BR112012013427A2 - circulação dos componentes durante a homogeneização de emulsões - Google Patents

circulação dos componentes durante a homogeneização de emulsões

Info

Publication number
BR112012013427A2
BR112012013427A2 BR112012013427A BR112012013427A BR112012013427A2 BR 112012013427 A2 BR112012013427 A2 BR 112012013427A2 BR 112012013427 A BR112012013427 A BR 112012013427A BR 112012013427 A BR112012013427 A BR 112012013427A BR 112012013427 A2 BR112012013427 A2 BR 112012013427A2
Authority
BR
Brazil
Prior art keywords
circulation
components during
during emulsion
emulsion
homogenization
Prior art date
Application number
BR112012013427A
Other languages
English (en)
Other versions
BR112012013427B8 (pt
BR112012013427B1 (pt
Inventor
Barbara Santry
Hanno Scheffczik
Harald Rueckl
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43923723&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112012013427(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR112012013427A2 publication Critical patent/BR112012013427A2/pt
Publication of BR112012013427B1 publication Critical patent/BR112012013427B1/pt
Publication of BR112012013427B8 publication Critical patent/BR112012013427B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/44—Mixers in which the components are pressed through slits
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/27—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices
    • B01F27/271—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices with means for moving the materials to be mixed radially between the surfaces of the rotor and the stator
    • B01F27/2711—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices with means for moving the materials to be mixed radially between the surfaces of the rotor and the stator provided with intermeshing elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/81—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
    • B01F33/811—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles in two or more consecutive, i.e. successive, mixing receptacles or being consecutively arranged
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Colloid Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Edible Oils And Fats (AREA)
  • Display Devices Of Pinball Game Machines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Liquid Carbonaceous Fuels (AREA)

Abstract

circulação das componentes durante a homogeneização de emulsões. um método melhorado para a fabricação de uma emulsão de óleo-em-água envolvendo a circulação dos componentes da emulsão entre um primeiro recipiente e um segundo recipiente através de um homogeneizador e/ou através de um dispositivo de microfluidização. utilmente, todos os componentes da emulsão a partir do primeiro recipiente são esvaziados, antes de serem devolvidos.
BR112012013427A 2009-12-03 2010-12-03 circulação dos componentes durante a homogeneização de emulsões BR112012013427B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28351809P 2009-12-03 2009-12-03
US61/283,518 2009-12-03
PCT/IB2010/003394 WO2011067673A2 (en) 2009-12-03 2010-12-03 Circulation of components during homogenization of emulsions

Publications (3)

Publication Number Publication Date
BR112012013427A2 true BR112012013427A2 (pt) 2016-04-05
BR112012013427B1 BR112012013427B1 (pt) 2021-03-30
BR112012013427B8 BR112012013427B8 (pt) 2021-05-25

Family

ID=43923723

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012013427A BR112012013427B8 (pt) 2009-12-03 2010-12-03 circulação dos componentes durante a homogeneização de emulsões

Country Status (25)

Country Link
US (6) US8895629B2 (pt)
EP (4) EP4410306A3 (pt)
JP (2) JP5820390B2 (pt)
KR (1) KR101523215B1 (pt)
CN (2) CN102753149B (pt)
AU (1) AU2010325752B2 (pt)
BR (1) BR112012013427B8 (pt)
CA (1) CA2782511C (pt)
DK (2) DK2638895T3 (pt)
EA (1) EA024770B1 (pt)
ES (3) ES2975170T3 (pt)
FI (1) FI2638895T3 (pt)
HK (2) HK1160396A1 (pt)
HR (1) HRP20130398T1 (pt)
HU (1) HUE066873T2 (pt)
IL (1) IL219984B (pt)
MX (3) MX2012006216A (pt)
NZ (1) NZ600323A (pt)
PL (1) PL2356983T3 (pt)
PT (1) PT2356983E (pt)
RS (1) RS52748B (pt)
SG (2) SG10201501611QA (pt)
SI (2) SI2356983T1 (pt)
SM (1) SMT201300044B (pt)
WO (1) WO2011067673A2 (pt)

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USRE46441E1 (en) 2017-06-20
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