BR0312804A - Processo para identificação de substâncias - Google Patents

Processo para identificação de substâncias

Info

Publication number
BR0312804A
BR0312804A BR0312804-0A BR0312804A BR0312804A BR 0312804 A BR0312804 A BR 0312804A BR 0312804 A BR0312804 A BR 0312804A BR 0312804 A BR0312804 A BR 0312804A
Authority
BR
Brazil
Prior art keywords
substance identification
activity
cell
cell replication
modify
Prior art date
Application number
BR0312804-0A
Other languages
English (en)
Inventor
Sabine Gratzer
Meltsje De Hoop
Bernhard Mai
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of BR0312804A publication Critical patent/BR0312804A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
    • G01N2333/39—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts
    • G01N2333/395—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts from Saccharomyces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

"PROCESSO PARA IDENTIFICAçãO DE SUBSTâNCIAS". A presente invenção refere-se a um processo celular para identificação de substâncias que são capazes de influenciar a atividade de uma molécula alvo, sendo que as células a ser analisadas contêm pelo menos um gene indicador e a atividade da referida molécula alvo afeta a multiplicação celular, com as etapas de contatar pelo menos uma célula com a substância a ser testada, detectar a multiplicação celular e detectar a atividade do produto de gene indicador.
BR0312804-0A 2002-07-23 2003-07-14 Processo para identificação de substâncias BR0312804A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10233516A DE10233516A1 (de) 2002-07-23 2002-07-23 Verfahren zur Identifizierung von Substanzen
PCT/EP2003/007569 WO2004019036A2 (de) 2002-07-23 2003-07-14 Verfahren zur identifizierung von substanzen

Publications (1)

Publication Number Publication Date
BR0312804A true BR0312804A (pt) 2005-04-19

Family

ID=30128304

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0312804-0A BR0312804A (pt) 2002-07-23 2003-07-14 Processo para identificação de substâncias

Country Status (17)

Country Link
US (1) US8642259B2 (pt)
EP (1) EP1527340B1 (pt)
JP (1) JP4546827B2 (pt)
KR (1) KR101089048B1 (pt)
CN (1) CN100397078C (pt)
AT (1) ATE447176T1 (pt)
AU (1) AU2003260308B2 (pt)
BR (1) BR0312804A (pt)
CA (1) CA2493323C (pt)
DE (2) DE10233516A1 (pt)
HK (1) HK1083534A1 (pt)
IL (1) IL166345A (pt)
MX (1) MXPA05000837A (pt)
NO (1) NO20050919L (pt)
RU (1) RU2325652C2 (pt)
WO (1) WO2004019036A2 (pt)
ZA (1) ZA200500326B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060246417A1 (en) * 2005-04-30 2006-11-02 Ok-Kyu Song System for functional analysis of polypeptides
FR3069644B1 (fr) * 2017-07-28 2024-07-12 Cisbio Bioassays Methode pour mesurer la modulation de l'activation d'un recepteur couple a une proteine g

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3429823A1 (de) * 1984-08-14 1986-02-27 Merck Patent Gmbh, 6100 Darmstadt Mittel und verfahren zum nachweis antimikrobiell wirksamer substanzen
US5885769A (en) * 1991-02-14 1999-03-23 Schering Corporation Screening systems
IL110298A (en) 1993-07-13 1999-04-11 Brann Mark Robert Identification of ligands by selective amplification of cells transfected with receptors
US5691188A (en) * 1994-02-14 1997-11-25 American Cyanamid Company Transformed yeast cells expressing heterologous G-protein coupled receptor
US5728534A (en) * 1996-07-19 1998-03-17 New England Medical Center Hospitals, Inc. Methods for identifying cardiovascular therapeutic agents
CN1107870C (zh) * 1996-09-20 2003-05-07 奥索·麦克尼尔药品公司 用于体外测定红细胞生成素生物活性的方法及其试剂盒
WO1998016557A1 (en) * 1996-10-11 1998-04-23 The General Hospital Corporation Assays for g-protein-linked receptors
GB9719496D0 (en) * 1997-09-13 1997-11-19 Glaxo Group Ltd G protien chimeras
EP0974649A1 (en) * 1998-06-22 2000-01-26 Universität Zürich Screening system
WO2000012705A2 (en) * 1998-09-01 2000-03-09 Basf Aktiengesellschaft Methods for improving the function of heterologous g protein-coupled receptors
US6063578A (en) * 1998-10-22 2000-05-16 Signal Pharmaceuticals, Inc. Dual reporter system and methods of use therefor
DE10056899A1 (de) * 2000-11-16 2002-05-29 Aventis Pharma Gmbh Promotor zur funktionellen Charakterisierung von G-Protein gekoppelten Rezeptoren in der Hefe Saccharomyces cerevisiae
US20050118690A1 (en) * 2001-10-09 2005-06-02 Shannon Roberts Love variant regulator molecules

Also Published As

Publication number Publication date
DE10233516A1 (de) 2004-02-12
US8642259B2 (en) 2014-02-04
ZA200500326B (en) 2006-07-26
ATE447176T1 (de) 2009-11-15
AU2003260308B2 (en) 2009-03-26
JP4546827B2 (ja) 2010-09-22
AU2003260308A1 (en) 2004-03-11
EP1527340A2 (de) 2005-05-04
CA2493323C (en) 2012-04-17
JP2005533523A (ja) 2005-11-10
DE50312072D1 (de) 2009-12-10
RU2325652C2 (ru) 2008-05-27
US20040092474A1 (en) 2004-05-13
KR101089048B1 (ko) 2011-12-02
IL166345A0 (en) 2006-01-16
RU2005104955A (ru) 2005-10-10
CN1672046A (zh) 2005-09-21
CN100397078C (zh) 2008-06-25
WO2004019036A3 (de) 2004-05-13
EP1527340B1 (de) 2009-10-28
MXPA05000837A (es) 2005-04-19
WO2004019036A2 (de) 2004-03-04
IL166345A (en) 2011-11-30
NO20050919L (no) 2005-04-14
HK1083534A1 (en) 2006-07-07
KR20050025648A (ko) 2005-03-14
CA2493323A1 (en) 2004-03-04

Similar Documents

Publication Publication Date Title
DE60028732D1 (de) Verfahren zur erhaltung der dns-integrität
ATE409236T1 (de) Derivatisierte nukleinsäuren und deren verwendung
BR9707948A (pt) Processo para obter plantas transplastômicas
WO2003062462A3 (en) Method for isolating nucleic acids and protein from a single sample
ATE210192T1 (de) VERFAHREN ZUR DIREKTEN SEQUENZIERUNG WÄHREND ßTEMPLATEß-AMPLIFIKATION
DE60222503D1 (de) Vorrichtung, Computerprogrammprodukt und Verfahren zur Anzeige von navigationsleistungsabhängigen Flugbahnabweichungsdaten
DE602004021185D1 (de) Auf bio-barcodes beruhender nachweis von zielanalyten
WO2006071903A3 (en) Cell based methods and systems for the identification of rna regulatory sequences and compounds that modulate their functions
DE69918089D1 (de) Btk inhibitoren und verfahren zur identifizierung und verwendung
ES2145580T3 (es) Metodos y composiciones para analizar moleculas de acido nucleico que emplean tecnicas basadas en el tamaño.
AU2003261168A1 (en) Strategies for gene expression analysis
DE50011459D1 (de) Verfahren und vorrichtung zur clusterfragmentation
ATE381552T1 (de) Derivate von 1-piperazin- und 1- homopiperazincarboxylaten, verfahren zu deren herstellung und deren verwendung als inhibitoren des faah-enzyms
ATE365319T1 (de) Methode zur identifizierung von regulatoren der bildung von protein-age-derivaten
DE602004006972D1 (de) Pet-chews und verfahren zum herstellen von pet-chews
WO2003085374A3 (en) Multiplexed assays using electrophoretically separated molecular tags
EP1343006A4 (en) METHOD FOR DETERMINING THE PROFILE OF A PROTEIN
BR0209929A (pt) Biomarcador, métodos para identificar microorganismos, e toxinas maromoleculares, e, aparelho para a realização automática do método
BR0312804A (pt) Processo para identificação de substâncias
ATE498682T1 (de) Zweidimensionale strangform- und längenabhängige trennung von nukleinsäurefragmenten
WO2001021839A3 (en) Gene expression profiles
WO2004087069A3 (en) METHODS OF IDENTIFYING COMPOUNDS THAT TARGET tRNA SPLICING ENDONUCLEASE AND USES OF SAID COMPOUNDS AS ANTI-PROLIFERATIVE AGENTS
BRPI0515397B8 (pt) métodos para detecção e identificação específicas de streptococcus agalactiae usando atividade de esterase, e meio de reação
BR0213191B1 (pt) processo para reciclagem de gás de processo em um processo eletroquìmico.
DE60333101D1 (de) Ierten organismen

Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: SANOFI-AVENTIS DEUTSCHLAND GMBH (DE)

Free format text: ALTERADO DE: AVENTIS PHARMA DEUTSCHLAND GMBH

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2314 DE 12-05-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.