BR112012027170A2 - processo para a preparação de cloretos e fluoretos de 5-fluoro-1-alquil-3-fluoroalquil-1h-pirazol-4-carbonila. - Google Patents

processo para a preparação de cloretos e fluoretos de 5-fluoro-1-alquil-3-fluoroalquil-1h-pirazol-4-carbonila.

Info

Publication number
BR112012027170A2
BR112012027170A2 BR112012027170A BR112012027170A BR112012027170A2 BR 112012027170 A2 BR112012027170 A2 BR 112012027170A2 BR 112012027170 A BR112012027170 A BR 112012027170A BR 112012027170 A BR112012027170 A BR 112012027170A BR 112012027170 A2 BR112012027170 A2 BR 112012027170A2
Authority
BR
Brazil
Prior art keywords
pyrazol
fluoro
fluoroalkyl
alkyl
fluorides
Prior art date
Application number
BR112012027170A
Other languages
English (en)
Other versions
BR112012027170B1 (pt
Inventor
Norbert Lui
Sergii Pazenok
Stephanie Gary
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of BR112012027170A2 publication Critical patent/BR112012027170A2/pt
Publication of BR112012027170B1 publication Critical patent/BR112012027170B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

processo para a preparação de cloreto e fluoretos de 5-fluoro-1-alquil-3-fluoroalquil-1h-pirazol-4-carbonila. a presente invenção se refere a um novo processo paraa preparação de haletos de 5-fluoro-1-alquil-3-fluoroalquil-1h-pirazol-4-carbonila e dos intermediários que ocorrem neste processo, 5-cloro-1-metil-3-difluorometil-1h-pirazol-4-carboxilato de etila e 5-fluoro-1-metil-3-difluorometil-1h-pirazol-4-carboxilato de etila.
BR112012027170-9A 2010-04-23 2011-04-18 Processo para a preparação de cloretos e fluoretos de 5-fluoro-1-alquil-3-fluoroalquil-1h- pirazol-4-carbonila, bem como compostos intermediários dos mesmos BR112012027170B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US32726910P 2010-04-23 2010-04-23
EP10160885.9 2010-04-23
EP10160885 2010-04-23
US61/327,269 2010-04-23
PCT/EP2011/056119 WO2011131615A1 (de) 2010-04-23 2011-04-18 Verfahren zum herstellen von 5-fluor-1-alkyl-3-fluoralkyl-1h-pyrazol-4-carbonsäurechloriden und -fluoriden

Publications (2)

Publication Number Publication Date
BR112012027170A2 true BR112012027170A2 (pt) 2015-09-15
BR112012027170B1 BR112012027170B1 (pt) 2018-02-14

Family

ID=42836944

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012027170-9A BR112012027170B1 (pt) 2010-04-23 2011-04-18 Processo para a preparação de cloretos e fluoretos de 5-fluoro-1-alquil-3-fluoroalquil-1h- pirazol-4-carbonila, bem como compostos intermediários dos mesmos

Country Status (12)

Country Link
US (1) US8431718B2 (pt)
EP (1) EP2560961B1 (pt)
JP (1) JP5819938B2 (pt)
KR (1) KR101774966B1 (pt)
CN (1) CN103140477B (pt)
BR (1) BR112012027170B1 (pt)
DK (1) DK2560961T3 (pt)
ES (1) ES2616005T3 (pt)
IL (1) IL222627A (pt)
MX (1) MX2012012085A (pt)
TW (1) TWI560181B (pt)
WO (1) WO2011131615A1 (pt)

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AR076839A1 (es) * 2009-05-15 2011-07-13 Bayer Cropscience Ag Derivados fungicidas de pirazol carboxamidas
MX2015001756A (es) * 2012-08-07 2015-06-05 Bayer Cropscience Ag Procedimiento para la preparacion de pirazolcarboxilatos que contienen perfluoroalquilos.
KR102261967B1 (ko) * 2013-01-17 2021-06-07 바이엘 크롭사이언스 악티엔게젤샤프트 5-플루오로-1-메틸-3-디플루오로메틸-1h-피라졸-4-카브알데히드 제조 방법
DK2953942T3 (en) 2013-02-06 2018-01-22 Bayer Cropscience Ag HALOGEN-SUBSTITUTED PYRAZOLD DERIVATIVES AS PESTICIDES.
MX2016003253A (es) * 2013-09-20 2016-06-07 Bayer Cropscience Ag Proceso para la preparacion del 5-fluoro-1-alquil-3-fluoroalquil-1 h-pirazol-4-carbaldehido.
BR112016017527B1 (pt) 2014-01-03 2021-01-05 Bayer Animal Health Gmbh compostos, usos de compostos, composições farmacêuticas, processo para produzir composições e método não terapêutico para controlar pragas
BR112016016397B1 (pt) * 2014-01-24 2021-06-29 Bayer Cropscience Aktiengesellschaft Processo para preparar 1-alquil-3-difluorometil-5- fluoro-1h-pirazol-4-carbaldeídos ou os seus ésteres
TWI705055B (zh) 2015-04-29 2020-09-21 德商拜耳作物科學公司 製備5-氟-1h-吡唑-4-羰基氟化物之方法
CN106380447B (zh) * 2016-08-29 2019-09-13 联化科技（台州）有限公司 3-二氟甲基-1-甲基-1h-吡唑-4-甲酸及其中间体的制备方法及中间体
CN112174891B (zh) * 2020-11-02 2022-02-01 浙江省农业科学院 一种氟唑菌苯胺代谢物的制备方法
WO2022233129A1 (en) * 2021-05-05 2022-11-10 Fujian Yongjing Technology Co., Ltd New process for the synthesis of 5-fluoro-3- (difuoromethyl) -5-fluoro-1-methyl-1h-pyrazole-4-carboxylic acid derivatives and the free acid thereof
JP2023539392A (ja) * 2021-05-05 2023-09-14 福建永晶科技股▲ふん▼有限公司 ５－フルオロ－３－（ジフルオロメチル）－５－フルオロ－１－メチル－１ｈ－ピラゾール－４－カルボン酸誘導体及びその遊離酸を合成する方法

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JPH0285257A (ja) * 1988-09-21 1990-03-26 Sumitomo Chem Co Ltd 置換ピラゾール−４−カルボン酸クロリドの製造法
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JPH0543553A (ja) * 1991-08-14 1993-02-23 Nissan Chem Ind Ltd ３，５−ジクロロピラゾール−４−カルボン酸エステル類の製造方法
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JPH0710845A (ja) * 1993-06-24 1995-01-13 Sumitomo Chem Co Ltd ５−クロロピラゾール−４−カルボニルクロリド類の製造方法
BR9606610A (pt) * 1995-08-31 1997-10-14 Dowelanco Herbicidas n-(1-etil-4-pirazolil) triazolazinasulfonamida
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EP2325173A1 (de) 2009-11-19 2011-05-25 Bayer CropScience AG Verfahren zum Herstellen von 5-Fluor-1-alkyl-3-fluoralkyl-1H-pyrazol-4-carbonsäurechloriden

Also Published As

Publication number Publication date
KR101774966B1 (ko) 2017-09-05
BR112012027170B1 (pt) 2018-02-14
CN103140477A (zh) 2013-06-05
CN103140477B (zh) 2015-07-15
TWI560181B (en) 2016-12-01
DK2560961T3 (en) 2017-02-20
JP5819938B2 (ja) 2015-11-24
EP2560961A1 (de) 2013-02-27
US20110288305A1 (en) 2011-11-24
US8431718B2 (en) 2013-04-30
TW201206890A (en) 2012-02-16
IL222627A (en) 2014-09-30
EP2560961B1 (de) 2016-11-16
WO2011131615A1 (de) 2011-10-27
ES2616005T3 (es) 2017-06-09
MX2012012085A (es) 2012-11-29
KR20130052570A (ko) 2013-05-22
JP2013525324A (ja) 2013-06-20

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B25G Requested change of headquarter approved
B25A Requested transfer of rights approved