BR112013000097B1 - Polipeptídeo imunogênico isolado, composição imunogênica e seu uso - Google Patents

Polipeptídeo imunogênico isolado, composição imunogênica e seu uso Download PDF

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Publication number
BR112013000097B1
BR112013000097B1 BR112013000097-0A BR112013000097A BR112013000097B1 BR 112013000097 B1 BR112013000097 B1 BR 112013000097B1 BR 112013000097 A BR112013000097 A BR 112013000097A BR 112013000097 B1 BR112013000097 B1 BR 112013000097B1
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BR
Brazil
Prior art keywords
protein
spa
staphylococcal
binding
domain
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BR112013000097-0A
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English (en)
Portuguese (pt)
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BR112013000097A2 (pt
Inventor
Olaf Schneewind
Alice G. Cheng
Dominique M. Missiakas
Hwan Kim
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The University Of Chicago
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Publication of BR112013000097A2 publication Critical patent/BR112013000097A2/pt
Publication of BR112013000097B1 publication Critical patent/BR112013000097B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BR112013000097-0A 2010-07-02 2011-07-01 Polipeptídeo imunogênico isolado, composição imunogênica e seu uso BR112013000097B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US36121810P 2010-07-02 2010-07-02
US61/361,218 2010-07-02
US37072510P 2010-08-04 2010-08-04
US61/370,725 2010-08-04
PCT/US2011/042845 WO2012003474A2 (en) 2010-07-02 2011-07-01 Compositions and methods related to protein a (spa) variants

Publications (2)

Publication Number Publication Date
BR112013000097A2 BR112013000097A2 (pt) 2017-05-16
BR112013000097B1 true BR112013000097B1 (pt) 2022-02-01

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BR112013000097-0A BR112013000097B1 (pt) 2010-07-02 2011-07-01 Polipeptídeo imunogênico isolado, composição imunogênica e seu uso

Country Status (12)

Country Link
US (8) US8821894B2 (enExample)
EP (1) EP2588120B1 (enExample)
JP (1) JP6002128B2 (enExample)
KR (1) KR20130093084A (enExample)
CN (1) CN103037885B (enExample)
AU (1) AU2011274367B2 (enExample)
BR (1) BR112013000097B1 (enExample)
CA (1) CA2803298C (enExample)
ES (1) ES2655701T3 (enExample)
SG (1) SG186290A1 (enExample)
WO (1) WO2012003474A2 (enExample)
ZA (1) ZA201209561B (enExample)

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CA2803298C (en) * 2010-07-02 2020-07-14 The University Of Chicago Compositions and methods related to protein a (spa) variants
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EP2614074A1 (en) * 2010-09-09 2013-07-17 The University of Chicago Methods and compositions involving protective staphylococcal antigens
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TWI709571B (zh) * 2015-03-26 2020-11-11 日商Ｊｓｒ股份有限公司 免疫球蛋白結合蛋白質及使用此之親和性載體
JP7117244B2 (ja) * 2016-02-12 2022-08-12 ザ・ユニバーシティ・オブ・シカゴ 黄色ブドウ球菌疾患の間にコアグラーゼ活性を中和する抗体に関連した組成物および方法
US10738338B2 (en) 2016-10-18 2020-08-11 The Research Foundation for the State University Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
JP7355729B2 (ja) 2017-08-07 2023-10-03 レプリゲン・コーポレイション Ｃ末端ヘリカル領域にシステインを有するｆｃ結合タンパク質
EP4249097A3 (en) * 2018-02-01 2024-01-10 Repligen Corporation Fc binding proteins with cysteine in the c-terminal helical region
GB201802339D0 (en) * 2018-02-13 2018-03-28 Glaxosmithkline Biologicals Sa Immunogenic composition
US20220323563A1 (en) * 2019-05-14 2022-10-13 The University Of Chicago Methods and compositions comprising staphylococcus protein a (spa) variants
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IL291821A (en) * 2019-10-02 2022-06-01 Janssen Vaccines & Prevention Bv Staphylococcus peptides and methods of use
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