BR0307041A - Corpos de fosfolipìdio e uso dos mesmos no tratamento de doenças inflamatórias e autoimunes - Google Patents
Corpos de fosfolipìdio e uso dos mesmos no tratamento de doenças inflamatórias e autoimunesInfo
- Publication number
- BR0307041A BR0307041A BR0307041-7A BR0307041A BR0307041A BR 0307041 A BR0307041 A BR 0307041A BR 0307041 A BR0307041 A BR 0307041A BR 0307041 A BR0307041 A BR 0307041A
- Authority
- BR
- Brazil
- Prior art keywords
- inflammatory
- bodies
- treatment
- autoimmune diseases
- synthetic
- Prior art date
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G19/00—Compounds of tin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
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- A61P9/06—Antiarrhythmics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61P9/12—Antihypertensives
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
- B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
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- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G15/00—Compounds of gallium, indium or thallium
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D5/00—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
- C09D5/24—Electrically-conducting paints
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Nanotechnology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Dispersion Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Rheumatology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
Abstract
"CORPOS DE FOSFOLIPìDIO E USO DOS MESMOS NO TRATAMENTO DE DOENçAS INFLAMATóRIAS E AUTOIMUNES". A presente invenção se refere a composições sintéticas e semi-sintéticas tendo atividade biológica e aos usos das mesmas no tratamento e/ou profilaxia de vários distúrbios em pacientes mamífero. Mais particularmente, ela se refere ao preparo e uso de corpos sintéticos e semi-sintéticos os quais, após introdução no corpo de um paciente, produzem efeitos anti-inflamatórios, órgão-protetores e regulatórios imunes benéficos. A invenção também se refere a tratamentos e composições para alívio de doenças inflamatórias e autoimunes e seus sintomas.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002368656A CA2368656A1 (en) | 2002-01-21 | 2002-01-21 | Receptor-ligand pairing for anti-inflammatory response |
US5138102A | 2002-01-22 | 2002-01-22 | |
US35142702P | 2002-01-28 | 2002-01-28 | |
US36462002P | 2002-03-18 | 2002-03-18 | |
US37210602P | 2002-04-15 | 2002-04-15 | |
US40085702P | 2002-08-02 | 2002-08-02 | |
PCT/CA2003/000064 WO2003061666A1 (en) | 2002-01-21 | 2003-01-21 | Phospholipid bodies and use thereof in the treatment of inflammatory and autoimmune diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0307041A true BR0307041A (pt) | 2004-10-26 |
Family
ID=27617925
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0307018-2A BR0307018A (pt) | 2002-01-21 | 2003-01-21 | Corpos e veìculos farmaceuticamente aceitáveis de fosfato-glicerol |
BR0307041-7A BR0307041A (pt) | 2002-01-21 | 2003-01-21 | Corpos de fosfolipìdio e uso dos mesmos no tratamento de doenças inflamatórias e autoimunes |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0307018-2A BR0307018A (pt) | 2002-01-21 | 2003-01-21 | Corpos e veìculos farmaceuticamente aceitáveis de fosfato-glicerol |
Country Status (14)
Country | Link |
---|---|
US (3) | US20030175334A1 (pt) |
EP (2) | EP1467740A1 (pt) |
JP (2) | JP2005515243A (pt) |
KR (1) | KR20040089118A (pt) |
CN (1) | CN1620301A (pt) |
AR (2) | AR047005A1 (pt) |
BR (2) | BR0307018A (pt) |
CA (5) | CA2368656A1 (pt) |
EA (1) | EA007426B1 (pt) |
MA (1) | MA27168A1 (pt) |
MX (1) | MXPA04007042A (pt) |
PE (1) | PE20030973A1 (pt) |
TW (2) | TWI283181B (pt) |
WO (3) | WO2003061667A1 (pt) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050058698A1 (en) * | 2002-01-21 | 2005-03-17 | Nolan Yvonne Mairead | Pharmaceutically acceptable phosphate-glycerol carrying bodies and uses relating to Parkinson's Disease |
WO2004082688A1 (en) * | 2003-03-20 | 2004-09-30 | Vasogen Ireland Limited | Phosphatidylglycerol (pg) receptor agonists and antagonists |
EA200600297A1 (ru) * | 2003-07-21 | 2006-08-25 | Васоджен Айеленд Лимитед | Лечение острого воспалительного состояния |
US20060008517A1 (en) * | 2004-07-09 | 2006-01-12 | Lynch Marina A | Treatment of age-related memory impairment |
WO2006029886A1 (en) * | 2004-09-15 | 2006-03-23 | Vasogen Ireland Limited | Multiple sclerosis treatment |
WO2006107107A1 (ja) * | 2005-04-01 | 2006-10-12 | Fumitaka Ohsuzu | リン脂質小胞体を含む心筋保護剤および虚血・再潅流時の心筋障害を予防する方法 |
EP1928420A1 (en) * | 2005-09-26 | 2008-06-11 | Vasogen Ireland Limited | Treatment of inflammation and vascular abnormalities of the eye |
WO2007044748A2 (en) * | 2005-10-11 | 2007-04-19 | University Of Pittsburgh | Sphingomyelin liposomes for the treatment of hyperactive bladder disorders |
WO2007131329A1 (en) * | 2006-05-12 | 2007-11-22 | Vasogen Ireland Limited | Treatment of ubiquitin-proteasome system dysfunction related disorders |
BR112012003834A2 (pt) * | 2009-08-21 | 2017-08-08 | Targeted Delivery Tech Limited | métodos para tratamento de distúrbios e para tratamentos de deficiências em ácidos graxos, hipertrigliceridemia ou hipercolesterolemia e pacote |
GB201205642D0 (en) | 2012-03-29 | 2012-05-16 | Sequessome Technology Holdings Ltd | Vesicular formulations |
HUE051761T2 (hu) * | 2012-06-14 | 2021-03-29 | Univ Bern | Testreszabott liposzómák bakteriális fertõzések kezelésére |
JP6417648B2 (ja) * | 2013-07-30 | 2018-11-07 | 株式会社豊田中央研究所 | エタノールアミンリン酸の利用 |
EP3135297A4 (en) * | 2014-04-04 | 2018-02-07 | Osaka University | Drug delivery promoter containing substance for activating lysophospholipid receptors |
JP6103143B1 (ja) * | 2015-05-18 | 2017-03-29 | 不二製油株式会社 | IL−1β産生抑制作用を有する食品添加用組成物 |
PL3316856T3 (pl) | 2015-06-30 | 2021-10-25 | Sequessome Technology Holdings Limited | Zmieszane formulacje |
US20200230055A1 (en) * | 2017-03-02 | 2020-07-23 | Combioxin Sa | Liposomes for inhibiting biofilm formation |
CN115531399A (zh) * | 2022-09-15 | 2022-12-30 | 首都医科大学 | 溶血磷脂酰胆碱在治疗阿尔茨海默病中的应用 |
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FR2518718A1 (fr) * | 1981-12-23 | 1983-06-24 | Djelalian Madeleine | Procede pour capter et exploiter au maximum le rayonnement solaire global, dispositifs pour la mise en oeuvre de ce procede et capteurs solaires en resultant |
US4485054A (en) * | 1982-10-04 | 1984-11-27 | Lipoderm Pharmaceuticals Limited | Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV) |
US4789633A (en) * | 1984-04-19 | 1988-12-06 | University Of Tennessee Research Corporation | Fused liposome and acid induced method for liposome fusion |
US4946787A (en) * | 1985-01-07 | 1990-08-07 | Syntex (U.S.A.) Inc. | N-(ω,(ω-1)-dialkyloxy)- and N-(ω,(ω-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor |
US5192528A (en) * | 1985-05-22 | 1993-03-09 | Liposome Technology, Inc. | Corticosteroid inhalation treatment method |
US4812314A (en) * | 1986-02-24 | 1989-03-14 | Yissum Research & Dev. Co. Of The Hebrew Univ. Of Jerusalem And Hadassah Medical Organization | Lipid replacement therapy |
US5252263A (en) * | 1986-06-16 | 1993-10-12 | The Liposome Company, Inc. | Induction of asymmetry in vesicles |
US5229376A (en) * | 1986-09-25 | 1993-07-20 | The United States Of America As Represented By The Secretary Of The Army | Encapsulated plant-derived phosphatidylinositol (PI) compositions for the prevention of mitogenically induced cell proliferation |
US4963297A (en) * | 1987-12-22 | 1990-10-16 | The Liposome Company, Inc. | Spontaneous vesticulation of multilamellar liposomes |
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FR2617170B1 (fr) * | 1987-06-25 | 1989-12-22 | Inst Nat Sante Rech Med | Nouveaux derives peptidiques et leur application notamment en therapeutique |
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-
2002
- 2002-01-21 CA CA002368656A patent/CA2368656A1/en not_active Abandoned
-
2003
- 2003-01-17 CA CA002416791A patent/CA2416791A1/en not_active Abandoned
- 2003-01-21 MX MXPA04007042A patent/MXPA04007042A/es not_active Application Discontinuation
- 2003-01-21 US US10/348,600 patent/US20030175334A1/en not_active Abandoned
- 2003-01-21 TW TW092101231A patent/TWI283181B/zh not_active IP Right Cessation
- 2003-01-21 CN CNA03802537XA patent/CN1620301A/zh active Pending
- 2003-01-21 JP JP2003561611A patent/JP2005515243A/ja active Pending
- 2003-01-21 KR KR10-2004-7011280A patent/KR20040089118A/ko not_active Application Discontinuation
- 2003-01-21 CA CA002473490A patent/CA2473490A1/en not_active Abandoned
- 2003-01-21 CA CA002471740A patent/CA2471740A1/en not_active Abandoned
- 2003-01-21 TW TW092101236A patent/TW200302281A/zh unknown
- 2003-01-21 EP EP03700265A patent/EP1467740A1/en not_active Withdrawn
- 2003-01-21 EA EA200400888A patent/EA007426B1/ru not_active IP Right Cessation
- 2003-01-21 BR BR0307018-2A patent/BR0307018A/pt not_active IP Right Cessation
- 2003-01-21 WO PCT/CA2003/000065 patent/WO2003061667A1/en active Application Filing
- 2003-01-21 CA CA002473395A patent/CA2473395A1/en not_active Abandoned
- 2003-01-21 EP EP20030700266 patent/EP1467741A1/en not_active Withdrawn
- 2003-01-21 JP JP2003561610A patent/JP2005515242A/ja active Pending
- 2003-01-21 WO PCT/CA2003/000064 patent/WO2003061666A1/en active Application Filing
- 2003-01-21 AR ARP030100172A patent/AR047005A1/es not_active Application Discontinuation
- 2003-01-21 AR ARP030100173A patent/AR038203A1/es not_active Application Discontinuation
- 2003-01-21 BR BR0307041-7A patent/BR0307041A/pt not_active IP Right Cessation
- 2003-01-21 PE PE2003000064A patent/PE20030973A1/es not_active Application Discontinuation
- 2003-01-21 US US10/348,601 patent/US20040013718A1/en not_active Abandoned
- 2003-01-21 WO PCT/CA2003/000066 patent/WO2003061620A2/en not_active Application Discontinuation
-
2004
- 2004-07-16 MA MA27788A patent/MA27168A1/fr unknown
-
2007
- 2007-11-28 US US11/946,785 patent/US20080160074A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
TW200302735A (en) | 2003-08-16 |
BR0307018A (pt) | 2005-02-09 |
US20030175334A1 (en) | 2003-09-18 |
CA2473395A1 (en) | 2003-07-31 |
US20080160074A1 (en) | 2008-07-03 |
TW200302281A (en) | 2003-08-01 |
AR038203A1 (es) | 2005-01-05 |
CA2368656A1 (en) | 2003-07-21 |
TWI283181B (en) | 2007-07-01 |
MA27168A1 (fr) | 2005-01-03 |
JP2005515242A (ja) | 2005-05-26 |
CA2416791A1 (en) | 2003-07-21 |
EP1467740A1 (en) | 2004-10-20 |
CA2471740A1 (en) | 2003-07-31 |
EP1467741A1 (en) | 2004-10-20 |
CA2473490A1 (en) | 2003-07-31 |
MXPA04007042A (es) | 2005-06-20 |
WO2003061620A3 (en) | 2003-10-16 |
EA007426B1 (ru) | 2006-10-27 |
KR20040089118A (ko) | 2004-10-20 |
US20040013718A1 (en) | 2004-01-22 |
WO2003061666A1 (en) | 2003-07-31 |
WO2003061667A1 (en) | 2003-07-31 |
PE20030973A1 (es) | 2003-12-09 |
CN1620301A (zh) | 2005-05-25 |
JP2005515243A (ja) | 2005-05-26 |
AR047005A1 (es) | 2006-01-04 |
WO2003061620A2 (en) | 2003-07-31 |
EA200400888A1 (ru) | 2005-04-28 |
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