BR112013000340A2 - anticorpo isolado que se liga a neuropilina-1 (nrp1), ácido nucleico isolado, célula hospedeira, método de produção de um anticorpo, imunoconjugado e método de detecção da presença de nrp1 em uma amostra biológica - Google Patents

anticorpo isolado que se liga a neuropilina-1 (nrp1), ácido nucleico isolado, célula hospedeira, método de produção de um anticorpo, imunoconjugado e método de detecção da presença de nrp1 em uma amostra biológica

Info

Publication number
BR112013000340A2
BR112013000340A2 BR112013000340A BR112013000340A BR112013000340A2 BR 112013000340 A2 BR112013000340 A2 BR 112013000340A2 BR 112013000340 A BR112013000340 A BR 112013000340A BR 112013000340 A BR112013000340 A BR 112013000340A BR 112013000340 A2 BR112013000340 A2 BR 112013000340A2
Authority
BR
Brazil
Prior art keywords
nrp1
antibody
isolated
neuropillin
immunoconjugate
Prior art date
Application number
BR112013000340A
Other languages
English (en)
Portuguese (pt)
Inventor
Chris Callahan
Hartmut Koeppen
Jo-Anne S Hongo
Maike Schmidt
Ryan J Watts
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BR112013000340A2 publication Critical patent/BR112013000340A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BR112013000340A 2010-07-09 2011-07-08 anticorpo isolado que se liga a neuropilina-1 (nrp1), ácido nucleico isolado, célula hospedeira, método de produção de um anticorpo, imunoconjugado e método de detecção da presença de nrp1 em uma amostra biológica BR112013000340A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36312110P 2010-07-09 2010-07-09
PCT/US2011/043318 WO2012006503A1 (en) 2010-07-09 2011-07-08 Anti-neuropilin antibodies and methods of use

Publications (1)

Publication Number Publication Date
BR112013000340A2 true BR112013000340A2 (pt) 2016-05-31

Family

ID=44628386

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013000340A BR112013000340A2 (pt) 2010-07-09 2011-07-08 anticorpo isolado que se liga a neuropilina-1 (nrp1), ácido nucleico isolado, célula hospedeira, método de produção de um anticorpo, imunoconjugado e método de detecção da presença de nrp1 em uma amostra biológica

Country Status (14)

Country Link
US (1) US8993249B2 (https=)
EP (1) EP2591004A1 (https=)
JP (1) JP2013539962A (https=)
KR (1) KR20130120439A (https=)
CN (1) CN103097418A (https=)
AU (1) AU2011274528B2 (https=)
BR (1) BR112013000340A2 (https=)
CA (1) CA2803792A1 (https=)
MX (1) MX2013000083A (https=)
NZ (1) NZ605449A (https=)
RU (1) RU2571226C2 (https=)
SG (1) SG186983A1 (https=)
WO (1) WO2012006503A1 (https=)
ZA (1) ZA201300174B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2013329372B2 (en) * 2012-10-08 2018-07-12 St. Jude Children's Research Hospital Therapies based on control of regulatory T cell stability and function via a Neuropilin-1:Semaphorin axis
CN107108743B (zh) * 2014-12-03 2021-05-04 (株)爱恩德生物 结合神经毡蛋白1的抗体及其用途
CN105237637B (zh) * 2015-11-10 2018-10-30 厦门大学 抗人神经纤毛蛋白1的单域抗体及其制备方法
PT3417073T (pt) 2016-02-19 2023-10-26 Procella Therapeutics Ab Marcadores genéticos para enxerto de células progenitoras ventriculares cardíacas humanas
KR101985299B1 (ko) * 2016-06-03 2019-09-03 삼성전자주식회사 항-c-Met/항-Nrp1 이중 특이 항체
US10508263B2 (en) 2016-11-29 2019-12-17 Procella Therapeutics Ab Methods for isolating human cardiac ventricular progenitor cells
JOP20190134A1 (ar) * 2016-12-23 2019-06-02 Potenza Therapeutics Inc بروتينات رابطة لمولد ضد مضادة لنيوروبيلين وطرق استخدامها
WO2019038587A1 (en) 2017-08-23 2019-02-28 Procella Therapeutics Ab USE OF NEUROPILIN-1 (NRP1) AS A CELL SURFACE MARKER FOR ISOLATING HUMAN CARDIAC VENTRICULAR PROGENITOR CELLS
WO2022117572A2 (en) 2020-12-02 2022-06-09 Oncurious Nv An ltbr agonist in combination therapy against cancer

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Also Published As

Publication number Publication date
ZA201300174B (en) 2014-03-26
KR20130120439A (ko) 2013-11-04
SG186983A1 (en) 2013-02-28
US8993249B2 (en) 2015-03-31
US20130115626A1 (en) 2013-05-09
AU2011274528B2 (en) 2015-04-23
RU2571226C2 (ru) 2015-12-20
EP2591004A1 (en) 2013-05-15
WO2012006503A1 (en) 2012-01-12
NZ605449A (en) 2015-03-27
RU2013105487A (ru) 2014-08-20
CA2803792A1 (en) 2012-01-12
CN103097418A (zh) 2013-05-08
AU2011274528A1 (en) 2013-01-24
JP2013539962A (ja) 2013-10-31
MX2013000083A (es) 2013-02-26

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