NO20050919L - Fremgangsmate for identifisering av stoffer - Google Patents

Fremgangsmate for identifisering av stoffer

Info

Publication number
NO20050919L
NO20050919L NO20050919A NO20050919A NO20050919L NO 20050919 L NO20050919 L NO 20050919L NO 20050919 A NO20050919 A NO 20050919A NO 20050919 A NO20050919 A NO 20050919A NO 20050919 L NO20050919 L NO 20050919L
Authority
NO
Norway
Prior art keywords
substances
identification
activity
cell
cell replication
Prior art date
Application number
NO20050919A
Other languages
English (en)
Inventor
Sabine Gratzer
Meltsje De Hoop
Bernhard Mai
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Publication of NO20050919L publication Critical patent/NO20050919L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37—Assays involving biological materials from specific organisms or of a specific nature from fungi
    • G01N2333/39—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts
    • G01N2333/395—Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts from Saccharomyces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

Sammendrag 0. nr. E39065 Det er beskreve t en cellulær fremgangsmåte for identifikasjon av stoffer som er i stand til å påvirke aktiviteten av et målmolekyl, hvorved cellene som skal analyseres bærer minst et reportergen og aktiviteten av målmolekylet virker på celleproliferasjonen, med trinnene at minst en celle bringes i kontakt med stoffet som skal testes, celleproliferasjonen detekteres og aktiviteten av reportergenproduktet detekteres.
NO20050919A 2002-07-23 2005-02-21 Fremgangsmate for identifisering av stoffer NO20050919L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10233516A DE10233516A1 (de) 2002-07-23 2002-07-23 Verfahren zur Identifizierung von Substanzen
PCT/EP2003/007569 WO2004019036A2 (de) 2002-07-23 2003-07-14 Verfahren zur identifizierung von substanzen

Publications (1)

Publication Number Publication Date
NO20050919L true NO20050919L (no) 2005-04-14

Family

ID=30128304

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20050919A NO20050919L (no) 2002-07-23 2005-02-21 Fremgangsmate for identifisering av stoffer

Country Status (17)

Country Link
US (1) US8642259B2 (no)
EP (1) EP1527340B1 (no)
JP (1) JP4546827B2 (no)
KR (1) KR101089048B1 (no)
CN (1) CN100397078C (no)
AT (1) ATE447176T1 (no)
AU (1) AU2003260308B2 (no)
BR (1) BR0312804A (no)
CA (1) CA2493323C (no)
DE (2) DE10233516A1 (no)
HK (1) HK1083534A1 (no)
IL (1) IL166345A (no)
MX (1) MXPA05000837A (no)
NO (1) NO20050919L (no)
RU (1) RU2325652C2 (no)
WO (1) WO2004019036A2 (no)
ZA (1) ZA200500326B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060246417A1 (en) * 2005-04-30 2006-11-02 Ok-Kyu Song System for functional analysis of polypeptides
FR3069644B1 (fr) * 2017-07-28 2024-07-12 Cisbio Bioassays Methode pour mesurer la modulation de l'activation d'un recepteur couple a une proteine g

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3429823A1 (de) * 1984-08-14 1986-02-27 Merck Patent Gmbh, 6100 Darmstadt Mittel und verfahren zum nachweis antimikrobiell wirksamer substanzen
US5885769A (en) * 1991-02-14 1999-03-23 Schering Corporation Screening systems
US5707798A (en) 1993-07-13 1998-01-13 Novo Nordisk A/S Identification of ligands by selective amplification of cells transfected with receptors
US5691188A (en) 1994-02-14 1997-11-25 American Cyanamid Company Transformed yeast cells expressing heterologous G-protein coupled receptor
US5728534A (en) * 1996-07-19 1998-03-17 New England Medical Center Hospitals, Inc. Methods for identifying cardiovascular therapeutic agents
CN1107870C (zh) * 1996-09-20 2003-05-07 奥索·麦克尼尔药品公司 用于体外测定红细胞生成素生物活性的方法及其试剂盒
WO1998016557A1 (en) * 1996-10-11 1998-04-23 The General Hospital Corporation Assays for g-protein-linked receptors
GB9719496D0 (en) * 1997-09-13 1997-11-19 Glaxo Group Ltd G protien chimeras
EP0974649A1 (en) * 1998-06-22 2000-01-26 Universität Zürich Screening system
JP2002523090A (ja) * 1998-09-01 2002-07-30 ビーエーエスエフ アクチェンゲゼルシャフト 異種ｇタンパク質共役受容体の増強された機能的発現
US6063578A (en) * 1998-10-22 2000-05-16 Signal Pharmaceuticals, Inc. Dual reporter system and methods of use therefor
DE10056899A1 (de) 2000-11-16 2002-05-29 Aventis Pharma Gmbh Promotor zur funktionellen Charakterisierung von G-Protein gekoppelten Rezeptoren in der Hefe Saccharomyces cerevisiae
US20050118690A1 (en) * 2001-10-09 2005-06-02 Shannon Roberts Love variant regulator molecules

Also Published As

Publication number Publication date
RU2325652C2 (ru) 2008-05-27
DE10233516A1 (de) 2004-02-12
ATE447176T1 (de) 2009-11-15
MXPA05000837A (es) 2005-04-19
ZA200500326B (en) 2006-07-26
KR20050025648A (ko) 2005-03-14
JP4546827B2 (ja) 2010-09-22
RU2005104955A (ru) 2005-10-10
CN100397078C (zh) 2008-06-25
CN1672046A (zh) 2005-09-21
CA2493323A1 (en) 2004-03-04
DE50312072D1 (de) 2009-12-10
CA2493323C (en) 2012-04-17
HK1083534A1 (en) 2006-07-07
IL166345A (en) 2011-11-30
KR101089048B1 (ko) 2011-12-02
US20040092474A1 (en) 2004-05-13
IL166345A0 (en) 2006-01-16
WO2004019036A3 (de) 2004-05-13
EP1527340A2 (de) 2005-05-04
AU2003260308B2 (en) 2009-03-26
EP1527340B1 (de) 2009-10-28
BR0312804A (pt) 2005-04-19
AU2003260308A1 (en) 2004-03-11
JP2005533523A (ja) 2005-11-10
US8642259B2 (en) 2014-02-04
WO2004019036A2 (de) 2004-03-04

Similar Documents

Publication Publication Date Title
DE60028732D1 (de) Verfahren zur erhaltung der dns-integrität
ATE409236T1 (de) Derivatisierte nukleinsäuren und deren verwendung
DE69918089D1 (de) Btk inhibitoren und verfahren zur identifizierung und verwendung
ATE269414T1 (de) Verfahren zur drogenuntersuchung
AU2003261168A1 (en) Strategies for gene expression analysis
DE60140120D1 (de) Toxizitätstypisierung unter verwendung von leberstammzellen
ATE381552T1 (de) Derivate von 1-piperazin- und 1- homopiperazincarboxylaten, verfahren zu deren herstellung und deren verwendung als inhibitoren des faah-enzyms
WO2004065561A3 (en) Methods for identifying compounds that modulate untranslated region-dependent gene expression and methods of using same
DE602004021185D1 (de) Auf bio-barcodes beruhender nachweis von zielanalyten
WO2003048300A3 (en) Methods of identifying cellular target molecules
WO2005042692A3 (en) A method of inhibiting the expression of genes which mediate cellular cholesterol influx in animal cells and inhibiting the production of proteins resulting from the expression of such genes using cholesterol absorption inhibitors
DE69937689D1 (de) Stabiele transfizierte zellen zum auffinden von wirkstoffen, die die mrna stabilität beeinflussen
NO20050919L (no) Fremgangsmate for identifisering av stoffer
DE60138947D1 (de) Durchmusterung von bibliotheken exprimierter dna in filamentösen pilzen mit hoher durchsatzrate
EP1343006A4 (en) METHOD FOR DETERMINING THE PROFILE OF A PROTEIN
Heidelberger et al. Mass spectrometry-based proteomics for investigating DNA damage-associated protein ubiquitylation
WO2007038414A3 (en) Mining protein interaction networks
WO2001021839A3 (en) Gene expression profiles
DE59813664D1 (de) Verfahren zum screening von antimykotisch wirkenden substanzen
WO2004087069A3 (en) METHODS OF IDENTIFYING COMPOUNDS THAT TARGET tRNA SPLICING ENDONUCLEASE AND USES OF SAID COMPOUNDS AS ANTI-PROLIFERATIVE AGENTS
WO2004087070A3 (en) METHODS OF IDENTIFYING COMPOUNDS THAT TARGET tRNA SPLICING ENDONUCLEASE AND USES OF SAID COMPOUNDS AS ANTI-FUNGAL AGENTS
BRPI0515397B8 (pt) métodos para detecção e identificação específicas de streptococcus agalactiae usando atividade de esterase, e meio de reação
AU2003241174A1 (en) Method of identifying pancreatic ductal carcinoma-specific gene using pancreatic ductal cells, method of testing for pdc using said genes, and method of screening pharmaceutical candidate compounds for treating or preventing pdc
EP1445327A4 (en) SCREENING METHOD FOR A MEDICAMENT ACTIVE ON THE CELL WALL
WO2001046468A3 (en) Screening method for ros-induced apoptosis in a cell

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application