608639C2 (pt)
WO (1) WO2012027580A1 (pt)
ZA (1) ZA201208720B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103517981B (zh) 2011-04-22 2017-02-15 丹尼斯科美国公司 具有粘度改变表型的丝状真菌
US9725727B2 (en) * 2011-04-22 2017-08-08 Danisco Us Inc Filamentous fungi having an altered viscosity phenotype
DK2918682T3 (da) * 2012-11-09 2019-06-03 Univ Tohoku Fremgangsmåde til fremstilling af nyttigt stof, hvor højdensitet-dyrket filamentøs svampestamme anvendes
JP6319515B2 (ja) * 2016-03-31 2018-05-09 東レ株式会社 タンパク質の製造方法
JP7376505B2 (ja) 2018-04-24 2023-11-08 ダニスコ・ユーエス・インク 粘性が低下した表現型を含む糸状菌株
US20210222221A1 (en) * 2018-07-30 2021-07-22 Toray Industries, Inc. Mutant of trichoderma filamentous fungus and method for producing protein
JP2021532775A (ja) 2018-07-30 2021-12-02 ダニスコ・ユーエス・インク タンパク質生産性が強化された表現型を含む突然変異及び遺伝子改変糸状菌株並びにそれらの方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5246853A (en) 1990-10-05 1993-09-21 Genencor International, Inc. Method for treating cotton-containing fabric with a cellulase composition containing endoglucanase components and which composition is free of exo-cellobiohydrolase I
US5861271A (en) 1993-12-17 1999-01-19 Fowler; Timothy Cellulase enzymes and systems for their expressions
US7504490B1 (en) 1998-10-16 2009-03-17 Oscient Pharmaceuticals Corporation Nucleic acid and amino acid sequences relating to Apergillus fumigatus for diagnostics and therapeutics
RU2238974C2 (ru) * 2001-09-06 2004-10-27 ООО НПК "Фермтек" Фрагмент днк мицелиального гриба penicillium verruculosum, кодирующий синтез секретируемой эндоглюканазы iii и группа штаммов penicillium canescens, синтезирующих эндоглюканазу iii penicillium verruculosum, сконструированных методами трансформации и генетической инженерии на основе этого фрагмента днк
CN1688198A (zh) * 2002-09-10 2005-10-26 金克克国际有限公司 使用高浓度糖混合物诱导基因表达
CN101857867A (zh) 2003-11-06 2010-10-13 金克克国际有限公司 蛋白酶抑制剂及其变异体在丝状真菌中的表达
US7413887B2 (en) * 2004-05-27 2008-08-19 Genecor International, Inc. Trichoderma reesei glucoamylase and homologs thereof
WO2007147263A1 (en) * 2006-06-22 2007-12-27 Iogen Energy Corporation Enzyme compositions and methods for the improved enzymatic hydrolysis of cellulose
CN101680019A (zh) 2007-06-15 2010-03-24 丹尼斯科美国公司 有用的真菌菌株的选择
CA2698765A1 (en) * 2007-09-07 2009-03-19 Danisco Us Inc. Beta-glucosidase enhanced filamentous fungal whole cellulase compositions and methods of use
CN102791853B (zh) 2009-09-23 2015-08-12 丹尼斯科美国公司 新型糖基水解酶及其用途

Also Published As

Publication number Publication date
JP5707494B2 (ja) 2015-04-30
AU2011293263A1 (en) 2012-12-06
CA2808777C (en) 2019-10-29
CA2808777A1 (en) 2012-03-01
MX2013002087A (es) 2013-05-09
CN103097536B (zh) 2016-01-13
CN103097536A (zh) 2013-05-08
ZA201208720B (en) 2014-01-29
DK2609200T3 (en) 2017-08-14
WO2012027580A1 (en) 2012-03-01
US20130224864A1 (en) 2013-08-29
US10266832B2 (en) 2019-04-23
RU2608639C2 (ru) 2017-01-23
KR102004003B1 (ko) 2019-07-25
RU2013112888A (ru) 2014-09-27
KR20130100108A (ko) 2013-09-09
AU2011293263B2 (en) 2014-10-23
MX346558B (es) 2017-03-24
EP2609200A1 (en) 2013-07-03
EP2609200B1 (en) 2017-04-26
MY160960A (en) 2017-03-31
JP2013533751A (ja) 2013-08-29

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
B11T Dismissal: dismissal of application maintained