BR112012016119B1 - método de detecção de células em uma amostra, dispositivo unitário de preparação e detecção de amostra e kit - Google Patents

método de detecção de células em uma amostra, dispositivo unitário de preparação e detecção de amostra e kit Download PDF

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Publication number
BR112012016119B1
BR112012016119B1 BR112012016119A BR112012016119A BR112012016119B1 BR 112012016119 B1 BR112012016119 B1 BR 112012016119B1 BR 112012016119 A BR112012016119 A BR 112012016119A BR 112012016119 A BR112012016119 A BR 112012016119A BR 112012016119 B1 BR112012016119 B1 BR 112012016119B1
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BR
Brazil
Prior art keywords
sample
kit
sample preparation
detection device
detection method
Prior art date
Application number
BR112012016119A
Other languages
English (en)
Portuguese (pt)
Other versions
BR112012016119A2 (pt
Inventor
E Aysta James
J Halverson Kurt
T Kshirsagar Manjiri
Rajagopal Raj
Original Assignee
3M Innovative Properties Co
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Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of BR112012016119A2 publication Critical patent/BR112012016119A2/pt
Publication of BR112012016119B1 publication Critical patent/BR112012016119B1/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/042—Caps; Plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0672—Integrated piercing tool
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B01L2400/0683—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021—Test tubes specially adapted for centrifugation purposes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5029—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures using swabs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Clinical Laboratory Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BR112012016119A 2009-12-30 2010-12-30 método de detecção de células em uma amostra, dispositivo unitário de preparação e detecção de amostra e kit BR112012016119B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29130109P 2009-12-30 2009-12-30
US33193110P 2010-05-06 2010-05-06
PCT/US2010/062517 WO2011082309A1 (en) 2009-12-30 2010-12-30 Live bioload detection using microparticles

Publications (2)

Publication Number Publication Date
BR112012016119A2 BR112012016119A2 (pt) 2016-05-31
BR112012016119B1 true BR112012016119B1 (pt) 2020-04-28

Family

ID=43639978

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012016119A BR112012016119B1 (pt) 2009-12-30 2010-12-30 método de detecção de células em uma amostra, dispositivo unitário de preparação e detecção de amostra e kit

Country Status (6)

Country Link
US (1) US9284593B2 (enExample)
EP (1) EP2519355B1 (enExample)
JP (1) JP5972174B2 (enExample)
CN (1) CN102770208B (enExample)
BR (1) BR112012016119B1 (enExample)
WO (1) WO2011082309A1 (enExample)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010078399A2 (en) 2008-12-31 2010-07-08 3M Innovative Properties Company Sampling devices and methods for concentrating microorganisms
CN102325596B (zh) 2008-12-31 2015-04-29 3M创新有限公司 使用微粒进行的活生物负载检测
CN102686995A (zh) * 2009-12-22 2012-09-19 3M创新有限公司 微生物浓集方法以及用于其中的浓集剂
EP2658991B1 (en) 2010-12-31 2018-10-10 3M Innovative Properties Company Effervescent compositions and uses thereof
ITUD20110129A1 (it) * 2011-08-10 2013-02-11 Alifax Holding S P A Dispositivo per la raccolta di campioni biologici, e relativo procedimento
US9382569B1 (en) 2012-01-17 2016-07-05 Elemental Scientific, Inc. Fast detection of the presence of a target microbe in a liquid sample
WO2013113072A1 (en) 2012-02-03 2013-08-08 Axxin Pty Ltd Nucleic acid amplification and detection apparatus and method
EP2870257B1 (en) * 2012-07-06 2017-02-22 3M Innovative Properties Company Apparatus and methods for detecting atp in a liquid sample
JP2015532114A (ja) * 2012-10-20 2015-11-09 セルフダイアグノスティックス オーウー 生物学的サンプル及び体液に由来する核酸標的の検出のための方法及びその組成物
KR200488464Y1 (ko) * 2012-12-27 2019-02-07 피티티 글로벌 케미칼 피씨엘 혼합물 또는 용액의 제조 및 전달 장치
CN112782393B (zh) 2013-03-11 2024-11-19 克忧健康公司 用于检测和量化分析物的系统和方法
US10545161B2 (en) 2013-03-11 2020-01-28 Cue Health Inc. Systems and methods for detection and quantification of analytes
US9623409B2 (en) 2013-03-11 2017-04-18 Cue Inc. Cartridges, kits, and methods for enhanced mixing for detection and quantification of analytes
KR101390920B1 (ko) 2013-12-13 2014-04-30 김준우 지방파쇄기 및 지방파쇄가 가능한 성분분리기
USD745423S1 (en) 2014-05-12 2015-12-15 Cue Inc. Automated analyzer test cartridge and sample collection device for analyte detection
US11299702B2 (en) * 2015-04-17 2022-04-12 Vax-Immune, LLC Portable disposable re-usable culture device for rapid diagnosis of infectious agents
EP3283640B1 (en) * 2015-04-17 2021-03-03 Vax-Immune LLC Portable disposable re-usable culture device for rapid diagnosis of infectious agents
US9994808B2 (en) * 2015-04-17 2018-06-12 Vax-Immune, LLC Portable disposable re-usable culture device for rapid diagnosis of infectious agents
EP3325153B1 (en) 2015-07-17 2020-03-18 Cue Health Inc. Sample analysis cartridge
CN106179552B (zh) * 2016-07-06 2018-09-11 江苏科华医疗器械科技有限公司 一种一体式超滤离心管
US11491478B2 (en) * 2016-08-22 2022-11-08 Universal Bio Research Co., Ltd. Dispensing cylinder, and dispensing device and dispensing treatment method using same
CA3045457A1 (en) * 2016-12-01 2018-06-07 Novel Microdevices, Llc Automated point-of-care devices for complex sample processing and methods of use thereof
JP6699837B2 (ja) * 2016-12-27 2020-05-27 株式会社フルステム ３次元多孔性足場からの培養細胞回収方法
US10537892B2 (en) * 2017-01-03 2020-01-21 Illumina, Inc. Sample tube with integrated mixing plunger head
US11237161B2 (en) 2017-01-25 2022-02-01 Cue Health Inc. Systems and methods for enhanced detection and quantification of analytes
KR102061651B1 (ko) * 2017-03-03 2020-01-02 사회복지법인 삼성생명공익재단 검체의 전처리 장치 및 이에 의한 검체의 전처리 방법
US10704993B2 (en) * 2017-06-06 2020-07-07 United States Of America As Represented By The Secretary Of The Department Of The Interior Subsurface environment sampler with actuator movable collection chamber
US11090646B2 (en) 2017-07-27 2021-08-17 Biomerieux, Inc. Isolation tube
WO2019060950A1 (en) * 2017-09-27 2019-04-04 Axxin Pty Ltd SYSTEM AND METHOD FOR DIAGNOSTIC TESTING
JP6680742B2 (ja) * 2017-10-31 2020-04-15 大研医器株式会社 磁性粒子収集方法及び試験セット
KR102005366B1 (ko) * 2017-12-19 2019-07-30 한국과학기술원 다공성 복합 나노구조체를 이용한 바이오물질의 포집 및 진단 시스템 및 방법
CN108267496B (zh) * 2017-12-22 2020-06-05 江南大学 一种利用电化学检测活性成分缓释效果的方法
CN108796038B (zh) * 2018-06-26 2019-10-18 杭州优思达生物技术有限公司 一种核酸一体化检测方法及检测试剂管
KR102136695B1 (ko) * 2018-08-22 2020-07-22 주식회사 인퓨전텍 현장 진단용 장치를 이용한 병원체 농축 및 핵산 추출 방법
WO2020077286A1 (en) * 2018-10-12 2020-04-16 Quidel Corporation Extraction reagent for use in an assay for detection of group a streptococcus
CN111175481B (zh) * 2018-11-09 2025-03-04 广州万孚生物技术股份有限公司 血气生化测试卡、血气分析仪及血气分析仪的控制方法
CA3125901A1 (en) * 2019-01-07 2020-07-16 1866402 Ontario Limited Blood separation and analysis device and methods
TWI683702B (zh) * 2019-01-31 2020-02-01 瑩芳有限公司 採檢容器
KR102788544B1 (ko) * 2019-04-16 2025-03-31 (주)얼라인드제네틱스 애널라이트 수집 장치, 이를 이용한 애널라이트 수집 방법 및 애널라이트 검사 시스템
US20220297115A1 (en) * 2019-10-29 2022-09-22 Hewlett-Packard Development Company, L.P. Fluid preparation devices
GB202003403D0 (en) * 2020-03-09 2020-04-22 Oribiotech Ltd A system for cell processing
EP4212845B1 (en) * 2020-09-11 2025-11-19 FUJIFILM Corporation Concentration device, liquid specimen concentration method, liquid specimen inspection method, and inspection kit
JP7686786B2 (ja) 2021-12-06 2025-06-02 旭化成株式会社 微生物の濃縮方法及び濃縮容器
USD1045122S1 (en) 2022-06-28 2024-10-01 Vax-Immune, LLC Sample incubation and testing device
USD1045121S1 (en) 2022-06-28 2024-10-01 Vax-Immune, LLC Sample incubation and testing device
USD1069156S1 (en) 2023-04-10 2025-04-01 Becton, Dickinson And Company Dispensing device

Family Cites Families (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL109202C (enExample) 1959-11-20
GB1085901A (en) 1964-01-15 1967-10-04 Courtaulds Ltd Fermentation apparatus
US3933592A (en) 1965-02-17 1976-01-20 Hazleton Laboratories, Incorporated Method of detecting living microorganisms
US3745090A (en) 1970-08-04 1973-07-10 Nasa Method of detecting and counting bacteria in body fluids
US4184483A (en) * 1973-05-08 1980-01-22 U.S. Medical Research & Development, Inc. Method of and apparatus for collecting cultures
US3897902A (en) 1974-02-01 1975-08-05 Sindco Corp Phase separating tube
US3971703A (en) 1974-05-31 1976-07-27 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Method of detecting and counting bacteria
US4144134A (en) 1977-01-31 1979-03-13 Vitatect Corp. Method for detection of bacterial concentration by luminescence
GB1604249A (en) 1977-05-31 1981-12-02 Kolehmainen S Selective measurement of somatic and microbial cells
GB2073885B (en) 1980-04-15 1983-12-21 Whitlock G D Method of and apparatus for detecting the presence of live organisms in substances
GB2138021B (en) 1983-03-29 1987-02-04 Polythene Drums Yeast fermentation
US4503149A (en) 1983-06-06 1985-03-05 Conoco Inc. Method of microbial assay
US4698311A (en) 1985-10-30 1987-10-06 Ortho Diagnostic Systems Inc. Particle washing and separation method
JPS62167221A (ja) 1986-01-17 1987-07-23 Showa Denko Kk レピッドクロサイトの製造方法
US4906565A (en) 1986-03-21 1990-03-06 Minnesota Mining And Manufacturing Company Method for the selective detection of microbial nucleotides
US5238812A (en) 1987-03-13 1993-08-24 Coulter Corporation Method and apparatus for rapid mixing of small volumes for enhancing biological reactions
DK258787D0 (da) 1987-05-21 1987-05-21 Foss Electric As N Fremgangsmaade til bestemmelse af bakteriekoncentration i en proeve
US4978504A (en) * 1988-02-09 1990-12-18 Nason Frederic L Specimen test unit
CA1339250C (en) 1988-03-21 1997-08-12 Richard Calvin Ebersole Method and apparatus for collecting and detecting microorganisms
DE69126620T2 (de) 1990-10-18 1997-10-02 Cellpro Inc Vorrichtung und verfahren zur trennung von partikeln mittels eines biegsamen gefässes
US5264184A (en) 1991-03-19 1993-11-23 Minnesota Mining And Manufacturing Company Device and a method for separating liquid samples
JP3168755B2 (ja) 1993-02-22 2001-05-21 株式会社明電舎 生物固定化担体中の微生物量測定方法
US5576185A (en) 1994-04-15 1996-11-19 Coulter Corporation Method of positive or negative selection of a population or subpopulation of a sample utilizing particles and gravity sedimentation
US5595653A (en) 1994-07-15 1997-01-21 Cera, Inc. Microcolumn for extraction of analytes from liquids
GB9417793D0 (en) 1994-09-05 1994-10-26 Celsis Ltd Bioluminescence and assay reagents
DE19524753A1 (de) 1995-07-07 1997-01-23 Lohmann Therapie Syst Lts Schichttablette zur kontrollierten Freisetzung von Wirkstoffen
DE69629582T2 (de) 1995-07-12 2004-06-24 Charm Sciences, Inc., Lawrence Testvorrichtung, sytem und verfahren zum nachweis von testproben
US5827675A (en) * 1995-07-12 1998-10-27 Charm Sciences, Inc. Test apparatus, system and method for the detection of test samples
US6140040A (en) 1995-10-06 2000-10-31 Advanced Minerals Corporation Method of mechanically separating microparticles suspended in fluids using particulate media
US6045913A (en) 1995-11-01 2000-04-04 Minnesota Mining And Manufacturing Company At least partly fused particulates and methods of making them by flame fusion
JP3547882B2 (ja) 1995-12-28 2004-07-28 キッコーマン株式会社 Ａｔｐ消去剤、ａｔｐ消去法、それを用いた生物細胞測定試薬及び生物細胞測定法
US5908751A (en) 1996-04-26 1999-06-01 Toyo Ink Mfg. Co., Ltd. Method for detecting and/or determining ATP from microorganism cells in a sample
US5905029A (en) 1997-02-19 1999-05-18 Fritz Berthold Method for rapid hygiene testing
JPH1128099A (ja) 1997-05-12 1999-02-02 Kikkoman Corp 黄色ブドウ球菌の検出法
US6451260B1 (en) 1997-08-26 2002-09-17 Dyax Corp. Method for producing microporous elements, the microporous elements thus produced and uses thereof
US6861067B2 (en) 1998-09-17 2005-03-01 Sherwood Services Ag Hydrogel wound dressing and the method of making and using the same
EP1131159A1 (en) 1998-11-18 2001-09-12 Orchid BioSciences, Inc. One-step nucleic acid dipstick device with movable membrane
DE19856064C2 (de) * 1998-12-04 2000-11-30 Invitek Gmbh Universelles Verfahren zur Isolierung von DNA aus beliebigen Ausgangsmaterialien
US6174704B1 (en) 1998-12-23 2001-01-16 Pierce Chemical Company Method for recovery of proteins prepared by recombinant DNA procedures
ES2367979T3 (es) 1999-05-25 2011-11-11 Millipore Corporation Procedimiento para detectar y enumerar microorganismos rápidamente en preparaciones de células de mamíferos usando la bioluminiscencia del atp.
US7223364B1 (en) 1999-07-07 2007-05-29 3M Innovative Properties Company Detection article having fluid control film
US7109315B2 (en) * 2000-03-15 2006-09-19 Bruce J. Bryan Renilla reniformis fluorescent proteins, nucleic acids encoding the fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items
US6660489B2 (en) 2000-12-01 2003-12-09 Becton, Dickinson And Company ATP extraction method
EP1845375A3 (en) 2000-12-22 2008-05-21 Bio A.R.T. BVBA Flow through assay device, diagnostic kit comprising said device and use in the detection of an analyte in a sample
US7083911B2 (en) 2001-02-16 2006-08-01 Promega Corporation Method for detection of ATP
US6824560B2 (en) 2001-06-13 2004-11-30 Advanced Cardiovascular Systems, Inc. Double-butted superelastic nitinol tubing
CN1514739A (zh) 2001-06-29 2004-07-21 具有气味控制性能的高吸水性含羧基聚合物和制备方法
US20050153423A1 (en) 2001-07-02 2005-07-14 Health Dynamics Institute Appliance for recovering solid component in liquid sample
US6588681B2 (en) 2001-07-09 2003-07-08 3M Innovative Properties Company Liquid supply assembly
US6967261B1 (en) 2001-12-28 2005-11-22 Kimberly-Clark Worldwide Bandage, methods of producing and using same
US7005143B2 (en) 2002-04-12 2006-02-28 3M Innovative Properties Company Gel materials, medical articles, and methods
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
AU2003243627A1 (en) 2002-06-18 2003-12-31 Ingersoll-Rand Energy Systems Corporation Microturbine engine system
US20040124085A1 (en) 2002-06-26 2004-07-01 California Institute Of Technology Microfluidic devices and methods with electrochemically actuated sample processing
US20040197845A1 (en) * 2002-08-30 2004-10-07 Arjang Hassibi Methods and apparatus for pathogen detection, identification and/or quantification
EP1603674B1 (en) 2003-02-05 2016-01-06 Iquum, Inc. Sample processing
JP4364562B2 (ja) 2003-06-19 2009-11-18 株式会社メガチップス 映像記録システムにおけるカメラ管理方法
TW200510724A (en) 2003-07-30 2005-03-16 Riken Kit for nucleic acid detection
EP1654389A2 (en) 2003-08-12 2006-05-10 Massachusetts Institute of Technology Sample preparation methods and devices
US7338692B2 (en) 2003-09-12 2008-03-04 3M Innovative Properties Company Microporous PVDF films
JP4378608B2 (ja) 2003-09-26 2009-12-09 Ｄｉｃ株式会社 土木建築材用被覆組成物、舗装材及びこれを用いた舗装体
US20050070701A1 (en) 2003-09-29 2005-03-31 Hochstetler Spencer Erich Detection of living cells in polymers or pigments
US20050142571A1 (en) * 2003-12-24 2005-06-30 3M Innovative Properties Company Methods for nucleic acid isolation and kits using solid phase material
US20050152992A1 (en) 2004-01-13 2005-07-14 Johnson Loyal M.Jr. Antimicrobial surface preparation and method for producing the same
EP1706037A1 (en) 2004-01-16 2006-10-04 Andx, Inc. Sample collection device and method
GB0401288D0 (en) * 2004-01-21 2004-02-25 Orion Diagnostica Oy Sampling and assay device
ITRM20040168A1 (it) 2004-04-01 2004-07-01 Sigma Tau Ind Farmaceuti Composizione a rilascio modificato ph dipendente.
US20050250138A1 (en) 2004-05-04 2005-11-10 Millipore Corporation Process for the enumeration and identification of microorganisms
CA2572608A1 (en) 2004-07-02 2006-08-17 Promega Corporation Microbial atp extraction and detection system
WO2006014410A1 (en) 2004-07-02 2006-02-09 Bayer Healthcare Llc Light guide test sensor for use in determining an analyte in a fluid sample and methods for manufacturing the same
US7282181B2 (en) 2004-09-16 2007-10-16 Varian Inc. Fluid collection and testing device
US20060062854A1 (en) 2004-09-22 2006-03-23 Noble Fiber Technologies, Llc Hydrogel having anti-microbial properties
US7993871B2 (en) * 2004-12-22 2011-08-09 Charm Sciences, Inc. Sampling method and device
EP1841854A4 (en) * 2005-01-27 2009-10-21 Applera Corp DEVICES AND METHODS FOR PREPARING SAMPLES
US7485609B2 (en) 2005-09-29 2009-02-03 Kimberly-Clark Worldwide, Inc. Encapsulated liquid cleanser
GB2433219A (en) 2005-12-16 2007-06-20 Diasys Europ Ltd A filtering device
US7824732B2 (en) 2005-12-28 2010-11-02 3M Innovative Properties Company Encapsulated chromonic particles
EP1968792B1 (en) 2005-12-30 2013-12-11 3M Innovative Properties Company Functionalized substrates
US20080023408A1 (en) 2006-01-13 2008-01-31 Vanson Halosource, Inc. Catch basin insert for treating storm water
GB0606822D0 (en) 2006-04-05 2006-05-17 Alaska Food Diagnostics Assay System
EP2024742B1 (en) 2006-05-22 2020-03-04 3M Innovative Properties Company System and method for preparing samples
US20070269341A1 (en) 2006-05-22 2007-11-22 3M Innovative Properties Company Sampling assembly and method of preparing samples
BRPI0712183A2 (pt) 2006-06-08 2012-01-17 3M Innovative Properties Co microesferas poliméricas e métodos de preparo de microesferas poliméricas
US20080153125A1 (en) 2006-11-10 2008-06-26 Advanced Analytical Technologies, Inc. Rapid detection of microorganisms in fluids
GB0625309D0 (en) 2006-12-19 2007-01-24 Inverness Medical Switzerland Device
US7939578B2 (en) 2007-02-23 2011-05-10 3M Innovative Properties Company Polymeric fibers and methods of making
WO2008122908A1 (en) 2007-04-04 2008-10-16 Koninklijke Philips Electronics N.V. Method and device for gathering a fluid sample for screening purposes
CN101663581A (zh) 2007-04-19 2010-03-03 3M创新有限公司 水分散性二氧化硅纳米颗粒在连接生物分子方面的用途
WO2008129517A2 (en) 2007-04-23 2008-10-30 Ranbaxy Laboratories Limited A stabilized delayed release pharmaceutical composition of rabeprazole
US20100062421A1 (en) 2007-04-25 2010-03-11 Wensheng Xia Compositions, methods, and devices for isolating biological materials
US20100297691A1 (en) 2007-05-31 2010-11-25 Ribeiro Alice Maria M Devices and processes for collecting and concentrating samples for microbiological analysis
US7829020B2 (en) 2007-08-02 2010-11-09 Lawrence Livermore National Laboratory, Llc Simple, field portable colorimetric detection device for organic peroxides and hydrogen peroxide
BRPI0817415B8 (pt) 2007-10-03 2021-07-27 3M Innovative Properties Co processo e kit para capturar ou concentrar microorganismos
WO2009046081A2 (en) 2007-10-03 2009-04-09 3M Innovative Properties Company Process for limiting the growth of microorganisms
BRPI0817602B1 (pt) 2007-10-03 2018-01-16 3M Innovative Properties Company Processo para capturar ou concentrar micro- organismos e kits de diagnóstico
EP2205717B1 (en) 2007-10-03 2017-08-16 3M Innovative Properties Company Microorganism concentration process
KR101408473B1 (ko) 2007-10-11 2014-06-17 쓰리엠 이노베이티브 프로퍼티즈 컴파니 평균 기공 크기가 비교적 큰 미세다공성 막 및 이를 제조하는 방법
US20100209927A1 (en) 2007-11-06 2010-08-19 Menon Vinod P Processing device tablet
CN101909755B (zh) 2007-11-20 2013-09-18 3M创新有限公司 样品制备容器和方法
US8685746B2 (en) 2007-11-20 2014-04-01 3M Innovative Properties Company Sample preparation container and method
US8563264B2 (en) 2007-11-20 2013-10-22 3M Innovative Properties Company Sample preparation for environmental sampling
EP2217378B1 (en) 2007-11-20 2013-02-13 3M Innovative Properties Company Sample preparation container and method
JP5676271B2 (ja) 2007-12-12 2015-02-25 スリーエム イノベイティブ プロパティズ カンパニー 成形された高分子材料の製造方法
WO2009082667A1 (en) 2007-12-21 2009-07-02 3M Innovative Properties Company Microbiological systems and methods of fluid sample analysis
CN101952301A (zh) 2008-02-14 2011-01-19 3M创新有限公司 用于微生物检测的多肽
CN101952729A (zh) * 2008-02-20 2011-01-19 3M创新有限公司 利用全细胞捕获和atp分析进行样品细菌分析的方法
GB0808557D0 (en) * 2008-05-13 2008-06-18 3M Innovative Properties Co Sampling devices and methods of use
US20110256531A1 (en) 2008-09-30 2011-10-20 3M Innovative Properties Company Biodetection articles
CN102325598A (zh) 2008-12-31 2012-01-18 3M创新有限公司 用于处理样品的方法、套件和系统
WO2010078399A2 (en) 2008-12-31 2010-07-08 3M Innovative Properties Company Sampling devices and methods for concentrating microorganisms
CN102325596B (zh) 2008-12-31 2015-04-29 3M创新有限公司 使用微粒进行的活生物负载检测
US20120082977A1 (en) 2009-05-06 2012-04-05 Raj Rajagopal Articles with matrix comprising a cell extractant and biodetection methods thereof
WO2010129727A1 (en) 2009-05-06 2010-11-11 3M Innovative Properties Company Coated substrates comprising a cell extractant and biodetection methods thereof
WO2010129728A2 (en) 2009-05-06 2010-11-11 3M Innovative Properties Company Articles with shell structures including a cell extractant and biodetection methods thereof
CN102686995A (zh) 2009-12-22 2012-09-19 3M创新有限公司 微生物浓集方法以及用于其中的浓集剂

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BR112012016119A2 (pt) 2016-05-31
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