BR0307041A - Corpos de fosfolipìdio e uso dos mesmos no tratamento de doenças inflamatórias e autoimunes - Google Patents

Corpos de fosfolipìdio e uso dos mesmos no tratamento de doenças inflamatórias e autoimunes

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Publication number
BR0307041A
BR0307041A BR0307041-7A BR0307041A BR0307041A BR 0307041 A BR0307041 A BR 0307041A BR 0307041 A BR0307041 A BR 0307041A BR 0307041 A BR0307041 A BR 0307041A
Authority
BR
Brazil
Prior art keywords
inflammatory
bodies
treatment
autoimmune diseases
synthetic
Prior art date
Application number
BR0307041-7A
Other languages
English (en)
Inventor
Anthony E Bolton
Arkady Mandel
Original Assignee
Vasogen Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vasogen Ireland Ltd filed Critical Vasogen Ireland Ltd
Publication of BR0307041A publication Critical patent/BR0307041A/pt

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01GCOMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G19/00Compounds of tin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6911Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
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    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
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    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
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    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82BNANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01GCOMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G15/00Compounds of gallium, indium or thallium
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09DCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D5/00Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
    • C09D5/24Electrically-conducting paints

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  • General Health & Medical Sciences (AREA)
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Abstract

"CORPOS DE FOSFOLIPìDIO E USO DOS MESMOS NO TRATAMENTO DE DOENçAS INFLAMATóRIAS E AUTOIMUNES". A presente invenção se refere a composições sintéticas e semi-sintéticas tendo atividade biológica e aos usos das mesmas no tratamento e/ou profilaxia de vários distúrbios em pacientes mamífero. Mais particularmente, ela se refere ao preparo e uso de corpos sintéticos e semi-sintéticos os quais, após introdução no corpo de um paciente, produzem efeitos anti-inflamatórios, órgão-protetores e regulatórios imunes benéficos. A invenção também se refere a tratamentos e composições para alívio de doenças inflamatórias e autoimunes e seus sintomas.
BR0307041-7A 2002-01-21 2003-01-21 Corpos de fosfolipìdio e uso dos mesmos no tratamento de doenças inflamatórias e autoimunes BR0307041A (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
CA002368656A CA2368656A1 (en) 2002-01-21 2002-01-21 Receptor-ligand pairing for anti-inflammatory response
US5138102A 2002-01-22 2002-01-22
US35142702P 2002-01-28 2002-01-28
US36462002P 2002-03-18 2002-03-18
US37210602P 2002-04-15 2002-04-15
US40085702P 2002-08-02 2002-08-02
PCT/CA2003/000064 WO2003061666A1 (en) 2002-01-21 2003-01-21 Phospholipid bodies and use thereof in the treatment of inflammatory and autoimmune diseases

Publications (1)

Publication Number Publication Date
BR0307041A true BR0307041A (pt) 2004-10-26

Family

ID=27617925

Family Applications (2)

Application Number Title Priority Date Filing Date
BR0307018-2A BR0307018A (pt) 2002-01-21 2003-01-21 Corpos e veìculos farmaceuticamente aceitáveis de fosfato-glicerol
BR0307041-7A BR0307041A (pt) 2002-01-21 2003-01-21 Corpos de fosfolipìdio e uso dos mesmos no tratamento de doenças inflamatórias e autoimunes

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BR0307018-2A BR0307018A (pt) 2002-01-21 2003-01-21 Corpos e veìculos farmaceuticamente aceitáveis de fosfato-glicerol

Country Status (14)

Country Link
US (3) US20030175334A1 (pt)
EP (2) EP1467740A1 (pt)
JP (2) JP2005515243A (pt)
KR (1) KR20040089118A (pt)
CN (1) CN1620301A (pt)
AR (2) AR047005A1 (pt)
BR (2) BR0307018A (pt)
CA (5) CA2368656A1 (pt)
EA (1) EA007426B1 (pt)
MA (1) MA27168A1 (pt)
MX (1) MXPA04007042A (pt)
PE (1) PE20030973A1 (pt)
TW (2) TWI283181B (pt)
WO (3) WO2003061667A1 (pt)

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US20050058698A1 (en) * 2002-01-21 2005-03-17 Nolan Yvonne Mairead Pharmaceutically acceptable phosphate-glycerol carrying bodies and uses relating to Parkinson's Disease
WO2004082688A1 (en) * 2003-03-20 2004-09-30 Vasogen Ireland Limited Phosphatidylglycerol (pg) receptor agonists and antagonists
EA200600297A1 (ru) * 2003-07-21 2006-08-25 Васоджен Айеленд Лимитед Лечение острого воспалительного состояния
US20060008517A1 (en) * 2004-07-09 2006-01-12 Lynch Marina A Treatment of age-related memory impairment
WO2006029886A1 (en) * 2004-09-15 2006-03-23 Vasogen Ireland Limited Multiple sclerosis treatment
WO2006107107A1 (ja) * 2005-04-01 2006-10-12 Fumitaka Ohsuzu リン脂質小胞体を含む心筋保護剤および虚血・再潅流時の心筋障害を予防する方法
EP1928420A1 (en) * 2005-09-26 2008-06-11 Vasogen Ireland Limited Treatment of inflammation and vascular abnormalities of the eye
WO2007044748A2 (en) * 2005-10-11 2007-04-19 University Of Pittsburgh Sphingomyelin liposomes for the treatment of hyperactive bladder disorders
WO2007131329A1 (en) * 2006-05-12 2007-11-22 Vasogen Ireland Limited Treatment of ubiquitin-proteasome system dysfunction related disorders
BR112012003834A2 (pt) * 2009-08-21 2017-08-08 Targeted Delivery Tech Limited métodos para tratamento de distúrbios e para tratamentos de deficiências em ácidos graxos, hipertrigliceridemia ou hipercolesterolemia e pacote
GB201205642D0 (en) 2012-03-29 2012-05-16 Sequessome Technology Holdings Ltd Vesicular formulations
HUE051761T2 (hu) * 2012-06-14 2021-03-29 Univ Bern Testreszabott liposzómák bakteriális fertõzések kezelésére
JP6417648B2 (ja) * 2013-07-30 2018-11-07 株式会社豊田中央研究所 エタノールアミンリン酸の利用
EP3135297A4 (en) * 2014-04-04 2018-02-07 Osaka University Drug delivery promoter containing substance for activating lysophospholipid receptors
JP6103143B1 (ja) * 2015-05-18 2017-03-29 不二製油株式会社 IL−1β産生抑制作用を有する食品添加用組成物
PL3316856T3 (pl) 2015-06-30 2021-10-25 Sequessome Technology Holdings Limited Zmieszane formulacje
US20200230055A1 (en) * 2017-03-02 2020-07-23 Combioxin Sa Liposomes for inhibiting biofilm formation
CN115531399A (zh) * 2022-09-15 2022-12-30 首都医科大学 溶血磷脂酰胆碱在治疗阿尔茨海默病中的应用

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US20080160074A1 (en) 2008-07-03
TW200302281A (en) 2003-08-01
AR038203A1 (es) 2005-01-05
CA2368656A1 (en) 2003-07-21
TWI283181B (en) 2007-07-01
MA27168A1 (fr) 2005-01-03
JP2005515242A (ja) 2005-05-26
CA2416791A1 (en) 2003-07-21
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CA2471740A1 (en) 2003-07-31
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CA2473490A1 (en) 2003-07-31
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WO2003061620A3 (en) 2003-10-16
EA007426B1 (ru) 2006-10-27
KR20040089118A (ko) 2004-10-20
US20040013718A1 (en) 2004-01-22
WO2003061666A1 (en) 2003-07-31
WO2003061667A1 (en) 2003-07-31
PE20030973A1 (es) 2003-12-09
CN1620301A (zh) 2005-05-25
JP2005515243A (ja) 2005-05-26
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