DE50011459D1 - Verfahren und vorrichtung zur clusterfragmentation - Google Patents

Verfahren und vorrichtung zur clusterfragmentation

Info

Publication number
DE50011459D1
DE50011459D1 DE50011459T DE50011459T DE50011459D1 DE 50011459 D1 DE50011459 D1 DE 50011459D1 DE 50011459 T DE50011459 T DE 50011459T DE 50011459 T DE50011459 T DE 50011459T DE 50011459 D1 DE50011459 D1 DE 50011459D1
Authority
DE
Germany
Prior art keywords
cluster
fragmentation
analysis
reaction partner
cluster fragmentation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE50011459T
Other languages
English (en)
Inventor
Christoph Gebhardt
Hartmut Schroeder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Original Assignee
Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft zur Foerderung der Wissenschaften eV filed Critical Max Planck Gesellschaft zur Foerderung der Wissenschaften eV
Priority to DE50011459T priority Critical patent/DE50011459D1/de
Application granted granted Critical
Publication of DE50011459D1 publication Critical patent/DE50011459D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F03MACHINES OR ENGINES FOR LIQUIDS; WIND, SPRING, OR WEIGHT MOTORS; PRODUCING MECHANICAL POWER OR A REACTIVE PROPULSIVE THRUST, NOT OTHERWISE PROVIDED FOR
    • F03HPRODUCING A REACTIVE PROPULSIVE THRUST, NOT OTHERWISE PROVIDED FOR
    • F03H1/00Using plasma to produce a reactive propulsive thrust
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J27/00Ion beam tubes
    • H01J27/02Ion sources; Ion guns
    • H01J27/026Cluster ion sources
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0459Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for solid samples
    • H01J49/0463Desorption by laser or particle beam, followed by ionisation as a separate step
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05HPLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H3/00Production or acceleration of neutral particle beams, e.g. molecular or atomic beams
    • H05H3/02Molecular or atomic beam generation

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Combustion & Propulsion (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Plasma & Fusion (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
  • Treating Waste Gases (AREA)
  • Electrotherapy Devices (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
DE50011459T 1999-07-21 2000-07-20 Verfahren und vorrichtung zur clusterfragmentation Expired - Lifetime DE50011459D1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE50011459T DE50011459D1 (de) 1999-07-21 2000-07-20 Verfahren und vorrichtung zur clusterfragmentation

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19934173A DE19934173A1 (de) 1999-07-21 1999-07-21 Verfahren und Vorrichtung zur Clusterfragmentation
PCT/EP2000/006956 WO2001008196A2 (de) 1999-07-21 2000-07-20 Verfahren und vorrichtung zur clusterfragmentation
DE50011459T DE50011459D1 (de) 1999-07-21 2000-07-20 Verfahren und vorrichtung zur clusterfragmentation

Publications (1)

Publication Number Publication Date
DE50011459D1 true DE50011459D1 (de) 2005-12-01

Family

ID=7915529

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19934173A Ceased DE19934173A1 (de) 1999-07-21 1999-07-21 Verfahren und Vorrichtung zur Clusterfragmentation
DE50011459T Expired - Lifetime DE50011459D1 (de) 1999-07-21 2000-07-20 Verfahren und vorrichtung zur clusterfragmentation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19934173A Ceased DE19934173A1 (de) 1999-07-21 1999-07-21 Verfahren und Vorrichtung zur Clusterfragmentation

Country Status (6)

Country Link
US (1) US7247845B1 (de)
EP (1) EP1200984B1 (de)
JP (1) JP2003505704A (de)
AT (1) ATE308114T1 (de)
DE (2) DE19934173A1 (de)
WO (1) WO2001008196A2 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2527701A1 (en) * 2003-06-06 2005-01-06 J. Albert Schultz Gold implantation/deposition of biological samples for laser desorption three dimensional depth profiling of tissues
DE102004051785B4 (de) 2004-10-25 2008-04-24 Bruker Daltonik Gmbh Proteinprofile mit Luft-MALDI
US7723678B2 (en) * 2006-04-04 2010-05-25 Agilent Technologies, Inc. Method and apparatus for surface desorption ionization by charged particles
US8835880B2 (en) * 2006-10-31 2014-09-16 Fei Company Charged particle-beam processing using a cluster source
JP5023886B2 (ja) * 2007-08-28 2012-09-12 株式会社島津製作所 大気圧maldi質量分析装置
US9144627B2 (en) 2007-09-14 2015-09-29 Exogenesis Corporation Methods for improving the bioactivity characteristics of a surface and objects with surfaces improved thereby
US20170303383A1 (en) * 2010-08-23 2017-10-19 Exogenesis Corporation Method for neutral beam processing based on gas cluster ion beam technology and articles produced thereby
US9799488B2 (en) * 2010-08-23 2017-10-24 Exogenesis Corporation Method and apparatus for neutral beam processing based on gas cluster ion beam technology
US10825685B2 (en) 2010-08-23 2020-11-03 Exogenesis Corporation Method for neutral beam processing based on gas cluster ion beam technology and articles produced thereby
US10202684B2 (en) 2010-08-23 2019-02-12 Exogenesis Corporation Method for neutral beam processing based on gas cluster ion beam technology and articles produced thereby
US10181402B2 (en) 2010-08-23 2019-01-15 Exogenesis Corporation Method and apparatus for neutral beam processing based on gas cluster ion beam technology and articles produced thereby
CN103180030B (zh) * 2010-08-23 2017-04-12 艾克索乔纳斯公司 基于气体团簇离子束技术的中性射束处理方法和设备
US11199769B2 (en) 2010-08-23 2021-12-14 Exogenesis Corporation Method and apparatus for neutral beam processing based on gas cluster ion beam technology
US10670960B2 (en) 2010-08-23 2020-06-02 Exogenesis Corporation Enhanced high aspect ratio etch performance using accelerated neutral beams derived from gas-cluster ion beams
US10556042B2 (en) 2011-08-19 2020-02-11 Exogenesis Corporation Drug delivery system and method of manufacturing thereof
CA2845762C (en) 2011-08-22 2019-01-08 Exogenesis Corporation Drug delivery system and method of manufacturing thereof
EP2758184A4 (de) 2011-08-22 2015-06-24 Exogenesis Corp Verfahren zur verbesserung der bioaktiven eigenschaften einer oberfläche und objekte mit derartig verbesserten oberflächen
EP3699950A1 (de) 2011-12-28 2020-08-26 Micromass UK Limited Kollisionsionengenerator und separator
JP5984424B2 (ja) * 2012-02-27 2016-09-06 国立大学法人京都大学 基板洗浄方法、基板洗浄装置及び真空処理装置
DE102012008259B4 (de) 2012-04-25 2014-06-26 Bruker Daltonik Gmbh Ionenerzeugung in Massenspektrometern durch Clusterbeschuss
DE102012011648B4 (de) 2012-06-08 2018-06-14 Bruker Daltonik Gmbh Analyse von Mikroben aus Mikrokolonien mittels MALDI-Massenspektrometrie
DE102012011647B4 (de) 2012-06-08 2020-07-02 Bruker Daltonik Gmbh Analyse von Mikroben aus Mikrokolonien mittels MALDI-Massenspektrometrie
GB201307792D0 (en) * 2013-04-30 2013-06-12 Ionoptika Ltd Use of a water cluster ion beam for sample analysis
EP4174906A1 (de) 2015-03-06 2023-05-03 Micromass UK Limited Verbesserte ionisierung von gasförmigen proben
GB2552430B (en) 2015-03-06 2022-05-11 Micromass Ltd Collision surface for improved ionisation
US10026599B2 (en) 2015-03-06 2018-07-17 Micromass Uk Limited Rapid evaporative ionisation mass spectrometry (“REIMS”) and desorption electrospray ionisation mass spectrometry (“DESI-MS”) analysis of swabs and biopsy samples
KR102092047B1 (ko) * 2015-03-06 2020-03-24 마이크로매스 유케이 리미티드 생체내 내시경 조직 식별 도구
EP3265820B1 (de) 2015-03-06 2023-12-13 Micromass UK Limited Spektrometrische analyse von mikroben
EP3741303A3 (de) 2015-03-06 2020-12-30 Micromass UK Limited Chemisch geführte umgebungsionisationsmassenspektrometrie
EP3265823B1 (de) 2015-03-06 2020-05-06 Micromass UK Limited Bildgebungsplattform für umgebungsionisierungsmassenspektrometrie für direkte abbildung aus gesamtgewebe
EP3671216A1 (de) 2015-03-06 2020-06-24 Micromass UK Limited Durch bildgebung geführte umgebungsionisierungsmassenspektrometrie
WO2016142690A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Inlet instrumentation for ion analyser coupled to rapid evaporative ionisation mass spectrometry ("reims") device
CN108700590B (zh) 2015-03-06 2021-03-02 英国质谱公司 细胞群体分析
GB2551294B (en) 2015-03-06 2021-03-17 Micromass Ltd Liquid trap or separator for electrosurgical applications
US11289320B2 (en) 2015-03-06 2022-03-29 Micromass Uk Limited Tissue analysis by mass spectrometry or ion mobility spectrometry
WO2016142669A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Physically guided rapid evaporative ionisation mass spectrometry ("reims")
US10777398B2 (en) 2015-03-06 2020-09-15 Micromass Uk Limited Spectrometric analysis
GB201517195D0 (en) 2015-09-29 2015-11-11 Micromass Ltd Capacitively coupled reims technique and optically transparent counter electrode
EP3443354A1 (de) 2016-04-14 2019-02-20 Micromass UK Limited Spektrometrische analyse von pflanzen

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755344A (en) * 1980-04-11 1988-07-05 The United States Of America As Represented By The United States Department Of Energy Method and apparatus for the production of cluster ions
US4378499A (en) * 1981-03-31 1983-03-29 The Bendix Corporation Chemical conversion for ion mobility detectors using surface interactions
US5053343A (en) * 1985-02-15 1991-10-01 Environmental Technologies Group, Inc. Selective ionization of gas constituents using electrolytic reactions
IL81375A (en) * 1987-01-23 1990-11-05 Univ Ramot Method and apparatus for producing ions by surface ionization of energy-rich molecules and atoms
US4851669A (en) * 1988-06-02 1989-07-25 The Regents Of The University Of California Surface-induced dissociation for mass spectrometry
US4935623A (en) * 1989-06-08 1990-06-19 Hughes Aircraft Company Production of energetic atom beams
US5051582A (en) 1989-09-06 1991-09-24 The United States Of America As Represented By The Secretary Of The Air Force Method for the production of size, structure and composition of specific-cluster ions
US5239820A (en) 1991-11-18 1993-08-31 California Institute Of Technology Electric propulsion using C60 molecules
US5338931A (en) * 1992-04-23 1994-08-16 Environmental Technologies Group, Inc. Photoionization ion mobility spectrometer
US5780862A (en) 1994-01-11 1998-07-14 Siess; Harold E. Method and apparatus for generating ions
US5577092A (en) * 1995-01-25 1996-11-19 Kublak; Glenn D. Cluster beam targets for laser plasma extreme ultraviolet and soft x-ray sources
DE19617011C2 (de) 1996-04-27 2000-11-02 Bruker Daltonik Gmbh Matrixkomponentengemisch für die matrixunterstützte Laserdesorption und Ionisierung sowie Verfahren zur Zubereitung eines Matrixkomponentengemisches
US5767511A (en) * 1996-07-25 1998-06-16 Raytheon Company Mean cluster size determination using water capture

Also Published As

Publication number Publication date
EP1200984B1 (de) 2005-10-26
DE19934173A1 (de) 2001-01-25
ATE308114T1 (de) 2005-11-15
JP2003505704A (ja) 2003-02-12
WO2001008196A2 (de) 2001-02-01
EP1200984A2 (de) 2002-05-02
WO2001008196A3 (de) 2001-12-06
US7247845B1 (en) 2007-07-24

Similar Documents

Publication Publication Date Title
ATE308114T1 (de) Verfahren und vorrichtung zur clusterfragmentation
BR9707948A (pt) Processo para obter plantas transplastômicas
WO2004097369A3 (en) Fragmentation-based methods and systems for de novo sequencing
DE60329582D1 (de) Verfahren und vorrichtung zur cache-promotion
AU2003267263A1 (en) System for and method of gas cluster ion beam processing
AU3365095A (en) High throughput screening method for sequences or genetic alterations in nucleic acids
EP1845460A3 (de) Verfahren und Vorrichtung zur Datenverarbeitung
DE60011390D1 (de) Verfahren und vorrichtung zur identifikation oder karakterisierung von polypeptiden
AU2003234484A8 (en) Sputter coating apparatus including ion beam source(s), and corresponding method
DE59912351D1 (de) System und verfahren zur identifizierung und authentifizierung von zubehör, hilfs- und/oder betriebsstoffen für technische geräte
ATE330032T1 (de) Verfahren zur erhaltung der dns-integrität
EP1443541A3 (de) Verfahren zur Herstellung und Transmissionsbestrahlung einer Probe und geladene Teilchen-optisches System
ATE348204T1 (de) Verfahren zur gewinnung von lithium
ATE294641T1 (de) Immobilisierte ionenaustauschmateriale und verfahren zu deren herstellung
ATE425985T1 (de) Verfahren zur markierung von rns
ATE178098T1 (de) Vorrichtung zur dürchführung von magnetischen zyklusreactionen
DE60213803D1 (en) Happier mapping
NZ510873A (en) Characterising polypeptides through cleavage and mass spectrometry
AU2003211041A1 (en) Method and system for accelerating the conversion process between encryption schemes
DE69940187D1 (de) Verfahren und Vorrichtung zur Übertragung von Ionen zwischen einer Atmosphärendruckionenquelle und einem Ionenfallenmassenspektrometer
EP0964425A3 (de) Apparat zur Bearbeitung eines Werkstücks mit einem gleichmässig neutralisierten Ionenstrahl
WO2005080565A8 (ja) Dnaメチル化分析用dnaアレイ及びその製造方法並びにdnaメチル化分析方法
GB2384206A (en) Automated system for two-dimensional electrophoresis
BR0114595A (pt) Uso de um composto que rompe esteróide sexual que sinaliza para o timo no tratamento de um distúrbio de células t
MX9804459A (es) Procedimiento para el diagnostico y terapia de epitelioma.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
R082 Change of representative

Ref document number: 1200984

Country of ref document: EP

Representative=s name: KOHLER SCHMID MOEBUS PATENTANWAELTE, 70565 STUTTGA