BR0317957A - Processo para fabricar um b-hidroxinitrilo solúvel em água - Google Patents

Processo para fabricar um b-hidroxinitrilo solúvel em água

Info

Publication number
BR0317957A
BR0317957A BR0317957-5A BR0317957A BR0317957A BR 0317957 A BR0317957 A BR 0317957A BR 0317957 A BR0317957 A BR 0317957A BR 0317957 A BR0317957 A BR 0317957A
Authority
BR
Brazil
Prior art keywords
hydroxynitrile
making
water soluble
water
soluble
Prior art date
Application number
BR0317957-5A
Other languages
English (en)
Inventor
Carl Henry Behrens
James Mencel
Original Assignee
Rhodia Pharma Solutions Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhodia Pharma Solutions Inc filed Critical Rhodia Pharma Solutions Inc
Publication of BR0317957A publication Critical patent/BR0317957A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/16—Preparation of carboxylic acid nitriles by reaction of cyanides with lactones or compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/32—Separation; Purification; Stabilisation; Use of additives
    • C07C253/34—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/11—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton
    • C07C255/12—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton containing cyano groups and hydroxy groups bound to the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Epoxy Compounds (AREA)

Abstract

"PROCESSO PARA FABRICAR UM <225>-HIDROXINITRILO SOLúVEL EM áGUA". Um processo para fabricar um <225>-hidroxinitrilo solúvel em água. Um 1,2-epóxido e um sal de cianeto inorgânico são reagidos em um solvente tendo metanol aquoso e um tampão para formar um <225>-hidroxinitrilo. O tampão substancialmente impede a formação de produtos de reação exceto <225>hidroxinitrilo. Opcionalmente, água pode ser removida do <225>hidroxinitrilo por destilação azeotrópica com acetonitrilo e subseq³entemente purificada por meio de filtração e destilação à vácuo.
BR0317957-5A 2003-01-08 2003-12-10 Processo para fabricar um b-hidroxinitrilo solúvel em água BR0317957A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/338,814 US6960680B2 (en) 2003-01-08 2003-01-08 Manufacture of water-soluble β-hydroxynitriles
PCT/US2003/039084 WO2004063144A1 (en) 2003-01-08 2003-12-10 MANUFACTURE OF WATER-SOLUBLE β-HYDROXYNITRILES

Publications (1)

Publication Number Publication Date
BR0317957A true BR0317957A (pt) 2005-11-29

Family

ID=32681512

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0317957-5A BR0317957A (pt) 2003-01-08 2003-12-10 Processo para fabricar um b-hidroxinitrilo solúvel em água

Country Status (9)

Country Link
US (1) US6960680B2 (pt)
EP (1) EP1581482A4 (pt)
JP (1) JP2006513246A (pt)
KR (1) KR20050096121A (pt)
CN (1) CN1325470C (pt)
AU (1) AU2003297766A1 (pt)
BR (1) BR0317957A (pt)
CA (1) CA2512265A1 (pt)
WO (1) WO2004063144A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003195810A (ja) * 2001-12-28 2003-07-09 Casio Comput Co Ltd 駆動回路、駆動装置及び光学要素の駆動方法
JP4610843B2 (ja) * 2002-06-20 2011-01-12 カシオ計算機株式会社 表示装置及び表示装置の駆動方法
JP4203656B2 (ja) * 2004-01-16 2009-01-07 カシオ計算機株式会社 表示装置及び表示パネルの駆動方法
JP4665419B2 (ja) * 2004-03-30 2011-04-06 カシオ計算機株式会社 画素回路基板の検査方法及び検査装置
ES2567197T3 (es) 2005-04-28 2016-04-20 Viiv Healthcare Company Derivado de carbamoilpiridona policíclico que tiene actividad inhibidora de la integrasa del VIH
EP3947336B1 (en) * 2019-04-02 2023-03-15 Evonik Operations GmbH Process for preparing 3-hydroxy-3-methylbutyrate (hmb) and salts thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3734219A1 (de) 1987-10-09 1989-04-20 Degussa Optisch aktive 2,3-epoxyalkylammoniumsulfonate, verfahren zu ihrer herstellung und verwendung
US5136079A (en) * 1991-02-26 1992-08-04 Eli Lilly And Company Regioselective synthesis
JP2734876B2 (ja) 1992-05-14 1998-04-02 ダイソー株式会社 光学活性４−クロロ−３−ヒドロキシブチロニトリルの製造方法
JP2000063321A (ja) * 1998-08-21 2000-02-29 Nagase & Co Ltd 光学純度の高い長鎖β−ヒドロキシカルボン酸の製造方法
KR100313668B1 (ko) 1999-02-03 2001-11-26 박영구 (ｒ)-4-시아노-3-히드록시부티르산 에스테르의 제조방법
KR100367986B1 (ko) 2000-03-27 2003-01-14 국제약품공업주식회사 광학활성을 갖는 시아노부탄트리올 유도체 및 그의 제조방법

Also Published As

Publication number Publication date
US20040133029A1 (en) 2004-07-08
JP2006513246A (ja) 2006-04-20
EP1581482A1 (en) 2005-10-05
US6960680B2 (en) 2005-11-01
CN1735590A (zh) 2006-02-15
CN1325470C (zh) 2007-07-11
WO2004063144A1 (en) 2004-07-29
EP1581482A4 (en) 2007-04-04
CA2512265A1 (en) 2004-07-29
AU2003297766A1 (en) 2004-08-10
KR20050096121A (ko) 2005-10-05

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012.